Clinical trials: Voiding Disorders
Urinary Incontinence
Toilet Training and Adults With Learning Disabilities
Incontinence is common in adults with learning disabilities (LDs). Behavioural toilet training in conjunction with toilet alarms is recommended for people with LDs, but there is a paucity of research, thus evidence-based…
- Trial name
- NCT05626062
- Testing
- Toilet alarm
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Glasgow Caledonian University
Male Stress Urinary Incontinence
Study of Urethral Mobility in Male Stress Urinary Incontinence Pre- and Post- Placement of Transobturator Sling
The hypothesis is men with stress urinary incontinence, including those following radical retropubic prostatectomy and other prostate surgery, have preoperative urethral mobility as measured by magnetic resonance imaging (MRI)…
- Trial name
- NCT01779323
- Testing
- Pre and Post Sling Pelvic MRI
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Duke University
Urinary Incontinence
Effects of Paula Exercises and Tibial Nerve Stimulation in Stress Urinary Incontinence
The aim of this study is to compare the combined effects of Paula method \& tibial nerve stimulation on incontinence, pelvic floor muscles strength, sexual function and quality of life in stress urinary incontinence
- Trial name
- NCT07576205
- Testing
- Paula Exercises, Tibial Nerve Stimulation
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Incontinence, Urinary
Clinical Study Investigating Safety and Performance of a New Urinary Intermittent Catheter in Healthy Volunteers
The aim of the study is to test the performance and safety of a newly developed intermittent catheter in healthy volunteers.
- Trial name
- NCT02965066
- Testing
- Coloplast Test Catheter, Coloplast Speedicath
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Pregnancy, Urinary Incontinence
Effect of Pelvic Floor Muscle Training Included in General Fitness Classes During Pregnacy
To investigate the effect of pelvic floor muscle training taught in a general exercise class during pregnancy to prevent urinary incontinence in nulliparous continent pregnant women.
- Trial name
- NCT01578369
- Testing
- Exercise classes with pelvic floor muscle training
- Where
- Spain
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Quality of Life, Stroke, Acute
Cerebrovascular Disease: Quality of Life (CODE: QoL)
The goal of this observational study is to learn about quality of life, stress and caregiver burden in patients with stroke and their caregivers.
- Conditions
- Quality of Life, Stroke, Acute, Sexual Behavior, Stress
- Trial name
- CODE:QoL (NCT06443268)
- Testing
- questionnaire, hair samples, blood samples, clinical exam
- Where
- Switzerland
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Stress Urinary Incontinence
Solyx Single-Incision SlingDynamic Intraoperative Standing Sling Technique (DISST) as an Office-based Procedure
This study will assess the feasibility and success of performing the SolyxTM SIMUS in the office using the Dynamic Interactive Standing Sling Technique (DISSTTM).
- Trial name
- NCT03842410
- Testing
- Single-Incision Sling
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michigan Institution of Women's Health PC
Stress Incontinence, Female, Overactive Bladder
Mindfulness Exercises to Reduce Anxiety and Pain During Urodynamic Testing
In this pilot study the investigators attempt to answer the question, does mindfulness exercises before urodynamic testing reduce patient's perception of anxiety or pain?
- Conditions
- Stress Incontinence, Female, Overactive Bladder, Lower Urinary Tract Symptoms
- Trial name
- NCT03625843
- Testing
- Mindfulness exercises
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Human Papilloma Virus Infection
Developing Methods to Investigate Additional Opportunities of HPV Vaccination by Using First-void Urine Samples
The main objective of this study is to develop protocols using FV urine that investigate in vitro whether infectious virions can be neutralized by HPV vaccination.
