Clinical trials: Visual Suppression
Healthy
A Study to Investigate the Effects of Gastric Acid Suppression by Rabeprazole and BMS-986165 on How Fast and Complete The Drug is Absorbed Into the Body of Healthy Participants
The purpose of this study is to evaluate the effects of stomach acid suppression by rabeprazole and BMS-986165 on how fast and complete the drug is absorbed into the body of healthy participants.
- Trial name
- NCT03979248
- Testing
- BMS-986165, Rabeprazole
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Diabetes Mellitus, Geriatric
Burst Suppressions in Diabetic Elderly
This observational study aims to learn about the effects of diabetes mellitus in intraoperative electroencephalography (EEG) of elderly patients receiving general anesthesia.
- Conditions
- Diabetes Mellitus, Geriatric, General Anaesthesia, Electroencephalography
- Trial name
- NCT07037186
- Testing
- Electroencephalogram
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Pancreatitis, Immune Suppression
Immun Status at Pancreatitis Patients
Pancreatitis is a common complication especially in patients with gallbladder stones, most patients with biliary pancreatitis may recover spontaneously without sequelae, but in 10-20% of patients, the disease is severe and…
- Trial name
- NCT03937323
- Testing
- Blood lymphocyte subtypes and serum cytokines
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Hiv
Engaging Men Through HIV Self-Testing With Differentiated Care to Improve ART Initiation and Viral Suppression Among Men in Malawi
Men in sub-Saharan Africa who test HIV-positive continue to have poor ART initiation and retention outcomes. The proposed project will test a home-based ART intervention for men who are living with HIV compared to facility-based…
- Trial name
- NCT04858243
- Testing
- Home-Based ART, Facility-Based ART
- Where
- Malawi
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Sleep Quality
Filtered Eyewear to Prevent Light-induced Melatonin Suppression - Aim 1
The aim of this study is to determine the relative effectiveness of monocular and binocular light exposures, with and without selective blue-blocking filtering, on nocturnal melatonin suppression, subjective sleepiness, and…
- Trial name
- NCT06310135
- Testing
- Filtered Eyewear, Unfiltered Eyewear, No Filters
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Influenza
The Benefit and Harm of Fever Suppression by Antipyretics in Influenza
The purpose of this study is to investigate the potential benefits and risks of antipyretics use in naturally occurring influenza virus infections in humans.
- Trial name
- NCT01891084
- Testing
- Paracetamol, Backup NSAID ibuprofen
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Hepatitis C, HIV
A Peer-based Mobile-health Intervention to Increase Access & Adherence to Hepatitis C Treatment & HIV Viral Suppression
The purpose of this study is to test an intervention designed to train persons who inject drugs (PWID) and are infected with hepatitis C (HCV) and HIV in communication skills to 1) promote new HCV treatment and care 2) risk…
- Conditions
- Hepatitis C, HIV, Risk Reduction Behavior
- Trial name
- HCV-TTP (NCT02772328)
- Testing
- Peer Mentor
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Inflammatory Response, Metabolic Disturbance
Cranberry Ingestion and Cycling Related Immunity and Inflammation
This is a randomized, crossover clinical trial with 25 male and female cyclists. Study participants will ingest polyphenol-rich cranberry juice or placebo juice for 4 weeks under double-blinded procedures, and then crossover to…
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT05407701
- Testing
- Cranberry Juice
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Intubation, Intratracheal, Adverse Effects
The Study of Ciprofol for the Suppression of Cardiovascular Responses to Tracheal Intubation
Preliminary studies have illuminated the promising nature of ciprofol, indicating its enhanced safety spectrum, superior potency, and a diminished likelihood of experiencing injection-related discomfort.
- Trial name
- NCT06095570
- Testing
- Ciprofol, Remimazolam
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Hainan Medical University
Amblyopia
Optical Correction and Visual Functions of Adults With Amblyopia
Amblyopia is a developmental anomaly resulting from abnormal visual experiences in early life. Amblyopia causes reduced visual acuity in the absence of a pathology.
