Clinical trials: WOUNDS INJURIES
Knee Dislocation
Compass Hinge Stabilization of Knee Dislocations: A Randomized Trial
The purpose of this project is to evaluate the effect of the Compass™ Universal Hinge external fixator on the outcome of patients following acute dislocation of the knee
- Trial name
- CKH (NCT00582517)
- Testing
- Compass Universal Hinge External Fixator, Non-invasive External Knee Brace
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Radius Fractures, Aged
Cost-effectiveness, Volar Locking Plate or Non-operative Treatment Distal Radius Fracture
A cost-utility analysis based on an earlier published RCT comparing surgery with volar locking plate to non-operative treatment for the elderly with a displaced distal radius fracture.
- Conditions
- Radius Fractures, Aged, Cost-Benefit Analysis, Wrist Fracture
- Trial name
- HE-VOCAL (NCT06067074)
- Testing
- Volar Locking Plate, Plaster Cast
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
Neuropathic Pain, Spinal Cord Injuries
Effects of Hydrotherapy on Neuropathic Pain and Pain Catastrophization in Spinal Cord Injury
Spinal Cord Injury (SCI) is a spinal cord injury of traumatic origin with its main etiology being violence, which constitutes one of the greatest social and health problems worldwide.
- Trial name
- NCT04164810
- Testing
- Hydrotherapy, Physical Therapy
- Where
- Colombia
- Volunteers
- 40 people
- Sponsor
- Universidad del Valle, Colombia
Traumatic Brain Injury
Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury
The CONNECT-TBI Trial aims to develop safe, effective treatments for complex mTBI that improve cognitive functioning. Based on the compelling preliminary data generated by our study team, the objective of this study is to conduct…
- Trial name
- CONNECT-TBI (NCT05236010)
- Testing
- rTMS, HD-tDCS, Attention Process Training
- Where
- 5 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of New Mexico
Rib Fractures
The Erector Spinae Plane Block and Its Effect on Respiratory Status and Pain Management in Rib Fracture Patients
The purpose of this research study is to identify the benefits of a type of nerve block, called an erector spinae plane block (ESP), in the treatment of patients with multiple rib fractures and uncontrolled pain despite receiving…
- Trial name
- NCT03805360
- Testing
- Ropivacaine, Normal Saline Flush, 0.9% Injectable Solution
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Virginia Commonwealth University
Rectal Cancer, Recurrence
Re-irradiation for Pelvic Recurrences in Rectal Cancer Patients
This study investigates the potential benefit of re-irradiation of patients with locally advanced rectal recurrences, by a prospective phase II clinical, imaging and translational research study.
- Conditions
- Rectal Cancer, Recurrence, Radiation Toxicity
- Trial name
- Re-RAD-I (NCT05816980)
- Testing
- Hyperfractionated external beam radiation
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 16 people
- Sponsor
- Aarhus University Hospital
Anterior Cruciate Ligament Injury
Preemptive Analgesia in Cruciate Reconstruction
The aims of this study was to compare analgesic efficacy of preoperative administration of etoricoxib versus celecoxib for post-operative pain relief after arthroscopic anterior cruciate ligament reconstruction.
- Trial name
- NCT01017380
- Testing
- Celecoxib, etoricoxib
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Prince of Songkla University
Wound; Abdomen, Abdomen, Acute
Direct Resuscitation of the Open Peritoneum
The DROP trial evaluates two ways of treating patients whose abdomens are left open after their abdominal surgery. The current standard of care at Sanford is for patients to have their wound covered with a sterile dressing…
- Conditions
- Wound; Abdomen, Abdomen, Acute, Wound Surgical
- Trial name
- SH DROP (NCT04887480)
- Testing
- Abthera™ Open Abdomen Negative Pressure Therapy Device System, Dianeal PD-2 with 2.5% Dextrose
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Sanford Health
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
Traumatic Brain Injury
Interacting Together Everyday: Recovery After Childhood Traumatic Brain Injury (TBI) "I-InTERACT
The purpose of this study is to test an on-line intervention for families of young children who have experienced moderate or severe traumatic brain injury (TBI).
- Trial name
- I-InTERACT (NCT01056146)
- Testing
- Internet-based Interacting Together Everyday: Recovery After Childhood TBI, Internet Resources Comparison
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Vision Disorder, Stroke
Visual Impairment and Functional Visual Performance Following Acquired Brain Injury: A Cross-Sectional Study
This cross-sectional observational study aims to characterize acquired visual impairment in adults with acquired brain injury and to examine the relationship between objectively identified visual impairment and self-reported…
- Conditions
- Vision Disorder, Stroke, Brain Injuries
- Trial name
- NCT07858708
- Where
- Czechia
- Volunteers
- 108 people
- Sponsor
- Charles University, Czech Republic
Breast Cancer
Phase III Trial Evaluating Radium Bromatum Homeopathic Treatment Efficacy on Radiodermatitis Prevention and Treatment for Breast Cancer Women
Breast cancer is the second most frequent cancer worldwide. Principal therapy consists in radiotherapy, but this technic has sides effects as radiodermatitis, concerning about 90 percent of women treated.
- Trial name
- HOMEORAD (NCT03753776)
- Testing
- Radium bromatum pills, Radium bromatum/Apis mellifica/Belladonna pills
- Where
- France
- Volunteers
- 232 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Orthopedic Disorders, Injury of Anterior Cruciate Ligament
Injection Pressure & Adductor Canal Block
This is a prospective, randomized, single-blinded human clinical trial that will examine how injection pressure influences the spread of a given volume of injectate in the adductor canal, during adductor canal nerve block.
- Trial name
- NCT02563990
- Testing
- High Pressure Injection, Low Pressure Injection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Miami
Distal Radius Fracture
"Supracondylar Radial Nerve Block Guided by Ultrasound Versus Hematoma Block for Analgesic Management in Closed Reduction of Distal Radius Fractures"
Non-surgical treatment with closed reduction and immobilization using a splint or cast is the preferred approach for stable distal radius fractures, particularly in elderly patients.
- Trial name
- NCT06857110
- Testing
- ultrasound-guided supracondylar block of the radial nerve, hematoma block, 5 mg of intramuscular diclofenac
- Where
- Colombia
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario San Ignacio
Shoulder Injuries and Disorders
Usability and Acceptance of a New Robotic Exoskeleton for Shoulder Rehabilitation
The purpose of this pilot study is to validate the safety, reliability and usability of FLOAT medical device, a prototypal robotic system for the rehabilitation of the shoulder, designed and developed in the Rehab Technologies…
- Trial name
- CRMINAIL08 (NCT04758520)
- Testing
- FLOAT upper limb exoskeleton
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Thoracic Fracture, Lumbar Fracture
Effect of Bracing Versus No Bracing in Stable Thoracolumbar Compression and Burst Fractures
Spinal orthoses have been used in the treatment of non-operative thoracic and lumbar fractures with much success. However, there has been increasing questioning as to wether or not the orthotics are necessary to have a good…
- Conditions
- Thoracic Fracture, Lumbar Fracture, Compression Fracture of Thoracic Vertebral Body, Compression Fracture of Lumbar Spine
- Trial name
- NCT03952182
- Testing
- Spinal Orthosis (LSO, TLSO), No orthosis
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- St. Louis University
Nasopharyngeal Neoplasms, Radiodermatitis
Comparison of Efficacy and Safety Between Medical Radiation Protectants (FORRAD®) and Trolamine (Biafine) for the Management of Radiation Dermatitis in Patients With Nasopharyngeal Carcinoma Receiving IMRT
Radiation therapy remains the principal treatment for nasopharyngeal carcinoma (NPC). Although intensity modulated radiation therapy (IMRT) has been widely used in China nowadays, radiation dermatitis is still common.
- Trial name
- NCT02729324
- Testing
- Medical Radiation Protectants (FORRAD®), Trolamine (Biafine)
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Yun-fei Xia
Shoulder Impingement Syndrome
The Combined Effect of Thoracic Manipulation and Instrument-assisted Soft Tissue Mobilization in Patients With Shoulder Impingement Syndrome
This study will be conducted to investigate the combined effect of thoracic manipulation and instrument-assisted soft tissue mobilization in patients with shoulder impingement syndrome
- Trial name
- SIS (NCT07800559)
- Testing
- conventional physical therapy, thoracic manibulation, instrument assisted soft tissue mobilization
- Volunteers
- 80 people
- Sponsor
- Cairo University
Injuries
Efficacy of Neuromuscular Training in Youth Soccer Players
Soccer stands as one of the most widespread sports that ensures active participation . It has continued to grow and develop since its inception in all societies
- Trial name
- NCT06203379
- Testing
- Neuromuscular Exercise Training, control exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Traumatic Brain Injury
VR-based EF Rehabilitation for Pediatric TBI
Childhood traumatic brain injury (TBI) poses significant impairment in children's executive functions (EFs) for moderate to severe injuries, yet interventions specifically designed for children's EF rehabilitation post-TBI and…
- Trial name
- NCT03611062
- Testing
- VR Executive Functions Training
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Massachusetts, Lowell
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