Clinical trials: War-Related Trauma
Gulf War Illness
Resistant Potato Starch to Alleviate GWI
Gulf War Illness (GWI) affects an estimated 25-32% of the over 700,000 coalition troops deployed to the Persian Gulf as part of the First Gulf War.
- Trial name
- NCT05820893
- Testing
- Resistant Potato Starch
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- VA Office of Research and Development
PTSD, Depression
Effectiveness of Combined Intervention Approaches in the Treatment of Affective Disorders and Chronic Pain in War Victims
This study will measure the effects of biofeedback supported cognitive behavioral therapy (BF-CBT) and group physiotherapy intervention in victims of torture and massive violence in Kosovo.
- Conditions
- PTSD, Depression, Anxiety, Chronic Pain
- Trial name
- NCT01696578
- Testing
- BF-CBT and group physiotherapy
- Where
- Kosovo
- Volunteers
- 31 people
- Sponsor
- Rehabilitation and Research Centre for Torture Victims
Persian Gulf Syndrome
Exercise and Behavioral Therapy Trial (EBT).
This trial is a study of Gulf War era veterans who have unexplained chronic medical symptoms such as pain, fatigue, and/or cognitive difficulties.
- Trial name
- NCT00007748
- Testing
- Aerobic exercise, Cognitive behavioral therapy
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 1,064 people
- Sponsor
- US Department of Veterans Affairs
Posttraumatic Stress Disorder
Mind-Body Skills Groups for the Treatment of War-Related Trauma in Children in Gaza
The objective of this study is to determine whether participation in a mind-body skills program by war-traumatized children in Gaza will result in improvement of posttraumatic stress symptoms, depression, and decreased…
- Trial name
- NCT01595477
- Testing
- Mind-Body Skills Group
- Where
- Israel
- Volunteers
- 114 people
- Sponsor
- The Center for Mind-Body Medicine
Pain Management, Perioperative Analgesia
From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
To compare the effectiveness of continuous regional anaesthesia with standard pain management strategies for the treatment of acute pain in patients with war-related lower limb trauma.
- Conditions
- Pain Management, Perioperative Analgesia, War-Related Injuries
- Trial name
- CRA-WAR-LIMB S (NCT07474506)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Gulf War Syndrome, Gulf War Illness
Validating Gulf War Illness Blood Biomarkers
The investigators goals are to identify blood lipids/metabolites that correlate with cognitive decline in the presence of the APOE ε4 allele among veterans with GWI.
- Trial name
- NCT05736146
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Roskamp Institute Inc.
Aging, Combat Disorders
Vietnam Era Health Retrospective Observational Study
The Vietnam Era Health Retrospective Observational Study (VE-HEROeS) is a national study on the health and well-being of Vietnam Veterans, including Blue Water Navy Veterans, as well as Veterans who served elsewhere during the…
- Trial name
- VE-HEROeS (NCT02825602)
- Where
- United States
- Volunteers
- 24,306 people
- Sponsor
- Veteran Affairs Office of Patient Care Services
Stress - Prevention of Sleep Disorders, PTSD and Depression
Solomiya App - CBT-based Self-help Intervention
The project aims to investigate the feasibility and acceptability of a smartphone intervention for depressive symptoms and insomnia in people living under prolonged stress due to the ongoing war in Ukraine.
- Trial name
- SOLOAPP-FAIT (NCT07104695)
- Testing
- Solomiya App - CBT-based self-help intervention
- Where
- Ukraine
- Volunteers
- 80 people
- Sponsor
- Solveig Kemna
Gulf War Illness
Effects of Botanical Microglia Modulators in Gulf War Illness
The overall objective of this protocol is to test if Gulf War Illness (GWI) involves chronic inflammation that cannot be measured with typical techniques.
- Trial name
- NCT02909686
- Testing
- Boswellia Serrata, Curcumin, Epimedium
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Alabama at Birmingham
Fibromyalgia, Persian Gulf Syndrome
Effects of Low Dose Naltrexone in Fibromyalgia
Low Dose Naltrexone (LDN) has been reported anecdotally to reduce the symptoms of Fibromyalgia, a Chronic Multisystem Illness. The drug may work by regulating natural pain-reducing systems.
- Trial name
- NCT00568555
- Testing
- Low Dose Naltrexone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Stanford University
Gulf War Syndrome, Persian Gulf Syndrome
Coenzyme Q10 for Gulf War Illness: A Replication Study
The purpose of this study is to assess whether a high quality preparation of ubiquinone (coenzyme Q10) benefits symptoms, function, and quality of life in veterans with Gulf War illness.
- Conditions
- Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorder, Respiratory Chain
- Trial name
- NCT06515184
- Testing
- PharmaNord Bio-Quinone Active CoQ10 Gold 100mg
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of California, San Diego
Gulf War Syndrome
Assessing Neuroinflammation in GWI Using MRS
The primary aim of this study is to determine if Gulf War Illness (GWI) likely involves neuroinflammation. The investigators hypothesize that GWI involves neuroinflammation.
- Trial name
- NCT04638998
- Testing
- Magnetic Resonance Spectroscopic Imaging, Blood draw
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Persian Gulf Syndrome, Occupational Exposure
Investigate Olfactory Functioning as a Possible Proxy for Neurotoxic Exposure in Cohorts of Deployed and Non-Deployed Gulf War-Era Veterans.
Significant subsets of military veterans have reported such health problems as headache, joint pain, fatigue, and memory/concentration difficulties subsequent to their participation in the Gulf War.
- Trial name
- NCT00007514
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Post-Traumatic Stress Disorder
KIDNET Versus Meditation/Relaxation - a Dissemination RCTT for Children in Sri Lanka Traumatized by the War and the Tsunami
The purpose of this study is to assess the efficacy of KIDNET versus a Meditation/Relaxation protocol in treating traumatized children in Sri Lanka when applied by locally trained teacher counsellors.
- Trial name
- NCT00820391
- Testing
- KIDNET, Meditation-Relaxation
- Volunteers
- 31 people
- Sponsor
- University of Konstanz
TBI (Traumatic Brain Injury), Cognitive Symptoms
Cognitive Rehabilitation for Victims of War and Related Traumas With Traumatic Brain Injury and Cognitive Impairment
Researchers at Massachusetts General Hospital are looking to see if a program created to help improve thinking and memory can work for people affected by trauma, including asylum seekers and refugees, survivors of intimate…
- Trial name
- NCT06839079
- Testing
- A Trauma-informed, Paraprofessional Delivered Virtual Cognitive Rehabilitation Program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Posttraumatic Stress Disorder
Mind-Body Skills Groups for the Treatment of War-Related Trauma in Adults in Gaza
The objective of this study is to determine whether participation in a mind-body skills program by war-traumatized adults in Gaza will result in improvement of posttraumatic stress symptoms and depression, and will increase…
- Trial name
- NCT01595464
- Testing
- Mind-Body Skills Groups
- Where
- Israel
- Volunteers
- 148 people
- Sponsor
- The Center for Mind-Body Medicine
Perinatal Mental Health, Reproductive Behavior
Women's Reproductive Choices and Mental Health During Pregnancy and After Birth in Wartime Ukraine
The goal of this observational study is to learn how war affects reproductive decisions and perinatal mental health in Ukrainian women.
- Conditions
- Perinatal Mental Health, Reproductive Behavior, Women, Cohort Studies
- Trial name
- NCT07551934
- Testing
- Psychological Assessment, Routine Clinical Data Collection
- Where
- Ukraine
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Taras Shevchenko National University of Kyiv
Traumatic Brain Injury, Post Traumatic Stress Disorder
A Study of Brain Aging in Vietnam War Veterans
Traumatic brain injury (TBI) and post traumatic stress disorder (PTSD) are common combat related problems and may be associated with a greater risk of Alzheimer's disease (AD).
- Conditions
- Traumatic Brain Injury, Post Traumatic Stress Disorder, Alzheimer's Disease, Mild Cognitive Impairment
- Trial name
- DOD-ADNI (NCT01687153)
- Where
- 19 sites in United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Gulf War Syndrome, Gulf War Illness
Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms
This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain.
- Conditions
- Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain
- Trial name
- NCT04182659
- Testing
- Transcranial Magnetic Stimulation
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Veterans Medical Research Foundation
Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma
FMBI With War-affected Families
This study has two central research questions: 1) Is implementing a family mindfulness-based intervention with war-affected immigrant families through community based participatory research methods feasible?; and 2) Does the…
- Conditions
- Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma, War-Related Trauma
- Trial name
- NCT05241314
- Testing
- Learning to BREATHE, After Deployment Adaptive Parenting Tools (ADAPT)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Minnesota