Clinical trials: Volume
Cardiac Disease
DEF-315 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY
This is a Phase 3, prospective, open-label, multicenter study to evaluate Left Ventricular Ejection Fraction (LVEF) measurement accuracy and reproducibility of DEFINITY® contrast-enhanced and unenhanced echocardiography as…
- Trial name
- BENEFIT2 (NCT03719612)
- Testing
- DEFINITY®
- Where
- 15 sites in United States
- Volunteers
- 160 people
- Sponsor
- Lantheus Medical Imaging
Brachial Plexus Blockade
Effect of Local Anaesthetic Volume on Axillary Brachial Plexus Block Duration
Axillary brachial plexus block is an safe, effective and widely used technique for providing surgical anesthesia at and below the elbow. Inadvertent intraneural and intravascular injections are the only significant risks.
- Trial name
- NCT03163472
- Testing
- Axillary brachial plexus block with 10 mL oof local anaesthetic, Axillary brachial plexus block with 30 ml of local anaesthetic
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Anesthesia
A Modeling of Changes in Tidal Volume With Concentration of Inhalational Anesthetics
modelling of tidal volume with inhalational anesthetic concentration
- Trial name
- NCT03491839
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Tooth Extraction, Tooth Extraction Site Healing
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Conditions
- Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- BTCPARPBV (NCT07638319)
- Testing
- Neocement Inject P® (Beta-Tricalcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Acute Pancreatitis
Early Goal-directed Volume Resuscitation in Severe Acute Pancreatitis
Acute pancreatitis (AP) is a common disorder with rising incidence varying between 35 and 80 per 100,000 in Europe and the USA. About 15% of patients develop necrotizing pancreatitis (NP) with a mortality of up to 42% and…
- Trial name
- EAGLE (NCT00894907)
- Testing
- PiCCO-parameter-guided volume resuscitation, Control-group
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- Technical University of Munich
Enteral Feeding
Does Volume-based Enteral Feeding Improve Nutrient Delivery in Hospitalized Critically Ill Children?
Background Some critically ill children have malnutrition which may worsen while they are in hospital and delay their return home. They can recover faster when they are given tube feedings to improve their nutrition.
- Trial name
- NCT05286177
- Testing
- Volume-based EN, Rate-based EN
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Endometrial Cancer, Cervical Cancer
The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.
The role of small-volume lymph node disease (ITC and micro metastases) among patients with endometrial or cervical cancer submitted to sentinel node (SLN) procedure is not clearly defined.
- Conditions
- Endometrial Cancer, Cervical Cancer, Sentinel Lymph Node, Micrometastasis
- Trial name
- ITCMicroUtCa (NCT04403867)
- Testing
- Sentinel lymph node (SLN) biosy +/- lymphadenectomy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Pulmonary Nodule, Solitary
The Benefit of UHR-CT: Precision of Repeated Volume Measurements of Pulmonary Nodules
To assess the variability of semi-automated volume measurements of pulmonary nodules on same-day repeated scans of equal radiation dose from two different CT scanners: One high-end CT scanner with standard spatial resolution…
- Trial name
- Coffee Break (NCT04209972)
- Testing
- Precision Ultra-High-Resolution CT scanner, Genesis high-end CT scanner
- Where
- Netherlands
- Volunteers
- 92 people
- Sponsor
- Radboud University Medical Center
Hemodynamic Instability, Anesthesia, General
Hemodynamics During Induction of General Anesthesia With Medium or Low Remifentanil Doses.
In this trial the investigators want to examine if there is any difference in hemodynamic stability during induction when comparing two low and a medium remifentanil dose and keeping propofol induction dose at about 2.0 mg/kg.
- Conditions
- Hemodynamic Instability, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- RH (NCT03861377)
- Testing
- Remifentanil R2, Remifentanil R4, Remifentanil R8
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- Helse Fonna
Healthy, COPD
Closing Volume Interpretation and Bronchodilators Effect
The gold standard measures to evaluate small airways (SAW) "in vivo" is not well understood Two tests are today used to measure SAW but real results concordance is not clear These problems have a small evidence Data about real…
- Trial name
- NCT01437748
- Testing
- Indacaterol maleate, Tiotropium bromide
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Milan
Healthy
Comparison of Intramuscular Distribution of Different Injection Volumes Via Diffusion Tensor Imaging (DTI)
The purpose of this experimental pilot study is to assess a positive effect of higher injection volumes of fluid (physiological sodium) in the elbow-flection-muscle (M.
