Clinical trials: Vulnerable Populations
Health Disparity, Minority and Vulnerable Populations
Pilot Test of a Mobile App That Helps Spanish-speakers Find Mental Health Services in the US.
The goal of this observational study is to develop and test a mobile app for Spanish speakers residing in the US who seeking drug treatment and/or behavioral health services for themselves or an associate.
- Trial name
- NCT06619431
- Testing
- Mobile Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Volver Health
Parkinson Disease, Parkinsonism
Prodromal and Overt Parkinson's Disease Epidemiological Study in Brazil
Parkinson's Disease (PD) affects people universally, including all ethnic and socioeconomic groups, as a highly prevalent neurodegenerative disorder.
- Trial name
- PROBE-PD (NCT05677529)
- Where
- 4 sites in Brazil
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
HIV Infections, Sexual Health
Sexual Health of Sub-Saharan African Migrant Women Recently Diagnosed With HIV in Île-de-France: Missed Opportunities for Prevention
This study looks at the sexual health of women from Sub-Saharan Africa who recently found out they have HIV after arriving in Île-de-France.
- Conditions
- HIV Infections, Sexual Health, Migrants, Women's Health
- Trial name
- NCT07011017
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Tobacco Use Disorder
Low Nicotine Content Cigarettes in Vulnerable Populations: Opioid Use Disorder
Prevalence of smoking among individuals with opioid use disorder (OUD) is six-fold that of the general US adult population. The mortality rate of opioid-dependent smokers is four times that of opioid-dependent nonsmokers, and…
- Trial name
- NCT04092101
- Testing
- Cigarettes with varying nicotine content, E-Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Critical Illness, Terminal Illness
Prospective National Survey of the Palliative Situation Among Inmates in French Prisons
PARME study had 3 objectives: To identify the specific number of incarcerated individuals with terminal illness in need of palliative care. To describe the health and penal situation of these prisoners.
- Trial name
- PARME (NCT02362295)
- Testing
- qualitative interview
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
COVID-19
Examining How a Facilitated Self-Sampling Intervention and Testing Navigation Intervention Influences COVID-19 Testing
Antigen self-testing kits are more available at this stage in the pandemic, but among vulnerable populations, use is still low and instructions for antigen testing are not typically designed for low health literacy populations.
- Trial name
- NCT05606016
- Testing
- Facilitated Self-Sampling Intervention (FSSI), Testing Navigation Intervention (TNI)., Control
- Where
- 3 sites in United States
- Volunteers
- 1,232 people
- Sponsor
- The University of Texas Health Science Center, Houston
Obstructive Sleep Apnea, Sleep
Impact of Exogenous Ketones on Sleep Apnea
Obstructive Sleep Apnea (OSA) is a common medical disorder that is associated with reduced quality of life and higher risk of cardiovascular disease. Treatments for OSA and limited and not well tolerated.
- Trial name
- KETO-SLEEP 2 (NCT06687655)
- Testing
- Ketone-IQ
- Where
- United States
- Sponsor
- Johns Hopkins University
Diabetes Mellitus, Type 2
A Comprehensive Community Approach for Diabetes Prevention and Care for a Vulnerable Population in Galveston
To improve diabetes self-management outcomes, patients with type 2 diabetes (n=150 - aged 13-84) recruited from St. Vincent Clinic (SVC) and Teen Health Center Inc., Clinics will be randomized using block randomization to receive…
- Trial name
- NCT05097534
- Testing
- iDSMES, Standard of Care
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Coronary Artery Diseases
BIOFLOW-III VIP Russia Registry Orsiro Stent System
Clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES). Along with it, an explanatory (hypothesis-finding) problem will be investigated, whether the patient's body…
- Trial name
- NCT02247492
- Where
- 7 sites in Russia
- Volunteers
- 200 people
- Sponsor
- Biotronik Russia
Viral Hepatitis
Acceptability and Feasibility of Simultaneous Screening for Viral Hepatitis B, C and HIV Among Drug Users and Vulnerable Populations, in Non-conventional Structures "Outside the Walls" by Dual Screening Method RTDs and FibroScan®
The "Scanvir" concept aims to achieve barriers to HCV screening and treating of marginalized patients. The concept is applicable to other various populations and territories and should effectively improve HCV patient's health…
- Trial name
- SCANVIRE2 (NCT06904820)
- Where
- France
- Volunteers
- 2,300 people
- Sponsor
- University Hospital, Limoges
Heathly Subjects, Primary Health Care
Assessing the Effectiveness of Heat Adaptation Digital Messages From Primary Care Providers to Their Patients on the Change in Behaviour for Heatwave-related Preparedness
Extreme heat events pose a significant health threat in Canada, as demonstrated by the 2021 heat wave that claimed over 600 lives in Western Canada. Most heat-related deaths occur indoors and are preventable.
