Clinical trials: WOUNDS INJURIES
Rotator Cuff Injury
Liposomal Bupivacaine in Rotator Cuff Repair
To assess the efficacy of interscalene liposomal bupivacaine in controlling postoperative pain scores, oral morphine equivalents and sleep quality after arthroscopic rotator cuff repair surgery as compared to interscalene…
- Trial name
- NCT03738696
- Testing
- Exparel, Ropivacaine
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Alabama at Birmingham
Ankle Fractures
Comparison of the Results of Complex Ankle Fractures Treated With and Without Ankle Arthroscopy
Background: An anatomical reconstruction of ankle congruity is an important prerequisite in the operative treatment of acute ankle fractures.
- Trial name
- NCT02449096
- Testing
- Arthroscope, No arthroscope
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Ludwig-Maximilians - University of Munich
User of an Upper Limb Assistance Device, User Experience
Impact Study on Users of Upper Limb Assistive Devices
This impact study of upper limb (UL) assistance devices is part of the Exploratory PEPR O2R "Robotic assistance for human movements." The integrated project PI3 "ASSISTMOV," composed of a multidisciplinary team in engineering and…
- Conditions
- User of an Upper Limb Assistance Device, User Experience, Post-stroke, Spinal Cord Injury
- Trial name
- AMUSE (NCT07429188)
- Testing
- interviews and questionnaires
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Association APPROCHE
Pseudoarthrosis
Clinical Trial Based on the Use of Mononuclear Cells From Autologous Bone Marrow in Patients With Pseudoarthrosis
The purpose of this clinical trial is to check the non-inferiority and lower morbidity of the use of bone marrow mononuclear cells seeded onto a porous matrix of calcium phosphate, for the consolidation of tibial bone defects…
- Trial name
- NCT01813188
- Testing
- ABM seeded onto a porous TCP and DBM, autologous bone graft
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Biting, Chewing Problem
Biting Force and Chewing Efficiency of Complete Dentures.
The aim of this study was to compare the MBF and chewing efficiency of complete denture bases fabricated by conventional, 3D printing and milling techniques.
- Trial name
- NCT04793503
- Testing
- conventional complete denture, CADCAM 3D printed denture, CAD/CAM milled denture
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Epicondylitis, Lateral Humeral
Micronized Dehydrated Human Amniotic Membrane Suspension in the Treatment of Lateral Epicondylitis
The purpose of this study is to determine whether micronized dehydrated human amniotic membrane (dHACM) suspension is more effective in reducing inflammation than conservative measures alone when used to treat acute/early lateral…
- Trial name
- NCT01921569
- Testing
- Standard of Care Therapy, dHACM Injection, Normal Saline Injection
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- MiMedx Group, Inc.
Radiotherapy Side Effect
Evaluation of Music on the Level of Anxiety Felt During External Radiotherapy Sessions
This is a prospective study with a historical comparator. Each of the prospective study endpoints will be compared to data collected retrospectively in patients treated with radiation therapy prior to the implementation of the…
- Trial name
- MUSIC-RT (NCT05289505)
- Testing
- MUSIC-CARE
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Center Eugene Marquis
Anterior Cruciate Ligament Tear
Primary Anterior Cruciate Ligament Repair With and Without Lateral Extraarticular Tenodesis
The investigators aimed to compare the clinical results of primary repairs and Lateral Extraarticular Tenodesis applied with primary repairs in the treatment of proximal ACL tears.
- Trial name
- NCT05923710
- Testing
- Primary anterior cruciate ligament repair, Primary anterior cruciate ligament repair and lateral extraarticular tenodesis (LET) with iliotibial band
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Rotator Cuff Injury
Biceps Lasso Loop and Self- Locking Tenodesis Alongside Repair of Rotator Cuff Tears: Randomised Controlled Trial Study Protocol (BLAST 1)
The aim of this study is to compare the clinical results and complications of self-locking biceps tenodesis and double 360 lasso loop biceps tenodesis for the treatment of long chief of biceps or superior labrum…
- Trial name
- BLAST 1 (NCT06774820)
- Testing
- self-blocking tenodesis, arthroscopic tenodesis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Clinique Générale dAnnecy
Burns
Safety and Efficacy Study of Fibrin Sealant (FS 4IU) for Skin Graft Fixation and Wound Healing in Subjects With Burn Wounds
The purpose of this study is to assess if Fibrin Sealant 4IU is as safe and efficacious as staples (the current standard of care) to achieve fixation of skin grafts and wound healing in subjects with burn wounds.