- Trial name
- NCT01162291
- Where
- Austria
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Kirsten Elwischger
Nasopharyngeal Carcinoma
Optimization of Cervical Nodal CTV for Early and Medium Stage NPC
Current radiotherapy guidelines and consensus statements uniformly recommend elective region irradiation (ERI) as the standard strategy for nasopharyngeal carcinoma (NPC).
- Trial name
- NCT05145660
- Testing
- intensity-modulated radiotherapy (IMRT) with reduced-volume, Chemotherapy
- Where
- China
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Yi Junlin
Liver Cirrhosis, Ascites Hepatic
Fresh Frozen Plasma as a Substitute for Albumin in Patients Receiving a Large Volume Paracentesis
Large volume paracentesis with albumin administration is the standard of care for patients with refractory ascites complicating end-stage liver disease.
- Trial name
- NCT03202524
- Testing
- Fresh Frozen Plasma (FFP), Albumin
- Sponsor
- Montefiore Medical Center
Contrast-induced Nephropathy
Predictive Value of CHA2DS2-VASC Score and Contrast Volume to Creatinine Clearance Ratio in Relation to Mehran Score for Contrast-Induced Nephropathy In ST- Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
all patient presented with ST elevated myocardial infarction and underwent PPCI will be calculated with CHA2DS2-VASC score and contrast volume / creatinine clearance as apredictive value for Contrast induced nephropathy and the…
- Trial name
- NCT03266458
- Testing
- Primary percutaneous coronary intervention
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Assiut University
Refractory or Recurrent Ascites
ALFApump System Versus Standard of Care in Ascites Treatment
This is a multicentre, open, randomised, and controlled trial conducted in sixty (60) patients diagnosed with refractory or recurrent ascites.
- Trial name
- NCT01528410
- Testing
- ALFApump removal of ascites, Large volume paracentesis for removal of ascites
- Where
- 7 sites in Austria, France and 3 more
- Volunteers
- 58 people
- Sponsor
- Sequana Medical N.V.
Gastric Emptying, Gastroparesis
Gastric Emptying Recovery After GLP-1 RA Cessation
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can delay gastric emptying and may increase residual gastric contents before general anesthesia.
- Conditions
- Gastric Emptying, Gastroparesis, Preoperative Care
- Trial name
- NCT07360262
- Testing
- Preoperative gastric ultrasound
- Where
- 2 sites in South Korea
- Volunteers
- 186 people
- Sponsor
- Wonkwang University Hospital
Hepatocellular Carcinoma, Metastatic Carcinoma to the Liver
Blood Volume Assessment of Hepatocellular and Metastatic Carcinomas in the Liver
This project investigates the feasibility of assessing the relative blood volume of carcinomas in patients with Hepatocellular Carcinoma (HCC) and liver metastases from pancreatic or colorectal cancer compared to normal liver…
- Trial name
- NCT02288910
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Rush University Medical Center
Adverse Effect
Comparison of Different HES Coload Volumes on the 90% ED of Norepinephrine
The purpose of this study is to investigate the effect of different 6% hydroxyethyl starch (130/0.4) coload volumes on the 90% effective dose of norepinephrine infusion prophylaxis for hypotension during spinal anesthesia for…
- Trial name
- NCT05712018
- Testing
- Hydroxyethyl starch coload - 0 ml/kg, Hydroxyethyl starch coload - 5 ml/kg, Hydroxyethyl starch coload - 10 ml/kg
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University
Macular Degeneration, Diabetic Retinopathy
Iopidine to Decrease Intraocular Pressure Rise After Injections
This is a prospective, randomized, controlled, open-label, single-site investigator-initiated clinical trial. A total of 120 participants will be randomized in a 1:1 ratio either to receive one drop of apraclonidine 1% ophthalmic…
- Conditions
- Macular Degeneration, Diabetic Retinopathy, Retinal Vein Occlusion, Glaucoma
- Trial name
- NCT07891910
- Testing
- Apraclonidine 1.0% ophthalmic solution
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Retina Consultants of Delmarva
Underdosing of Local Anesthetics, Anesthetics, Local
Determination of Minimum Effective Volume of Local Anesthetic in Patients Undergoing Ultrasound-Guided Infraclavicular Approach for Brachial Plexus Blockade
Peripheral nerve blocks with use of USG allowed visualisation of the structures and nerves and made the block administrations safe, quick and comfortable.
- Conditions
- Underdosing of Local Anesthetics, Anesthetics, Local, Peripheral Nervous System Agents, Physiological Effects of Drugs
- Trial name
- NCT03838120
- Testing
- Procedure/Surgery: bupivakain % 0,5
- Volunteers
- 48 people
- Sponsor
- Ankara City Hospital Bilkent
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