Clinical trials: Viral Respiratory Tract Infections
Pneumonia, Pneumocystis Carinii, HIV Infections
Dapsone 100 Mg Versus 50 as Primary Prophylaxis for Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS-Related Complex (ARC)
To determine which of 2 doses of dapsone is effective prophylaxis for Pneumocystis carinii pneumonia (PCP) in patients with oral thrush or hairy leukoplakia and less than 400 CD4 lymphocytes per mm3.
- Trial name
- NCT00002043
- Testing
- Dapsone
- Where
- United States
- Sponsor
- Jacobus Pharmaceutical
COVID-19
Community Perception on COVID-19 Prevention and Control
In times whereby COVID-19 is rapidly spreading, research on the epidemiological, diagnostic, clinical and social aspects of the illness has been highlighted as important as there is very limited information of this disease in all…
- Trial name
- NCT06452108
- Where
- Pakistan
- Volunteers
- 2,651 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Covid-19, Pneumonia
The Effects of Pulmonary Physiotherapy Treatments on Patients With COVID-19
The aim of this study is to evaluate the efficacy of pulmonary physiotherapy on respiratory functions in hospitalized patients with Novel Coronavirus 2019 pneumonia.
- Conditions
- Covid-19, Pneumonia, SARS Pneumonia
- Trial name
- NCT04357340
- Testing
- Pulmonary Physiotherapy Techniques
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
COVID-19
To Evaluate the Immunogenicity and Safety of Sequential Booster Immunization of Recombinant Novel Coronavirus Vaccine (CHO Cells) for SARS-CoV-2
An open experimental design was used in this study, and 240 subjects were planned to be enrolled. To evaluate the immunogenicity and safety of recombinant Novel Coronavirus vaccine (CHO cells) after sequential intensification in…
- Trial name
- NCT05895110
- Testing
- Recombinant Novel Coronavirus vaccine (CHO Cells)
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Covid19
Use of Inhaled High-molecular Weight Hyaluronan in Patients With Severe COVID19: Feasibility and Outcomes
To determine whether inhaled Yabro protects against progression of COVID19-induced respiratory failure preventing the passage to non-invasive ventilation (NIV) and promotes recovery from COVID19 lung disease in hospitalized…
- Trial name
- HA-COVID (NCT04830020)
- Testing
- HMW-HA
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
COVID-19
Provide Pre-approval Single-patient Expanded Access (Compassionate Use) of VYD222 for Patients With Symptomatic COVID-19 Refractory to Other Treatments
Provide pre-approval single-patient Expanded Access (Compassionate Use) of VYD222 for patients with symptomatic COVID-19 refractory to other treatments.
- Trial name
- NCT06004128
- Testing
- VYD222
- Sponsor
- Invivyd, Inc.
Covid19
Artificial Intelligence - SARS-CoV-2 (COVID-19) Risk Evaluation
The management of COVID-19 patients in overwhelmed hospital facing the pandemic is a clinical challenge. The improvement of decision making may allow a better allocation of available resources and a better treatment of patients…
- Trial name
- AI-SCoRE (NCT04834934)
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Covid19, Stress, Psychological
Psychological Impact of COVID-19 Pandemic in Healthcare Workers
Background. The current coronavirus disease (COVID-19) has a great impact worldwide. Healthcare workers play an essential role and are one of the most exposed groups.Information about the psychosocial impact on healthcare workers…
- Conditions
- Covid19, Stress, Psychological, Work Related Stress, Epidemic Disease
- Trial name
- PSIMCOV (NCT04506515)
- Testing
- Psychological stress and adaptation at work score (PSAS)
- Where
- Spain
- Volunteers
- 3,000 people
- Sponsor
- Hospital General Universitario de Valencia
Covid-19
A Study in Patients With COVID-19 and Respiratory Distress Not Requiring Mechanical Ventilation, to Compare Standard-of-care With Anakinra and Tocilizumab Treatment The Immunomodulation-CoV Assessment (ImmCoVA) Study
The study is designed as a randomized, controlled, multi-center open-label trial to compare standard-of-care (SOC) treatment with SOC + anakinra or SOC + tocilizumab treatment in hospitalized adult subjects who are diagnosed with…
- Trial name
- NCT04412291
- Testing
- Anakinra Prefilled Syringe, Tocilizumab Prefilled Syringe, Standard-of-care treatment
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska University Hospital
SARS-CoV-2 Infection, COVID-19
Effect of COVID-19 Lockdown on Alcohol and Tobacco Use in Two Chilean Universities
This is a longitudinal study of participants from two university communities in Chile. The primary objective is to examine the effect of a regional lockdown on alcohol and tobacco use, using a difference-in-difference analysis to…
- Trial name
- NCT05069090
- Testing
- Lockdown and other social distancing measures
- Where
- 2 sites in Chile
- Volunteers
- 1,038 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Aged
Effects of the Programme Developed for Sedentary Elderly in the COVID-19 Pandemic: Mobile Interventional Study
The purpose of all these applications is the same: people keep distance and isolate themselves from those in risk groups and patients.
- Trial name
- NCT05110560
- Testing
- "Stay at Home Take a Step Program (SHTSP)"
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Hyperglycemia, Covid19
Dipeptidyl Peptidase-4 Inhibitor (DPP4i) for the Control of Hyperglycemia in Patients With COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a world health issue during the last months, affecting mostly countries with a high metabolic risk, like Mexico.
- Trial name
- Covid19DPP4i (NCT04542213)
- Testing
- Linagliptin tablet, Insulin
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Covid19
Evaluation of the Sanitary Safety of a Healthcare Professional Conference Held 9-11 June 2021 in Paris
The COVID-SRLF study will evaluate the sanitary safety of the French Intensive Care Society (FICS) annual meeting held in Paris Congress Center from June 9th to June 11th 2021 in the Coronavirus Disease 2019 (COVID-2019) pandemic…
- Trial name
- COVID-FREE (NCT04918160)
- Testing
- Exposure to the FICS annual meeting (June 9-11 2021, Paris Congress Center)
- Where
- France
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- French Society for Intensive Care
Covid19
Neutralizing Antibody Level After COVID-19 Vaccination
1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2. investigate the factors on antibody titer.
- Trial name
- NCT05083026
- Testing
- COVID-19 neutralizing antibody
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Kyungpook National University Hospital
Cancer, Liver Cirrhosis
Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
To acquire blood samples from subjects for various purposes, including: i) determining the sensitivity and specificity of select DNA methylation markers for the detection of various types of cancer, ii) identifying benign…
- Conditions
- Cancer, Liver Cirrhosis, Chronic Hepatitis, Hepatitis B
- Trial name
- ELITE (NCT05181826)
- Testing
- Multi-analyte Blood Test
- Where
- 7 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- Helio Genomics
Covid19, Vaccine
Immunogenicity of the ChAdox1 n CoV-19 Vaccine With 12-dose Vial
ChAd0x1 nCoV-19 (AZD 1222) is the main vaccine that is planned to roll-out in Thailand and involve vaccinating people especially in high-risk categories.
- Conditions
- Covid19, Vaccine, Immunogenicity
- Trial name
- NCT04961385
- Testing
- Immunogenicity after first dose of participants who received first dose of ChAdox-1 n COV-19 vaccine
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
COVID-19
A Clinical Study to Evaluate the Efficacy and Safety of SIM0417 Orally Co-Administered With Ritonavir in Symptomatic Adult Participants With Mild to Moderate COVID-19
This Phase Ⅱ/Ⅲ study is to evaluate whether or not there is a difference in time recovery of COVID-19 signs and symptoms through Day 29 between SIM0417/ritonavir and placebo.
- Trial name
- NCT05506176
- Testing
- SIM0417
- Where
- 35 sites in China
- Volunteers
- 1,208 people
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Covid19
Managerial and Environmental Risk for COVID 19 in French Long Term Care Institutions
REMPAR EHPAD study addresses environmental and managerial factors associated with an outbreak of COVID 19 in French Long Term Care Institutions in the spring of 2020.
- Trial name
- REMPAR-EHPAD (NCT04579289)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Rennes University Hospital
Stroke, Acute
Covid-19 Epidemic on Acute Stroke Management
The Covid-19 pandemic is a pandemic of an emerging infectious disease, coronavirus 2019 (Covid-19), caused by the coronavirus SARS-CoV-2.
- Trial name
- Stroke-Covid19 (NCT04370197)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Influenza, Respiratory Viral Infection
Test-and-treat for Influenza in Homeless Shelters
This study is a stepped-wedge cluster-randomized trial of on-site rapid testing and treatment for influenza in homeless shelters within the Seattle area to determine whether this strategy reduced the incidence of influenza in the…
- Trial name
- NCT04141917
- Testing
- Point-of-care molecular testing and treatment of influenza
- Where
- 9 sites in United States
- Volunteers
- 1,618 people
- Sponsor
- University of Washington
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