Clinical trials: Vitamin Deficiencies
Endothelial Dysfunction, Hyperhomocysteinemia
Effect of L-Arginine and Pycnogenol on Light to Moderate Hypertension and Endothelial Function
The effect of a combination product (Verum ) with L-arginine, Pycnogenol, vitamin K2, R-(+)-alpha-lipoic acid and vitamins B6, B12 and folic acid is investigated in a double blind placebo-controlled cross-over study.
- Conditions
- Endothelial Dysfunction, Hyperhomocysteinemia, Hypertension Grade I, Subgroup "Borderline" (WHO)
- Trial name
- NCT02392767
- Testing
- Verum
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dr. Loges & Co. GmbH
Healthy, Obesity
Open Label Randomized Clinical Study to Promote a Healthy Lifestyle in Medical Students
The main medical and social purpose of the project "It's trendy to be healthy!" is the promotion of healthy lifestyles and healthy eating among student youth.
- Conditions
- Healthy, Obesity, Nutrition, Healthy, Vitamin D Deficiency
- Trial name
- NCT05073029
- Testing
- nutrition program and modification of physical activity, synbiotic (Fructooligosaccharides+Lactobacillus rhamnosus GG ATCC 53103, 4.0х109 colony forming units - CFU), vitamin D3
- Where
- 2 sites in Ukraine
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bogomolets National Medical University
Vitamin B12 Deficiency
Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients
A review of the literature reveals that very few studies have assessed the potential co-existence of vitamin B12 deficiency due to gastric parietal cell autoantibodies. While Segal et al.
- Trial name
- NCT01876329
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Keesler Air Force Base Medical Center
Neural Tube Defects, Folic Acid Deficiency
Feasibility, Acceptability and Directional Signal Effect on Blood Folate Levels of Iodized Salt Fortified With Folic Acid: Clinical Study
Aim 1: Assess directional signal of effect of fortified salt with folic acid and iodine on blood serum folate levels. It will be accomplished by feasibility pre-test/post-test clinical study by estimating mean and variability of…
- Conditions
- Neural Tube Defects, Folic Acid Deficiency, Fortification
- Trial name
- FASALT (NCT05935631)
- Testing
- Salt with folic acid and iodine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Vitamin D Deficiency
Effects of Antarctic Environment on Vitamin D Status and Health Risk Biomarkers of Its Inhabitants
The purpose of this study is to evaluate vitamin D (VD) deficiency in the population of Chilean Antarctica and evaluate the efficacy and safety of VD supplementation to decrease VD deficiency and favorably influence biomarkers…
- Trial name
- AntarD (NCT02930434)
- Testing
- cholecalciferol
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Anemia, Nutritional Deficiency
Anemia in Older Adults
A cross-sectional study with 829 older Mexican adults were recruited from July to September 2015, from four localities in the southern region of México.
- Conditions
- Anemia, Nutritional Deficiency, Inflammation
- Trial name
- NCT04820465
- Testing
- Non available due to cross-sectional study design
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Vitamin D Deficiency, Chemotherapy Effect
Vitamin D Can Increase Pathological Response of the Breast Cancer Patients Treated With Neoadjuvant Therapy
The aim of the study is to evaluate the relationship between the vitamin D replacement and pathological response in patients undergoing neoadjuvant therapy according to different molecular sub types.
- Conditions
- Vitamin D Deficiency, Chemotherapy Effect, Pathology
- Trial name
- NCT03986268
- Testing
- Vit D
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Florence Nightingale Hospital, Istanbul
Vitamin D Deficiency
Isolation of Vitamin D Binding Protein Isoforms From Human Volunteers
The purpose of this study is to isolate genotype-specific DBP/Gc from homozygous human volunteers and use these purified proteins to cross-validate existing or novel assays for this serum protein and to evaluate the binding…
- Trial name
- NCT02258035
- Testing
- Blood draw
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Vitamin D Deficiency
OASIS Study: Vitamin D Deficiency Prevention Among Older Adults in Ireland
Vitamin D deficiency is common. It is caused by limited sun availability together with a low supply of vitamin D in the food system. There is a high prevalence of low vitamin D status around the world.
- Trial name
- OASIS (NCT06705582)
- Testing
- Fortified Bread, Unfortified bread
- Where
- 2 sites in Ireland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University College Cork
Hypovitaminosis, Vitamin A Deficiency
Impact of Maternal Supplementation With Dual Megadose of Vitamin A
The purpose of this study is to evaluate the effect of maternal supplementation with 400,000 IU of oral retinol palmitate in the post-partum, the nutritional situation of the binomial mother-child, on growth and morbidity of…
- Trial name
- NCT00742937
- Testing
- vitamin A
- Where
- Brazil
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Vitamin C Deficiency
"Novo C Plus" Vitamin C Containing Dietary Supplement Bioavailability in Healthy Subjects
The aim of this study is to evaluate the bioavailability of "Novo C Plus" vitamin C containing dietary supplement compared to licensed vitamin C medications. The novelty of this product is the liposomal formulation.
