Clinical trials: Voiding Disorders
Urgency Urinary Incontinence
Investigation of Brain Mechanisms Involved in the Urinary Continence Mechanism Associated With Aging
Urge urinary incontinence (UUI) is a common problem in older people which vastly reduces quality of life, yet the cause and mechanism of disease are not well understood.
- Trial name
- NCT04599088
- Testing
- Brain functional MRI with simplified urodynamics
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Overactive Bladder, Dementia
Higher Neural Changes Following Anticholinergic, Beta 3 Agonist, or Placebo in Patients With Overactive Bladder
Women presenting with overactive bladder symptoms will be randomized to one of 3 arms (anticholinergic, beta-3 agonist, placebo). They will undergo baseline cognitive testing, functional MRI of the brain.
- Conditions
- Overactive Bladder, Dementia, Lower Urinary Tract Symptoms, Incontinence, Urge
- Trial name
- NCT03817931
- Testing
- Anticholinergic, Beta-3 Agonists, Adrenergic, Functional magnetic resonance imaging (fMRI)
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
HIV/AIDS, Albuminuria
Optimal Management of HIV Infected Adults at Risk for Kidney Complications in Nigeria
In this study, the Investigators plan to determine the optimal means to prevent or slow the progression of kidney disease among genetically at-risk northern Nigerian HIV-infected adults.
- Conditions
- HIV/AIDS, Albuminuria, Kidney Diseases, Genetic Predisposition
- Trial name
- R3 (NCT03201939)
- Testing
- Lisinopril
- Where
- Nigeria
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Urologic Injuries, Urologic Diseases
Bladder Morphology Using 2 Different Catheter Designs
Demonstrate and compare the 3D morphology of the bladder wall in full and drained states with 2 different kinds of bladder catheters in place. (Foley Catheter vs. Cystosure Catheter)
- Conditions
- Urologic Injuries, Urologic Diseases, Bladder Infection, Urinary Tract Infections
- Trial name
- NCT03108079
- Testing
- Cystosure Urinary Access System, Foley Catheter
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The Pelvic Floor Institute
Pelvic Floor Disorders, Stress Urinary Incontinence
Educating Women About Pelvic Floor Disorders During Pregnancy
The purpose of this study is to assess the increase in knowledge of pregnant patients regarding pelvic floor disorders when comparing two educational interventions: written handouts vs interactive workshops.
- Conditions
- Pelvic Floor Disorders, Stress Urinary Incontinence, Pelvic Organ Prolapse
- Trial name
- NCT05440539
- Testing
- Written Handouts, Interactive Workshop
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Pelvic Organ Prolapse, Urinary Incontinence
Mesh Debate Awareness Among Non-urogynecologists. A Practical Survey Study.
This study evaluates the awareness of mesh discussions in urogynecology among non-urogynecologists. A web-based questionnaire will be sent to four groups. Group-1 is King's College Hospital doctors.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Complication of Surgical Procedure
- Trial name
- Mesh_Survey (NCT04010162)
- Testing
- Mesh debate awareness survey
- Where
- Turkey (Türkiye)
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Uludag University
Urinary Incontinence
Intravaginal Vibratory Stimulus and Pelvic Floor Muscle Training
This is a randomized blinded trial with non-probabilistic sampling for convenience. Our goal is to compare PFMT with intravaginal vibratory stimulus versus PFMT alone on the treatment of female urinary incontinence.
- Trial name
- NCT04150094
- Testing
- Pelvic floor muscle training (PFMT), Pelvic floor muscle training + intravaginal vibratory stimulus
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Stress Urinary Incontinence, Satisfaction
Patient-Centered Versus Physician-Centered Counseling MidUrethral Sling Videos
The decision making process for stress incontinence surgery is complex. A key gap in the literature is how to improve patient preparedness and satisfaction for mid-urethral sling (MUS) surgery that is reproducible and low cost.
- Trial name
- MUVi (NCT03198481)
- Testing
- Patient-Centered Counseling Video, Physician Counseling Video
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Urinary Incontinence
Physiotherapy to Treat Urinary Incontinence in Athletes
Nearly half of all adult women suffer with Urinary incontinence (UI), this is more common in athletes. UI is considered to be due to weak pelvic floor muscles.
- Trial name
- POsITIve (NCT03986411)
- Testing
- Phase 1: Qualitative interviews: Health care professionals, Phase 2: Physiotherapy for urinary incontinence, Phase 3: Qualitative Interviews: Participants
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Stress Urinary Incontinence
The Valsalva Urethral Profile : a Measure to Assess Stress Urinary Incontinence
Clinical and paraclinical appraisal of stress urinary incontinence (SUI) is mainly based on the assessment of pelvic floor muscles (PFM) contraction and urethral mobility, the measurement of the maximum urethral closure pressure…
- Trial name
- NCT04311814
- Testing
- Maximum urethral closure pressure during Valsalva (v-MUCP)
- Volunteers
- 695 people, healthy volunteers welcome
- Sponsor
- Poissy-Saint Germain Hospital
Human Papilloma Virus Infection
Standard Operating Procedures for Anti-HPV (Human Papillomavirus) Antibody Detection in First-void Urine (AB-SOP Study)
The aim of the study is to develop robust analytical protocols for first-void urine sample preparation and antibody assays to monitor natural and/or vaccine induced immunity against HPV (Human Papillomavirus).
- Trial name
- AB-SOP (NCT02714114)
- Testing
- First-void urine collection, Blood draw
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Inguinal Hernia, Urinary Retention
Effect of Inguinal Hernia Repair on Uroflowmetric Parameteres
Post operative acute urinary retension or voiding dysfunction are complications after inguinal hernia repair and they cause a great deal of discomfort and stress to patients.
- Conditions
- Inguinal Hernia, Urinary Retention, Lower Urinary Tract Symptoms
- Trial name
- NCT03450811
- Testing
- Inguinal hernia repair
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Urinary Incontinence, Frailty
Effects of a Multidisciplinary Intervention on Fall Risk and Urinary Incontinence in Older Women
This will be a quantitative, quasi-experimental, and longitudinal study spanning 18 weeks of intervention, followed by a 24-week follow-up, scheduled to begin in January 2025.
- Conditions
- Urinary Incontinence, Frailty, Balance Impairment
- Trial name
- FIRE-WOMEN (NCT06839040)
- Testing
- Group 1: ExVerbPsy, Group 2: ExVerb, Group 3: Ex
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Stress Urinary Incontinence (SUI)
Pelvic Floor Muscle Exercise and Progressive Muscle Relaxation for Stress Urinary Incontinence
Stress urinary incontinence (SUI) is a common condition in women that causes involuntary urine leakage during activities such as coughing, sneezing, laughing, or exercising.
- Trial name
- NCT07762391
- Testing
- Pelvic Floor Muscle Exercise, Progressive Muscle Relaxation (PMR), Combined Pelvic Floor Muscle Exercise and Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Stress Urinary Incontinence
Pilates Pelvic Floor Strengthening Program to Improve Urinary Incontinence
Does a twice weekly, 12-week Pilates pelvic floor strengthening program improve short- and long-term measures of stress urinary incontinence symptoms in women ages 45-70 years of age?
- Trial name
- NCT03118557
- Testing
- Pilates pelvic floor strengthening
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Urinary Incontinence,Stress
Kegel Exercises for Stress Urinary Incontinence
Study about a targeted group of women suffering from self-reported stress urinary incontinence, attend a Kegel exercise training program. The group was divided into two; supervised and unsupervised.
- Trial name
- NCT05529238
- Testing
- biofeedback training
- Where
- Australia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Charles Darwin University
Urinary Incontinence (UI), Pelvic Floor Disorders
Pelvic Floor Muscle Training and Neuromuscular Performance in Women's Rugby
This randomized controlled trial will evaluate whether a rugby-tailored pelvic floor muscle training programme reduces urinary incontinence symptoms and influences neuromuscular performance in professional and semi-professional…
- Trial name
- NCT07757633
- Testing
- Rugby-Tailored Pelvic Floor Muscle Training Programme
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Urinary Incontinence
Regaining Bladder Control in Postmenopausal Women With Osteoporosis
Conservative management for urinary incontinence has been shown to improve bladder control. We are conducting a study of the effectiveness of conservative management for urinary incontinence in women who also have osteoporosis.
- Trial name
- NCT00323245
- Testing
- Physiotherapy for urinary incontinence
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Preeclampsia
Predicitve Use of Spot Urine Protein/Creatinine Ratios in Preeclampsia
The investigators intend to perform a large prospective study looking at the predictability of the random urine protein-to-creatinine ratio compared to the gold standard 24-hour urine protein collection.
- Trial name
- NCT00870428
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Urinary Incontinence, Bladder Control
Promoting Self Care to Prevent Urinary Incontinence (UI): A Four-Year Follow-up
This study examined whether self-efficacy promoted adherence to Pelvic Floor Muscle Training (PFMT) and Bladder Training (BT) in women aged 55 and older.
- Trial name
- NCT00506766
- Testing
- Bladder Health Class consisting of 6 weekly group sessions, Practice PFMT and BT, Clinic examination for pelvic muscle function
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Michigan