Clinical trials: Visually Impaired Persons
Healthy
A Study to Assess the Effect of Single Doses of Daridorexant on Electrocardiogram Parameters in Healthy Subjects
A study to assess the effect of single doses of daridorexant on electrocardiogram parameters in healthy subjects
- Trial name
- NCT04250506
- Testing
- Daridorexant, Moxifloxacin
- Where
- Czechia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Healthy
Human Repeated Insult Patch Test (HRIPT) of Azelaic Acid Pre Foam Formulation
The purpose of this study is to determine the dermal sensitization potential of azelaic acid pre-foam formulation.
- Trial name
- NCT01430533
- Testing
- azelaic acid pre foam formulation, Vehicle pre foam formulation, Water
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Healthy
Phase 1 PK, Bioavailability, Safety Study of Clonidine MBT w Catapres in Healthy Volunteers
The purpose of this study is to determine the pharmacokinetic dose proportionality of 50 μg and 100 μg Clonidine and comparative bioavailability of clonidine with that from the Reference drug, Catapres® 100 μg oral tablets…
- Trial name
- NCT02548806
- Testing
- Clonidine MBT 50µg, Clonidine MBT 100µg, Catapres 100μg
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valerio Therapeutics
Body Weight, Body Height
Safety and Tolerance Study of Three Probiotic Strains in Infants
Study to evaluate the safety and tolerance of three probiotic bacteria intake by healthy infants. Participants are divided at random and unknown to the researchers, in four groups, three of which receive one of three probiotic…
- Conditions
- Body Weight, Body Height, Head Circumference
- Trial name
- PROBINFANT (NCT02215304)
- Testing
- Bifidobacterium longum ssp infantis R0033, Lactobacillus helveticus R0052, Bifidobacterium bifidum R0071
- Where
- Spain
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Head Lice
Clinical Endpoint Study of Ivermectin 0.5% Lotion
This clinical study is designed to evaluate the clinical (therapeutic) effect of a generic ivermectin lotion 0.5% (Actavis Laboratories UT, Inc.) relative to that of the Food and Drug Administration (FDA) Reference Listed Drug…
- Trial name
- NCT03301649
- Testing
- Generic Ivermectin Lotion 0.5%, Sklice® (Ivermectin) Lotion 0.5%, Vehicle Lotion
- Where
- United States
- Volunteers
- 905 people, healthy volunteers welcome
- Sponsor
- Actavis Inc.
Postoperative Pain
Comparison of Administation Routes of Ropivacaine
The purpose of this study is to evaluate the effect of different routes of local anaesthesia administration in laparoscopic procedures to reduce post-operative pain (intra-peritoneal infusion of Ropivacaine 0.75%, port site…
- Trial name
- NCT04459026
- Testing
- combination, infiltration, instillation
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Autoimmune Diseases, Multiple Sclerosis
First-in-Human Trial in Healthy Adult Volunteers to Evaluate Safety, Tolerability and PK of LAPIX Study Drug; LPX-TI641
A Phase I First-in-Human, Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adult Volunteers to Evaluate Safety, Tolerability, and Pharmacokinetics after Single and Multiple Oral Dose of LPX-TI641.
- Trial name
- NCT05853835
- Testing
- LPX-TI641
- Where
- 2 sites in United States, Jordan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- LAPIX Therapeutics Inc.
Vascular Stiffness
Effects of Fruit Consumption on Risk Factors of Chronic Disease
Acute, randomized, placebo controlled, double blind, postprandial crossover study in male subjects. 4 intervention arms consisting of control, orange juice, whole orange, and processed whole orange to determine the effect of the…
- Trial name
- NCT01963416
- Testing
- macro- and micro-nutrient matched control (240 ml), Orange juice, whole orange fruit
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Reading
Healthy
Safety, Pharmacodynamics, and Pharmacokinetics After Multiple Different Oral Doses of BIIB 722 CL Tablets in Healthy Volunteers
Study to assess safety, pharmacodynamics and pharmacokinetics of BIIB 722 CL
- Trial name
- NCT02268604
- Testing
- BIIB 722 CL
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Dental Plaque Accumulation, Nanoparticles
Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.
