Clinical trials: Vocal Cord Dysfunction
Larynx, Obstruction
CLE During Exercise Testing in Asthma
The purpose is to assess visualize the level of laryngeal obstruction and vocal cord dysfunction and to obtain more information on causes for dyspnea in asthma and severe asthma and to assess safety of CLE in patients with asthma…
- Conditions
- Larynx, Obstruction, Vocal Cord Dysfunction
- Trial name
- CLEtesting (NCT04168671)
- Testing
- Continuous laryngoscopy during exercise test
- Where
- Finland
- Sponsor
- Helsinki University Central Hospital
Vocal Cord Paresis, Acquired Vocal Cord Palsy
The Incidence and Impact of Vocal Cord Dysfunction In Patients Undergoing Thoracic Surgery
Population-based single centre, blinded, prospective cohort study of the impact of recurrent laryngeal nerve (RLN) injury on Thoracic Surgery patients.
- Trial name
- NCT02996526
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- University of Manitoba
Breathing, Mouth, Lung Function Decreased
Evaluating the Use of a Device Called Impulse Oscillometry in Participants With Vocal Cord Disorders or Asthma
This study will determine if airway resistance to airflow and pressure, measured by Impulse Oscillometry, is impacted in subjects with vocal cord disorders and whether these measurements are different when compared to subjects…
- Conditions
- Breathing, Mouth, Lung Function Decreased, Vocal Cord Dysfunction, Laryngeal Obstruction
- Trial name
- NCT05246930
- Testing
- Impulse Oscillometer
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Rochester
Disorder of Vocal Cord
Exercise-induced Paradoxical Vocal Fold Motion Disorder: Clinical Features and Potential Mechanisms
Exercise-induced paradoxical vocal fold motion disorder (E-PVFMD) - which severely impacts the lives of up to 1 million adolescents in the U.S.
- Trial name
- NCT02947009
- Testing
- Diagnostic Study
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Pittsburgh
Aging
Technology-assisted Vocal Exercise for Older Adults
Many detrimental effects of aging have been identified in the human voice, most of which are accepted as "normal". However, age-related vocal deficits disrupt communication and decrease quality of life in older adults and may be…
- Trial name
- NCT03015870
- Testing
- Vocal exercise with real-time feedback, Vocal exercise with recording
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Dyspnea
Pulmonary Function Test, Bronchial Hyperresponsiveness and Quality of Life in Patients With Vocal Cord Dysfunction (VCD)
Vocal cord dysfunction is a rare clinical picture. It is labeled as a sudden and threatening dyspnea. Patients with VCD may also present cough, hoarseness, wheezing, and chest tightness, but an inspiratory stridor is the most…
- Trial name
- VCD (NCT00906867)
- Testing
- Methacholine challenge testing, Rhino-laryngoscopy
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Thyroid Diseases, Hypocalcemia
Use of Prophylactic Steroids in the Prevention of Post-thyroidectomy Hypocalcaemia and Voice Dysfunction
Total thyroidectomy for benign surgical pathologies is associated with risks related to temporary hypocalcaemia and vocal quality dysfunction.
- Conditions
- Thyroid Diseases, Hypocalcemia, Vocal Cord Dysfunction
- Trial name
- NCT04752852
- Testing
- Dexamethasone
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Pakistan
Paradoxical Vocal Fold Motion Disorder, Vocal Cord Dysfunction
Treatment of Paradoxical Vocal Fold Motion Disorder (PVFMD) With a Form of Respiratory Retraining Technique
Paradoxical Vocal Fold Motion Disorder (PVFMD), otherwise known as vocal cord dysfunction (VCD) is a laryngeal breathing disorder that has several potential causes. In some individuals, exertion is the predominant trigger.
- Trial name
- PVFMDRespRet (NCT02859974)
- Testing
- Respiratory retraining for PVFMD
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Vocal Cord Dysfunction
Symptom Scoring for Predicting Vocal Cord Dysfunction (VCD)
Dr. Russell Traister, et al, describes a symptom scoring system based on retrospective chart review to help identify subjects with VCD. Dr.
