Clinical trials: Volume
Volume Deficiency in the Mid-Face, Skin Laxity
A Study to Characterize Human Skin Changes From Biostimulator Treatments Via Non-invasive Imaging
Adult subjects with moderate-to-severe cheek wrinkles will be treated with Sculptra for correction of fine lines and wrinkles in the cheek area.
- Conditions
- Volume Deficiency in the Mid-Face, Skin Laxity, Photo-aged Skin
- Trial name
- NCT07399028
- Testing
- Sculptra®
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Galderma R&D
Male Contraception, Semen Volume
Effects of NLS-133, a Potential Non-Hormonal "On-Demand" Male Contraceptive
NLS-133-CLIN001 is a Phase 2a study designed to assess the safety, tolerability, and effects of NLS-133 (combination of two FDA-approved agents) compared to an active control (FDA-approved pharmacologic agent) or placebo on semen…
- Conditions
- Male Contraception, Semen Volume, Sperm Motility
- Trial name
- NCT07393334
- Testing
- NLS-133, Active Comparator #1
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Next Life Sciences
the Correction of Midface Volume Deficiency and/or Midface Contour Deficiency
The Correction of Midface Volume Deficiency and/or Midface Contour Deficiency
The objective of this clinical trial is to evaluate the efficacy and safety of PEGDE-crosslinked hyaluronic acid hydrogels for the correction of midface volume deficiency and/or midface contour deficiency, on the premise of…
- Trial name
- NCT07359079
- Testing
- Stimulate, Restylane Volyme
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Chongqing Jinsaixing Medical Technology Co., Ltd
Facial Volume Deficit
A Study to Assess Adverse Events and Effectiveness of HAC 22L Injection for Mid-Face Volume in Adult Participants
Collagen, elastin, and glycosaminoglycans, (eg, hyaluronic acid) are predominant component of the skin and they are key contributor to its characteristics such as strength, elasticity, and plumpness.
- Trial name
- NCT05818709
- Testing
- HAC 22L
- Where
- 17 sites in Germany, Spain
- Volunteers
- 61 people
- Sponsor
- AbbVie
Heart Failure With Volume Overload
A Study of HRS-9057 in Patients With Heart Failure and Volume Overload
The study is an open-label, Tolvaptan-controlled Phase I study to evaluate the safety, tolerability, PK/PD profile and efficacy of HRS-9057 in the treatment of heart failure with volume overload.
- Trial name
- NCT06506994
- Testing
- HRS-9057, Tolvaptan
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Mid-face Volume Deficiency
Clinical Investigation Evaluating the Safety and Feasibility of Adipearl
Adipearl is an injectable filler intended to be injected subcutaneously in the face.
- Trial name
- NCT06034522
- Testing
- Adipearl
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Volumina Medical S.A.
Face Volume Deficiency
Evaluation of Safety of Filler Injection in Subcutaneous Tissues
Adipearl is an injectable filler intended to be injected subcutaneously.
- Trial name
- NCT06322043
- Testing
- Adipearl
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Volumina Medical S.A.
Volume Deficiency in the Mid-Face, Aging
Study of STYLAGE® XXL for Volume Deficiency in the Mid-Face
The primary objective of the study is to demonstrate the superiority of STYLAGE® XXL versus no treatment at 24 weeks after baseline for the creation or restoration of volume deficit in the mid-face.
- Conditions
- Volume Deficiency in the Mid-Face, Aging, Aesthetics
- Trial name
- MidFaceXXL (NCT05355454)
- Testing
- STYLAGE® XXL
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Volume Deficiency in the Mid-Face, Aging
Study of a Novel Hyaluronic Acid Based Gel for Volume Deficiency in the Mid-face (FaceHyal)
The primary objective of the study is to demonstrate the superiority of IPN-21-SENSE versus no treatment at 24 weeks after baseline for the creation or restoration of volume deficit in the mid-face.
- Conditions
- Volume Deficiency in the Mid-Face, Aging, Aesthetics
- Trial name
- FaceHyal (NCT05747456)
- Testing
- IPN-21-SENSE
- Where
- France
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Facial Aging, Skin Rejuvenation
Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation
The aim of the study is to verify safety and performance of Semical dermal fillers according to real-world data.
