Clinical trials: Wait-List Control
Sexual Risk Behavior for HIV-Infection
Effect Study of a Theory-Based Internet Intervention on Safe-Sex Practices
The purpose of this study is to examine the efficacy of a theory based, online tailored intervention on stimulating safe-sex practices among men who have sex with men (MSM).
- Trial name
- NCT00378885
- Testing
- Cognitive-behavioral tailored intervention
- Where
- Netherlands
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Public Health Service of Amsterdam
Mental Health, Psychological Trauma
Pathway-Matched Resilience-Oriented Therapy in Rwanda
This pragmatic, pathway-stratified, cluster-randomized waitlist-controlled trial evaluated Resilience-Oriented Therapy (RoT), a culturally adapted group-based psychosocial intervention for post-genocide Rwanda.
- Conditions
- Mental Health, Psychological Trauma, Stress Disorders, Post-Traumatic, Depression
- Trial name
- RoT-CRT (NCT07621731)
- Testing
- Resilience-Oriented Therapy - Emotion-Regulation Variant, Resilience-Oriented Therapy - Identity-Development Variant, Resilience-Oriented Therapy - Behavioural Self-Management Variant
- Where
- 5 sites in Rwanda
- Volunteers
- 427 people
- Sponsor
- Alexandros Lordos, PhD
Hypertension, Diabetes Mellitus, Type 2
ENCOMPASS: Expansion Study C
Some patients living with multiple long-term health conditions have difficulty accessing the services they need, despite available primary care and community resources.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Chronic Kidney Diseases, Ischemic Heart Disease
- Trial name
- NCT04791267
- Testing
- Community Health Navigator Program
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- University of Calgary
Treatment (ProudMe), Waitlist Control
Dissemination of an Adolescent Obesity Prevention Intervention to Louisiana Schools
This project aims to test the effectiveness and implementation of an adolescent obesity prevention intervention called ProudMe. The study recruits 480 adolescents from 12 middle schools (cluster-randomized to 6 ProudMe schools vs…
- Trial name
- ProudMe (NCT06335056)
- Testing
- ProudMe, Waitlist Control
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Mild Traumatic Brain Injury (mTBI)
Symptom-Targeted Approach to Rehabilitation for Concussion (STAR-C)
Purpose: Investigators propose a three-arm RCT across two military treatment facilities:1) in-person STAR-C, 2) telehealth STAR-C, and 3) no treatment control.
- Trial name
- STAR-C (NCT06855186)
- Testing
- Symptom-Targeted Approach to Rehabilitation for Concussion
- Where
- 2 sites in United States
- Volunteers
- 222 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Intervention, Waitlist Control
Chiropractic T Cell Study
Some studies suggest that specific chiropractic care (techniques known as "spinal manipulation therapy") can have benefits to the immune system but studies are scarce, sample sizes small, and methodology and analyses often not of…
- Trial name
- NCT05412602
- Testing
- full spine corrective protocol
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Type1diabetes
REACHOUT Mental Health Support Mobile App
The purpose of this study is to investigate the effectiveness of participation in a 6-month peer-led mental health support program, delivered via a mobile app (REACHOUT), to adults with type 1 diabetes compared to a wait-list…
- Trial name
- NCT05668507
- Testing
- REACHOUT Virtual Mental Health Support
- Where
- Canada
- Volunteers
- 225 people
- Sponsor
- University of British Columbia
Post Traumatic Stress Disorder
SKY Versus WLC in PTSD
Patients with post traumatic stress disorder (PTSD) will be randomized to a 12-week intervention of Sudarshan Kriya Yoga Trauma Relief Program (SKY) or a wait list control (WLC) to assess the effects of this intervention on…
- Trial name
- NCT02553252
- Testing
- Sudarshan Kriya Yoga Trauma Relief Program (SKY)
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Rotator Cuff Tears
Physiotherapy for Patients Awaiting Rotator Cuff Repair
POWER is a pragmatic multi-centre, external pilot randomised controlled trial with feasibility objectives using a parallel group design with 1:1 allocation ratio and integrated qualitative study.
- Trial name
- POWER (NCT04974242)
- Testing
- Physiotherapist-led exercise
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Headache
Acceptance and Commitment Therapy vs Medical Treatment as Usual Wait-list Control for Primary Headache Sufferers
Research to date suggests that individuals with headache use avoidance as a way to manage their pain. Despite the wide use of avoidance as a coping mechanism of headache triggers, very little empirical evidence exist to support…
- Trial name
- ALGEA (NCT02734992)
- Testing
- ACT+ MTAU, Waitlist Control +MTAU
- Where
- Cyprus
- Volunteers
- 100 people
- Sponsor
- University of Cyprus
Stress, Well-being
Leading Well-being and the Psychosocial Working Environment - A Cluster-randomized Waitlist Controlled Trial
The design comprises a cluster, randomized waitlist controlled design. The goal of the study is to prevent stress and burnout in middle managers and employees in a hospital setting.
- Conditions
- Stress, Well-being, Burn Out
- Trial name
- Matterhorn (NCT05623371)
- Testing
- Training leaders in leading well-being and the psychosocial working environment, The offer of a webinar and written material
- Where
- Denmark
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Depression
Applied Clinical Neuroscience Care for Self-reported Symptoms of Depression and Cerebellar Function in Adults
Pilot study design that operationalizes the multimodal manner of care while evaluating changes in depression symptoms, dysmetria, and balance for medication non-responders.
- Trial name
- DEP (NCT03997240)
- Testing
- Chiropractic Applied Clinical Neuroscience
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Life University
Insomnia Chronic, Insomnia Disorder
Digital CBT-I for Chronic Insomnia
This study evaluates the effectiveness and safety of a digital Cognitive Behavioral Therapy program for Insomnia (CBT-I) in individuals with chronic insomnia.
- Trial name
- NCT06695000
- Testing
- digital CBT-I
- Where
- 5 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- WELT corp
Major Depressive Disorder
Mindbeacon Therapist Assisted Internet Delivered CBT for Depression
Utilization of therapist Assisted internet-delivered cognitive behavioural therapy (TAiCBT) for treating depression and anxiety disorders in stepped-care models, such as the UK's Improving Access to Psychological Therapies (IAPT)…
- Trial name
- NCT05134103
- Testing
- Mindbeacon Therapist Guided, Internet Cognitive Behavioral Therapy for Depression, Waitlist Control Group
- Sponsor
- Ontario Shores Centre for Mental Health Sciences
Chronic Disease, Cancer
Evaluation of the Effectiveness and Implementation of the BETTER Women Peer Health Coaching Program
The Building on Existing Tools To improvE cancer and chronic disease pRevention and screening in primary care (BETTER) Program allows patients in primary care to have a dedicated visit with a prevention practitioner to discuss…
- Trial name
- NCT04746859
- Testing
- Prevention Visit, Peer health coaching
- Where
- 3 sites in Canada
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Osteoarthritis (Knee), Arthroplasties, Knee Replacement
Feasibility of Good Boost+ for Adults Awaiting Total Knee Replacement
The goal of this randomised controlled feasibility trial is to find out whether it is possible to run a larger study of the Good Boost+ community based rehabilitation programme for people waiting for a primary total knee…
- Trial name
- NCT07532785
- Testing
- Good Boost+, Usual NHS Care
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- King's College Hospital NHS Trust
Mindfulness-Based Stress Reduction (MBSR), Cancer
The eCALM Study - An Online Mindfulness-Based Stress Reduction Program for Individuals Living With Cancer in Alberta
For people with cancer, in-person Mindfulness-Based Stress Reduction (MBSR) participation can decrease stress symptoms, mood disturbance, and fatigue, as well as enhance personal growth and spirituality, and improve quality of…
- Trial name
- eCALM (NCT01476891)
- Testing
- Immediate MBSR, Wait-list Control Group.
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Alberta Health services
Major Depressive Disorder
Waitlist-Control Trial of Smartphone CBT for Major Depressive Disorder (MDD), Withdrawn
The investigators are testing the efficacy of Smartphone-delivered cognitive behavioral therapy (CBT) treatment for major depressive disorder (MDD).
- Trial name
- NCT03769350
- Testing
- Smartphone-delivered CBT for MDD
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Achromatopsia
Safety and Efficacy of rAAV.hCNGA3 Gene Therapy in Patients With CNGA3-linked Achromatopsia
The purpose of this study is to proof the safety and efficacy of a single bilateral subretinal injection of rAAV.hCNGA3 in adult and minor patients with CNGA3-linked achromatopsia.
- Trial name
- Colourbridge (NCT02610582)
- Testing
- rAAV.hCNGA3
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- STZ eyetrial
Intervention, Waitlist Control
Qigong and Executive Attention in Older Adults with Depressive Symptoms
The goal of this randomized controlled trial is to test whether executive attention unpacks the antidepressant effect of Baduanjin (a form of health qigong) in older adults.
- Trial name
- NCT06852417
- Testing
- Health qigong training
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University