Clinical trials: Visually Impaired Persons
Healthy
Impact of Osteopathic Manipulative Treatment on Pursuit Eye Movements in Healthy Human Adults
The idea that osteopathic manipulative treatments (OMTs) should have an impact on the human visual system is not new. Nevertheless, there is a lack of scientific, objective, and experimental evidence.
- Trial name
- NCT05018390
- Testing
- Osteopathic manipulative treatment
- Where
- France
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Ecole d'ostéopathie de Paris
Healthy
A Placebo-controlled Phase 1 Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects
A safety and tolerability study in healthy subjects including examination of how the body takes up, distributes, and gets rid of ACT-1014-6470
- Trial name
- NCT04608513
- Testing
- ACT-1014-6470
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Pneumonia, Respiratory Tract Diseases
Phase Ⅰa Clinical Trial of a Pneumococcal Vaccine
Infections with Streptococcus pneumoniae often cause serious health problems, especially for infants and the elderly.Failure to cover all polysaccharide types is an even greater problem with adults than with children.
- Conditions
- Pneumonia, Respiratory Tract Diseases, Respiratory Tract Infections
- Trial name
- PⅠCTPV (NCT04087460)
- Testing
- Protein based pneumococcal vaccine(Low dose), Protein based pneumococcal vaccine(Middle dose), Protein based pneumococcal vaccine(High dose)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Healthy Volunteers
Study to Assess Drug Levels, Immune Response, Safety and Tolerability of BMS-986446 in Healthy Chinese Participants.
The purpose of this study is to assess the drug levels, immune response, safety and tolerability of BMS-986446 in healthy Chinese participants.
- Trial name
- NCT07852962
- Testing
- BMS-986446
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Post Cesarean Section Patient
Efficacy of Ginger in the Prevention of Abdominal Distention in Post Cesarean Section Patient
The purpose of this study is to determine ginger is effective in the prevention of abdominal distention in post Cesarean section patient.
- Trial name
- NCT02809027
- Testing
- Ginger
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Healthy Volunteers
Pharmacokinetics, Safety and Tolerability Study of AVT02 to EU-approved and US-licensed Humira (Adalimumab)
This study has been designed as a multicentre, randomised, double-blind study of AVT02 in healthy adult subjects. The study will assess the PK, safety and tolerability of AVT02 compared to EU-Humira and US licenced Humira…
- Trial name
- NCT03849313
- Testing
- Adalimumab
- Where
- 3 sites in Australia, New Zealand
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Alvotech Swiss AG
Pathological Gambling, Gambling Disorder
Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder
Primary objective: *To determine whether treatment with naloxone hydrochloride nasal spray reduces gambling urge symptoms in patients with gambling disorder The secondary objectives of the study are: To determine the effects of…
- Conditions
- Pathological Gambling, Gambling Disorder, Opioid Antagonist, Naloxone
- Trial name
- NalGamb (NCT03430180)
- Testing
- Naloxone hydrochloride
- Where
- Finland
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Thalassemia
Study of Effects of YisuiShengxueGranules on Thalassemia
The primary objectives of this study are to evaluate whether Yisui Shengxue Granules therapy can increase the hemoglobin level in peripheral blood and alleviate the symptoms, and at the same time, evaluate its safety in the…
- Trial name
- thalessemia (NCT01549080)
- Testing
- Yisuishengxue Granule
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Influenza
Safety Study of Flufirvitide-3 Nasal Spray in Healthy Subjects
The purpose of this study is to evaluate the safety and pharmacokinetic profile of flufirvitide-3 nasal spray in healthy subjects.
- Trial name
- NCT01313962
- Testing
- Flufirvitide-3 0.05 mg single dose, Flufirvitide-3, 0.1 mg single dose, Flufirvitide-3, 0.2 mg single dose
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Autoimmune Technologies, LLC
Infection by Streptococcus Group B
Safety and Immunogenicity of a Group B Streptococcus Vaccine in Non-pregnant Women 18-40 Years of Age.