- Trial name
- HPV-VACPLUS (NCT04391647)
- Testing
- First-void urine collection, Blood draw
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Pelvic Floor Disorders, Urinary Incontinence
Effects of Epi-no Device on Pelvic Floor Dysfunctions
Perineal injury is the most common maternal obstetric complication associated with vaginal delivery. Perineal traumas are associated with maternal morbidity, including pain, urinary and fecal incontinence, genital prolapses…
- Conditions
- Pelvic Floor Disorders, Urinary Incontinence, Dyspareunia, Lacerations Perineal
- Trial name
- NCT04955418
- Testing
- Epi-No®, Evaluation
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Breast Cancer, Urine
Investigation of Urinary Biomarkers for the Detection of Breast Cancer
The aim of this study is to investigate and possibly validate urinary biomarkers for breast cancer. During this study the focus will be on aberrations of selected genes as prognostic or predictive value has been shown for these…
- Conditions
- Breast Cancer, Urine, Liquid Biopsy
- Trial name
- URODETECT-WP3 (NCT05453591)
- Testing
- Colli-Pee UAS devices
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Novosanis NV
Urinary Incontinence, Urinary Incontinence, Urge
Mindfulness-Based Stress Reduction Techniques and Yoga for Treatment of Urinary Urge Incontinence (MBSR-Yoga)
Many women experience the accidental loss of urine called urge incontinence or overactive bladder (OAB) incontinence. Women describe this as a sudden, strong desire to pass urine which results in leakage before reaching the…
- Trial name
- MBSR-Yoga (NCT01470560)
- Testing
- Mindfulness-Based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Stress Urinary Incontinence
To Evaluate the Use of Bioresorbable Tephaflex™ Sling for Stress Urinary Incontinence
Urinary incontinence (UI) is a major public health issue affecting up to 25-50% of all women and has a detrimental impact on patient quality of life.
- Trial name
- Tephaflex (NCT03673488)
- Testing
- TephaFlex™ mid-urethral sling
- Where
- South Africa
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pelvic Floor Research Foundation of South Africa
Blood Pressure, Albuminuria
Effect of NWT-03 on Blood Pressure
Part 2 of the study will assess the effect of 2g of NWT-03 (an egg-white protein hydrolysate) on systolic and diastolic blood pressure and flow-mediated dilation in a crossover designed study in healthy adults with mild…
- Trial name
- NCT02144740
- Testing
- NWT-03, an egg-white protein hydrolysate
- Where
- Ireland
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Newtricious R&D BV
Urinary Incontinence, Stress
Efficacy and Safety Stress Urinary Incontinence Study
Study F1J-MC-SBBT will examine the effect of duloxetine treatment in women with SUI. The inclusion and exclusion criteria of this Phase 3 study will ensure that all subjects have a clinical diagnosis of SUI.
- Trial name
- NCT00475358
- Testing
- Duloxetine
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Kidney Disease, Proteinuria
Determination of Kidney Function
Much more about kidney disorders can be learned by determining kidney function. This research proposes to study the kidneys function by several parameters known as glomerular filtration rate (GFR), Renal Plasma Flow (RPF), and…
- Conditions
- Kidney Disease, Proteinuria, Autoimmune / Connective Tissue Diseases
- Trial name
- NCT00001978
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Urinary Incontinence, Spinal Cord Injury
Lumbar to Sacral Ventral Nerve Re-Routing
To assess the level of improvement in voiding function after lumbar to sacral ventral nerve re-routing procedure in Spinal Cord Injury and spina bifida patients
- Conditions
- Urinary Incontinence, Spinal Cord Injury, Spina Bifida
- Trial name
- NCT00378664
- Testing
- lumbar to sacral ventral nerve re-routing procedure
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kenneth Peters, MD
Urinary Incontinence
Ancillary Study of the Lessening Incontinence With Low-impact Activity Study
The parent trial that supports this ancillary research is a randomized controlled trial to evaluate the efficacy of a group-based yoga intervention to decrease the frequency and impact of urinary incontinence in ambulatory…
- Trial name
- NCT04776720
- Testing
- Yoga Practice Program, Physical Conditioning Program
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Quality of Life, Sexual Function
Effects of Structured Rehabilitation Program on Quality of Life in Rectal Cancer Patients- a Randomized Controlled Trial
Quality of life after rectal surgery is reported to be impaired. Side effects of surgery and/or neoadjuvant treatment as functional disturbances like sexual dysfunction, urinary incontinence, anal incontinence or stoma problems…
- Conditions
- Quality of Life, Sexual Function, Urinary Incontinence, Anal Incontinence
- Trial name
- NCT00895388
- Testing
- Structured Rehabilitation program
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital of North Norway