Clinical trials: Vitreous Hemorrhage
Diabetic Retinopathy, Postoperative Recurrent Vitreous Hemorrhage
A Prospective Study of Ranibizumab in the Treatment of Postoperative Recurrent Vitreous Haemorrhage of Diabetic Retinopathy
Diabetic retinopathy (DR) is one of the main complications in diabetes, the proliferative diabetic retinopathy (PDR) is the most important one of the reasons leading to decreased vision, PDR is the stage of clinical intervention.
- Conditions
- Diabetic Retinopathy, Postoperative Recurrent Vitreous Hemorrhage, Pars Plana Vitrectomy, Ranibizumab
- Trial name
- NCT05248334
- Testing
- Ranibizumab Injection, PPV
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tianjin Medical University Eye Hospital
Diabetic Retinopathy, Vitreous Hemorrhage
IVB for Post-vitrectomy Hemorrhage in Diabetic Eyes
Recurrent vitreous hemorrhage following pars plana vitrectomy (PPV) for proliferative diabetic retinopathy remains a significant complication with reported incidence ranging from 11 to 75%.
- Trial name
- NCT06559488
- Testing
- Bevacizumab Injection [Avastin], Pars Plana Vitrectomy
- Where
- Indonesia
- Volunteers
- 18 people
- Sponsor
- Universitas Padjadjaran
Diabetic Retinopathy, Macular Edema
20- Versus 23- Gauge System for Pars Plana Vitrectomy
The aim of the present study is to compare the functional and clinical differences and advantages between a standard operating system and a newly developed even smaller system for pars plana vitrectomy.
- Conditions
- Diabetic Retinopathy, Macular Edema, Postoperative Complications, Vitreous Hemorrhage
- Trial name
- NCT00411970
- Testing
- 20- and 23 gauge vitreoretinal surgery systems
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Macular Holes, Intraocular Lens Opacification
Oral Sedation in Vitreoretinal Surgery
The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.
- Conditions
- Macular Holes, Intraocular Lens Opacification, Vitrectomy, Vitreous Hemorrhage
- Trial name
- NCT04346095
- Testing
- Oral Sedatives with or Without Analgesia, Intravenous Sedatives with or Without Analgesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Recurrent, Hemorrhage
Adjuvant Intravitreal Bevacizumab in Pars Plana Vitrectomy for Diabetic Vitreous Hemorrhage
Postoperative vitreous hemorrhage is a common complication after vitrectomy for proliferative diabetic retinopathy. There have been efforts to lower the incidence of postoperative vitreous hemorrhage such as preoperative…
- Trial name
- ABeVi (NCT01151722)
- Testing
- bevacizumab injection
- Where
- Brazil
- Volunteers
- 2 people
- Sponsor
- University of Sao Paulo
Vascular Retinopathy of Left Eye (Disorder), Vascular Retinopathy of Right Eye (Disorder)
Intraoperative Application of Fluorescein Sodium Angiography in Vascular Retinopathy
The study used a new surgical technique: intraoperative fluorescence imaging,In the 1980s, some scholars proposed the concept of intraoperative fluorescein angiography.During vitrectomy, intraoperative fluorescein angiography…
- Conditions
- Vascular Retinopathy of Left Eye (Disorder), Vascular Retinopathy of Right Eye (Disorder), Diabetic Retinopathy, Retinal Vein Occlusion
- Trial name
- NCT06343961
- Testing
- Intraoperative Fluorescein Angiography
- Volunteers
- 80 people
- Sponsor
- Jie Zhong
Proliferative Diabetic Retinopathy, Vitreous Hemorrhage
Cryoapplication Versus Anti-VEGF Before Diabetic Vitrectomy
Pars-plana vitrectomy (PPV) is the cornerstone of surgical treatment for eyes with complicated proliferative diabetic retinopathy. Anti-VEGF intravitreal injection before PPV has shown a good effect on surgical outcomes.
- Conditions
- Proliferative Diabetic Retinopathy, Vitreous Hemorrhage, Tractional Retinal Detachment
- Trial name
- NCT05514925
- Testing
- Bevacizumab Injection [Avastin], Peripheral Retinal Cryoapplication
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- Khairallah Moncef
Cataract, Retina Detachment
Different Hemostasis According to the Anesthetic Agents
We investigated the hemostatic differences according to the main anesthetic agents by analyzing rotational thromboelastometry (ROTEM) under the hypothesis that propofol-based anesthesia would impair postoperative coagulability…
- Conditions
- Cataract, Retina Detachment, Pterygium, Keratitis
- Trial name
- NCT02151305
- Testing
- Propofol, remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Bundang Hospital
Proliferative Diabetic Retinopathy
Gas Tamponade for Prevention of Postoperative Vitreous Hemorrhage in Diabetics
Hypothesis: Patients undergoing pars plana vitrectomy for the indication of diabetic vitreous hemorrhage will have a lower incidence of postoperative vitreous hemorrhaging during the 6-month trial period when vitreous…
- Trial name
- NCT04380077
- Testing
- vitrectomy with sulfur hexafluoride gas, vitrectomy with balanced salt solution
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Rush Eye Associates
Proliferative Diabetic Retinopathy
Intravitreal Bevacizumab Pretreatment for Reducing Preretinal Hemorrhage in Diabetic Vitrectomy
Treatment of severe proliferative diabetic retinopathy (PDR) may require the use of silicone oil for long-term retinal tamponade to prevent recurrent retinal detachment.
- Trial name
- NCT00596505
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- National Taiwan University Hospital
Diabetic Vitreous Hemorrhage
Intravitreal Aflibercept Injection or Early Vitrectomy for Diabetic Vitreous Hemorrhage
Prospective study comparing efficacy and safety of intravitreal aflibercept injection and panretinal photocoagulation to early vitrectomy for patients with diabetic vitreous hemorrhage.
- Trial name
- NCT04153253
- Testing
- Aflibercept Injection [Eylea], Vitrectomy
- Where
- Kuwait
- Volunteers
- 34 people
- Sponsor
- Al Hadi Hospital
Proliferative Diabetic Retinopathy, Diabetic Traction Retinal Detachment
Prospective Randomized Controlled Study of Intravitreal Injection of Bevacizumab for Proliferative Diabetic Retinopathy
We hypothesized that to reduce the adverse effects of intravitreal bevacizumab on ocular tissue and whole body, intravitreal injection of a low concentration of bevacizumab and conducting vitrectomy shortly after the injection is…
- Conditions
- Proliferative Diabetic Retinopathy, Diabetic Traction Retinal Detachment, Vitreous Hemorrhage
- Trial name
- NCT01854593
- Testing
- Bevacizumab, Vitrectomy
- Where
- Japan
- Volunteers
- 69 people
- Sponsor
- Nihon University
Vitreous Hemorrhage, Diabetic Retinopathy
Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage
The purpose of this study is to determine if intravitreal injection of Vitrase (ovine hyaluronidase) clears vitreous hemorrhage
- Trial name
- NCT00198497
- Testing
- Vitrase
- Where
- 58 sites in Australia, Brazil and 7 more
- Volunteers
- 510 people
- Sponsor
- Bausch & Lomb Incorporated
Vitreous Hemorrhage Secondary to PDR
Adjuvant Intravitreal Bevacizumab in Pars Plana Vitrectomy for Vitreous Hemorrhage
The purpose of this study is to determine the effect of pre and intra-operative bevacizumab injection on postoperative vitreous hemorrhage after diabetic vitrectomy in comparison to vitrectomy without bevacizumab injection.
- Trial name
- NCT01091896
- Testing
- Bevacizumab
- Where
- Brazil
- Volunteers
- 1 people
- Sponsor
- University of Sao Paulo
Proliferative Diabetic Retinopathy
Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy
To evaluate if intravitreal Ozurdex can reduce the incidence of recurrent vitreous hemorrhage after primary pars plana vitrectomy (PPV) in patients with proliferative diabetic retinopathy (PDRP).
- Trial name
- NCT01478737
- Testing
- Intravitreal dexamethasone implant, Vitrectomy
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Anders Kvanta
Diabetic Vitreous Hemorrhage
Panretinal Photocoagulation During Vitrectomy for Diabetic Vitreous Hemorrhage
In this randomized clinical trial, the authors compare two cohorts receiving different endolaser spot amounts with similar laser settings in PDR subjects naïve to PRP undergoing PPV for the indication of VH.
- Trial name
- NCT05318742
- Testing
- laser
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Panhandle Eye Group, LLP
Vitrectomy, Retinal Detachment
Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter
Report efficiency and clinical outcomes using 25-gauge, bevel-tip, 20000 cut per minute vitrectomy probe among eyes with various vitreo-retinal diseases
- Conditions
- Vitrectomy, Retinal Detachment, Vitreous Hemorrhage, Macular Holes
- Trial name
- HYPE (NCT04404296)
- Testing
- 25-gauge, bevel-tip, 20000 cut per minute pars plana vitrectomy
- Where
- Philippines
- Volunteers
- 50 people
- Sponsor
- Peregrine Eye and Laser Institute
Diabetic Retinopathy, Vitreous Hemorrhage Due to Diabetes Mellitus
Pre-operative Vabysmo in Patients With Non-clearing Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy
In this phase IV, randomized, double-masked, sham-controlled study the investigators hope to determine the efficacy in peri-operative faricimab (Vabysmo) compared to sham in limiting complications from pars plana vitrectomy for…
- Trial name
- NCT06191094
- Testing
- Faricimab Injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Proliferative Diabetic Retinopathy, Vitreous Hemorrhage
Pre- and Intra-operative Intravitreal Bevacizumab Injection in Diabetic Vitrectomy
The purpose of this study is to determine the effect of pre- and intra-operative bevacizumab injection on postoperative vitreous hemorrhage after diabetic vitrectomy.
- Trial name
- IBDV (NCT00745498)
- Testing
- Bevacizumab
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Bundang Hospital
Anti-VEGF, Branch Retinal Vein Occlusion
Anti-VEGF Instead of Intraoperative Fan-shaped Photocoagulation in BRVO Combined With Vitreous Hemorrhage
To evaluate the efficacy and safety of Anti-VEGF instead of intraoperative fan-shaped photocoagulation in BRVO combined with vitreous hemorrhage.
- Conditions
- Anti-VEGF, Branch Retinal Vein Occlusion, Vitrectomy
- Trial name
- NCT03637283
- Testing
- anti-VEGF, fan-shaped photocoagulation
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University