Clinical trials: Vulnerable Population
HIV
HIV Testing in Community Health Center Dental Clinics
This is a cluster randomized trial among dental clinics (n=4) to evaluate whether rapid HIV testing (RHT) during dental visits improves HIV testing rates compared to referral for laboratory HIV testing.
- Trial name
- TEETH (NCT07089849)
- Testing
- Rapid HIV testing, Referral for HIV testing
- Where
- 4 sites in United States
- Volunteers
- 6,715 people, healthy volunteers welcome
- Sponsor
- Boston University
Diabetes
Harnessing Health IT for Self-Management Support and Medication Activation in a Medicaid Health Plan
To measure the effects of a Medical health plan-directed automated telephone self-management support system (ATSM) on patient outcomes among ethnically diverse health plan enrollees with diabetes.
- Trial name
- SMARTSteps (NCT00683020)
- Testing
- ATSM Intervention
- Where
- United States
- Volunteers
- 362 people
- Sponsor
- University of California, San Francisco
Head and Neck Neoplasms
Customized Registry Tool for Tracking Adherence to Clinical Guidelines for Head and Neck Cancers
To implement and evaluate a health information technology platform designed to support the management of patients with head and neck cancer in an urban, publicly-funded outpatient setting.
- Trial name
- NCT03546322
- Testing
- Registry
- Where
- United States
- Volunteers
- 802 people
- Sponsor
- University of California, San Francisco
Heart Failure
BioTechCOACH-ForALL: Development of Mental and Physical Exercise Systems, Clinical Recording, Supervisory Analytical Large-scale Data and Virtual Guidance of Vulnerable Population Groups
This would be a single center, parallel, two group randomized controlled pilot study that is designed to assess the feasibility and efficacy of the Virtual Coach Program in elderly patients with heart failure.
- Trial name
- NCT03877328
- Testing
- BiotechCoachForAll
- Where
- 2 sites in Greece
- Volunteers
- 13 people
- Sponsor
- Aristotle University Of Thessaloniki
Diabetic Foot, Educational Intervention
Effectiveness of Educational Intervention on Footcare Among Individuals Having Type 2 Diabetes at Slums of Karachi, Pakistan.
There are multiple studies conducted in Pakistan that supports the topic of foot care knowledge among individual with type 2 diabetes but all are descriptive cross-sectional studies and investigators cannot develop cause effect…
- Conditions
- Diabetic Foot, Educational Intervention, Foot Care, Foot Ulcer, Diabetic
- Trial name
- NCT06358846
- Testing
- Self-care behavior to promote foot care through educational guidance among individual with diabetes
- Where
- Pakistan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SINA Health Education and Welfare Trust
Health Promotion, Vulnerable Populations
Qualitative Study Among Migrant and Socially Vulnerable Populations on Their Interest in Collective Approaches to Health Promotion.
This exploratory qualitative study aims to collect the health needs and representations of migrant and socially vulnerable populations attending the Doctors in the World center in Nice, and to assess their interest in collective…
- Conditions
- Health Promotion, Vulnerable Populations, Access to Health Care
- Trial name
- NCT07174154
- Testing
- Interview
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
COVID-19
Examining How a Facilitated Self-Sampling Intervention and Testing Navigation Intervention Influences COVID-19 Testing
Antigen self-testing kits are more available at this stage in the pandemic, but among vulnerable populations, use is still low and instructions for antigen testing are not typically designed for low health literacy populations.
- Trial name
- NCT05606016
- Testing
- Facilitated Self-Sampling Intervention (FSSI), Testing Navigation Intervention (TNI)., Control
- Where
- 3 sites in United States
- Volunteers
- 1,232 people
- Sponsor
- The University of Texas Health Science Center, Houston
Health Services Research, Prisons, Delivery of Health Care, Vulnerable Populations, Community Health Aides
Evaluation of Transitions Clinic: A Post-Release Clinic for Recently Released Parolees With Chronic Medical Conditions
The purpose of this study is to study the effectiveness of the Transitions Clinic, a post-release clinic for parolees with chronic medical conditions, in achieving increased primary care engagement, lower rates of inappropriate…
- Trial name
- NCT01179035
- Testing
- Transitions Clinic - parolee-targeted care, Expedited Primary Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Transitions Clinic
Heart Failure, Coronary Artery Disease
COVID-19 Testing in Underserved and Vulnerable Populations
As part of National Institutes of Health Rapid Acceleration of Diagnostics-Underserved Populations (RADx-UP) program, the goal of the RADxUP study is to develop, test, and evaluate a rapid, scalable capacity building project to…
- Conditions
- Heart Failure, Coronary Artery Disease, Cancer, Chronic Kidney Diseases
- Trial name
- NCT05315908
- Testing
- Community outreach method
- Where
- United States
- Volunteers
- 9,120 people
- Sponsor
- Jesse Nodora
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Diabetes Learning in Virtual Environments Just in Time for Community Reentry
The proposed study will use a randomized clinical trial design with non-equivalent control group and longitudinal design to evaluate the feasibility, acceptability, and preliminary effects of the Diabetes LIVE JustICE…
- Trial name
- LIVE JustICE (NCT05286892)
- Testing
- Diabetes LIVE JustICE, Enhanced Education
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Louise Reagan
Diabetes Mellitus, Type 2
A Comprehensive Community Approach for Diabetes Prevention and Care for a Vulnerable Population in Galveston
To improve diabetes self-management outcomes, patients with type 2 diabetes (n=150 - aged 13-84) recruited from St. Vincent Clinic (SVC) and Teen Health Center Inc., Clinics will be randomized using block randomization to receive…
- Trial name
- NCT05097534
- Testing
- iDSMES, Standard of Care
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- The University of Texas Medical Branch, Galveston
HIV
Using MOST to Optimize an HIV Care Continuum Intervention for Vulnerable Populations
The present study targets the large population of persons living with HIV/AIDS (PLHA) in the U.S. who are both insufficiently engaged in HIV primary care and not taking antiretroviral therapy (ART), who are mainly African…
- Trial name
- HTH2-MOST (NCT02801747)
- Testing
- Heart to Heart2 (HTH2)
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- New York University
HIV Infections, Sexual Health
Sexual Health of Sub-Saharan African Migrant Women Recently Diagnosed With HIV in Île-de-France: Missed Opportunities for Prevention
This study looks at the sexual health of women from Sub-Saharan Africa who recently found out they have HIV after arriving in Île-de-France.
- Conditions
- HIV Infections, Sexual Health, Migrants, Women's Health
- Trial name
- NCT07011017
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier de Saint-Denis
HIV
Chemsex Health Evaluation With Extended Release System for HIV Treatment
CHEERS is an observational cohort for people living with HIV who are actively practicing chemsex and who are switching to CAB + RPV LA after being virologically suppressed on a stable oral ART regimen.
- Trial name
- CHEERS (NCT06565013)
- Testing
- Cabenuva 600/900, Self administered questionnaires, Semi-directed interview
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Clinique Médicale L'Actuel
Homosexuality, Male, HIV
HIV Prevention Among Vulnerable Male Youth
This exploratory study aims to design and test an HIV prevention intervention for young men who have sex with men (MSM) between the ages of 16-20 as this group comprises the US adolescent population most at-risk for HIV infection…
- Conditions
- Homosexuality, Male, HIV, Substance-related Disorders, Sexual Dysfunctions, Psychological
- Trial name
- NCT01771237
- Testing
- MyPeeps Manualized Group Intervention, Standard Sexual Health Education
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Tobacco Use Disorder
Project 1, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Childbearing Age Women
This study will examine extended exposure to cigarettes varying in nicotine content among disadvantaged women. Disadvantaged women are at increased risk for smoking, nicotine dependence, and using high nicotine yield cigarettes…
- Trial name
- NCT02250534
- Testing
- Very low nicotine content cigarettes
- Where
- 2 sites in United States
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Acute Appendicitis
Non-operative vs. Operative Management of Acute Appendicitis in Vulnerable Patient Populations
The overall project goal is to conduct a pilot randomized clinical trial of operative (laparoscopic appendectomy) vs nonoperative (antibiotic) management of uncomplicated acute appendicitis for vulnerable populations.
- Trial name
- NCT05724628
- Testing
- Laparoscopic appendectomy, Antibiotics (IV transitioned to oral)
- Sponsor
- University of Texas Southwestern Medical Center
HIV, Illicit Drug User
STRIBILD in Non-Nucleoside Resistant Patients (SINNR STUDY)
The SINNR study will evaluate the virologic efficacy (viral load <50 copies/mL)and safety of STRIBILD administered for 48 weeks to HIV-infected current or recent illicit drug users.
- Trial name
- SINNR (NCT02306577)
- Testing
- STRIBILD
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Vancouver Infectious Diseases Centre
COPD
COPD and Socially Vulnerable Individuals
The trial investigates and describes the prevalence of COPD in patients who are in the social nurses' target group and investigates the effect of opportunistic screening for COPD in these vulnerable patients.
- Trial name
- NCT04754308
- Testing
- Spirometry
- Where
- 10 sites in Denmark
- Volunteers
- 513 people
- Sponsor
- Hvidovre University Hospital
Covid19
Treatment for Moderate/Severe COVID-19 in a Fragile and Vulnerable Population, Admitted to a Geriatric Hospital Unit or in a Transicional Care Center
Study to compare the efficacy and safety of colchicine and glucocorticoids compared with the standard of treatment for moderate/severe COVID-19 in a fragile and vulnerable population, admitted to a geriatric hospital unit or in a…
- Trial name
- NCT04492358
- Testing
- Colchicine, Prednisone tablet, standard of care
- Where
- 3 sites in Spain
- Volunteers
- 54 people
- Sponsor
- Maria Joyera Rodríguez