Clinical trials: Vomiting
Opioid-Free Anesthesia, Elective Laparoscopic Cholecystectomy
Effect of Opioid-Free Anesthesia (OFA) on Postoperative Pain and Perioperative Nausea and Vomiting in Elective Laparoscopic .
1. To evaluate the efficacy of a standardized multimodal Opioid Sparing (OS) protocol versus conventional opioid-based analgesia in reducing acute postoperative 2.
- Trial name
- OFA (NCT07306910)
- Testing
- opoid free anesthesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Nausea, Vomiting
Postoperative Nausea and Vomiting in Laparoscopic Abdominal Surgery
The goal of this clinical trial is to compare frequency with postoperative nausea and vomiting in ASA( American Society of Anesthesiologists) I, II patients undergoing laparoscopic surgery.
- Trial name
- PONV (NCT05632224)
- Testing
- Aprepitant, Granisetron
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baskent University
Inguinal Hernia
Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine
the study aimed to investigate the effect of Iv nalbuphine on postoperative nausea and vomiting and pain with intrathecal morphine on inguinal hernia repair surgery.
- Trial name
- NCT05704673
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hyperemesis Gravidarum
The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis Gravidarum
Objective: The aim of the researchers is to determine the effects of guided imagery and diaphragmatic breathing exercise application on nausea, vomiting severity, and anxiety level in pregnant with hyperemesis gravidarum.
- Trial name
- NCT05829473
- Testing
- Breathing Exercise Group, Guided Imagery Group
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting (PONV) in Surgical Patients
This study will compare two different drug regimens (oral dronabinol versus intravenous ondanseteron) for the prevention of post-operative nausea and vomiting (PONV).
- Trial name
- PONV (NCT00757822)
- Testing
- Dronabinol, Ondansetron
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PONV, Regional Anaesthesia
Incidence and Factors Associated With PONV in Regional Anaesthesia
Post-operative nausea and vomiting (PONV) is one of the complications associated with surgery and anaesthesia. The main aim of the study is to determine the incidence of post-operative nausea and vomiting among surgical patients…
- Trial name
- NCT03835234
- Where
- Uganda
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Makerere University
Nausea, Vomiting
To Demonstrate the Relative Bioavailability Study of Ondansetron HCl 24 mg Tablets Under Fasting Conditions
To demonstrate the relative bioavailability study of Ondansetron HCl 24 mg tablets under fasting conditions.
- Trial name
- NCT00946387
- Testing
- Ondansetron HCl 24 mg Tablets (Sandoz, Inc.), Zofran (Ondansetron HCl) 24 mg Tablets (GlaxoSmithKline)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sandoz
Chemotherapy-induced Nausea and Vomiting, Nursing Caries
The Effect of Mandala Technique on Acute Nausea-vomiting and Comfort Level in Cancer Patients
Cancer is an important health problem in the world and in our country, and it ranks second among the causes of death in our country (20.7%).
- Trial name
- NCT05885126
- Testing
- MANDALA TECHNIQUE
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ege University
Gum Chewing, Preoperative
Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function
The aim of this study was to investigate the effects of chewing gum before surgery on preoperative anxiety, postoperative gastrointestinal functions (time to first gas, time to first defecation, bowel sounds, abdominal…
- Conditions
- Gum Chewing, Preoperative, Anxiety, Postoperative Nausea and Vomiting
- Trial name
- NCT06603025
- Testing
- chewing gum
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Same-day Discharge, Length of Stay
Preoperative Oral Hydration in the Ambulatory Arthroplasty Population
The purpose of this study is to investigate if the consumption of a complex carbohydrate drink preoperatively, decreases the length of stay and causes for failure to launch in patients undergoing ambulatory total joint…
- Trial name
- NCT05520593
- Testing
- Complex Carbohydrate Drink
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Hypotension, Nausea
Hemodynamic Protection of Preoperative Ondansetron 15 Minutes Before Spinal Anaesthesia in Caesarean Section
Spinal anaesthesia for caesarean section is the most commonly used anaesthetic choice in caesarean deliveries. This is usually associated with maternal hypotension and other adverse side effects.
- Conditions
- Hypotension, Nausea, Vomiting
- Trial name
- NCT04140058
- Testing
- Ondansetron, Normal saline
- Where
- Jordan
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Gynecological Disease
Optimal Haloperidol Dose for Postoperative Nausea and Vomiting Prevention in High-risk Patients
Low-dose haloperidol is known to be effective for the treatment of postoperative nausea and vomiting (PONV). However, precise dose-response studies have not been completed, especially in patients at high risk for PONV who require…
- Trial name
- NCT01639599
- Testing
- Dexamethasone iv injection, Dexamethasone, haloperidol
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Postoperative Nausea and Vomiting (PONV)
Chewing Gum vs. Ondansetron as Rescue Treatment for PONV in Female Patients
The proposed randomized clinical trial aims to test and compare the efficacy of chewing gum vs. Intravenous antiemetic ondansetron as rescue treatment for post-operative nausea and vomiting (PONV) among Lebanese female patients…
- Trial name
- NCT07201883
- Testing
- Ondansetron (Zofran), chewing gum, Ondansetron + Chewing gum
- Where
- Lebanon
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Fasting
The Effects of Carbohydrate-electrolyte Solution on Metabolic Responses in Paediatric Patients
The aim of this study is to evaluate the effects of oral administration of carbohydrate-electrolyte-containing fluid, compared to standard clear fluid during preoperative fasting on metabolic responses, preoperative anxiety and…
- Trial name
- NCT05729100
- Testing
- Oral carbohydrate-electrolyte solution, Control
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Nausea and Vomiting, Chemotherapy-Induced
To Investigate the Effect of Intravenous Ondansetron on Cardiac Conduction as Compared to Placebo and Moxifloxacin in Healthy Adult Subjects
Ondansetron, also known as Zofran, is a marketed compound used for the prevention of nausea and vomiting. This study, called a thorough QT study, will characterize the effects of a single intravenous (IV) dose of ondansetron on…
- Trial name
- NCT01449188
- Testing
- ondansetron, moxifloxacin, saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Postoperative Nausea and Vomiting, Breast Cancer Female
Ramosetron on Late PONV (Postoperative Nausea and Vomiting)
The purpose of this study was to evaluate the effectiveness of additional ramosetron injection for controlling late postoperative nausea and vomiting (PONV) after breast surgery in high risk PONV patients.
- Trial name
- NCT05326360
- Testing
- Ramosetron Hydrochloride
- Where
- South Korea
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Postoperative Nausea, Postoperative Vomiting
The Effects of Acupuncture Against Postoperative Nausea and Vomit After Laparoscopic Cholecystectomy
Postoperative nausea and vomiting (PONV), represents a common condition after surgery and anesthesia. Acupuncture has been used for centuries for analgesia and quality of life improvement in addition to low cost.
- Conditions
- Postoperative Nausea, Postoperative Vomiting, Laparoscopic Cholecystectomy, Acupuncture
- Trial name
- NCT04759079
- Testing
- Acupuncture Needles, Antiemetic Drug
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of West Attica
Nausea, Vomiting
Minimizing Nausea and Vomiting During Spinals for CS
In parturients undergoing Cesarean section under spinal anesthesia, co-loading of 1 liter of crystalloids, with placing the spinal, along with administering a phenylephrine infusion and glycopyrrolate, enables placing a spinal…
- Trial name
- NCT02872935
- Testing
- Glycopyrrolate, Normal Saline
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kokila N Thenuwara
Postoperative Nausea and Vomiting
A Closer Look at the Effect of Dextrose on Postoperative Nausea and Vomiting
"The purpose of this investigator-initiated study is to see if giving dextrose fluid in the veins (IV) decreases the risk of postoperative nausea and vomiting (PONV) in female urologic, gynecologic and breast outpatient surgery…
- Trial name
- NCT01123837
- Testing
- Intravenous fluid, D5LR or lactated ringers
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Morning Sickness
The Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
The primary objective of this study is to compare the efficacy of Bonjesta for the treatment of nausea and vomiting of pregnancy (NVP) in pregnant adolescents aged 12 to 17 years with placebo.
- Trial name
- NCT05289557
- Testing
- Bonjesta
- Where
- 10 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Duchesnay Inc.