Clinical trials: Vitamin Deficiencies
Vitamin D Deficiency Defined as Serum 25OHD < 75 Nmol/l or 30ng/ml, Preeclampsia
Vitamin D and Preeclampsia
Hypothesis : Vitamin D serum concentration is decreased in the first trimester in pregnant women who will develop preeclampsia in the second or third trimester compare to a control group Primary purpose : To determine the vitamin…
- Conditions
- Vitamin D Deficiency Defined as Serum 25OHD < 75 Nmol/l or 30ng/ml, Preeclampsia, Neonatal Hypercalcemia, Pregnancy
- Trial name
- FEPED (NCT01648842)
- Where
- France
- Volunteers
- 3,173 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Insufficiency,Chronic, Dietary Intake Patterns
Strategies for Proactive Health in People With Kidney Function Decline
This prospective cohort study aims to investigate how kidney function decline affects multiple body systems and how personalized nutrition can help maintain health and slow disease progression.
- Conditions
- Renal Insufficiency,Chronic, Dietary Intake Patterns, Malnutrition, Frailty
- Trial name
- NCT07245186
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Huashan Hospital
Obesity, Childhood
Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents
Childhood obesity is one of the most serious public health challenges of the 21st century, with an increasing prevalence over time in developed countries.
- Trial name
- OBEVIDOS (NCT03516968)
- Testing
- Monthly bolus of cholecalciferol per os, Daily dose of cholecalciferol per os
- Where
- 4 sites in France
- Volunteers
- 68 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Disease, End Stage Renal Disease
Vitamin D Effect on Calcium Absorption on Persons on Hemodialysis
The assumption has been that 1,25(OH)2D is solely responsible for calcium absorption. That has been one of the presumed causes of hyperparathyroidism in chronic kidney disease (CKD) (low 1,25(OH)2D leads to decreased calcium…
- Conditions
- Chronic Kidney Disease, End Stage Renal Disease, Vitamin D Deficiency
- Trial name
- NEPH-Cal-D (NCT01325610)
- Testing
- cholecalciferol
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Creighton University
Chronic Renal Insufficiency, Renal Osteodystrophy
Clinical Observation on Bone Metabolism Induced by Chronic Renal Insufficiency
Patients with chronic renal insufficiency usually develop secondary osteoporosis or bone loss, which is called renal osteodystrophy.
- Trial name
- NCT02147782
- Where
- 4 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
X-Linked Hypophosphataemia
A UK Multicentre, Health-Related Quality of Life Study for Children and Adolescents With XLH
This study aims to provide Health-related Quality of Life (HRQoL) data from children and adolescents with growing skeletons in the United Kingdom (UK), including those treated with burosumab or alternative XLH treatment, as part…
- Trial name
- NCT04819490
- Where
- 6 sites in United Kingdom
- Volunteers
- 32 people
- Sponsor
- Kyowa Kirin Pharmaceutical Development Ltd
Vitamin d Deficiency, COVID-19
Risk in Devel Long-COVID in Contracting SARS-CoV-2 Infection After COVID-19 Vaccination in Relation to Vitamin D3 Suppl
The aim of this observational retrospective study is to evaluate the effect of supplementation with cholecalciferol D3 in reducing the risk of: occurence of Long COVID syndrome after acute COVID-19 illness occurence of SARS-CoV-2…
- Conditions
- Vitamin d Deficiency, COVID-19, Long COVID
- Trial name
- LONGVITAVAX2 (NCT06452082)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele
Chronic Kidney Disease, Hyperparathyroidism, Secondary
Safety and Efficacy of CTAP101 to Treat Secondary Hyperparathyroidism in Stage 3 or 4 CKD and Vitamin D Insufficiency
This study will evaluate the efficacy of CTAP101 Capsules versus placebo in reducing intact parathyroid hormone (iPTH) by at least 30% from pretreatment baseline; safety and tolerability of CTAP101 will also be evaluated
- Conditions
- Chronic Kidney Disease, Hyperparathyroidism, Secondary, Vitamin D Deficiency
- Trial name
- NCT01704079
- Testing
- CTAP101 30 μg capsules, Sugar pill to CTAP101 30 μg capsules
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- OPKO IP Holdings II, Inc.
Rickets
Study to Assess the Use of a Simple Lab Test to Screen for Rickets in Children
Some experts recommend that all breastfed babies receive supplemental vitamin D. The purpose of this study is to determine the rate of vitamin D use in breastfed babies, the recommendations of pediatricians regarding vitamin D…
- Trial name
- NCT00502866
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Vitamin D Deficiency
Vitamin D During Pregnancy
Vitamin D insufficiency is common globally. Pregnant women, who need an increased supply of this vitamin for the proper development of the fetus, are a significant risk group.