- Conditions
- Heathly Subjects, Primary Health Care, Climate Change, Public Health
- Trial name
- HeatSmart (NCT07024628)
- Testing
- Heat adaptation digital messaging, Non-heat-related digital messaging
- Where
- Canada
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Hopital Montfort
Cervical Cancer, Breast Cancer
Sexual Health Empowerment for Women's Health
The purpose of this study is to expand the reach of an existing cervical cancer literacy and prevention intervention- the Sexual Health Empowerment (SHE) Project .
- Conditions
- Cervical Cancer, Breast Cancer, Contraceptive Usage, Sexually Transmitted Diseases
- Trial name
- SHE-WOMEN (NCT03984695)
- Testing
- SHE-WOMEN
- Where
- United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
HIV Infections
A Simple Intervention to Increase Persistence on PrEP in MSM to Improve Decision Making
Oral HIV pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention modality that requires individuals to take a daily tablet to prevent themselves acquiring HIV.
- Trial name
- NCT06476847
- Testing
- PrEP persistence
- Where
- 2 sites in United States, South Africa
- Volunteers
- 106 people
- Sponsor
- Boston University
Malignant Neoplasm of Large Intestine
Effectiveness of Direct-to-Patient Outreach on Colorectal Cancer Screening Within a Low Income and Diverse Population
The purpose of this study is to determine if the direct mailing of fecal occult blood testing (FOBT) kits to patients who are due for colorectal cancer screening is an effective way to improve colorectal cancer screening rates…
- Trial name
- NCT01385579
- Testing
- Care manager outreach
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Diabetic Foot, Educational Intervention
Effectiveness of Educational Intervention on Footcare Among Individuals Having Type 2 Diabetes at Slums of Karachi, Pakistan.
There are multiple studies conducted in Pakistan that supports the topic of foot care knowledge among individual with type 2 diabetes but all are descriptive cross-sectional studies and investigators cannot develop cause effect…
- Conditions
- Diabetic Foot, Educational Intervention, Foot Care, Foot Ulcer, Diabetic
- Trial name
- NCT06358846
- Testing
- Self-care behavior to promote foot care through educational guidance among individual with diabetes
- Where
- Pakistan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SINA Health Education and Welfare Trust
COVID-19 Pandemic
MiVacunaLA: an Intervention to Improve COVID-19 Vaccination Behaviors Among Latinos
The aim of this study is to determine whether a community-informed, linguistically and culturally tailored educational program delivered via mobile phone is effective in improving vaccination behaviors among Latino families.
- Trial name
- NCT05234372
- Testing
- mivacunaLA
- Where
- 2 sites in United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Diabetes, Cardiovascular Disease
Impact of Patient Activation and Engagement on Patient-Centered Outcomes of Care in ACOs
The investigators will study the delivery of care to patients with diabetes and cardiovascular diseases from 16 practices in health care organizations who receive incentives for improving the quality of patient care.
- Trial name
- ACTIVATE (NCT02287883)
- Testing
- Observational: Patient Activation and Engagement (PAE)
- Where
- 4 sites in United States
- Volunteers
- 2,176 people
- Sponsor
- University of California, Berkeley
COVID-19
Using a Community-level Just-in-Time Adaptive Intervention to Address COVID-19 Testing Disparities
In collaboration with community partners, this study will identify disparities and dynamics of COVID-19 testing and infections in three Texas regions; and implement a multilevel intervention that increases access to testing and…
- Trial name
- NCT05606003
- Testing
- Multi-Level Multi-Component Intervention (MLI), Community Just-In-Time Adaptive Intervention (Community JITAI)
- Where
- 3 sites in United States
- Volunteers
- 1,280 people
- Sponsor
- The University of Texas Health Science Center, Houston
Health Behavior
RCT of Health-promoting Intervention for Older Foreign-born Adults
The overarching aim with this study was to develop, implement and evaluate a health promoting programme for people from Finland or the Western Balkan region, who were 70 years of age or older and independent daily activites (1).
- Trial name
- NCT01841853
- Testing
- Senior meetings
- Where
- Sweden
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Patient Compliance
Improving Comprehensive Cancer Screening Among Vulnerable Patients Using Patient Navigation
Patient navigation (PN) has been shown to improve rates of cancer screening in vulnerable populations. Most cancer PN programs are located in community health centers and focus on a single cancer.
- Trial name
- NCT02553538
- Testing
- Patient Navigation
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital