Clinical trials: Vitamin D Deficiency
Hypophosphatemia, Familial, Hyperparathyroidism
Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic Rickets
The purpose of this study is to determine the effectiveness of paricalcitol, a form of synthetic vitamin D, in lowering parathyroid hormone (PTH) levels and reducing disease symptoms in children and adults with X-linked…
- Trial name
- NCT00417612
- Testing
- Paricalcitol
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Yale University
Hypophosphatasia (HPP)
Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)
The purpose of this study is to characterize the natural history of HPP in patients with Juvenile-onset HPP.
- Trial name
- NCT02104219
- Where
- 19 sites in United States, Australia and 6 more
- Volunteers
- 32 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Obesity, Vitamin D Deficiency
Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients
As the use of bariatric surgery for treatment of extreme obesity adults continues to rise, clinicians must be aware of pre-existing nutritional deficiencies in overweight and obese patients.
- Trial name
- NCT01385098
- Testing
- Vitamin D3 and Calcium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Vadim Sherman, MD
Systemic Lupus Erythematosus, SLE
Vitamin D3 in Systemic Lupus Erythematosus
The purpose of this study is to explore the impact of vitamin D3 on the expression of alpha interferon (IFN alpha) expression in systemic lupus erythematosus (SLE) patients with vitamin D deficiency.
- Conditions
- Systemic Lupus Erythematosus, SLE, Lupus
- Trial name
- NCT00710021
- Testing
- Vitamin D3
- Where
- 8 sites in United States
- Volunteers
- 57 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hypophosphatasia
Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)
This clinical trial was conducted to study hypophosphatasia (HPP), a bone disorder caused by gene mutations or changes. These gene mutations cause low levels of an enzyme needed to harden bone.
- Trial name
- NCT01163149
- Testing
- asfotase alfa
- Where
- 3 sites in United States, Canada
- Volunteers
- 19 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Secondary Hyperparathyroidism
Suspected Deficient Activation of Vitamin D in Patients With Secondary Hyperparathyroidism
The purpose of this study is to determine if a reduction in the enzyme 1-hydroxylase, which activates Vitamin D, is the cause of overactivity of the parathyroid glands (called secondary hyperparathyroidism - normal blood calcium…
- Trial name
- 1hydroxylase (NCT00754442)
- Testing
- Teriparatide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Nephrolithiasis, Urolithiasis
Vitamin D Repletion in Stone Formers With Hypercalciuria
Vitamin D plays a critical role in maintaining bone health, as well as preventing cardiovascular disease, cancer, and various autoimmune diseases, such as diabetes.
- Conditions
- Nephrolithiasis, Urolithiasis, Idiopathic Hypercalciuria, Vitamin D Deficiency
- Trial name
- NCT01295879
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York Presbyterian Hospital
Hemodialysis Patients, Vitamin D Insufficiency
Effect of Omega-3 Fatty Acid on Vitamin D Activation
Extra-renal sources of 1, 25-dihydroxyvitamin D can be increased to normal serum 1, 25-dihydroxyvitamin D levels in chronic kidney disease patients after administration of high dose 25-hydroxyvitamin D.
- Conditions
- Hemodialysis Patients, Vitamin D Insufficiency, Vitamin D Deficiency
- Trial name
- NCT01596842
- Testing
- Omega-3 fatty acid ethylester 90, Olive oil, cholecalciferol
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Dong-A University
Arterial Dysfunction, Chronic Kidney Disease
Vitamin D and Arterial Function in Patients With Chronic Kidney Disease
The purpose of this study is to determine whether nutritional (cholecalciferol) or active vitamin D (calcitriol) supplementation improves vascular endothelial function in patients with stage IIIB and IV chronic kidney disease…
- Trial name
- NCT01384539
- Testing
- Cholecalciferol, Calcitriol
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Colorado, Denver
Vitamin D Deficiency
Effect of Vitamin D3 on Vascular Function
Vitamin D is a natural nutrient. A little comes from our normal daily diet. Most of it comes from our skin after we have been in sunlight. If we have darker skin, we make less vitamin D.
- Trial name
- NCT00948298
- Testing
- Vitamin D
- Volunteers
- 130 people
- Sponsor
- Charles Drew University of Medicine and Science
Calcium and Vitamin D Deficiencies
Calcichew D3 Preference Study in Participants Eligible for Calcium and Vitamin D Supplementation.