- Trial name
- NCT05114083
- Testing
- symptom assessment
- Sponsor
- Ohio State University
Laryngospasm, Bradycardia
Noninferiority Clinical Trial With Laryngeal Mask and Endotracheal Tube
The purpose of this study is to determine whether the use of laryngeal mask classic as method for securing the airway in the population of 2 years to 14 years is associated with risk of laryngospasm as compared with the use of…
- Trial name
- NCT01288248
- Testing
- Airway laryngeal mask classic, endotracheal tube
- Where
- Colombia
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Laryngismus
Laryngeal Mask Airway (LMA) Insertion With Sevoflurane and Remifentanil
The purpose of this study was to determine the most suitable effect-site concentration of remifentanil for the LMA insertion during inhaled induction with 8% sevoflurane in adults.
- Trial name
- NCT01456299
- Testing
- Remifentanil 1, Control, Remifentanil 2
- Where
- South Korea
- Volunteers
- 102 people
- Sponsor
- Gachon University Gil Medical Center
Vocal Cord Dysfunction, Speech Disorders
Clinical Feasibility & Validation of the Virtual Reality GlenxRose Speech-Language Therapies
Factors related to successful rehabilitation are often directly related to adherence; for instance, dosage, frequency, and intensity can burden the patient regarding time and motivational factors.
- Trial name
- NCT05695131
- Testing
- GlenXRose Virtual Reality Speech Therapies
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Asthma, Heart Failure
The General Breathing Record Study
This study will test the use of a new handheld device (called the N-Tidal C), that measures a person's tidal breath carbon dioxide, in diagnosing the cause of someone's breathlessness.
- Conditions
- Asthma, Heart Failure, Pneumonia, Motor Neuron Disease
- Trial name
- GBRS (NCT03356288)
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TidalSense
Eye Abnormalities, Arrythmia
Relation Between Oculocardiac Reflex and Laryngospasm
The aim of this study is to evaluate whether there is a significant relation between various arrhythmias during the surgeon's stretching the eye muscles and laryngospasm and emergence agitation in strabismus surgeries
- Trial name
- NCT05339880
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- TC Erciyes University
Vocal Cord Dysfunction
Clinical Study of Regeneration on Larynx Soft Tissue Guided by Functional Collagen Scaffold
This study is carried out to explore the short-term and long-term efficacy of the functional collagen scaffold in guiding laryngeal soft tissue regeneration.
- Trial name
- NCT02754284
- Testing
- Autologous fat transplantation, Functional collagen scaffold transplantation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese Academy of Sciences
Laryngospasm
The Effect of Intravenous Lidocaine on Post-extubation Laryngospasm
In the literature, we found no randomized clinical trials addressing the using of IV lidocaine as prophylaxis for postoperative laryngospasm among adults.
- Trial name
- NCT01445847
- Testing
- Lidocaine
- Where
- Saudi Arabia
- Volunteers
- 134 people
- Sponsor
- King Saud University
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Laryngospasm, Hypoxemia
Prevention and Treatment of Laryngospasm and Hypoxemia Based on Risk Factors in Adult Outpatients Undergoing EGD
The purpose of this study is to identify patient and provider-chosen factors that put patients at risk for the development of hypoxemia (oxygen saturation < 90% for 5 seconds) during endoscopy and to use this knowledge to develop…
- Trial name
- NCT04159116
- Testing
- Prophylactic suctioning when clinically indicated
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Envision Healthcare Scientific Intelligence, Inc.
Laryngomalacia, Laryngospasm
Manual Valsalva Maneuver As a Preventive Measure of Postoperative Laryngospasm in Laryngomalacia Cases Undergoing Supraglottoplasty
We hypothesized that manual valsalva maneuver prevent incidence of postoperative laryngospasm after supraglottoplasty for cases of congenital laryngomalacia.
- Trial name
- NCT06627660
- Testing
- Valsalva maneuver
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Paradoxical Vocal Fold Motion, Vocal Cord Dysfunction
Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion
Paradoxical Vocal Fold Motion (PVFM) is a condition where vocal cords adduct (move toward another) instead of abduct (move away from one another) during inspiration, thus causing shortness of breath.
- Trial name
- NCT05770518
- Testing
- Biofeedback, Laryngeal control therapy (LCT)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Washington University School of Medicine