In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed…
- Conditions
- Dental Plaque Accumulation, Nanoparticles, Fluoride Varnishes
- Trial name
- NCT07180849
- Testing
- Fluoride varnish, Novel titania nanoparticle infused fluoride varnish
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Healthy Participants
Study to Demonstrate Pharmacokinetic and Pharmacodynamic Similarity Between NKF-INS(A), US-NovoLog®, and EU-NovoRapid®
Single-dose, double-blind, randomized, three-period, three-treatment, six-sequence, crossover study to demonstrate pharmacokinetic and pharmacodynamic similarity between NKF-INS(A), US-NovoLog®, and EU-NovoRapid®
- Trial name
- NCT06492226
- Testing
- NKF-INS(A), EU-NovoRapid®, US-NovoLog®
- Where
- South Africa
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Xentria, Inc.
Helicobacter Pylori Infection
The Safety and Tolerability, Pharmacokinetics of TNP-2092 Capsules in Combination With Rabeprazole Sodium Enteric-coated Tablets
A phase 1, single-center, double-blind, randomized, placebo-controlled clinical trial to evaluate the safety and tolerability, pharmacokinetics, and preliminary efficacy of multiple administrations of TNP-2092 Capsules in…
- Trial name
- NCT06337604
- Testing
- TNP-2092 capsules, Rabeprazole sodium enteric-coated tablets
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TenNor Therapeutics Inc.
Inflammatory Response, Metabolic Disturbance
Acute Inflammatory and Metabolic Effect of High Fructose Intake
Fructose consumption is associated with the development of metabolic diseases and low-grade inflammation. However, the acute effect of a single meal rich in fructose on the metabolic and inflammatory response is not fully…
- Trial name
- NCT05573438
- Testing
- Group fructose, Group Sucrose, Group Glucose
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Adaliene Versiani M. Ferreira
Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis
This is a Prospective, Controlled, Double Blinded, Single Center, Randomized, 3 Arm, Parallel Assignment, Phase 1b/2a Study to assess the safety, tolerability, and preliminary efficacy of B244 delivered as an intranasal spray in…
- Conditions
- Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen, Healthy Volunteers
- Trial name
- NCT03290248
- Testing
- B244 suspension, Vehicle
- Where
- 2 sites in United States, Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- AOBiome LLC
Healthy
A Clinical Study to Examine the Drug-drug Interactions Between ACT-541468 and Citalopram in Healthy Male and Female Subjects
A clinical study to examine the drug-drug interactions between ACT-541468 and citalopram in healthy male and female subjects
- Trial name
- NCT03907215
- Testing
- ACT541468, Citalopram
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Healthy
First in Man Trial of BI 113608
The primary objective of the current study is to investigate the safety and tolerability of BI 113608 in healthy male volunteers following oral administration of single rising doses.
- Trial name
- NCT01540825
- Testing
- BI 113608
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Acne Vulgaris
Application of Poly-herbal Powder for Treating Acne Vulgaris
Acne is a common problem in adolescence to young adult. But there is no such remedy available for acne treatment which has no side effects.
- Trial name
- NCT04949932
- Testing
- Mixed powder of Lens culinaris, Curcuma longa, Mentha arvensis, Azadirachta indica, and Trigonella foenumgraecum., Cicer arietinum powder
- Where
- Bangladesh
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Dr. Md. Shahab Uddin
Chronic Obstructive Pulmonary Disease
A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI With Next-Generation Propellant Compared With BGF MDI With HFA Propellant
The study will evaluate bioequivalence, pharmacokinetics, safety, and tolerability of Budesonide, Glycopyrronium and Formoterol (BGF) metered dose inhaler (MDI) formulated with hydrofluoroolefin (HFO) [Test] and hydrofluoroalkane…
- Trial name
- NCT05569421
- Testing
- Treatment A: BGF MDI HFO, Treatment B: BGF MDI HFA
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Subjects
UP-818-CC Injection in Healthy Chinese Subjects
The objectives of this study are to evaluate the safety, tolerability and pharmacokinetic characteristics in healthy Chinese volunteers after single and multiple dose of intravenous infusion of UP-818-CC.
- Trial name
- UP-818-CC (NCT07355621)
- Testing
- UP-818-CC injection
- Where
- China
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- EnliTISA (Shanghai) Pharmaceutical Co., Ltd.
Dietary Habits
Study to Investigate the Effect of Dietary Fibre Supplementation on Long-term Glucose Control in Prediabetic Subjects
The purpose of the study is to explore the potential metabolic health benefits of a dietary fibre intervention by using Soluble Fibre in a human intervention study in Healthy Obese Pre-diabetic participants over a period of 16…
- Trial name
- NCT05157815
- Testing
- Soluble Fibre, Calorie Matched Control
- Where
- Ireland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Tate & Lyle
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.