- Trial name
- NCT02606773
- Testing
- Ascorbic Acid
- Where
- Hungary
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Vitamin A Deficiency
Efficacy of Yellow Cassava to Improve Vitamin A Status of Kenyan School Children
The overall aim of the project is to provide proof-of-principle that biofortification of cassava with vitamin A is a viable strategy to improve vitamin A status of deficient populations.
- Trial name
- CASSAVITA (NCT01614483)
- Testing
- Yellow cassava, White cassava
- Where
- Kenya
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Iron Overload, Oxidative Stress
Effects of Taking Prenatal Vitamin-mineral Supplements During Lactation on Iron Status and Markers of Oxidation
Most breastfeeding women are told by their health care provider to continue taking prenatal vitamins after they give birth. A woman's requirement for iron while breastfeeding is low, yet prenatal vitamins contain a large amount…
- Conditions
- Iron Overload, Oxidative Stress, Iron-deficiency Anemia
- Trial name
- NCT01047098
- Testing
- Iron
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Vitamin D Deficiency, Osseointegration Failure of Dental Implant
Vitamin-D Insufficiency and Implants
Vitamin D is important for bone health, immune function, and inflammation, along with dental implant success. The study aimed to assess bone markers and cytokine levels in patients with and without vitamin D insufficiency to…
- Conditions
- Vitamin D Deficiency, Osseointegration Failure of Dental Implant, Peri-Implantitis
- Trial name
- NCT06452251
- Testing
- OPG, OC, RANKL, IL-10, IL-1β, Ca, TNF-α and Caspase-1 ELISA, Resonance Frequency Analysis, Periodontal clinical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vesile Elif Toy
Vitamin D Deficiency, 25-Hydroxyvitamin D3 Deficiency, Selective
Effect of Vitamin D3 Supplementation in Children From 12 to 30 Months of Age.
Background Vitamin D (VD) is essential for calcium absorption, bone health and growth in children. In a national representative sample authors found mean serum concentration of 25-Hydroxi-Vitamin-D (25-OH-D) of 59 nmol/L, in…
- Trial name
- NCT03544671
- Testing
- Vitamin D
- Where
- Mexico
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Vitamin D Deficiency, Vitamin D Insufficiency
ALPCO 25(OH) Vitamin D CLIA Kit - Fresh Versus Frozen Serum and Plasma Stability Study
This study evaluates the stability of 25-hydroxyvitamin D [25(OH)D] measurements in human serum and plasma using the ALPCO 25(OH) Vitamin D CLIA Kit.
- Conditions
- Vitamin D Deficiency, Vitamin D Insufficiency, Healthy Volunteers
- Trial name
- NCT07565064
- Testing
- ALPCO 25(OH) Vitamin D CLIA Kit
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American Laboratory Products Company
Diabetes Type 2, Diabetic Neuropathies
High vs Low Dose Vitamin D in Patients With Diabetic Peripheral Neuropathy
Aim. To assess the effect of different doses of vitamin D supplementation on peripheral neuropathy in patients with type 2 diabetes mellitus (T2DM).
- Conditions
- Diabetes Type 2, Diabetic Neuropathies, Vitamin D Deficiency
- Trial name
- NCT04377399
- Testing
- Vitamin D
- Where
- Russia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Iron Deficiency, Vitamin A Deficiency
Nutritional Status and Bouillon Use in Northern Ghana
This pilot aims to generate data that are critical for informing the design of a planned, more detailed study to evaluate the effect of multiple micronutrient (MN)-fortified bouillon cube on biomarkers of nutrient status of women…
- Conditions
- Iron Deficiency, Vitamin A Deficiency, Vitamin B 12 Deficiency, Folate Deficiency
- Trial name
- NCT04632771
- Testing
- N/A (observational study)
- Where
- Ghana
- Volunteers
- 995 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hyperhomocysteinemia
Effects of Low-dose Complex B-vitamins on Homocysteine and Framingham Risk Score Among Chinese Elderly
The purpose of this study is to evaluate whether low dose complex B-vitamins (folic acid,vitamin B6 and vitamin B12) can lower the risk of developing hyperhomocysteinemia in an apparently healthy population with low folate/B12…
- Trial name
- NCT00755664
- Testing
- Low-dose complex B-vitamins
- Where
- China
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Peking University
Mortality Through Six Months of Age, Vitamin A Deficiency
Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh
The purpose of this trial is determine whether a 50,000 IU oral dose of vitamin A delivered to newborn infants within the first days of life, reduces six-month infant mortality by at least 15%.
- Trial name
- NCT00128557
- Testing
- vitamin A supplementation (15,000 ug retinol equivalents or 50,000 IU)
- Where
- Bangladesh
- Volunteers
- 15,937 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health