Clinical trials: Walking Impairment
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Multiple Sclerosis, Walking Impairment
A Safety and Efficacy Study of ADS-5102 in Patients With Multiple Sclerosis and Walking Impairment
This study assessed the long-term safety and tolerability of ADS-5102 in subjects with MS and walking impairment who had completed the double-blind, placebo-controlled study of ADS-5102 in subjects with MS (ADS-AMT-301).
- Trial name
- NCT03567057
- Testing
- ADS-5102, 274 mg
- Where
- 92 sites in United States, Canada
- Volunteers
- 424 people
- Sponsor
- Adamas Pharmaceuticals, Inc.
Walking Impairment, Multiple Sclerosis
Safety and Efficacy of ADS-5102 in Multiple Sclerosis Patients With Walking Impairment
This study assessed the efficacy and safety of ADS-5102 (at daily doses of 137 mg or 274 mg) compared with placebo in MS patients with walking impairment.
- Trial name
- NCT03436199
- Testing
- ADS-5102, 137 mg, ADS-5102, 274 mg
- Where
- 84 sites in United States, Canada
- Volunteers
- 558 people
- Sponsor
- Adamas Pharmaceuticals, Inc.
Stroke, Stroke, Acute
A Multisite Exploration of Balance Perturbations With and Without Body Weight Support
ZeroG is an FDA-listed robotic body weight support system (BWSS). Mounted on an overhead track, patients are fitted in a harness system tethered to said track, and are able to practice gait and balance activities without the risk…
- Conditions
- Stroke, Stroke, Acute, Balance; Distorted, Balance; Impairment
- Trial name
- NCT05110300
- Testing
- Body weight support system control group, Body weight support system with balance perturbations
- Where
- 4 sites in United States
- Volunteers
- 114 people
- Sponsor
- Gaylord Hospital, Inc
Mobility Limitation, Cognitive Impairment
Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study
Loss of mobility and cognitive ability are serious conditions that threaten the independence of older adults. The objective of this study is to initiate a line of research to develop a novel therapeutic intervention to enhance…
- Trial name
- NCT03122236
- Testing
- Neurorehabilitation of Standard Walking, Neurorehabilitation of Complex Walking, Active Transcranial Direct Current Stimulation (Active tDCS)
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cognitive Impairment, Mild, Cognitive Decline
Efficacy of a Multimodal Brain Health Intervention for Older African Americans
This study tests the feasibility, acceptability, and efficacy of a multimodal intervention (walking, social engagement, and reminiscence), including the use of wearable digital biomarkers, for cognitively healthy and mildly…
- Trial name
- SHARP (NCT04863378)
- Testing
- Walking conversational reminiscence
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Multiple Sclerosis
Locomotor Training in Persons With Multiple Sclerosis
Locomotor training is a new exercise modality that emphasizes task specificity to promote learning and neural plasticity. It has been reported to improve walking in patients with stroke, spinal cord injury and cerebral palsy.
- Trial name
- NCT00607126
- Testing
- Lokomat, resistive training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of California, Los Angeles
Stroke, Gait Impairment
Transcranial Direct Current Stimulation for Post-stroke Gait Rehab
Stroke affects upwards of 800,000 Americans every year and has an enormous impact on the well-being of the American Veteran population with 6,000 new stroke admissions every year.
- Trial name
- NCT03666533
- Testing
- Active transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Lumbar Spinal Stenosis
Lumbar Stenosis Outcomes Research II
The primary objective of the proposed pilot study is to determine the efficacy of oxymorphone hydrochloride and propoxyphene/acetaminophen combination in prolonging the time to onset of pain and reducing the severity of pain…
- Trial name
- LUSTORII (NCT00652093)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Rochester