- Conditions
- Facial Aging, Skin Rejuvenation, Volume Defects in the Mid-face, Lip Augmentation and Correction of Perioral Rhytids
- Trial name
- SEMDERMA (NCT07160777)
- Testing
- cross-linked hyaluronic acid, Mesolifter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Mid Face Volume Deficit
Evaluation of Efficacy and Safety of Alcarisa (Hyaluronic Acid Produced by Espad Pharmed Co.) for Restoration of Mid-face Volume
Mid-face volume loss is a factor affecting beauty that makes people feel uncomfortable about themselves. The purpose of this study is to evaluate the efficacy and safety of Hyaluronic Acid injection with the brand name Alcarisa®…
- Trial name
- NCT07126912
- Testing
- Alcarisa (hyaluronic acid filler)
- Where
- 2 sites in Iran
- Volunteers
- 30 people
- Sponsor
- Espad Pharmed
Facial Volume
Open, Non-comparative Study to Evaluate the Effectiveness and Safety of the Medical Device KOS® XL for the Restoration and/or Augmentation of Facial Volume
The process of facial aging is a result of intricate alterations occurring at both the microscopic and macroscopic levels, leading to changes in facial volume.
- Trial name
- NCT06828198
- Testing
- KOS® XL
- Where
- Romania
- Volunteers
- 34 people
- Sponsor
- Quantum Beauty Kozmetik
Facial Rhytides, Skin Folds
Study to Evaluate Subject Satisfaction With Facial Appearance and Impact of Combined Facial Treatment
The primary objective of this study is to quantify the psychological, social, and emotional impact of comprehensive aesthetic treatment with a portfolio of the Sponsor's products by measuring the change in subject's satisfaction…
- Conditions
- Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality
- Trial name
- NCT04609020
- Testing
- JUVÉDERM, BOTOX, HArmonyCA Lidocaine
- Where
- 6 sites in Brazil
- Volunteers
- 64 people
- Sponsor
- Allergan
Aesthetic, Aesthetic Rejuvenation
Clinical Investigation of the Medical Device "Alexa Volume" for Correction of Midface Volume Loss
This is a post-marketing, open-label, non-comparative, multi-center clinical investigation to evaluate the effectiveness and safety of the medical device "Alexa Volume" (DIACO BIOFARMACEUTICI S.r.l., Italy), based on cross-linked…
- Conditions
- Aesthetic, Aesthetic Rejuvenation, Midface Volumization, Age-related Volume Deficit in the Mid-face
- Trial name
- NCT06984419
- Testing
- Cross-linked hyaluronic acid dermal filler
- Where
- 4 sites in Poland, Ukraine
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Institute Hyalual GmbH
Hair Loss/Baldness, Wrinkle Appearance
Autologous Adipose Cells Therapy
Autologous Adipose Cell Therapy is a series of process designated to address the demerits of the traditional autologous fat grafting and dermal fillers, while enhancing the versatility and aesthetic outcomes.
- Conditions
- Hair Loss/Baldness, Wrinkle Appearance, Volume, Fine Lines
- Trial name
- NCT06869252
- Testing
- Autologous Adipose Cells Therapy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- CERM INC.
Buttocks Volume Loss
Clinical Study for the Evaluation of the Effectiveness of Use of a Poly-L Lactic Acid Injectable Filler for the Aesthetic Treatment of Buttocks Volume Depression
The purpose of this study is to assess the effectiveness and safety of Gana X, a Poly L-lactic acid filler for the aesthetic treatment of buttocks.
- Trial name
- PLLA (NCT05363163)
- Testing
- Gana X
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GCS Co., Ltd
Bladder Disease, Bladder Retention Volume
ECHO-012 Kosmos Bladder Clinical Validation Study
The goal of this clinical trial is to compare the Kosmos Automatic Bladder Volume to the manual annotated bladder volume in participants across gender (male and female), age (children ages 7-17 and adults 18-89), and BMI strata…
- Conditions
- Bladder Disease, Bladder Retention Volume, Bladder Dysfunction, Bladder Function
- Trial name
- NCT06792851
- Testing
- Kosmos Bladder Volume Algorithm
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- EchoNous Inc.
Cardiopulmonary Failure, Myocardial Infarction (MI)
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
The COR-INSIGHT trial aims to evaluate the effectiveness of Peerbridge COR advanced ambulatory ECG wearables (COR 1.0 and COR 2.0) in accurately and non-invasively detecting cardiovascular and cardiopulmonary conditions using…
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure
- Trial name
- COR-INSIGHT (NCT06763549)
- Testing
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Midface Volume Deficit
Sculptra for Correction of Midface Volume Deficit and/or Midface Contour Deficiency
This is a randomized, evaluator-blinded, no-treatment controlled study in participants with Midface Volume Deficit and/or Midface Contour Deficiency.
- Trial name
- NCT04132518
- Testing
- Sculptra
- Where
- 6 sites in China
- Volunteers
- 205 people
- Sponsor
- Galderma R&D
Midface Volume Deficit
To Evaluate the Performance and Safety of YVOIRE Volume Plus for Improvement of Mid-face Volume
A Study to Evaluate the Performance and Safety of YVOIRE volume plus for Temporary Improvement of Mid-face Volume
- Trial name
- NCT04784299
- Testing
- YVOIRE volume plus, Restylane Lyft with Lidocaine
- Where
- Germany
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- LG Chem