Clinical trials: Viral Load
HIV, Adherence
Evaluation of a Computer-Based System Using Cell Phones for HIV People in Peru
The investigators propose to develop and evaluate a computer-based intervention using cell phones to enhance adherence to antiretroviral treatment (ART) and support of HIV transmission risk-reduction among adult HIV-positive…
- Conditions
- HIV, Adherence, Sexual Behavior, HIV Infections
- Trial name
- Cell-POS (NCT01118767)
- Testing
- Cell phone intervention
- Where
- 2 sites in Peru
- Volunteers
- 210 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Covid19
Safety and Efficacy of Intranasal Application of GX-03 as a Treatment and Prevention for COVID-19.
Phase 2b clinical trial to evaluate the safety and efficacy of intranasal application of GX-03 as a treatment and prevention for COVID-19.
- Trial name
- NCT04951349
- Testing
- GX-03, Petrolatum ointment
- Where
- 3 sites in Panama
- Volunteers
- 85 people
- Sponsor
- Turn Therapeutics
Covid19, SARS-CoV Infection
SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial
Adults (aged 18-65 years) recently diagnosed with SARS-CoV-2 infection who use a 4-day combined intervention of nasal washes with 1% baby shampoo solution and oral gargles with Listerine Antiseptic® will have a reduced SARS-CoV-2…
- Trial name
- SNOW (NCT04802408)
- Testing
- Saline and Listerine, Saline and Saline
- Where
- 2 sites in United States
- Volunteers
- 171 people
- Sponsor
- Milton S. Hershey Medical Center
HIV Infections
A Study of Peldesine (BCX-34) in HIV-Infected Patients
The purpose of this study is to determine the highest amount of peldesine that is safe. This study will also see if this amount of peldesine is effective in lowering HIV levels in the blood.
- Trial name
- NCT00002237
- Testing
- Peldesine
- Where
- United States
- Sponsor
- BioCryst Pharmaceuticals
HIV Infections
A Study of 1592U89 in HIV-Infected Adults
The purpose of this study is to see if it is safe and effective to give 1592U89 to HIV-positive adults. This study also examines the influence previous anti-HIV treatment has on the effectiveness of 1592U89.
- Trial name
- NCT00002200
- Testing
- Abacavir sulfate
- Where
- United States
- Sponsor
- Glaxo Wellcome
Chronic Hepatitis C Virus Infection
Phase I/IIa Dose Ranging CHRONVAC-C® Study in Chronic HCV Patients
The purpose of this study is to evaluate if the DNA vaccine CHRONVAC-C® intended for future treatment of Hepatitis C infections is safe and tolerated when administered to HCV infected individuals with a low viral load.
- Trial name
- NCT00563173
- Testing
- CHRONVAC-C®
- Where
- 2 sites in Sweden
- Volunteers
- 12 people
- Sponsor
- Tripep AB
COVID-19 Pneumonia, COVID-19
Clinical, Virological, Serological and Immunological Characteristics During and Following COVID-19 Hospitalization
Assessment of the association between the severity of COVID-19 and SARS-CoV-2 NAb titers levels for up to six months following primary infection using a live virus NAb assay.
- Trial name
- COVISERA (NCT05274373)
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Nordsjaellands Hospital
Cytomegalovirus Infections, HIV-1-infection
Cytomegalovirus Infection in Patients With HIV-1 Infection
The purpose of this study is to assess the level of CD4 and CD8 T cell activation in an observational cohort study of HIV-1 patients, virosuppressed on combined antiretroviral therapy (< 50 copies/ml) for at least 2 years and to…
- Trial name
- ACTHIV (NCT04067869)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 392 people
- Sponsor
- University Hospital, Bordeaux
HIV Infections
Study Switching HIV-1 Infected Patients With an Undetectable Viral Load on a First Protease Inhibitor-Based Regimen to an Efavirenz-Based Regimen
The purpose of this study is to demonstrate that virologically controlled HIV-infected individuals can successfully switch from a protease inhibitor (PI)-based regimen to an efavirenz-based regimen while maintaining virologic…
- Trial name
- NCT00135382
- Testing
- Videx EC, Epivir, Sustiva
- Where
- 48 sites in United States, Puerto Rico
- Volunteers
- 254 people
- Sponsor
- Bristol-Myers Squibb
ART, HIV I Infection
Community Based Antiretroviral Therapy (CBART) Among Children on Chronic ART
A randomized, open label trial of two strategies for Virus Load Differentiated Care (VLDC) monitoring of virologic outcome in a rural community based treatment program in Zimbabwe.
- Trial name
- CBART (NCT03986099)
- Testing
- Monitoring virus load
- Where
- Zimbabwe
- Volunteers
- 451 people
- Sponsor
- Biomedical Research and Training Institute, Zimbabwe
HIV Infections
A Pilot Study of the Short-Term Effects of Antiretroviral Management Based on Plasma Genotypic Antiretroviral Resistance Testing (GART) Compared With Antiretroviral Management Without Plasma GART
To determine the short-term virologic and immunologic effects of using plasma genotypic antiretroviral resistance testing (GART) results (interpreted by study virologists AS PER AMENDMENT 9/17/97) in the management of therapy for…
- Trial name
- NCT00000874
- Where
- 24 sites in United States
- Volunteers
- 148 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include Amprenavir
This study will compare the safety and effectiveness of two anti-HIV drug combinations in fighting HIV infection in patients whose viral loads (levels of HIV in the blood) rose with other anti-HIV drug treatments.
- Trial name
- NCT00002423
- Testing
- Indinavir sulfate, Abacavir sulfate, Amprenavir
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Glaxo Wellcome
HIV/AIDS
Reaching 90% HIV Suppression: The Role of POC Viral Load Monitoring in Nigeria
The UNAIDS 90-90-90 goals represents an ambitious strategy to end the acquired immunodeficiency syndrome (AIDS) epidemic by 2020 [UNAIDS, 2015].
- Trial name
- POC (NCT03533868)
- Testing
- Point-of-care viral load monitoring test
- Where
- 2 sites in Nigeria
- Volunteers
- 543 people
- Sponsor
- Harvard School of Public Health (HSPH)
COVID-19
A Trial of Ciclesonide in Adults With Mild-to-moderate COVID-19
According to In vitro studies, ciclesonide showed good antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Trial name
- NCT04330586
- Testing
- Ciclesonide Metered Dose Inhaler [Alvesco]
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Korea University Guro Hospital
HIV Infections
The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention Treatment
The purpose of this study is to see if it is safe and effective to give indinavir plus ritonavir plus 2 NRTIs to HIV-infected patients who need early intervention treatment.
- Trial name
- NCT00005118
- Testing
- Indinavir sulfate, Ritonavir
- Where
- 40 sites in United States
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Hiv Infection With Antiretroviral Therapy Indication, CD4 Below 350/µL or Below 15%
Zidovudine / Lamivudine + Nevirapine Twice Daily, Versus Tenofovir + Lamivudine + Nevirapine Once Daily in ARV-Naive Patients
The study will compare the immuno-virological efficacy, and safety, of a once daily antiretroviral combination (tenofovir + lamivudine + nevirapine) versus a twice daily association (fixed dose combination of…
- Trial name
- NCT00199979
- Testing
- Nevirapine
- Where
- France
- Volunteers
- 250 people
- Sponsor
- MEDEX
Spondyloarthritis, Rheumatoid Arthritis
SarS-Cov-2 Viral Infection (COVID-19) in Patients With Chronic Inflammatory Rheumatism
The purpose of this study is to assess whether immunosuppressive therapies used by patients with chronic inflammatory rheumatic diseases have an impact on the viral load and the humoral and cellular responses during viral…
- Conditions
- Spondyloarthritis, Rheumatoid Arthritis, Covid19
- Trial name
- COVIRIC (NCT04584541)
- Testing
- blood tests, Nasopharyngeal swabs, Stools
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Infections
Treatment With Interleukin-2 (IL-2) Plus Combination Anti-HIV-Drug Therapy (HAART) for Patients Formerly in ACTG 328
This study examines the long-term effects of interleukin-2 (IL-2) in combination with anti-HIV drugs, or highly active antiretroviral therapy (HAART).
- Trial name
- NCT00000923
- Testing
- Indinavir sulfate, Lamivudine, Stavudine
- Where
- 12 sites in United States
- Volunteers
- 110 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
COVID-19
Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Naso- Pharyngeal Viral Load in Patients With COVID-19
The SARS-CoV-2 coronavirus pandemic is responsible for more than 180,000 deaths worldwide and 20,000 deaths in France. To date, no treatment or vaccine has been successful.
- Trial name
- KILLER (NCT04371965)
- Testing
- Povidone-Iodine
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Poitiers University Hospital
Acute Respiratory Tract Infections
Effects of Nasal-spraying LiveSpo Navax in Treatment of Acute Respiratory Infections in Children
Rationals: Infection with the Respiratory Syncytial Virus (RSV) is one of the most common causes of respiratory tract diseases. However, treatment for pediatric RSV infection remains supportive to prevent co-infection bacteria…
- Trial name
- NCT05164692
- Testing
- LiveSpo Navax, 0.9% NaCl physiological saline
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- National Children's Hospital, Vietnam