The purpose of this study is to compare the preference of Calcichew D3 500/400 (containing 500 mg calcium and 400 IU of vitamin D) with Adcal-D3 600/400 (containing 600 mg of calcium and 400 IU of vitamin D) in Test Group 1, and…
- Trial name
- NCT02457247
- Testing
- Calcichew D3, Adcal-D3, Kalcipos-D
- Where
- 9 sites in Germany, United Kingdom
- Volunteers
- 276 people
- Sponsor
- Takeda
Vitamin D3 Deficiency
Preventing Health Disparities During Pregnancy Through Vitamin D Supplementation
The purpose of this study is to give all mothers the best chance for a healthy pregnancy through vitamin D supplementation. We will study women of diverse racial/ethnic backgrounds who will receive either the current vitamin D…
- Trial name
- NCT01932788
- Testing
- Vitamin D3 4000 IU in gummy form
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Polycystic Ovarian Syndrome, Vitamin D Deficiency
Health Benefits of Vitamin D and Calcium in Women With PCOS (Polycystic Ovarian Syndrome)
The investigators conducted a prospective un-blinded pilot study of Vitamin D plus Calcium (Ca) supplementation in overweight (BMI > 27) premenopausal women diagnosed with Polycystic Ovarian Syndrome (PCOS), as defined by the…
- Trial name
- NCT00743574
- Testing
- Vitamin D2 (Ergocalciferol), Medroxyprogesterone (Provera), Vitamin D3 (Cholecalciferol)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Yale University
Healthy
Defining Vitamin D Insufficiency in School Age Children: A Randomized Placebo Controlled Trial of Vitamin D3
The study objective is to characterize the threshold levels of serum 25-hydroxyvitamin D for the definition of vitamin D insufficiency in 8-14 year old African American and Caucasian children.
- Trial name
- Vitamin D RCT (NCT00732758)
- Testing
- Vitamin D3 1000 IU
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Frail Elderly, Vitamin d Deficiency
Vitamin D in Vulnerable Adults (VIVA-VA)
Vitamin D insufficiency is a problem of growing concern, given its prevalence in older persons and the association of low vitamin D with multiple major health problems, including mobility and balance deterioration and falls…
- Trial name
- VIVA-VA (NCT01170273)
- Testing
- vitamin D
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Human Immunodeficiency Virus (HIV)
Vitamin D3 Supplementation in Patients With HIV: Effects on Interleukin-6 Levels and CD4 Counts
This study aims to evaluate the effect of Vitamin D3 supplementation on inflammatory markers and immune status in patients with HIV who are receiving antiretroviral therapy.
- Trial name
- NCT07553052
- Testing
- Vitamin D3, Antiretroviral (ARV) medications
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Sebelas Maret
Hip Fracture, Vitamin D Deficiency
Vitamin D Levels in Frail Elderly Patients With a Hip Fracture
The purpose of this study is to assess whether all frail elderly admitted with hip fracture has a vitamin D deficiency, and if s-25(OH)D deficiency increases the risk of hip fracture in frail elderly.
- Trial name
- NCT01816711
- Where
- Denmark
- Volunteers
- 447 people
- Sponsor
- University of Aarhus
Vitamin D Deficiency
Establishing the Vitamin D Requirements During Lactation
The purpose of this study is to determine the effectiveness and safety of maternal and infant vitamin D supplementation as a function of ethnicity and latitude in the prevention of vitamin D deficiency in the breastfeeding…
- Trial name
- NCT00412074
- Testing
- 400 IU Vitamin D3 (cholecalciferol), 2400 IU Vitamin D3 (cholecalciferol), 6400 IU Vitamin D3 (cholecalciferol)
- Where
- 2 sites in United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Myopathic Symptoms
Is Treatment of Vitamin D Deficiency Associated With Resolution of Statin-Induced Muscular Symptoms
Statins are a class of drugs that are highly effective at lowering cholesterol levels. However, compliance is often limited by symptoms of muscle pain.
- Trial name
- NCT01568255
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Rheumatoid Arthritis, Vitamin D Deficiency
Treatment of Vitamin D Deficiency in Patients With Rheumatoid Arthritis
The purpose of this study is to investigate the effect of vitamin D repletion on disease activity and disability in patients with rheumatoid arthritis.
- Trial name
- NCT01426347
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Johns Hopkins University