Clinical trials: Walking, Difficulty
Walking, Difficulty, Mobility Limitation
Testing Interventions for Mobility Through Exercise (TIME)
In this project, the team plans to test the impact of FAST, its brief home-based strength training program which includes performance goal setting, to a program for home (BAND TOGETHER) that is similar to one offered by Silver…
- Trial name
- TIME (NCT05725564)
- Testing
- FAST (Functional Activity Strength Training), Band Together, Behavioral Change Technique
- Where
- United States
- Volunteers
- 702 people
- Sponsor
- Milton S. Hershey Medical Center
Stroke, Chronic Stroke
Reflex Excitability in Post-stroke Stiff-Knee Gait
The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT04947865
- Testing
- Peripheral nerve stimulation, Commercial knee brace
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Mobility Disability, Walking Difficulty
Impact of Loss Aversion Messaging and Anticipated Regret for Inaction on Exercise Adherence in Older Adults
The goal of this clinical trial is to learn if messages focused on not losing the functional benefits of exercise can help older adults with walking difficulty continue to exercise regularly.
- Trial name
- NCT07540052
- Testing
- Brief Daily At-Home Strength Training Program, Loss Aversion Messaging, Standard Adherence Reminder Messaging
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Milton S. Hershey Medical Center
Aging Well, Walking, Difficulty
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
To test the hypothesis that home-based leg heat therapy improves functional capacity, vascular function, and exercise hyperemia in older adults.
- Conditions
- Aging Well, Walking, Difficulty, Hyperemia
- Trial name
- NCT05706181
- Testing
- Home-based leg heat therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Peripheral Artery Disease, Peripheral Vascular Disease
Far Red Light to Improve Functioning in PAD
The LIGHT PAD Trial is a Phase II multi-centered randomized clinical trial to collect preliminary data to test whether daily far red light treatment of the lower extremities in people with PAD improves six-minute walk distance…
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
- Trial name
- LIGHT PAD (NCT06165016)
- Testing
- Far red light therapy
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Northwestern University
Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary
Physical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment
Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France.
- Conditions
- Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty
- Trial name
- CMT1A-HOME (NCT07591779)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Peripheral Arterial Disease, Aging
SMART Exercise for PAD
Supervised exercise therapy (SET), consisting of treadmill exercise conducted three times weekly at a center while supervised by healthcare personnel, is first line therapy for people disabled by lower extremity peripheral artery…
- Conditions
- Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
- Trial name
- NCT06032065
- Testing
- Supervised Treadmill Exercise, Home-Based Exercise, Nitrate-rich beetroot Juice
- Where
- 3 sites in United States
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Peripheral Arterial Disease, Aging
Fisetin to Reduce Senescence and Mobility Impairment in PAD
The investigators propose a pilot randomized trial to gather preliminary data to test the hypothesis that Fisetin will reduce abundance of senescent cells in blood, skeletal muscle, and both subcutaneous and inter muscular…
- Conditions
- Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
- Trial name
- FIRST (NCT06399809)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Northwestern University
Peripheral Artery Disease, Peripheral Vascular Disease
ENhancing Exercise With LIGHT to Improve Functioning in PAD
The ENLIGHTEN PAD Trial will collect preliminary data to test whether daily 660 nm light treatment of the lower extremities immediately before home-based walking exercise sessions improves six-minute walk distance at 4-month…
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
- Trial name
- ENLIGHTEN PAD (NCT06399900)
- Testing
- Far red light therapy, Home-based walking exercise
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Northwestern University
Cerebral Palsy, Walking, Difficulty
A Motor Learning Intervention to Target Walking Performance in Ambulant Children With Cerebral Palsy
The goal of this clinical trial is to learn if a new therapy approach to improve walking ability in children with Cerebral Palsy is acceptable to the children and the families in a community setting.
- Conditions
- Cerebral Palsy, Walking, Difficulty, Spastic Diplegia, Hemiplegic Cerebral Palsy
- Trial name
- MOBILE (NCT06454656)
- Testing
- MOBILE
- Where
- Ireland
- Volunteers
- 14 people
- Sponsor
- Royal College of Surgeons, Ireland
Stroke, Physical Inactivity
How Stroke Affects Leg Muscles When Walking
Stroke is the leading cause of acquired disability in France and the third leading cause worldwide. This research will : Test how reliable current medical methods are for measuring muscle activity.
- Conditions
- Stroke, Physical Inactivity, Spasticity, Muscle, Walking, Difficulty
- Trial name
- MCOACT (NCT07504627)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Limoges
Stroke, Stroke Rehabilitation
Biomarkers of Reaction To HIIT Exercise
Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy.
- Conditions
- Stroke, Stroke Rehabilitation, Lower Extremity Weakness, Spastic, Walking, Difficulty
- Trial name
- BReaTHE (NCT06059872)
- Testing
- High Intensity Interval Training (HIIT)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development
Stroke, Neurological Diseases or Conditions
Development and Efficacy of a Novel, Cost-Effective Gait Training Device Utilized at Home for Stroke Survivors
This pilot, parallel-group randomized controlled trial will evaluate the feasibility, safety, usability, and preliminary efficacy of the Rise\&Walk InHome (RWH), a novel robotic gait training device designed for home use after…
- Conditions
- Stroke, Neurological Diseases or Conditions, Hemiparesis;Poststroke/CVA, Gait Disorders, Neurologic
- Trial name
- NCT07250425
- Testing
- Rise&Walk InHome by Healing Innovations
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Healing Innovations
Aging, Walking, Difficulty
Chronic Wounds and Blood Circulation Detection
Lower limb circulatory insufficiency and the associated chronic wounds are common health problems among the elderly. These issues not only affect the individual's mobility and quality of life but also potentially increase medical…
- Conditions
- Aging, Walking, Difficulty, Chronic Limb-Threatening Ischemia, Chronic Disease
- Trial name
- NCT07330635
- Testing
- Intervention 1: Mixed exercise program, Intervention 2: High-intensity rowing exercise, Intervention 3: Vibration exercise
- Where
- Taiwan
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Fatigue, Walking, Difficulty
Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS
Transcutaneous Electrical Nerve Stimulation (TENS) is a treatment that could potentially reduce walking problems and fatigue in persons with Multiple Sclerosis.
- Conditions
- Fatigue, Walking, Difficulty, Multiple Sclerosis
- Trial name
- NCT06432686
- Testing
- Transcutaneous Electrical Nerve Stimulation, Movement
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Stroke, Walking, Difficulty
To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors
The goal of this clinical trial is to test a gait (walking) training program in non-ambulatory (unable to walk) chronic stroke survivors.
- Conditions
- Stroke, Walking, Difficulty, Cardiovascular Injury
- Trial name
- NCT06247553
- Testing
- Gait Training, Leg Cycling Exercise
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Kansas Medical Center
Walking, Difficulty
Functional Activity Strength Training
This study is a randomized trial of 100 older adults with mobility disability, who performed a similar brief daily, resistance training program.
- Trial name
- FAST (NCT05697497)
- Testing
- Daily exercise intervention
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Milton S. Hershey Medical Center
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Amputation, Surgical, Walking, Difficulty
Outcome of a Cohort of Patients Fitted With a SYME Type Prosthesis in the Context of a Hindfoot Amputation With Distal Support
The purpose of this study is to see outcome of patients with syme prothesis in order to comment the handfoot amputation.
- Trial name
- DEVSYME (NCT06448260)
- Testing
- Questionnary
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Institut Robert Merle d'aubigné
Gait Disorders in Old Age, Gait Disorders, Neurologic
Walking With the SAIRE Smart Walker
The current study aims to investigate the effect of walking with the SAIRE smart walker on spatiotemporal parameters and gait kinematics in a population who suffer from difficulties during gait, and compare this to walking with a…
- Conditions
- Gait Disorders in Old Age, Gait Disorders, Neurologic, Walking, Difficulty
- Trial name
- SAIRE (NCT05461677)
- Testing
- SAIRE smart walker, Standard 4-wheeled walker, No walking aid
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel