Clinical trials: Visual Suppression
Postpartum Depression, Mood Disorders
Whole-Body Hyperthermia for Mood and Anxiety Disorders
This study aims to examine the scientific mechanisms of whole-body hyperthermia (WBH), a novel, rapidly acting, single session antidepressant and anxiolytic therapy.
- Conditions
- Postpartum Depression, Mood Disorders, Anxiety Disorders, Postpartum Anxiety
- Trial name
- NCT06144294
- Testing
- Whole-Body Hyperthermia, fMRI
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Hypertensive Phase
Safety Study of Aqueous Suppression After Ahmed Glaucoma Valve (AGV) Implantation
The AGV implant is designed to open when the IOP is between 8 mmHg and 10 mmHg, and thus maintains an IOP of 8 mmHg or higher. In the early period after glaucoma drainage device (GDD) surgery the intraocular pressure (IOP)…
- Trial name
- NCT01814514
- Testing
- Timolol-trusopt
- Where
- Iran
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Zahra Rabbani Khah
HIV Infections
Triggered Escalating Real-time Adherence (TERA) Intervention
Youth Living with HIV (YLWH) often face unique challenges achieving high and sustained rates of adherence to their antiretroviral therapy (ART).
- Trial name
- TERA (NCT03292432)
- Testing
- TERA Intervention (TERA), Standard of Care (SOC)
- Where
- 8 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Vascular Function, Atherothrombosis
Effect of Fire Suppression and Emergency Duties on Vascular Function
Firefighters are at increased risk of death from heart attacks when compared to other emergencyy service professionals whose jobs involve similar components such as emergency call-outs and shift work.
- Trial name
- NCT01805063
- Testing
- Forearm Vascular Study, Badimon Chamber
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Visual Acuity
Objective Visual Acuity Measurement Using Suppression of the Optokinetic Nystagmus (OKN).
Suppression of the optokinetic nystagmus when a target is perceived can be applied to assess visual acuity objectively. Our aim is to establish prediction intervals for this optokinetic nystagmus suppression test (Speedwheel…
- Trial name
- Speedwheel (NCT04642495)
- Testing
- Visual acuity testing with SW , Landolt-"C" and Tumbling-"E" symbols
- Where
- Switzerland
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Basel
Malaria
Markers of T Cell Suppression: Antimalarial Treatment and Vaccine Responses in Healthy Malian Adults
Background: People with malaria often show altered immune responses to many illnesses and vaccines. This means that the malaria might cause immune suppression. It is not clear how or which vaccines are impacted by malaria.
- Trial name
- NCT02544048
- Where
- Mali
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Participants
Probiotics in Wellbeing
This study will investigate whether taking a probiotic supplement every day for 12 weeks can reduce low-level inflammation and improve wellbeing in generally healthy adults.
- Trial name
- NCT07840066
- Testing
- Probiotic Supplementation (Lactobacillus plantarum)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Hyperandrogenemia, Polycystic Ovary Syndrome
Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and Stimulation
Women with polycystic ovary syndrome (PCOS) often have irregular menstrual periods, too much facial and body hair, and weight gain. Women with PCOS also have a hard time becoming pregnant.
- Conditions
- Hyperandrogenemia, Polycystic Ovary Syndrome, Obesity
- Trial name
- NCT01421797
- Testing
- Dexamethasone, Cortrosyn
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Atopic Dermatitis
An Open Label, Safety Study to Assess the Potential for Adrenal Suppression.
An Open Label, Safety Study to Assess the Potential for Adrenal Suppression Following Treatment with DSXS in Patients with Atopic Dermatitis
- Trial name
- NCT02932891
- Testing
- DSXS topical
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Anesthesia
Determination of Propofol Target Concentration for Young and Elderly by Suppression Rate Analysis
Propofol's dose-response curve is know for the average adult but propofol's plasmatic concentration under total intravenous anesthesia differences between young and elderly must be modeled.
- Trial name
- NCT03283410
- Testing
- Propofol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brasilia University Hospital
Inflammatory Response, Metabolic Disturbance
Blueberries, Bananas, Exercise Recovery
The PURPOSE of this study is to investigate the combined influence of 2-weeks blueberry ingestion and banana ingestion (during exercise) on performance and in mitigating metabolic perturbation, immune dysfunction, and increase in…
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT03445234
- Testing
- Blueberry, banana, No banana
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Ovulation
A Phase 2, Dose-finding, Cross-over Study to Evaluate the Effect of a NES/E2 Transdermal Gel Delivery on Ovulation Suppression in Normal Ovulating Women
This is a Phase 2, dose-finding, cross-over study for the purposes of evaluating the effect of a NES/E2 transdermal gel delivery on ovulation suppression in normal ovulating women.
- Trial name
- NCT00796133
- Testing
- NES/E2 gel
- Where
- 3 sites in United States, Chile and 1 more
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Population Council
Female Puberty
Progesterone Suppression of Nocturnal LH Increases in Pubertal Girls
The purpose of this study is to learn more about how gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) pulses are controlled during puberty.
- Trial name
- JCM017 (NCT01773772)
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Virginia
HIV, Pre-exposure Prophylaxis
Case Management Dyad
The overall goal of this study is to test whether dyadic and focused case management coupled with contingency management will (1) improve financial wellbeing, (2) improve access to food, (3) increase linkage and retention rates…
- Conditions
- HIV, Pre-exposure Prophylaxis, Case Management, Contingency Management
- Trial name
- CM2 (NCT06162897)
- Testing
- Dyadic Case Management
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Adipose Tissue, Microbiome
The Influence of Gonadal Hormone Suppression on Adipocyte Lineage and the Microbiome
This research study plans to learn more about the role of female sex hormones on adipose tissue (or fat) and the gut microbiome (or the organisms that are in your digestive tract).
- Conditions
- Adipose Tissue, Microbiome, Menopause
- Trial name
- BATE Plus (NCT03396978)
- Testing
- GnRHag
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Ovulation Suppression
Evaluation of Pharmacodynamic Effects on Ovulation and Cycle Control
Evaluate the adequacy of ovulation suppression, cycle control, and safety of three transdermal contraceptive delivery systems (TCDSs).
- Trial name
- NCT01250210
- Testing
- levonorgestrel and ethinyl estradiol
- Where
- 11 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Agile Therapeutics
COPD
Evaluation Inhaled Corticosteroids on Exhaled Nitric Oxide Gas Exchange
To evaluate the role of inhaled corticosteroids to suppress nitric oxide gas exchange in stable patients with moderate-to-severe COPD who are current non-smokers and not on oral corticosteroids.
- Trial name
- NCT00568347
- Testing
- fluticasone 100mcg/ salmeterol 50mcg, fluticasone 250/salmeterol 50, salmeterol
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Arthur F Gelb MD
HIV Infections, Men
Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging
This study will evaluate the impact of U=U messaging and counseling on gaps in the HIV care cascade for men, including testing uptake and ART initiation (Aim 1), achieving viral suppression and retention in care (Aim 2) in two…
- Conditions
- HIV Infections, Men, Treatment Adherence
- Trial name
- NCT05602376
- Testing
- U=U testing messaging scripts, U=U adherence messaging scripts
- Where
- 2 sites in South Africa
- Volunteers
- 3,642 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Hiv
Virological Suppression in HIV Positive Patients Involved in a Novel Standardized Adherence Protocol
This study will look at virologically suppression of patients with HIV who receive pharmacist or case management care.
- Trial name
- NCT03517358
- Testing
- Service of care
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Contraception
Male Hormonal Contraceptive Development-ACY-5
The purpose of this research study is to help in the development of male contraception (birth control).
- Trial name
- ACY-5 (NCT00161447)
- Testing
- Acyline, Testosterone Gel, Depo-Medroxyprogesterone
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Washington