- Trial name
- NCT01589783
- Testing
- completion of a questionnaire, Blood draw
- Where
- Israel
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Heart Failure, Reduced Ejection Fraction, Vitamin B12 Deficiency
Heart Failure With Reduced Ejection Fraction: Adjuvant Therapy With Neurostimulation and Chlorella Pyrenoidosa (HD-tDCS)
Reduced ejection fraction heart failure (HFrEF) is a complex and multifactorial condition. It is characterized by a decrease in the ability of the left ventricle to eject blood effectively during systole, resulting in an ejection…
- Trial name
- HD-tDCS (NCT06528366)
- Testing
- Chlorella pyrenoidosa, High Definition Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Paraíba
Vitamin D Deficiency
Clinical Comparative Evaluation of the Use of Photodynamic Therapy in Conjunction With the Use of Vitamin D in Management Stage II Grade B Periodontitis Patients
Clinical Comparative Evaluation of the use of Photodynamic Therapy in conjunction with the use of Vitamin D in management Stage II Grade B Periodontitis Patients: A Randomized controlled clinical trial.
- Trial name
- NCT06700122
- Testing
- non-surgical periodontal therapy (SRP) and Photodynamic therapy (PDT) with systemic vitamin D
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cystic Fibrosis, Vitamin D Deficiency
Vitamin D3 for the Treatment of Low Vitamin D in Cystic Fibrosis
Vitamin D deficiency is common in cystic fibrosis. Vitamin D deficiency frequently persists despite aggressive treatment with ergocalciferol, a vitamin D preparation also known as vitamin D2.
- Trial name
- NCT00762918
- Testing
- cholecalciferol
- Sponsor
- Children's Hospital of Philadelphia
Leiomyoma, Vitamin D Deficiency
Vitamin D Deficit in Women With Uterine Fibroids
Determinate the level of vitamin D in blood, and evaluate the prevalence of deficit and insufficiency among patients with diagnosis of uterine fibroids
- Conditions
- Leiomyoma, Vitamin D Deficiency, Fibroid Uterus
- Trial name
- NCT04030182
- Testing
- Level of Vitamin D
- Where
- 2 sites in Mexico
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Vitamin D Deficiency, Infection
Vitamin D Level and Risk of Infections in Cirrhotic Patients
It is widely known that vitamin D has an important role in calcium metabolism and bone mineralization. Its deficiency is related to rickets and osteomalacia in children and adults respectively.
- Conditions
- Vitamin D Deficiency, Infection, Liver Cirrhosis
- Trial name
- NCT03391245
- Testing
- 3- Serum 25-Hydroxy Vitamin D level will be measured by Competitive ELISA technique
- Where
- Egypt
- Volunteers
- 87 people
- Sponsor
- Assiut University
Vitamin D Deficiency
Vitamin D and Immunity: Photosynthesis Versus Supplementation
The optimal way to restore serum 25-hydroxyvitamin D sufficiency is currently debatable. UV irradiation through sunshine exposure promotes endogenous vitamin D synthesis, although this can also be associated with a risk of…
- Trial name
- IMMUNI-D (NCT03609970)
- Testing
- Vitamin D, UVR (Solar simulated radiation)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Hot Flushes, Menopause, Premature
The Role of Vitamin D in Menopause: Relationship to Menopausal Symptoms in Body Composition
Specific Aim 1: To compare effects of Vitamin D supplementation to usual care on symptoms in women transitioning to early postmenopause and determine the associated effect size in order to conduct a power analysis for a future…
- Conditions
- Hot Flushes, Menopause, Premature, Obesity, Vitamin D Deficiency
- Trial name
- FLASH (NCT01141972)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
X-Linked Hypophosphatemia
Efficacy and Safety of Burosumab Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With XLH
The primary objective of this study is to evaluate the effect of KRN23 (burosumab) therapy in improving rickets in children with XLH compared with active control (oral phosphate/active vitamin D).
- Trial name
- NCT02915705
- Testing
- burosumab, Oral Phosphate Supplement, active vitamin D
- Where
- 16 sites in United States, Australia and 5 more
- Volunteers
- 61 people
- Sponsor
- Kyowa Kirin, Inc.
Morbid Obesity, Vitamin D Deficiency
Effect of a Monthly High Dose of Vitamin D3 on Bariatric Surgery Patients
Bariatric surgery patients tend to have malabsorption of many micronutrients such as B12, Iron and vitamin D postoperative. So in this study, a monthly high dose of vitamin D3 is giving to patients with their routine supplements…
- Trial name
- NCT02477956
- Testing
- vitamin D3 (Replesta), vitamin D
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Texas Tech University
Non-alcoholic Fatty Liver Disease, Vitamin D Deficiency
Vitamin D in Fatty Liver Disease
This study evaluates the influence of vitamin D in reducing laboratory, elastographic (Fibroscan) and metabolic components of NAFLD. Half of the patients will receive vitamin D (Plivit D3) while the other half will receive placebo
- Trial name
- NCT04038853
- Testing
- 1,25-Dihydroxyvitamin D
- Volunteers
- 360 people
- Sponsor
- University Hospital Rijeka
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