Clinical trials: Vitamin E
Peyronie's Disease
Testosterone Pellets Plus Vitamin D and E Versus Vitamin D and E Alone for the Treatment of Peyronie's Disease
Two recent studies have identified low levels of serum testosterone in association with Peyronie's Disease (PD), with a significant correlation noted between severity of testosterone deficiency and severity of curvature.
- Trial name
- PD+ (NCT01578473)
- Testing
- Vitamin D2, Vitamin E, Testosterone Pellets
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Men's Health Boston
Inflammation, Oxidative Stress
Antioxidants Combined With Cryotherapy on Inflammatory Response After Resistance Exercise in Untrained Volunteers
Acutely resistance exercise induces inflammatory responses and leukocytosis arising of oxidative stress, that clinically manifested by pain and/or delayed onset muscle soreness (DOMS).
- Conditions
- Inflammation, Oxidative Stress, Pain
- Trial name
- NCT02902315
- Testing
- Cryotherapy, Vitamins C and E, Vitamins C and E associated with cryotherapy
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Noise-Induced Hearing Loss
Micronutrients to Prevent Noise-induced Hearing Loss
Noise-induced hearing loss (NIHL) is a significant clinical, social, and economic issue. Studies in animals have allowed us to identify mechanisms contributing to NIHL, including direct mechanical trauma, free radicals formed in…
- Trial name
- NCT00808470
- Testing
- beta-carotene, vitamins C and E, magnesium
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Skin Aging, Wrinkles
Astaxanthin (2 mg) + Lycopene (1.8 mg) + D-Alpha-Tocopherol (10 IU) For The Treatment Of Skin Aging
The purpose of this study is to determine the clinical efficacy of a combination of Astaxanthin (2 mg), Lycopene (1.8 mg), and d-alpha-Tocopherol (10 IU) in terms of its skin anti-aging properties.
- Trial name
- NCT03460860
- Testing
- Astaxanthin (2mg)+Lycopene (1.8mg)+D-Alpha-Tocopherol (10IU)
- Where
- Philippines
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- United Laboratories
Acne
Topical Palm Tocotrienols on Blemish-prone Skin
A single-center, double-blind, randomised, placebo-controlled parallel-group study. Selected subjects will be randomised into active and control groups in a ratio of 1:1.
- Trial name
- NCT05756881
- Testing
- Cosmetic product
- Where
- Malaysia
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Schizophrenia
Role of Antioxidants (Vitamin C and E) in the Management of Schizophrenia
Background: Antioxidants are substances that are considered as a defensive material which protects cells from destruction. It is evident that use of food stuff rich in antioxidant will fortify one's ability to encounter with…
- Trial name
- NCT04078048
- Testing
- Antioxidants (Vitamin C, E )
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Pityriasis Alba
Serum 25(OH) Vitamin D and Total Serum Immunoglobulin E Levels in Patients With Pityriasis Alba
Pityriasis alba (PA) is a common, benign skin disorder occurring predominantly in children and adolescents. It is characterized by ill-defined hypopigmented macules and patches, round or oval in shape.
- Trial name
- NCT03443765
- Testing
- Detection of Plasma levels of 25(OH) vitamin D by ELISA technique, Detection of Total serum immunoglobulin E by ELISA technique
- Where
- Uzbekistan
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan
Preeclampsia, Vitamin A Deficiency
The Correlation Between Vitamin A / E Levels and Preeclampsia
Vitamin A (VA) and vitamin E (VE) are fat-soluble vitamins and indispensable substances in life activities. VA plays an important role in visual function, normal formation and development of epithelial cells, development and…
- Conditions
- Preeclampsia, Vitamin A Deficiency, Vitamin E Deficiency
- Trial name
- NCT03971604
- Testing
- Vitamin A, Vitamin E
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Cancer
Processed Meat and Colon Carcinogenesis
Colorectal cancer kills forty five people in France every day. Epidemiological studies suggest that two cases out of three could be prevented and show that processed meat intake is a consistent risk factor.
- Trial name
- Hemcancer (NCT00994526)
- Testing
- Ham, Ham + calcium, Ham + vitamin E
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Healthy
Effect of Gamma Tocopherol Supplementation on Neutrophil Response to 20,000 EU of Clinical Center Reference Endotoxin in Normal Adults
The purpose of this research study is to learn whether high dose vitamin E (gamma tocopherol) will affect the way your body responds to an acute inflammation in your lungs.
- Trial name
- GammaTox (NCT00631085)
- Testing
- gamma tocopherol
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Preeclampsia, Eclampsia
RCT of Antioxidant Therapy to Prevent Preeclampsia in Brazil
The perinatal morbidity and mortality rates for Brazil are five to ten-fold higher than those reported for upper income countries.
- Conditions
- Preeclampsia, Eclampsia, HELLP Syndrome, Pregnancy
- Trial name
- NCT00097110
- Testing
- Vitamin C and E
- Where
- Brazil
- Volunteers
- 734 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Dry Socket
Role of Vitamin E in Reducing Dry Socket
90 female patients seeking extraction of a single tooth in the lower posterior region were divided randomly into 45 patients received vitamin E inside the socket after extraction (study group) and 45 patients didn't receive…
- Trial name
- NCT05984173
- Testing
- Vitamin E application
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Photoaging, Photodamage
Randomised Controlled Trial of an Antioxidant and Sunscreen Combination Cream for Reducing DNA Damage in Human Skin
This randomized, double-blind, vehicle-controlled clinical trial investigates whether daily use of an encapsulated SPF 50 formulation containing a multi-antioxidant complex provides greater mitochondrial DNA (mtDNA) protection in…
- Conditions
- Photoaging, Photodamage, Mitochondrial Damage, Sunscreen
- Trial name
- NCT07301515
- Testing
- Antioxidant + Sunscreen Cream
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Klira Skin
Preterm Premature Rupture of Membranes
Does Vitamins C and E Supplementation of After Preterm Rupture of Membranes Prolong the Duration of Latency? A Prospective Randomized Controlled Study
Preterm premature rupture of membranes (PPROM) is a complication affecting 3-4.5% of all pregnancies. PPROM is the main known cause of preterm delivery and is associated worldwide with increased rates of neonatal and maternal…
- Trial name
- NCT01266928
- Testing
- vitamine C and E
- Where
- Turkey (Türkiye)
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Vitamin D Deficiency, Hypovitaminosis A
A Randomized Controlled Trial Testing The Effect Of A Multi-Nutrient Fortified Juice
The goal of this investigator-initiated study is to determine whether the fortification of orange juice with vitamin D, vitamin A, and vitamin E will enhance the vitamin D, vitamin A, and vitamin E status children ages 6-10 that…
- Conditions
- Vitamin D Deficiency, Hypovitaminosis A, Vitamin E Deficiency
- Trial name
- NCT01909063
- Testing
- Vitamin D, Vitamin D, Vitamin E, and Vitamin A, Control, 700 mg Calcium
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Boston University
Biological Availability
Bioavailability of Carotenoids Present in Mamey Sapote (Pouteria Sapota (Jacq.) H. E. Moore & Stearn) Fruit
The goal of the study is to determine if mamey sapote fruit, rich in rare potentially provitamin A keto-carotenoids, is a good source of vitamin A in humans.
- Trial name
- NCT03873909
- Testing
- Fruit Smoothie, Matrix-Free Shake
- Where
- 2 sites in Costa Rica, Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Hyperlipidemia
Effect of Citrus Bioflavonoids/Vitamin E in Conjunction With Fish Oil Supplementation
The purpose of this 8-week intervention trial is to investigate the effect of a dietary supplement (containing citrus bioflavonoids and vitamin E) plus fish oil supplementation in healthy hyperlipidemic subjects
- Trial name
- NCT01671254
- Testing
- FishOil, CBE75, CBE150
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- MetaProteomics LLC
Infant, Newborn, Infant, Small for Gestational Age
Vitamin E for Extremely Preterm Infants
The purpose of this pilot trial is to test the safety and efficacy of administering one dose of vitamin E, via a tube into the stomach, to extremely preterm infants (less than 27 weeks gestation and less than 1000 grams birth…
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01193270
- Testing
- Vitamin E
- Where
- 16 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Arsenical Keratosis
Effect of Spirulina on Zinc, Vitamin E and Linoleic Acid Levels in Palm Skin Following Chronic Exposure to Arsenic
Patients of arsenical keratosis may be treated with spirulina. Is this improvement related to the levels of zinc, vitamin E and linoleic acid at the site of the keratosis (palm)? To understand this, patients of palmer arsenical…
- Trial name
- NCT01752972
- Testing
- Spirulina
- Where
- Bangladesh
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Biological Availability of Vitamins and Micronutrients
Effect of Genetic Variants on Fat-soluble Vitamin Bioavailability
The aim was to identify minor genetic variations (single nucleotide polymorphisms) that explain the interindividual variability in bioavailability of fat soluble micronutrients (fat soluble vitamins and carotenoids).
- Trial name
- VITAGENES (NCT02100774)
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement