Clinical trials: Vitamin B 12 Deficiency
Vitamin B 12 Deficiency
Cobalamin Deficiency - Diagnosis and Therapy
In a retrospective study with existing values of vitamin B12 and holotranscobalamin 4 strategies are simulated and the results and costs are compared. Generally, cobalamin ist substituted by intramuscular administration.
- Trial name
- NCT04243707
- Where
- Switzerland
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Child Developmental Delay, Child Malnutrition
Maternal B12 Supplementation to Improve Infant B12 Deficiency and Neurodevelopment
Vitamin B12 plays a key role in the development and normal functioning of the brain and nervous system. Unborn and new-born infants derive their vitamin B12 stores almost entirely from maternal B12 stores.
- Conditions
- Child Developmental Delay, Child Malnutrition, Maternal Exposure, Vitamin B 12 Deficiency
- Trial name
- MATCOBIND (NCT03783104)
- Testing
- B12 Supplement
- Where
- 2 sites in India, Nepal
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University College, London
Vitamin B 12 Deficiency
Effects of Vitamin B12 Treatment in Singers
In this study, the investigators aim to assess if vitamin B12 treatment demonstrates a beneficial effect on voice performance. If so, they wish to examine the relationship between the vitamin B12 treatment and the study…
- Trial name
- NCT03437824
- Testing
- Cyanocobalamin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Vitamin B 12 Deficiency
The Impact of Vitamin B12 Deficiency on Infant Gut Microbiota
Vitamin B12 plays important roles in DNA synthesis and neurological functions. Vitamin B12 deficiency is one of the most common micronutrient deficiencies and it has become increasingly more frequent in infants.
- Trial name
- NCT03365583
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Marmara University
Deficiency, Vitamin, Vegan's Anemia (Vitamin B12 Deficiency)
Supplementation of Critical Nutrients in a Plant-based Diet
500 participants of the vegan/vegetarian congress VegMed are to be included, which should answer once (cross-sectional study) a medicine socio-behaviorist questionnaire on the topic "supplementation of critical nutrients in a…
- Conditions
- Deficiency, Vitamin, Vegan's Anemia (Vitamin B12 Deficiency), Deficiencies Micronutrient
- Trial name
- NCT03542591
- Testing
- Questionnaire on the topic "Supplementation of critical nutrients in a plant-based diet"
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Charite University, Berlin, Germany
Choline Deficiency, Vitamin B-12 Deficiency
Cracking the Egg Potential: Improving Young Child Nutrition in Ecuador
The proposed study will fill an important gap in the literature by examining, through a randomized controlled trial, the effect of egg consumption on biochemical markers of choline, vitamin B-12, lipids, and amino acids in young…
- Conditions
- Choline Deficiency, Vitamin B-12 Deficiency, Lipids Deficiency, Amino Acids Deficiency
- Trial name
- NCT02446873
- Testing
- Egg supplementation
- Where
- Ecuador
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus, Type 2, Vitamin B 12 Deficiency
The Vitamin B Status in Type 2 Diabetes (VITA) Study
The objective of this study was to evaluate vitamin B deficiency (particularly vitamin B6 deficiency) in diabetic patients in Germany in relation to the presence or absence of proteinuria, and global vascular risk.
- Conditions
- Diabetes Mellitus, Type 2, Vitamin B 12 Deficiency, Vitamin B 6 Deficiency
- Trial name
- VITA (NCT03447275)
- Testing
- Type 2 diabetes
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Rima Obeid
Cobalamin Deficiency
Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status
A 3 months randomized, placebo-controlled study on the effect of toothpaste fortified with vitamin B12 on vitamin B12 status markers and related metabolic markers.
- Trial name
- NCT02679833
- Testing
- Cyanocobalamin
- Where
- 2 sites in Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Obesity, Morbid, Homocystine; Metabolic Disorder
Homocysteine After Laparoscopic Roux-enY Gastric Bypass
Changes in homocysteine values after bariatric surgery remain controversially discussed. This is the first comprehensive summary to depict timeline changes in homocysteine levels following laparoscopic roux-en-Y gastric bypass.
- Conditions
- Obesity, Morbid, Homocystine; Metabolic Disorder, Bariatric Surgery Candidate, Folate Deficiency
- Trial name
- NCT03489538
- Testing
- laparoscopic long limb roux-en-Y gastric bypass
- Where
- Austria
- Volunteers
- 708 people
- Sponsor
- Medical University of Vienna
Type 2 Diabetes, Vitamin B12 Deficiency
Effect of Vitamin B12 Supplementation on Glycaemic Control in Uncontrolled Hyperhomocysteinemic Type 2 Diabetic Patients
Increased plasma homocysteine level is associated with macroangiopathy and nephropathy in type 2 diabetes. Also increased levels of serum homocysteine are associated with microalbuminuria which is associated with increased…
- Conditions
- Type 2 Diabetes, Vitamin B12 Deficiency, Hyperhomocysteinemia
- Trial name
- NCT02540642
- Testing
- METHYLCOBALAMIN 500 micrograms
- Where
- India
- Volunteers
- 38 people
- Sponsor
- Smt. Kashibai Navale Medical College and General Hospital
Muscle Strength, Vitamin B 12 Deficiency
Study of the Association of Muscle Strength, Balance and Other Factors With Vitamin Levels Among Elderly Diabetics
Vitamin B12 deficiency can cause severe problems with the blood, nerves, brain and psychological well-being. Ironically, our modern methods for the control of diabetes mellitus can actually contribute to vitamin B12 deficiency.
- Conditions
- Muscle Strength, Vitamin B 12 Deficiency, Folate Deficiency, Vitamin D Deficiency
- Trial name
- NCT03376490
- Where
- Singapore
- Volunteers
- 56 people
- Sponsor
- SingHealth Polyclinics
Vitamin B 12 Deficiency
Oral/Intramuscular B12 to Treat Cobalamin Deficiency
Objective: To determine the effectiveness of oral versus intramuscular Cobalamin (vitamin B12) by restore cobalamin parameter in blood at 8, 26 and 52 weeks in ≥ 65 aged patients with Cobalamin Deficiency.
- Trial name
- OB12 (NCT01476007)
- Testing
- oral Cobalamin (vitamin B12), intramuscular Cobalamin (vitamin B12)
- Where
- Spain
- Volunteers
- 284 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Mild Cognitive Impairment, Dementia
COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE
This retrospective study is a more extensive, confirmatory analysis of the cognitive and functional outcomes initially seen in 2 groups of MCI/dementia patients in Springfield, MA and compares specialized dementia care and a…
- Conditions
- Mild Cognitive Impairment, Dementia, Hypoxia, Hyperhomocysteinemia
- Trial name
- NCT02860338
- Volunteers
- 900 people
- Sponsor
- Clionsky Neuro Systems Inc.
Vitamin B 12 Deficiency
Vitamin B12 Acceptance and Biomarker Response Study
In this study, biomarker response after supplementation with oral and intramuscular vitamin B12 will be compared in a randomized clinical trial.
- Trial name
- NCT01832129
- Testing
- Oral administration of vitamin B12, i.m. injection of vitamin B12
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- University Hospital, Basel, Switzerland
Type 2 Diabetes, Vitamin B12 Deficiency
Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin
The purpose of this project is to compare two pharmacist-led population management strategies designed to increase the rate of appropriate monitoring of vitamin B12 and serum creatinine for patients taking metformin.
- Conditions
- Type 2 Diabetes, Vitamin B12 Deficiency, Neuropathy, Anemia
- Trial name
- NCT02076347
- Testing
- Office visit intervention, Electronic Message Intervention
- Where
- United States
- Volunteers
- 489 people
- Sponsor
- Ohio State University
Vitamin B 12 Deficiency
Cobalamin Supplementation During Infancy; Effect on B-vitamin Status, Growth and Psychomotor Development
Adequate levels of vitamin B12 (cobalamin) is necessary for normal growth and development in infants. We have earlier investigated cobalamin status in healthy children and we observed metabolic evidence of impaired cobalamin…
- Trial name
- NCT00479479
- Testing
- Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
- Where
- Norway
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Vitamin B12 Deficiency
Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients
A review of the literature reveals that very few studies have assessed the potential co-existence of vitamin B12 deficiency due to gastric parietal cell autoantibodies. While Segal et al.
- Trial name
- NCT01876329
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Keesler Air Force Base Medical Center
Vitamin B12 Deficiency
Vitamin B12 Supplementation Study
We hope to learn the clinical and functional signs of sub-clinical vitamin B12 deficiency and its response to supplementation in non-anemic, non-pregnant, and non-lactating women in Rural Mexico.
- Trial name
- NCT00826657
- Testing
- Vitamin B12
- Where
- Mexico
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Vitamin B12 Deficiency
Impact of Vitamin B12 Replacement on Epogen Dosing and Improvement of Quality of Life in Hemodialysis Patients
Vitamin B12 has several important functions in the body, two of which are production of red blood cells and the maintenance of a healthy nervous system. When vitamin B12 is deficient, abnormal red blood cells form.
- Trial name
- NCT01876732
- Testing
- Vitamin B12
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Northwell Health
Vitamin B12 Deficiency
Supplementary Vitamin B12 Effects on Elevated Homocysteine Levels of Vegetarians - Clinical Trial
Vegetarians are known to be deficient in vitamin B12, due to a lack or absence of dietary animal produce, which can elevate homocysteine.
- Trial name
- NCT01661309
- Testing
- Inactive lozenge, Methylcobalamin
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of West London