Clinical trials: Video-assisted Thoracoscopic Surgery (VATS)
Lung Tumour, Lung Metastases
Study of Use of Paravertebral Blocks for Pain Relief in Video Assisted Lung Surgery
This project involves looking at the timing of providing pain relief for patients who are having lung surgery via the use of a small camera inserted into the chest with a scope (Video assisted thorascopy).
- Trial name
- ErLaPara (NCT01621698)
- Testing
- Early paravertebral block, Late Paravertebral block.
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Lung Diseases, Interstitial, Pulmonary Nodule, Solitary
Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection
After performing VATS pulmonary wedge resections, a chest tube is routinely left in the pleural cavity to drain possible air leaks and fluid accumulations.
- Trial name
- NOTUBE (NCT00841750)
- Testing
- Do not leave a chest tube in the pleural cavity., Do leave a chest tube in the pleural cavity.
- Where
- 3 sites in Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Oftalmológica de Santander Clínica Carlos Ardila Lulle
Thoracic Anesthesia, Nerve Block
The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS
Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia.
- Conditions
- Thoracic Anesthesia, Nerve Block, Pain, Acute
- Trial name
- NCT04829409
- Testing
- Paravertebral block, ESP block, MTP block
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology
Analgesia, Thoracic
Rhomboid Intercostal and Subserratus / Paravertebral Block
Postoperative pain is a significant concern following video-assisted thoracoscopic surgery (VATS). Pain after thoracic surgery not only causes a strong stress reaction and adverse emotional experience but also affects…
- Conditions
- Analgesia, Thoracic, Anesthesia
- Trial name
- NCT06253741
- Testing
- PARAVERTEBRAL BLOCK, RHOMBOID INTERCOSTAL AND SUBSERRATUS PLANE BLOCK
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Uludag University
Lung Disease, Undergoing Thoracosocpic Surgery
Nondependent Lung Ventilation and Fluid Responsiveness
The stroke volume variation (SVV), measured using the Vigileo-FloTrac system (Edwards Lifescience, Irvine, CA), has been shown to able to predict fluid responsiveness during one-lung ventilation (OLV) in patients undergoing…
- Trial name
- NCT02191410
- Testing
- High Frequency Positive Pressure Ventilation, Continuous Positive Airway Pressure
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Acute Pain
Bi-level vs. Single Level ESB in VATS
Video assisted thoracoscopic surgery (VATS) is a minimally invasive surgery to remove lesions from the thoracic cavity. It is associated with moderate pain which can lead to pulmonary complications after surgery.
- Trial name
- NCT05294315
- Testing
- Bi-level erector spinae block, Single level erector spinae block
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pain, Postoperative, Thoracic
Erector Spinae Block Versus Surgeon Infiltration in VATS Procedures
The study is comparing the difference between erector spinae block and surgeon infiltration after VATS (Video Assisted Thoracoscopic Surgery).
- Conditions
- Pain, Postoperative, Thoracic, Acute Pain
- Trial name
- NCT03859635
- Testing
- Liposomal Bupivacaine, Bupivacaine, 0.25%, Bupivacaine, 0.5%
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Indiana University
Pericardial Effusion, Inflammatory Response After Surgery
Anesthesia Management, Inflammatory Response and Recovery After Non-intubated VATS Pericardial Window
Non-intubated video-assisted thoracoscopic surgery (NIVATS) is performed under spontaneous ventilation and avoids tracheal intubation and one-lung mechanical ventilation.
- Conditions
- Pericardial Effusion, Inflammatory Response After Surgery, Postoperative Complications, Procedural Sedation and Analgesia
- Trial name
- RNIVATS (NCT07800767)
- Testing
- Systemic opioid-based analgesia during NIVATS, Thoracic regional analgesia during NIVATS
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Postoperative Pain, Lung Cancer
Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades
To investigate the effect of liposomal bupivacaine compared with bupivacaine hydrochloride for intercostal blockades for patients undergoing Video-assisted thoracoscopic surgery.
- Conditions
- Postoperative Pain, Lung Cancer, Video Assisted Thoracoscopic Surgery, Blockades Neuromuscular
- Trial name
- NCT05038007
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Jannie Bisgaard Stæhr
Mastectomy, Upper Limb Amputation Below Elbow
Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized, Double-Masked, Sham-Controlled Study
The ultimate objective of the proposed line of research is to determine if cryoanalgesia is an effective adjunctive treatment for pain in the period immediately following various painful surgical procedures; and, if this…
- Conditions
- Mastectomy, Upper Limb Amputation Below Elbow, Upper Limb Amputation Above Elbow, Lower Limb Amputation Below Knee
- Trial name
- NCT03578237
- Testing
- Cryoneurolysis (active)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of California, San Diego
Analgesia, Pain, Postoperative
Comparison of Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block
Objective: The authors hypothesized that combined deep and superficial serratus anterior plane block (SAPB) is as effective as erector spinae plane block (ESPB) for intraoperative and postoperative analgesia for video-assisted…
- Conditions
- Analgesia, Pain, Postoperative, Thoracic, Anesthesia
- Trial name
- NCT06073197
- Testing
- erector spinae plane block, combined deep and superficial serratus anterior plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Uludag University
Lung Nodules
Pre-Emptive Parecoxib Sodium for Pain Control During CT-Guided Lung Nodule Localization
Before undergoing minimally invasive lung surgery, patients with small lung nodules often need a procedure called "CT-guided hook wire localization." This involves using a CT scanner to help doctors place a tiny wire in the lung…
- Trial name
- PEARL (NCT07675473)
- Testing
- PARECOXIB SODIUM, 0.9 % Normal Saline
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Long Jiang
Chronic Postoperative Pain
Low Dose Peri-operative IV Ketamine for Chronic Post-surgery Pain Prevention
This study will test the null hypothesis that low-dose ketamine given peri-operatively will have no effect on the development of chronic post-surgical pain, in patients undergoing thoracotomy or video assisted thoracic surgery…
- Trial name
- NCT01296347
- Testing
- Ketamine
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- Imperial College Healthcare NHS Trust
Postoperative Pain Management in Video-Assisted Thoracoscopic Surgery
Intrathecal Morphine for Recovery and Outcomes After VATS
This study will compare two different methods of pain management in patients undergoing video-assisted thoracoscopic surgery (VATS).
- Trial name
- IMPROVE-VATS (NCT07231926)
- Testing
- Intrathecal Morphine, Serratus Anterior Plane Block (SAPB) group, Dexmedetomidine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Musculoskeletal Diseases or Conditions
ITPB 1 vs 3 in VATS
This study aims to evaluate the quality of recovery after video-assisted thoracoscopic surgery (VATS) by comparing the efficacy of a single-level intertransverse process block (ITPB) against a three-level ITPB, with particular…
- Trial name
- NCT06838793
- Testing
- Single Level Intertransverse Process Block, Three Level Intertransverse Process Block
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Post Operative Pain Control
Efficacy of Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block for Postoperative Pain Control Following Video-assisted Thoracoscopic Surgeries (VATS): Randomized Control Trial
The aim of the study is to compare the analgesic efficacy of Erector spinae plane block versus Serratus anterior plane block in patients undergoing video-assisted thoracoscopic surgeries.
- Trial name
- NCT07360028
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), Serratus anterior plane block (SAP)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Postoperative Analgesia
Ketamine and Magnesium in Erector Spinae Plane Block
In this study, it will aimed to evaluate the effect of magnesium sulfate and ketamine HCl added to local anesthetic on postoperative pain management in the ultrasound-guided erector spina plane (ESP) block in patients will…
- Trial name
- NCT05855798
- Testing
- Bupivacain, Magnesium sulfate, Ketamine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Non-Small Cell Lung Cancer
Analysis of RATS, VATS and Open Lung Resections After Neoadjuvant Chemo-immunotherapy in Patients Performed in Five Referred Centers
The study is a retrospective observational study. The study is designed to be multicentric and international and it will analyze medical records from selected patients diagnosed with locally advanced and resectable NSCLC who…
- Trial name
- IMMUNORATS (NCT06626243)
- Where
- 6 sites in United States, Italy
- Volunteers
- 140 people
- Sponsor
- Scientific Institute San Raffaele
Analgetic, Lung Cancer (NSCLC)
High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy
The aim is to conduct a randomized controlled trial (RCT) with a high dose arm (1mg/kg) vs a low dose (8mg in total) of steroid (Dexamethasone) given intravenous (IV) after the induction of anesthesia to "High-pain-responders" in…
- Conditions
- Analgetic, Lung Cancer (NSCLC), Video Assisted Thoracic Surgery (VATS), Glucocorticoid
- Trial name
- DEXTER (NCT07213375)
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-operative Pain
Ultrasound Guided Erector Spinae Plane Block in Patients Undergoing VATS Lobectomy
This study will compare ESP block plus patient-controlled analgesia (PCA) to intercostal nerve block plus PCA as post-operative pain control for patients having video-assisted thorascopic surgeries.
- Trial name
- NCT03176667
- Testing
- Ultrasound guided erector spinae plane block, Intercostal block
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University