Part A: The primary objective is to evaluate the safety and tolerability of a potential vaccine against Group B streptococcus. Part B: To evaluate the long term safety profile of the GBS-NN vaccine up to one year following the…
- Trial name
- MVX13211 (NCT02459262)
- Testing
- GBS-NN vaccine
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Minervax ApS
SARS-CoV-2
Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273.214 SARS-CoV-2 (COVID-19) Vaccine in Infants
The study evaluated the safety, tolerability, reactogenicity, and effectiveness of mRNA-1273.214 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine in infants aged 12 weeks to < 6 months.
- Trial name
- BabyCOVE (NCT05584202)
- Testing
- mRNA-1273.214
- Where
- 39 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Congenital Bleeding Disorder, Congenital FXIII Deficiency
Safety and Pharmacokinetics of Recombinant Factor XIII Administration in Healthy Volunteers
This trial was conducted in Europe. The aim of this trial was to investigate safety and pharmacokinetics of multiple doses of catridecacog (recombinant factor XIII, rFXIII) in healthy volunteers.
- Conditions
- Congenital Bleeding Disorder, Congenital FXIII Deficiency, Healthy
- Trial name
- NCT01848002
- Testing
- catridecacog
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Overactive Bladder
Safety Study of hMaxi-K Gene Transfer to Treat Overactive Bladder and Detrusor Overactivity
The purpose of this study is to evaluate the safety of a new product that uses human gene transfer (called hMaxi-K) when it is given to patients with overactive bladder.
- Trial name
- NCT00495053
- Testing
- hMaxi-K
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Urovant Sciences GmbH
Temperament, Sleep
GUTLINK4KIDS Intervention
This study aims to investigate the chronic effects of prebiotic consumption on cognitive, behavioural and gut microbiome outcomes in children aged 3-5 years.
- Conditions
- Temperament, Sleep, Cognition, Emotion Regulation
- Trial name
- GUTLINK4KIDS (NCT07401212)
- Testing
- Prebiotic powder
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Reading
Pain
Radicle Relief 24_RLN: A Study Assessing the Impact of Health and Wellness Products on Pain and Related Health Outcomes.
A randomized, double-blind, placebo-controlled direct-to-consumer study assessing the impact of health and wellness products on pain and related health outcomes.
- Trial name
- NCT07160712
- Testing
- Relief Active Product 1, Relief Active Product 2, Relief Active Product 3
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Glabellar Frown Lines
Safety and Efficacy of AbobotulinumtoxinA for the Treatment of Glabellar Lines
An interventional phase 2 study to evaluate safety and efficacy of AbobotulinumtoxinA treatment for glabellar lines
- Trial name
- NCT03736928
- Testing
- AbobotulinumtoxinA dose level 1 or 2, AbobotulinumtoxinA dose 3, AbobotulinumtoxinA dose 4
- Where
- 10 sites in United States
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Neurodegenerative Diseases
A First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of ONO-2808-01 in Healthy Participants
This is a first in human study to determine the safety, tolerability and pharmacokinetics of ONO-2808 in healthy adult participants.
- Trial name
- NCT04578028
- Testing
- ONO-2808
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Genitourinary Syndrome of Menopause
MonaLisa Touch Randomized Double-Blind Placebo Controlled Study
Aim of the study: To assess the efficacy of MonaLisa Touch procedure for the management of genitourinary syndrome of menopause (GSM) in a randomized double-blind placebo controlled study.
- Trial name
- NCT03331328
- Testing
- MonaLisa Touch
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Michigan Institution of Women's Health PC
Healthy
Impact of Dietary Flavanols on Microvascular Function in Young Females During Mental Stress
The aim of this project is to examine whether flavonoids, which are small molecules naturally present in cocoa, as well as fruits and vegetables such as berries, tea, citrus fruits, apple (typically responsible for giving these…
- Trial name
- NCT07864545
- Testing
- High-flavanol cocoa powder, Low-flavanol cocoa powder
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Healthy Subjects
Study of the Safety, Tolerability, and Pharmacokinetics of LV232 Capsules in Chinese Healthy Volunteers
The study consists of 10 dose groups, 8 subjects in each group (male or female), randomly assigned to study drug or placebo group to evaluate the safety, tolerability and pharmacokinetics characteristics.
- Trial name
- NCT06070857
- Testing
- LV232
- Where
- China
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Vigonvita Life Sciences
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