- Trial name
- NCT00161759
- Testing
- Sheet skin grafts affixed with Fibrin Sealant (lyophilized) with 4 IU/mL Thrombin
- Where
- 12 sites in United States
- Volunteers
- 40 people
- Sponsor
- Baxter Healthcare Corporation
Post-Concussion Syndrome
Interest of the 7 Tesla MRI in the Diagnosis of Post-concussion Syndromes Among Patients With Mild Traumatic Brain Injury
We aimed to conduct a prospective longitudinal interventionnal monocentric study to assess the ability of seven tesla MRI to detect diffuses axonal lesions in patients presenting a post concussional syndrom (PCS) at seven days…
- Trial name
- SPIN (NCT04982562)
- Testing
- 7T MRI
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Poitiers University Hospital
Spinal Cord Injury
fMRI In Spinal Cord Injury Patient After Rehabilitation
The purpose of this study was to evaluate the potential reorganization in the sensorimotor cortex in spinal cord injury (SCI) patients after Body Weight Supported Treadmill Training (BWSTT) associated with conventional motor…
- Trial name
- NCT02074670
- Testing
- Treadmill gait training
- Where
- Brazil
- Volunteers
- 7 people
- Sponsor
- University of Nove de Julho
Drug/Agent Toxicity by Tissue/Organ, Lung Cancer
Amifostine to Prevent Side Effects in Patients Who Are Receiving Chemotherapy and Radiation Therapy for Limited-Stage Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Drugs such as amifostine may protect normal cells from the side effects of chemotherapy and radiation…
- Conditions
- Drug/Agent Toxicity by Tissue/Organ, Lung Cancer, Radiation Toxicity
- Trial name
- NCT00003583
- Testing
- amifostine trihydrate, cisplatin, etoposide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Shoulder, Rotator Cuff Disease
Which is the Most Reliable Radiologic Examination for the Diagnosis of Rotator Cuff Tendon Tear?
At this point in time the approach to the diagnosis of rotator cuff tendon tears is not consensual. The French surgeons, considering they have a good experience of this method, preferably use a shoulder CT-arthrography.
- Trial name
- COIFFE (NCT00925366)
- Testing
- Imaging Procedure
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rotator Cuff Tears
Measuring Opioid Use After Rotator Cuff Repair: Comparing the Effects of Standard vs. Extended-release Nerve Blocks
The investigators aim to determine if a longer acting nerve block, which is a local anesthetic, can help reduce opioid use after surgery in patients that are getting rotator cuff repair surgery.
- Trial name
- NCT05482113
- Testing
- Liposomal bupivacaine, Bupivacaine Hcl 0.25% Inj
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Carilion Clinic
Radiation Pneumonitis
The Formulation of Compound Phellinus Igniarius Decoction on Radiation Pneumonitis
The objectives of this clinical trial were to determine the radioprotective effects and underlying biological mechanisms of Phellinus igniarius and its active components during radiotherapy in patients with thoracic malignant…
- Trial name
- NCT06861179
- Testing
- The formulation of Compound Phellinus igniarius decoction
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhejiang Cancer Hospital
Breast Cancer
Acute Exercise Cardioprotection From Doxorubicin
In rodents, a single bout of exercise prior to injection of a chemotherapy agent used to treat breast cancer prevents or attenuates a number of markers of cardiac injury.
- Trial name
- NCT02006979
- Testing
- exercise
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of British Columbia
Burn
Alterations in Protein Synthesis Rates of Burn Patients Measured Over Time Using PET Scans
Our specific aim is to gain an understanding of protein synthesis rates in burn patients at various times during their injury and recovery by using PET scans. This will be compared with healthy volunteer controls.
- Trial name
- NCT00253279
- Testing
- PET Scans
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Hip Fractures
Randomized Comparison of 2 Fixation Techniques for Unstable Intertrochanteric Hip Fractures
The purpose of this study is to compare the clinical and radiological outcome of patients that are treated with two different orthopedic implants.
- Trial name
- EMvsIM (NCT00597779)
- Testing
- Dynamic Hip Screw (DHS); Trochanteric Fixation Nail (TFN)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Rudy Reindl
Sarcopenic Obesity, Spinal Cord Injuries
Sarcopenic Obesity in Neurodisabilities
To describe the frequency and thresholds for sarcopenic obesity in neurodisabled persons and the fat and lean mass distribution based on various neurodisabilities
- Conditions
- Sarcopenic Obesity, Spinal Cord Injuries, Stroke, Multiple Sclerosis
- Trial name
- SarcObeNDS (NCT03863379)
- Testing
- whole body DXA
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dionyssiotis, Yannis, M.D.
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