Clinical trials: Vitamin C
Healthy Subject, Immunity
The Effect of the Consumption of 4 Botanical Extracts on Immunity in Healthy Adults (B-4-Immune)
This study will evaluate the capacity of botanical extracts to modulate immune mechanisms compared to a placebo group in healthy volunteers.
- Trial name
- B-4-Immune (NCT05117385)
- Testing
- Botanical extract
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Variant Angina
ANti-Oxidant in Variant Angina (ANOVA) Trial
Purpose Objectives 1. To evaluate the anti-oxidant effect of long-term Vitamin C+E therapy on coronary vasospasm improvement. 2. To evaluate the anti-oxidant effect of long-term statin therapy on coronary vasospasm improvement.
- Trial name
- NCT03228238
- Testing
- Vitamin C and Vitamin E, Statin, Standard medication for variant angina
- Where
- South Korea
- Volunteers
- 320 people
- Sponsor
- Seoul National University Hospital
Cancer
Study of High-Dose Intravenous (IV) Vitamin C Treatment in Patients With Solid Tumors
The primary purpose of this study is to evaluate the safety and tolerability of vitamin C (ascorbic acid) given by injection into the vein.
- Trial name
- NCT00441207
- Testing
- Ascorbic Acid
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Midwestern Regional Medical Center
Fatigue
Efficacy of Vitamin C Injection on Fatigue in Workers After Work
Fatigue is one of the most frequently observed symptoms for company workers, and oxidative stress is regarded as one of its cause.
- Trial name
- NCT00633581
- Testing
- Ascorbic acid (Vitamin C), Normal saline
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- DongGuk University
Coronary Artery Disease
Evaluation of an Ayurvedic Herbal Compound Compared to Vitamins C+E and Placebo on Vascular Function in High-Risk Subjects
This was a randomized controlled trial aimed to evaluate the effects of an herbal Ayurvedic herbal supplement in comparison to a Vitamin C/E supplement and an inert placebo on heart health.
- Trial name
- NCT07206901
- Testing
- Maharishi Amrit Kalash, vitamin C + E
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Maharishi International University
Dry Eye Syndromes
Treatment of Dry Eye With Supplements
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response on the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01364311
- Testing
- Vitamac® Tag and Nacht capsules
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Photoaging
The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging
Our study involves the evaluation of a high potency peel in its efficacy for skin rejuvenation in the treatment of photoaging. This chemical peel regime is a high potency peel 70% glycolic acid combined with vitamin C that is…
- Trial name
- NCT02126644
- Testing
- 70% glycolic acid
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Distal Radius Fracture, Vitamine c
Vitamin c Supplementation in the Prevention of CRPS Following Distal Radius Fractures
Complex Regional Pain Syndrome type 1 is a pain syndrome that develops after a trauma, surgery, or idiopathically. The incidence after distal radius varies significantly in the literature.
- Conditions
- Distal Radius Fracture, Vitamine c, Prophylaxis
- Trial name
- NCT05842395
- Testing
- Vitamin C
- Where
- Syria
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Damascus University
Preterm Premature Rupture of Membranes
Does Vitamins C and E Supplementation of After Preterm Rupture of Membranes Prolong the Duration of Latency? A Prospective Randomized Controlled Study
Preterm premature rupture of membranes (PPROM) is a complication affecting 3-4.5% of all pregnancies. PPROM is the main known cause of preterm delivery and is associated worldwide with increased rates of neonatal and maternal…
- Trial name
- NCT01266928
- Testing
- vitamine C and E
- Where
- Turkey (Türkiye)
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Osteopenia or Osteoporosis
Effect of Consumption of Supplements and Enriched Olive Paste on Bone Metabolism Indices
It was a prospective randomized controlled trial. A sample of 115 apparently healthy post-menopausal women(45 -75 years of age) randomized into four groups and received supplements of Ca, Vitamin D and Mg with or without enriched…
- Trial name
- Osteoporosis (NCT06135831)
- Testing
- Functional olive paste, Calciovitmag (CDCaMg), Phosporovitmag (PDCaMg)
- Where
- Greece
- Volunteers
- 115 people
- Sponsor
- University of the Aegean
Myelodysplastic Syndromes and Leukemia, Myeloid, Acute
Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic Syndromes and Acute Myeloid Leukemia
This study is designed to test the combination of decitabine, arsenic trioxide and ascorbic acid in patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia
- Trial name
- NCT00671697
- Testing
- Arsenic Trioxide, Decitabine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Colonoscopy
Comparison Between OSS and 2L PEG/Asc for Bowel Preparation of Elderly People
For evaluation of the usefulness of oral sulfate solution (OSS) for bowel preparation of elderly people, investigators compare the efficacy, tolerability and safety between OSS and 2L polyethylene glycol (PEG) with ascorbic acid…
- Trial name
- NCT03520361
- Testing
- Oral sulfate solution (OSS), 2L PEG/Asc
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- KangWon National University Hospital
Thin Gingival Biotype
Comparative Evaluation of Vitamin C and Injectable-platelet Rich Fibrin in the Management of Thin Gingival Phenotype
The goal is to compare between the effect of vitamin C and Injectable-platelet rich fibrin in the management of thin gingival phenotype.
- Trial name
- NCT05841303
- Testing
- Vit C, injectable PRF
- Where
- Egypt
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cairo University
Atrial Fibrillation
Vitamin C and Atrial Fibrillation After Cardiac Surgery
The purpose of this study is to determine if vitamin C decreases the chance of developing atrial fibrillation, a type of arrhythmia or irregular heartbeat, following cardiac surgery.
- Trial name
- NCT01580683
- Testing
- Ascorbic Acid
- Where
- United States
- Sponsor
- Regional Hospital of Scranton
Contrast-induced Nephropathy, Statin
Effects Of Combination Therapy Of Statin And Ascorbic Acid For Prevention Of Contrast-Induced Nephropathy
To evaluate the benefit for statin use in prevention of of CI-AKI after computed tomography urogram (CTU).
- Conditions
- Contrast-induced Nephropathy, Statin, Ascorbic Acid, AKI
- Trial name
- NCT03391830
- Testing
- Atorvastatin-Ascorbic acid
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Mansoura University
Ocular Physiology, Regional Blood Flow
Effects of Vitamin C on Hyperoxia-Induced Reduction of Retinal Blood Flow
High arterial blood oxygen tension leads to vasoconstriction of retinal vessels, possibly related to an interaction between reactive oxygen species and endothelium-derived vasoactive factors.
- Trial name
- NCT00712907
- Testing
- vitamin C (Mayrhofer) 24mg/min i.v. for 64 min, 100% O2 (AGA) two times for 12 min
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Rotator Cuff Tear
Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair
1. Treatment of rotator cuff tear The rotator cuff tear is the most demanding part of the shoulder surgery. Rotator cuff degeneration is thought to be the largest cause of rotator cuff tear.
- Trial name
- VITCRCR (NCT02992028)
- Testing
- Intravenous Nutrition (Vitamins) injection, Intravenous Saline injection
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Himchan Hospital
Bowel Preparation, Colonoscopy
Bowel Preparation for Colonoscopy in the Elderly
The success of colonoscopy is closely related to the quality of colonic preparation. However, data regarding colonoscopy preparations in the elderly (65 years older) are scarce.
- Trial name
- NCT02290093
- Testing
- Standard full-volume PEG, Split-dose full-volume PEG, Split-dose low-volume PEG
- Where
- 3 sites in South Korea
- Volunteers
- 230 people
- Sponsor
- Kyunghee University Medical Center
Septic Shock
Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock
Preliminary studies show that giving a "cocktail" of intravenous vitamin C, vitamin B1, and steroids to critically ill patients with septic shock may dramatically improve mortality in those patients.
- Trial name
- NCT03828929
- Testing
- Vitamin C, Normal saline
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
COPD (Chronic Obstructive Pulmonary Disease)
Vitamin C's Antioxidant Effects and COPD Prognosis
This multicenter, randomized, double-blind, placebo-controlled clinical trial aims to evaluate the efficacy of Vitamin C supplementation in improving the prognosis of patients with Chronic Obstructive Pulmonary Disease (COPD)…
- Trial name
- NCT06664957
- Testing
- Vitamin C (Ascorbic Acid)
- Volunteers
- 650 people
- Sponsor
- Ningbo No. 1 Hospital