- Trial name
- SPECTRA (NCT05394987)
- Testing
- Spectacles
- Where
- 2 sites in Canada, Hong Kong
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre for Eye and Vision Research
Weight Loss
LEAN Project: Weight Loss and Appetite Suppression
The primary aim is to examine whether the intake of PhosphoLEAN is effective in aiding a cohort of women in losing weight. Participants taking the supplement will have significantly greater improvement in study outcomes than…
- Trial name
- NCT00153790
- Testing
- PhosphoLean
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Cooper Institute
Malaria
Markers of T Cell Suppression: Associations With Malaria Infection and Antimalarial Treatment in Malian Children
Background: The disease malaria can cause very serious health problems. Researchers want to see if malaria affects the way T cells and vaccines work in the body.
- Trial name
- NCT02504918
- Where
- Mali
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Inflammatory Response, Metabolic Disturbance
Beet Supplementation, Exercise, Inflammation
This study will determine if ingesting a beet-based supplement with nitrates for 2 weeks moderates exercise-induced inflammation.
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT05907135
- Testing
- Beet
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Healthy
Evaluate the Pharmacokinetics and Gonadotropin Suppression of Nestorone®-Testosterone (NES/T) Combination Gel in Men
This is a prospective, randomized, double-blinded, two-center trial to evaluate the gonadotropin suppressive activity of transdermal treatment with a combined NES/T gel, or T gel alone, for 28 days.
- Trial name
- NCT02432261
- Testing
- Nestorone® /testosterone gel, Testosterone only gel
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kimberly Myer
Diplopia, Binocular Vision Suppression
Understanding Visual Confusion Using Stereoscopic Displays
In this research study we want to test how people understand a visual scene when the same image is presented to both the eyes, but portions of these images are altered in terms of contrast, depth or in some cases motion.
- Conditions
- Diplopia, Binocular Vision Suppression, Binocular; Fusion, With Defective Stereopsis, Monocular Diplopia
- Trial name
- NCT04957745
- Testing
- Binocular visual confusion (unilateral opaque), Unilateral monocular visual confusion (unilateral see-through), Bilateral monocular visual confusion (bilateral see-through)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
HIV Seropositivity
Hybrid Type I Effectiveness-Implementation Trial of a Social Network Support Intervention
The goal of this Hybrid Type I effectiveness-implementation trial is to test an evidence-based, flexible, and tailored intervention that leverages existing social network members to promote retention in care and viral suppression…
- Trial name
- NCT05723653
- Testing
- Social Network Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Body Weight, Non-restrained Eaters
Appetite Suppression Trial With Polydextrose
Overweight and obesity are a global epidemic, which causes a rapid increase in the frequency of diabetes and cardiovascular diseases.
- Trial name
- NCT02064205
- Testing
- 12.5 g polydextrose, glucose syrup
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- W.J. Pasman
HIV/AIDS
VITAL Start: Brief Facility-based Video Intervention
This a multi-center, parallel group, randomized controlled outcome assessor blinded trial with a qualitative descriptive component that seeks to assess the effectiveness of a brief facility-based video intervention to optimize…
- Trial name
- VITAL (NCT03654898)
- Testing
- VITAL Start: Video-based pre-ART counseling, Standard of Care
- Where
- Malawi
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Healthy
The Effect of Sertindole on Sensory Gating and Cognition in Healthy Volunteers
This study aims to further validate and extend our previous findings insofar that the effect of the atypical antipsychotic and mixed 5-HT2/D2 antagonist sertindole on sensorimotor gating processes and its relationship to…
- Trial name
- NCT00612079
- Testing
- Sertindole
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Pancreatic Neoplasms, Adenocarcinoma
Perioperative Cancer Cell Dissemination and Systemic Immune Suppression in Resectable Ductal Pancreatic Adenocarcinoma
The purpose of this study is to determine whether early recurrence after curative resection of ductal pancreatic adenocarcinoma can be explained by either dissemination of cancer cells during intraoperative tumour manipulation…
- Conditions
- Pancreatic Neoplasms, Adenocarcinoma, Neoplasm Circulating Cells, Tumor Markers, Biological
- Trial name
- NCT00495924
- Testing
- Pancreatic resection (PD)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KU Leuven