Clinical trials: Viral Pneumonia
Sars-CoV-2 Infection
Viral Load Analysis of the SARS-CoV-2 Virus in Nose Versus Mouth Sites
It is a single-center, non-profit experimental study, intended to evaluate the viral load of SARS COV 2 in nasal and oral samples of positive subjects to evaluate any variation and understand which is the most suitable site for…
- Trial name
- NCT05769803
- Testing
- Nasal and mouth swab
- Where
- Italy
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Covid-19 Infection, Hospitalization in Respiratory Disease Department
Protective Role of Inhaled Steroids for Covid-19 Infection
We hypothesize that inhaled steroid therapy and long acting beta 2 adrenergic agonist, widely prescribed in asthma patients, may also have a local protective effect against coronavirus infection, even in patients without asthma.
- Trial name
- INHASCO (NCT04331054)
- Testing
- 2: Usual practice + SYMBICORT RAPIHALER, 1: Usual practice
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19, SARS-CoV-2 PNEUMONIA
Safety and Efficiency of Method of Exosome Inhalation in COVID-19 Associated Pneumonia
Coronavirus is an acute viral disease with prevailing upper respiratory tract infections caused by the RNA-containing virus of the genus Betacoronavirus of the Coronaviridae family.
- Conditions
- Covid19, SARS-CoV-2 PNEUMONIA, COVID-19
- Trial name
- COVID-19EXO2 (NCT04602442)
- Testing
- EXO 1 inhalation, EXO 2 inhalation
- Where
- Russia
- Volunteers
- 90 people
- Sponsor
- Olga Tyumina
SARS-CoV-2 Infection, COVID-19
Safety, Tolerability and Efficacy of Molnupiravir (EIDD-2801) to Eliminate Infectious Virus Detection in Persons With COVID-19
This was a phase IIa, double-blind, placebo-controlled, randomized trial, designed to compare the safety, tolerability, and antiviral activity of EIDD-2801 (molnupiravir) versus placebo as measured by SARS-CoV-2 viral RNA…
- Trial name
- NCT04405570
- Testing
- Molnupiravir 200 mg, Molnupiravir 400 mg, Molnupiravir 800 mg
- Where
- 10 sites in United States
- Volunteers
- 204 people
- Sponsor
- Ridgeback Biotherapeutics, LP
COVID-19
TURN-COVID Biobank: The Dutch Cohort Study for the Evaluation of the Use of Neutralizing Monoclonal Antibodies and Other Antiviral Agents Against SARS-CoV-2
Novel antiviral drugs can mark a turning point in the prevention and treatment of patients with Covid-19. Recently, several independent large phase-III RCTs have shown that the intravenous administration of one gift of…
- Trial name
- TURN-COVID (NCT05195060)
- Testing
- casirivimab with imdevimab, sotrovimab, molnupiravir
- Where
- 4 sites in Netherlands
- Volunteers
- 1,178 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
COVID-19 Convalescent Plasma Treatment
Covid-19 Convalescent Plasma and Monoclonal Antibodies Treatment of Immunocompromised Patients
Data on the use of convalescent plasma in the treatment of covid-19 are scarce: the results of randomized studies involving mainly immunocompetent patients are disappointing, while case series or retrospective data on more…
- Trial name
- Covid-IC (NCT05905380)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Hepatitis C, Chronic; AUD
Hepatitis C Alcohol Reduction Treatment
Subjects are being asked to take part in a research study to test two levels of alcohol services for patients with hepatitis C virus (HCV) who drink alcohol.
- Trial name
- HepART-RCT (NCT02176980)
- Testing
- Brief alcohol counseling, Group and Individual Therapy Sessions
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Duke University
COVID-19
BERRY- a Study of Sambucol ® in the Treatment, and Reduction of Symptoms in Participants With Coronavirus 19
Severe acute respiratory syndrome (SARS) coronavirus 2 (CoV 2) (COVID19) is a readily transmissible virus that has a wide ranging incubation period of 2-14 days. The symptoms include fever, cough and loss of taste and smell.
- Trial name
- BERRY (NCT05489770)
- Testing
- Sambucol® Black Elderberry Original (Sambucus nigra) Liquid
- Where
- United Kingdom
- Volunteers
- 204 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Covid19
Nervous System Symptoms Associated With COVID 19
This study aim to prospectively evaluate the neuropsychiatric symptoms of patients infected with the SARS-CoV-2 virus by a standardized neuropsychiatric examination : the global CASE scale (Clinical Assessment Scale in Autoimmune…
- Trial name
- NS-COV (NCT04922905)
- Testing
- NEURO +, NEURO -
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Toulouse
COVID-19 Pandemic, Professional Stress
Mental Health of Professionals of the Silver Economy of New Aquitaine : Online Survey of Accommodation Establishments for Old People and Home Assistance Establishments
The purpose of this study is identify the psychological impact of the coronavirus-19 pandemic on professionals in residential care facilities for old people and home help professionals in New-Aquitaine by : 1.
- Trial name
- SILVER NA (NCT05381883)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
COVID-19, Liver Cirrhosis
COVID-19 in Patients With Pre-existing Cirrhosis (COVID-Cirrhosis-CHESS2002): A Multicentre Observational Study
COVID-19 pandemic with SARS-CoV-2 infection has become a global challenge. Though most cases of COVID-19 are mild, the disease can also be fatal.
- Trial name
- NCT04329559
- Where
- 15 sites in China
- Volunteers
- 21 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
COVID-19
Beat COVID-19 - Observational Trial
JUPITER is an observational study protocol that aims to understand factors that can help prevent/mitigate the spread of COVID-19 and understand factors that help reduce disease progression in patients with COVID-19.
- Trial name
- JUPITER (NCT04337762)
- Where
- United States
- Volunteers
- 100,000 people
- Sponsor
- Beat COVID LLC
COVID-19
Study on Sequential Immunization of Inactivated COVID-19 Vaccine and Recombinant COVID-19 Vaccine (Ad5 Vector) in Elderly Adults
This is a randomized, observer-blind, parallel-controlled study, for evaluation of safety and immunogenicity of sequential immunization of a recombinant COVID-19 vaccine (adenovirus type 5 vector) in Chinese healthy adults aged…
- Trial name
- NCT04952727
- Testing
- Recombinant SARS-CoV-2 Ad5 vectored vaccine, Inactive SARS-CoV-2 vaccine (Vero cell)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Covid19, SARS-CoV Infection
Reactogenicity, Safety and Immunogenicity of QazCoVac-P COVID-19 Vaccine
Randomized, Blind, Placebo-controlled Phase- I Study and Randomized, Open Phase Phase-II Study of QazCoVac-P - COVID-19 Subunit Vaccine in Healthy Adult Volunteers From 18 Years Old and Elder
- Conditions
- Covid19, SARS-CoV Infection, Vaccine Adverse Reaction
- Trial name
- NCT04930003
- Testing
- QazCoVac-P -COVID-19 Subunit Vaccine
- Where
- Kazakhstan
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Research Institute for Biological Safety Problems
Covid19
The Effect of Probiotic Supplementation on SARS-CoV-2 Antibody Response After COVID-19
This study will explore how a well-known probiotic strain L. reuteri DSM 17938 impacts SARS-CoV-2 specific antibody response upon and after infection in healthy adults.
- Trial name
- NCT04734886
- Testing
- L. reuteri DSM 17938 + vitamin D
- Where
- Sweden
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Heart Disease
Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST): Prospective COVID-19 Natural History Study
Background: The COVID-19 pandemic infected and killed African Americans at higher rates than other Americans. Researchers want to understand why.
- Trial name
- NCT05484882
- Where
- 2 sites in United States
- Volunteers
- 431 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Pneumonia, Viral, Cytokine Storm
Ultra Low Doses of Therapy With Radiation Applicated to COVID-19
The host response against the coronavirus 2 (SARS-CoV-2) appears to be mediated by a 'cytoquine storm' developing a systemic inflammatory mechanism and an acute respiratory distress syndrome (ARDS), in the form of a bilateral…
- Trial name
- ULTRA-COVID (NCT04394182)
- Testing
- Ultra-Low-dose radiotherapy, ventilatory support with oxygen therapy, Lopinavir/ritonavir
- Where
- 2 sites in Spain
- Volunteers
- 15 people
- Sponsor
- Fundacion GenesisCare
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Brain Imaging in Babies Study
The aims of the BIBS Study The Brain Imaging in Babies study (BIBS) aims to improve understanding of how a baby's brain develops from before birth, up until 3-4 years of age.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Conditions, COVID-19
- Trial name
- BIBS (NCT04443179)
- Where
- United Kingdom
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- King's College London
Wellbeing of Healthcare Providersin Frontline COVID-19 Departments
Integrative Medicine Impact on Frontline COVID-19 Personnel Wellbeing
Treating COVID-19 hospitalized patients incurred heavy burden of physical and emotional stress. The present study is taking place at Carmel Medical Center in collaboration with the integrative oncology and the internal medicine…
- Trial name
- NCT05104827
- Testing
- Complementary Integrative Medicine
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Carmel Medical Center
Acute Respiratory Distress Syndrome, SARS-CoV-2
Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease
Rationale: The current SARS-CoV-2 pandemic has a high burden of morbidity and mortality due to development of the so-called acute respiratory distress syndrome (ARDS).
- Conditions
- Acute Respiratory Distress Syndrome, SARS-CoV-2, COVID, COVID-19
- Trial name
- NCT04335786
- Testing
- Valsartan (Diovan)
- Where
- 7 sites in Netherlands
- Volunteers
- 23 people
- Sponsor
- Radboud University Medical Center
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