Clinical trials: Voiding Disorders
Healthy, Stress Urinary Incontinence
Pelvic Floor Displacement in Women With SUI and Healthy Women: An Ultrasound Study (Stress Urinary Incontinence)
Pelvic floor main role is to maintain continence. pelvic floor malfunction could lead to urinary incontinence (UI). The known prevalence of UI among women is 25%-72%, in about 25%-50% it is Stress Urinary Incontinence (SUI), SUI…
- Trial name
- SUI (NCT02930720)
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assuta Hospital Systems
Vaginal Laxity, Urinary Incontinence
Evaluation Using Intragen Fractional Radiofrequency With NeuViVa for the Treatment of Vaginal Laxity and Urogynecology Symptoms.
This study will evaluate the clinical efficacy of a Transcutaneous Fractional Radiofrequency Device (TFRF) for the treatment of vaginal laxity (VL) and urogynecological symptoms.
- Conditions
- Vaginal Laxity, Urinary Incontinence, Sexual Dysfunction
- Trial name
- NCT03280446
- Testing
- Intragen fractional radiofrequency with NeuViVa
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SHERRY Thomas
Stress Urinary Incontinence
Electromyographic (EMG) and Mechanomyographic (MMG) Comparison
The purpose of this study is to assess the delay between the detection (by mechanomyography-MMG) of rectus abdominis contraction and the detection of cough in cough effort.
- Trial name
- EMG-MMG (NCT00942370)
- Testing
- non invasive mechanomyographic device based on a 3 axes accelerometer
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Retention, Urinary
Exploratory Study Investigating the Urinary Bladder During Intermittent Catheterization in Healthy and Spinal Cord Injured Male and Female Subjects Using an Upright MRI Scanner
This is an exploratory study investigating morphological and physiological changes of the lower urinary tract and surrounding structures during IC use in individuals with SCI, and during normal voiding and IC use in healthy…
- Trial name
- NCT07384559
- Testing
- MRI scan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Urinary Retention, Colorectal Surgery
Prophylactic Use of Tamsulosin in the Prevention of Post-operative Urinary Retention in Men After Rectum Resection
The study will be a phase III double-blind randomized clinical trial. Participants will be recruited from the Department of General Surgery of the CHU de Québec - Saint-François-d'Assise and Hôtel-Dieu de Québec.
- Conditions
- Urinary Retention, Colorectal Surgery, Rectal Resection, Post-operative Urinary Retention
- Trial name
- R-POUR (NCT05941806)
- Testing
- pr Sandoz Tamsulosin, Glucose
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Amniotic Fluid Leakage
Study of a Diagnostic Device for Identifying Between Amniotic Fluid to Urine
The purpose of this study is to compare the reliability and validity of a new device with standard methods for diagnosing between amniotic fluid leakage due to premature rupture of the membranes (PROM) and urine.
- Trial name
- NCT01517633
- Testing
- BirthSign
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Proteinuria, Diabetic Nephropathy
Effect of Renin Angiotensin System Blockade on the Fas Antigen (CD95) and Asymmetric Dimethylarginine (ADMA) Levels in Type-2 Diabetic Patients With Proteinuria
In recent years, diabetic nephropathy, which may lead to dialysis treatment, is the most prevalent underlying disease of people in developed countries.
- Conditions
- Proteinuria, Diabetic Nephropathy, Chronic Kidney Disease
- Trial name
- NCT00893425
- Testing
- ramipril
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Urinary Stress Incontinence
Pelvic Floor Contraction in Different Positions Among Women With and Without Stress Urinary Incontinence
Examination of pelvic floor contraction in different positions among women with and without stress urinary incontinence (SUI) will be conducted via diagnostic ultrasound.
- Trial name
- NCT04288648
- Testing
- ultrasound examination
- Where
- Israel
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Urinary Incontinence
Development and Feasibility Testing of a Group-based PFMT Programme for Antenatal Women in Nanjing City in China
The main objective is to co-design and assess the practicality of group-based Pelvic floor muscle training (PFMT) programme in pregnant women. The co-design of the PFMT programme will involve the stakeholder meeting.
- Trial name
- NCT05242809
- Testing
- Group-based PFMT group
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- King's College London
Stress Urinary Incontinence
The Effect of Dorsal Genital Nerve Stimulation on Opening Urethral Pressure
This study aims to investigate the effect of electrical stimulation of the dorsal genital nerve on the urethral pressure in healthy women.
- Trial name
- NCT05804552
- Testing
- Dorsal genital nerve stimulation
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Thea Christoffersen
Healthy Volunteer, Pharmacokinetics of YM178
A Study to Investigate the Food Effect on the Pharmacokinetics of YM178 in Healthy, Non-elderly Volunteers
The purpose of the study is to evaluate the effect of food intake on the pharmacokinetics of YM178 in healthy, non-elderly adult subjects.
- Trial name
- NCT00965926
- Testing
- YM178
- Where
- Japan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Sexually Transmitted Diseases, Bacterial
Evaluation of the Use of the Colli-Pee Device to Collect First-void Urine for Molecular Detection of STIs
Study objectives: To evaluate the usability of the Colli-PeeTM device to collect first-void urine for nucleic acid detection of Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis and Mycoplasma genitalium.
- Trial name
- Colli-Pee (NCT02552914)
- Testing
- Colli-Pee
- Where
- Belgium
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Stress Urinary Incontinence, Postsurgical Pain
The Follow-up After Shorter Tapes Study. Effectiveness and Safety of Shorter Trans-obturator Tapes.
Urinary incontinence after pregnancy and labor affects 1 in 3 women and has a negative impact on quality of life (QOL), limiting women's physical activity and impairing sexual function.
- Conditions
- Stress Urinary Incontinence, Postsurgical Pain, Follow-Up Studies
- Trial name
- FAST (NCT06731985)
- Where
- Norway
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Urge Incontinence, Urgency-frequency Syndrome
Percutaneous Nerve Evaluation Trial Time
Sacral neuromodulation (SNM) was approved by the Food and Drug Administration (FDA) for the treatment of urgency incontinence (UUI) in 1998.
- Conditions
- Urge Incontinence, Urgency-frequency Syndrome, Overactive Bladder
- Trial name
- NCT06226220
- Testing
- Sacral neuromodulation
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Hematuria, Bladder Cancer
Role of Novel Urinary Genomic and Metablomic Markers in Diagnosis of Bladder Cancer in Patients With Hematuria
Our goal is to develop a noninvasive, fast and simple assay to detect BCa on the GeneXpert system and metablomic genes.
- Trial name
- NCT04317261
- Testing
- Xpert Bladder Cancer Monitor (Xpert Monitor) test and assay of urinary metabolomics (gene expression of CRAT and SLC)
- Where
- Egypt
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Urinary Incontinence, Stress
Weighted Vaginal Cones Versus Biofeedback in the Treatment of Urodynamic Stress Incontinence: a Randomized Trial.
The purpose of this study is to determine the objective (urodynamic) cure rates and effect on patient quality of life after six months of treatment for two different nonsurgical management options for genuine stress urinary…
- Trial name
- NCT00247286
- Testing
- weighted vaginal cones, Biofeedback
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Queen's University
Urinary Retention, Anesthesia, Spinal
Postoperative Urinary Retention in Orthopedic Patients
The objective of this study is to compare the incidence of postoperative urinary retention related to spinal anesthesia with morphine and spinal anesthesia associated with peripheral blockade in orthopedic procedures of lower…
- Conditions
- Urinary Retention, Anesthesia, Spinal, Orthopedic Procedures, Nerve Block
- Trial name
- NCT04298775
- Testing
- spinal anesthesia with morphine, spinal anesthesia without morphine + peripheral nerve block
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Urinary Incontinence,Stress
Correlation Between Changes in Sex Hormone Levels and Stress Urinary Incontinence in Women
The goal of this observational study is to learn about the relationship between stress urinary incontinence and endogenous steroids in women, especially its occurrence and severity with androgens and estrogens.
- Trial name
- NCT06109623
- Testing
- observation, sex hormone
- Volunteers
- 1,226 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Stress Urinary Incontinence
Laser Vaginal Treatment for SUI
RCT designed to answer the question: Does the application of Erbium: YAG laser treatment to the vagina improve urine control for women with SUI?
- Trial name
- NCT03671694
- Testing
- Erbium-YAG laser vaginal treatment
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre