Clinical trials: Vulvar Disease
Lichen Sclerosus
A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Lichen Sclerosus
The purpose of this study is to evaluate the efficacy and safety of Ruxolitinib cream in participants With Lichen Sclerosus. This is randomized, double-blind, vehicle-controlled (DBVC) study with a DBVC period of 12 weeks…
- Trial name
- NCT05593445
- Testing
- Ruxolitinib cream, Vehicle cream
- Where
- 14 sites in United States, Canada
- Volunteers
- 61 people
- Sponsor
- Incyte Corporation
Vulvar Diseases, Vulvar Atrophy
Vulvar Disease in Nigeria Observational Study
Vulvar disease in Nigeria A look at awareness within patients and health practitioners, self-reported and actual prevalence within communities in Nigeria
- Conditions
- Vulvar Diseases, Vulvar Atrophy, Dermatoses
- Trial name
- VdiN (NCT05890092)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- KDRS ltd
Vulvar Intraepithelial Neoplasia, Genital Warts
SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous Condyloma
This pilot clinical study is to evaluate the efficacy \& safety of SR-T100 gel (2.3% of SM in Solanum undatum plant extract) in patients with VIN(s) or EGW(s).
- Trial name
- NCT01676792
- Testing
- SR-T100 gel with 2.3% of SM in Solanum undatum plant extract
- Where
- Taiwan
- Volunteers
- 29 people
- Sponsor
- National Cheng-Kung University Hospital
Vulvovaginitis, Vaginitis
Vaginal Infection Study
This study will evaluate the efficacy and safety of a vaginal product compared with that of other vaginal products in the treatment of vaginal infections.
- Trial name
- NCT00616330
- Testing
- clindamycin phosphate/butoconazole nitrate, clindamycin phosphate, butoconazole nitrate
- Where
- 133 sites in United States, India and 2 more
- Volunteers
- 1,443 people
- Sponsor
- Lumara Health, Inc.
Chronic Pelvic Pain, Interstitial Cystitis
Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain
We will rigorously test whether modulation of the motor cortex by transcranial direct current stimulation (tDCS) is an effective treatment for patients with chronic pelvic pain through the following specific aims: A) The primary…
- Conditions
- Chronic Pelvic Pain, Interstitial Cystitis, Post Traumatic Stress Disorder, Fibromyalgia
- Trial name
- NCT00554320
- Testing
- tDCS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Summa Health System
Vulvar Cancer, G9a Protein
The Association of G9a Protein and Clinical Outcome of Patients With Vulvar Cancer
To assess the G9a expression in vulvar cancer
- Trial name
- NCT03695809
- Testing
- G9a protein
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Far Eastern Memorial Hospital
Vulvodynia
An Internet-based Information Platform for Vulvodynia Patients
Vulvodynia is a very common but vastly under-diagnosed and under-treated gynaecological condition that leads to extreme suffering for both the women involved but also their partners.
- Trial name
- EMBLA (NCT02809612)
- Testing
- Internet-based platform
- Where
- Sweden
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Vulvar Cancer Stage I, Vulvar Cancer Stage II
A Phase III Randomised Clinical Trial of Ultrasound Groin Monitoring Versus Groin Lymph Node Dissection to De-Escalate the Extent of Surgery in Vulvar Cancer
This study is a phase III, open label, multicentre, three-group, randomised clinical trial. The primary aim of this study is to determine whether intensive groin ultrasound monitoring (1) is effective and safe to replace invasive…
- Conditions
- Vulvar Cancer Stage I, Vulvar Cancer Stage II, Lymph Node Metastasis, Groin Node
- Trial name
- ANVU (NCT06476639)
- Testing
- High-resolution bilateral groin ultrasound monitoring
- Where
- 9 sites in Australia
- Volunteers
- 640 people
- Sponsor
- Queensland Centre for Gynaecological Cancer
Vulvodynia
A Phase 2 Study to Evaluate the Efficacy and Safety of Pudafensine in Vulvodynia (Provoked Vestibulodynia)
The study (IP2015CS05) is a randomised, double-blind, placebo-controlled, 4-way cross-over trial studying the efficacy and safety of single dose administration of pudafensine in vulvodynia (provoked vestibulodynia) patients.
- Trial name
- NCT07391241
- Testing
- Pudafensine
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Initiator Pharma
Vestibulodynia
Long-Term Assessment of Quality of Life and Effectiveness of Onabotulinumtoxina Injections in Provoked Vestibulodynia
The study aims to assess and compare the pain in women suffering from provoked vestibulodynia, before treatment with botulinum injections, 3 months after treatment and 18 months after treatment.
- Trial name
- QUALVESTO (NCT02858375)
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Candidal Vulvovaginitis (ICD-10 Code: B37.3), Vulvovaginal Candidiasis (VVC)
Efficacy and Safety of Clotrimazole+Lactulose Vaginal Suppositories Vs. Clotrimazole Monotherapy in Adult Women with Candidal Vaginitis/Vulvovaginitis
This study aims to compare the efficacy and safety of the combination drug Clotrimazole+Lactulose with the monocomponent product Canesten® (clotrimazole) in adult women diagnosed with candidal vulvovaginitis.
- Trial name
- NCT06835361
- Testing
- Clotrimazole+Lactulose., Canesten (Clotrimazole), Lactulose
- Where
- 7 sites in Belarus, Russia
- Volunteers
- 264 people
- Sponsor
- AVVA Pharmaceuticals Ltd.
Vulvodynia
Physical Therapy as Adjuvant Treatment of Vulvodynia: a Randomized Controled Trial
INTRODUCTION: Vulvodynia (chronic vulvar pain in the absence of clinical findings) has a negative impact over quality of life in women with this diagnose. The existing treatments, however, are manifold but insufficient.
- Trial name
- NCT02871661
- Testing
- Amitriptyline, Kinesiotherapy, IC (Quark)
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- University of Campinas, Brazil
Vulva Cancer
SLN Mapping and ICG Dye for Vulvar Cancer
Doctors typically use blue dye to assist in locating and extracting lymph nodes for biopsy. However, this process can prove somewhat challenging for both patients and medical teams due to its need for extensive coordination and…
- Trial name
- NCT06035068
- Testing
- Indocyanine green
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tufts Medical Center
Human Papillomavirus Associated Carcinomas, Cervical Cancer
SCG142 TCR-T Cells for Human Papillomavirus-Associated Carcinomas
A multicenter, open, single arm dose escalation and dose expansion phase I study to evaluate the safety, tolerability, and efficacy of SCG142 TCR-T cells in Subjects with advanced HPV associated carcinomas.
- Conditions
- Human Papillomavirus Associated Carcinomas, Cervical Cancer, Head and Neck Cancers, Anal Cancer
- Trial name
- NCT06544720
- Testing
- SCG142 TCR-T cells
- Where
- China
- Volunteers
- 18 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Vestibulodynia, Vulvodynia
Savella in Treatment for Provoked Vestibulodynia
The primary aim of this study is to determine the efficacy of milnacipran in reducing pain in women with provoked vestibulodynia (PVD), a centrally mediated pain syndrome similar to fibromyalgia, that is characterized by severe…
- Trial name
- NCT01304589
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Bacterial Vaginosis, Candidiasis
Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments
This randomised controlled trial aimed to verify whether directly observed single dose treatment (with tinidazole+fluconazole) would be as effective as the longer standard treatments (metronidazole for 7 days, plus vaginal…
- Conditions
- Bacterial Vaginosis, Candidiasis, Vaginitis
- Trial name
- NCT00313131
- Testing
- tinidazole+fluconazole vs metronidazole+clotrimazole
- Where
- 7 sites in Ghana, Guinea and 1 more
- Volunteers
- 1,524 people
- Sponsor
- Université de Sherbrooke
Vestibulodynia
Pilot Study to Assess the Efficacy of Cognitive-behavioral Couple Therapy for Provoked Vestibulodynia
The current pilot study aims to assess the feasibility and preliminary efficacy of a novel, 12-week targeted couple intervention (CBCT) for women with vulvodynia and their partners.
- Trial name
- NCT01582373
- Testing
- Cognitive-behavioral couple therapy
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Université de Montréal
Cervical Cancer, Endometrial Cancer
Docetaxel in Treating Patients With Refractory or Recurrent Advanced Gynecologic Cancer
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00287885
- Testing
- docetaxel
- Volunteers
- 18 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Candidiasis, Vulvovaginal, Recurrent Candidiasis of Vagina
The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptoms
The aim of the study is to investigate the efficacy of Fluconazol versus L-Mesitran in the treatment of patients with recurrent vulvovaginal candidiasis. Vaginal swabs will be analyzed after 1, 6 and 12 months.
- Trial name
- NCT05367089
- Testing
- Fluconazole, L-Mesitran
- Where
- 2 sites in Netherlands
- Volunteers
- 252 people
- Sponsor
- Maastricht University Medical Center
Vulvar Pain Symptoms, Vulvodynia (Chronic Vulvar Pain)
To Evaluate if the Medication Gabapentin Lessens Vulvar Pain
The purpose of this research study is to evaluate if the medication gabapentin lessens the vulvar pain some women experience.
- Trial name
- NCT00390013
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Colleen Stockdale