Clinical trials: Walking Impairment
Multiple Sclerosis
VR and Orthoses for Rehabilitation in Multiple Sclerosis
This non-drug, non-medical device, interventional study explores the feasibility of integrating virtual reality (VR) with wearable sensors to support gait training using a passive orthosis in individuals with multiple sclerosis…
- Trial name
- VIRTUE (NCT07096700)
- Testing
- VR and walking brace-based gait rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 12 people
- Sponsor
- Azienda Usl di Bologna
Mild Cognitive Impairment
Effectiveness of Walking Exercise in Improving Cognitive Function in Older Adults With Mild Cognitive Impairment
The increasing prevalence of mild cognitive impairment (MCI) in our rapidly aging population prompts the need for devising effective interventions to prevent the onset of cognitive impairment and delay its progression to…
- Trial name
- NCT04515563
- Testing
- Stretching exercise, Low-frequency, moderate-intensity walking group, High-frequency, moderate-intensity walking group
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Gait Impairment in Stroke Patients
Spatiotemporal Gait Parameters of Healthy and Stroke Patients During Overground, Treadmill, and Body Weight Supported Treadmill Walking
Gait impairments following a stroke significantly hinder mobility and quality of life, emphasizing the need for precise assessment methods to guide effective rehabilitation strategies.
- Trial name
- NCT07034105
- Testing
- Gait Analysis
- Where
- Bangladesh
- Volunteers
- 25 people
- Sponsor
- Bangladesh University of Engineering and Technology
Lumbar Disc Disease, Lumbar Spine Degeneration
The Six-Minute Walking Test (6MWT) as a Measure of Functional Impairment in Lumbar Degenerate Disc Disease.
The study determines the reliability and validity of the 6-Minute Walking Test (6MWT) in patients with lumbar degenerative disc disease (DDD).
- Conditions
- Lumbar Disc Disease, Lumbar Spine Degeneration, Lumbar Spinal Stenosis
- Trial name
- 6MWT-DDD (NCT03977961)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Cantonal Hospital of St. Gallen
Breast Cancer
Prehabilitation for Breast Cancer Surgery
Prehabilitation for women diagnosed with breast cancer is commonly not part of the clinical pathways as little time (usually a few days) is left between diagnosis and surgery.
- Trial name
- NCT05216302
- Testing
- Group-based Nordic Walking Exercise Program
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Raquel Sebio
Mild Cognitive Impairment, Dual Task
The Activation and Walking Speed of the Prefrontal Cortex of the Elderly Mild Cognitive Impairment During Dual Task.
The goal of this observational study is to compare to investigate the effect of dual task performance on straight and curved walking in elderly people with mild cognitive impairment.
- Trial name
- NCT05885867
- Testing
- Seniors with mild cognitive impairment over 65 years of age
- Where
- South Korea
- Volunteers
- 27 people
- Sponsor
- Sahmyook University
Reaction Time, Physical Fitness
Comparison of Physical Fitness, Walking Speed, Reaction Time In Older Adults With and Without Mild Cognitive Impairment
The aim of the study is to compare physical fitness, walking speed and hand reaction time measurements in older adults with different cognition levels according to the Montreal Cognitive Assessment Scale (MOCA).
- Trial name
- NCT05472727
- Testing
- reaction time test, Physical fitness test
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Heart Failure, Cardiac Failure
Heart Failure Insomnia Treatment Study
The purpose of this study is to compare a short, behavioral treatment for insomnia with sleep monitoring to determine whether these approaches are effective in reducing insomnia and improving sleep quality among patients with…
- Conditions
- Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia
- Trial name
- H-FITS (NCT03636880)
- Testing
- Brief treatment for Insomnia, Sleep Monitoring
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Ohio State University
Mobility Impairments, Walking Aid Users
Evaluating the Effectiveness of Video-based Apps in Healthcare
The goal of this clinical trial is to understand the effectiveness of a novel video-feedback based mobile application that teaches walking aid skills to current or anticipated walking aid users.
- Trial name
- NCT07434570
- Testing
- Walking Aid Skills App, Attentional Control
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Calgary
Peripheral Arterial Disease, Aging
Fisetin to Reduce Senescence and Mobility Impairment in PAD
The investigators propose a pilot randomized trial to gather preliminary data to test the hypothesis that Fisetin will reduce abundance of senescent cells in blood, skeletal muscle, and both subcutaneous and inter muscular…
- Conditions
- Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
- Trial name
- FIRST (NCT06399809)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Northwestern University
Peripheral Arterial Disease
Locomotion and Global Positioning System in Arterial Disease
The maximal walking distance (MWD) performed on treadmill (TT) remains the gold standard in estimating the walking capacity of patients suffering from peripheral arterial disease (PAD) with intermittent claudication, although…
- Trial name
- Starter-GPS (NCT00485147)
- Testing
- Recording of GPS during a free walking in a public park
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Colorectal Cancer
Developing Risk Prediction Model and Testing the Effect of Dual Task Walking on Improving Cognitive Function in Patients With Colorectal Cancer
The aims of this three-year study are to explore cognitive function under different stages of colorectal cancer (CRC) and its related factors; and understand its disturbance and coping process caused by cancer-induced cognitive…
- Trial name
- NCT04490733
- Testing
- dual-task walking
- Where
- Taiwan
- Volunteers
- 355 people
- Sponsor
- National Taiwan University Hospital
Cognitive Impairment, Dementia
Older Adults With Cognitive Impairment Doing Sit to Stands, Walking in Transitional Care Programs: A Feasibility Study
The goal of this intervention study is to test the effects of a nurse-led mobility intervention (known as the OASIS Walking Intervention (Older Adults performing Sit to Stands and Walking Intervention)) in older adults with…
- Conditions
- Cognitive Impairment, Dementia, Delirium, Functional Decline
- Trial name
- OASIS (NCT06150339)
- Testing
- OASIS Walking Intervention
- Where
- 2 sites in Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Peripheral Arterial Disease
Vitamin D and Walking Ability in Patients With Peripheral Artery Occlusive Disease
The purpose of this study is to determine whether the intake of Vitamin D has a positive effect on walking ability of patients with peripheral artery occlusive disease.
- Trial name
- NCT01559974
- Testing
- Cholecalciferol
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- University Hospital, Basel, Switzerland
Stem Cell Transplantation
Physical Impairments Related to Myeloid and Lymphoid Malignancies
Hematologic malignancies may arise from myeloid and lymphoid blood cells lineages affecting blood, bone marrow and lymph nodes. Accordingly, negative effects of malignancies on body systems vary.
- Trial name
- NCT03699358
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Gazi University
Dementia
Enhancing Mobility and Mental Health in Dementia Patients
This study aims to evaluate the effect of a multidisciplinary six-minute walking group and activities on patients with dementia\'s physical activity levels, mobility, anxiety, and cognitive function.
- Trial name
- NCT06611202
- Testing
- Exercise, Clonazepam
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Oxleas NHS Foundation Trust
Caregiver Burden, Depression
Neighborhood-based Physical and Social Activity for Older Black Caregivers and People Living With Dementia
The Sharing History through Active Reminiscence and Photo-imagery (SHARP) Program engages triads (primary caregiver, person living with dementia, caregiver support person) in walking and social reminiscence, using a group tablet…
- Conditions
- Caregiver Burden, Depression, Cognitive Impairment
- Trial name
- SHARP-CG (NCT05658328)
- Testing
- SHARP - Physical and social activity
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab