Clinical trials: Vitamin E
Vitamin B12 Deficiency
A Study to See if a Combination of Vitamins That is Injected Into a Muscle is as Good and Safe as a Vitamin That is Taken by Mouth
Primary efficacy objective: To investigate the effects of a parenterally vitamin B12 combination treatment versus an oral vitamin B12 mono therapy on the vitamin B12 status in female and male patients as determined by the change…
- Trial name
- EASYVIT (NCT07029698)
- Testing
- Vitamin B12, Vitamin B6, Folic acid, Vitamin B12 (Cyanocobalamin)
- Where
- 2 sites in Ukraine
- Volunteers
- 46 people
- Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
Infant Vitamin K Status, Vitamin K Deficiency Bleeding
The OK Daily Study
The OK Daily Study is a multi-centred, part-randomised, part blinded, four cohort study. We are exploring daily dietary supplementation with vitamin K2, specifically menaquinone-7 (MK-7), given to breastfed infants or…
- Trial name
- NCT07620236
- Testing
- Combined MK-7 + vitamin D3 drops, Vitamin D3 Drops, MK-7 capsules
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Sarcoidosis, Vitamin D Insufficiency
Vitamin D Homeostasis in Sarcoidosis
This study evaluates the relationship between vitamin-D status and severity of sarcoidosis, and the effects of vitamin-D repletion in vitamin-D insufficient patients with sarcoidosis.
- Trial name
- NCT03621553
- Testing
- Ergocalciferol, Calcium Citrate with Vitamin D2
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Texas Southwestern Medical Center
Vitamin Deficiencies
Trial Comparing Elan Specialized Bariatric Supplements With Standard Multivitamins in Patients Undergoing Bariatric Procedures
Obesity has escalated to pandemic levels, impacting over 650 million adults globally and significantly contributing to the burden of non-communicable diseases such as type 2 diabetes, cardiovascular disease, obstructive sleep…
- Trial name
- NCT07021170
- Testing
- Elan Believe, Elan Compass, Elan Supreme
- Where
- Egypt
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Adequate Vitamin C Status, Inadequate Vitamin C Status
Anti-inflammatory Activities of Vitamin C Supplementation on the Gut Barrier Function in Adults With Obesity
This study is testing whether taking vitamin C every day can help improve gut health and reduce inflammation in adults with obesity.
- Trial name
- NCT07151105
- Testing
- Vitamin C Supplement + Low Vitamin C Diet
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Ohio State University
Peri Implant Mucositis, Peri Implant Bone Loss
Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Introduction: Dental implants offer a durable, aesthetic, and functional option for tooth replacement. However, they are not immune to failure.
- Conditions
- Peri Implant Mucositis, Peri Implant Bone Loss, Peri Implantitis, Calcium Deficiency
- Trial name
- NCT07766707
- Where
- Spain
- Volunteers
- 192 people
- Sponsor
- University of Barcelona
Triple Negative Breast Cancer, Vitamin D Deficiency
Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
A two arm pilot study investigating the rate of pathologic complete response in patients with vitamin D deficiency and triple negative breast cancer undergoing standard neoadjuvant chemotherapy + vitamin D supplementation…
- Conditions
- Triple Negative Breast Cancer, Vitamin D Deficiency, Invasive Breast Cancer
- Trial name
- NCT04677816
- Testing
- Standard of Care Neoadjuvant Chemotherapy (NAC), Vitamin D3, Drug Diary
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Major Depressive Disorder (MDD), Thiamine
Oral Thiamine (Vitamin B1) for Depression in Children and Adolescents
The goal of this study is to examine the effectiveness of thiamine in reducing depressive symptoms in children and adolescents. The investigators hypothesize that thiamine administration will alleviate depressive symptoms in…
- Conditions
- Major Depressive Disorder (MDD), Thiamine, Vitamin B1, Thiamine Diphosphate (TDP)
- Trial name
- B1Ped (NCT07793071)
- Testing
- thiamine hydrochloride 100 mg
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Vitamin D Deficiency, Obstructive Sleep Apnea
Vitamin D Status in Obstructive Sleep Apnea With and Without Comorbidities
This retrospective observational study evaluates the relationship between vitamin D status and obstructive sleep apnea (OSA) in adults.
- Trial name
- NCT07788391
- Where
- Turkey (Türkiye)
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Graft Vs Host Disease, Vitamin A Deficiency
Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.
The investigators hypothesize that single oral high dose supplementation with vitamin A will reduce the incidence of moderate-severe chronic graft-versus-host disease (GVHD) compared with placebo.
- Conditions
- Graft Vs Host Disease, Vitamin A Deficiency, Vitamin D Deficiency
- Trial name
- NCT06450925
- Testing
- Vitamin A
- Where
- 3 sites in United States
- Volunteers
- 190 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Vitamin B12 Deficiency, Renal Failure , Chronic
Oral Versus Intravenous Vitamin B12 Replacement in Hemodialysis Patients
The goal of this clinical trial is to learn whether intravenous (IV) vitamin B12 works better than oral vitamin B12 to correct vitamin B12 deficiency in adults on maintenance hemodialysis.
- Conditions
- Vitamin B12 Deficiency, Renal Failure , Chronic, Renal Dialysis
- Trial name
- B12-HD-RCT (NCT07781020)
- Testing
- Mecobalamin IV Injection, Mecobalamin Tablets
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jinnah Hospital
Vitamin D
Comparing Vitamin D Results and Acceptability of Sampling Obtained From Dried Blood Spot, Tasso+ Capillary Sampling, and Venous Blood.
This study will evaluate the performance and acceptability of different sampling methods for measuring vitamin D, specifically 25-hydroxyvitamin D₂ and 25-hydroxyvitamin D₃.
- Trial name
- VitD TASSO (NCT07782528)
- Testing
- Vit D Tasso+
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Polycystic Ovarian Syndrome in Adolescent Females, Vitamin D Deficiency
Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)
This study is a double blind, placebo controlled, randomized trial of study subjects with PCOS and low vitamin D to 2 groups- placebo and vitamin D replacement.
- Trial name
- NCT04355572
- Testing
- Vitamin D 4000IU daily
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Those Who Provided Written Informed Consent, Female Gender
The Effect of a Patient Education Program on Vitamin D Levels and Health Beliefs Regarding Vitamin D Use
Background and Rationale: Vitamin D deficiency is a major public health concern. While clinical guidelines provide treatment protocols, medication adherence remains a significant barrier to achieving target serum levels.
- Conditions
- Those Who Provided Written Informed Consent, Female Gender, Aged 18 Years and Older, Hypothyroidism Disease
- Trial name
- NCT07535671
- Testing
- Educational with vitamin D
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
D Vitamin Deficiency Patients
Vitamin D Supplementation and the Immune Response
The main objective is to assess the variation in plasma levels of cathelicidin before and after influenza vaccination. All bibliographic data suggests that supplementation vitamin D in the elderly often deficient in this vitamin…
- Trial name
- NCT01893385
- Testing
- Vitamin D (drug)
- Where
- France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Clermont-Ferrand
Locally Advanced Cervical Cancer, Vitamin D Concentration
Vitamin D Status and Clinical Outcomes in Locally Advanced Cervical Cancer
Background. Definitive chemoradiotherapy represents the standard therapeutic approach for the management of locally advanced cervical cancer.
- Trial name
- CERVITAL (NCT07743918)
- Testing
- Pretreatment Vitamin D Assessment in Serum and Cervical Lavage Fluid
- Where
- Serbia
- Volunteers
- 100 people
- Sponsor
- University of Kragujevac
Cholestatic Liver Disease, Chronic Liver Disease (CLD)
Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency
The goal of this clinical trial is to learn whether adding calcitriol to vitamin D2 can improve vitamin D deficiency in children with cholestasis and chronic liver disease.
- Conditions
- Cholestatic Liver Disease, Chronic Liver Disease (CLD), Vitamin D Deficiency, Children
- Trial name
- VITD-CHOL (NCT07670611)
- Testing
- Vitamin D2, Calcitriol
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Chulalongkorn University
Vitamin D Insufficiency
25(OH)-Vitamin D and Its Association With Structural and Functional Parameters in Hospitalized Patients With Neurological Diseases
The NeuroVitD study aims to assess vitamin D levels in hospitalized cohorts with neurological disorders resulting in motor disabilities, providing epidemiological data necessary for guidelines.
- Trial name
- NeuroVitD (NCT06791044)
- Testing
- DELTIUS
- Where
- 2 sites in Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dionyssiotis, Yannis, M.D.
Premature, Preterm Infant Health
Vitamin A Supplementation and Breast Milk Vitamin A Levels in Mothers of Preterm Infants
Preterm infants are at increased risk of vitamin A deficiency because they are born with low vitamin A stores and depend largely on breast milk to meet their nutritional needs.
- Conditions
- Premature, Preterm Infant Health, Vitamin A Deficiency, Human Milk
- Trial name
- VITAL (NCT07736768)
- Testing
- Oral multivitamin containing vitamin A
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Mississippi Medical Center