Clinical trials: Water, open to volunteers
Oral Mucosal Disorder
Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa
The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa.
- Trial name
- NCT06942026
- Testing
- Control 1
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
SIAD - Syndrome of Inappropriate Antidiuresis
Urea for Treatment of Hyponatremia in Patients With SIAD Unresponsive to Fluid Restriction
Hyponatremia due to SIAD is frequently insufficiently corrected by fluid restriction alone, which remains the first-line therapy but is often poorly tolerated. Urea supplementation is recommended as second-line therapy.
- Trial name
- UREA-BIVA (NCT07528365)
- Testing
- urea
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Turin, Italy
Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease
Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria
This study evaluates the efficacy of rifampin in the treatment of hypercalcemia and/or hypercalciuria in participants with at least one inactivating mutation of the CYP24A1 gene.
- Conditions
- Idiopathic Infantile Hypercalcaemia - Severe Form, Genetic Disease, Hypercalcemia, Idiopathic, of Infancy, Hypercalciuric Hypercalcemia
- Trial name
- RICHH (NCT03301038)
- Testing
- Rifampin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Philadelphia
Laparoscopic Cholecystectomy, Postoperative Pain
Hot Water Foot Bath for Pain and Gas Relief After Laparoscopic Cholecystectomy
This study investigates the effects of a hot foot bath on postoperative pain and time to first gas release in patients undergoing laparoscopic cholecystectomy.
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain, Gastrointestinal Motility, Postoperative Recovery
- Trial name
- NCT07126223
- Testing
- Hot water foot bath
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Cansu Mert
Hyperkalemia
A Phase 3 Study Evaluating the Efficacy and Safety of WS016 for the Treatment of Hyperkalemia
This clinical trial is an open-label, consisting of 2 phases, corrective phase (CP) and a maintenance phase (MP). The corrective phase aims to correct hyperkalemia within 24 to 72 hours, the maintenance phase aims to maintain the…
- Trial name
- NCT07881965
- Testing
- WS016
- Where
- 50 sites in China
- Volunteers
- 300 people
- Sponsor
- Waterstone Pharmaceutical (Wuhan) Co., LTD.
Nursing Homes Residents, Deterioration, Clinical
Clinical Assessment and Treatment in the Nursing Home as an Alternative to Hospital Admission
This multicenter, cluster-randomized, unblinded quality-improvement study evaluates whether home-based clinical assessment by municipal acute care teams can safely reduce hospital admissions among nursing home residents…
- Conditions
- Nursing Homes Residents, Deterioration, Clinical, Infection, Dehydration
- Trial name
- NCT07756554
- Testing
- Home-based Clinical Assessment and Treatment
- Where
- 4 sites in Denmark
- Volunteers
- 9,000 people
- Sponsor
- Copenhagen University Hospital at Herlev
Chronic Kidney Disease (CKD), Hyperkalemia
Chronic Kidney Disease, Hyperkalemia and Echocardiographic Changes
Patients with CKD ( eGFR \< \<60 mL/min/1,73 m2) presenting to emergency department with isolated hyperkalemia will be study population. Pre and post treatment ECG and echocardiographic findings will be recorded.
- Conditions
- Chronic Kidney Disease (CKD), Hyperkalemia, Hemodialysis
- Trial name
- NCT06635590
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Saglik Bilimleri Universitesi
Degeneration Spine, Cervical Radiculopathy
Salt Water Gargling on Swallowing Following ACDF
The goal of this randomized control trial is to collect sufficient preliminary data on the efficacy of sodium chloride, hereafter referred to as "saltwater" or "saline" in reducing the difficulty of swallowing following…
- Conditions
- Degeneration Spine, Cervical Radiculopathy, Cervical Stenosis, Cervical Spondylosis
- Trial name
- NCT06475365
- Testing
- Sodium chloride gargle
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Muscle Soreness
Cold Vs Warm Water Immersion for DOMS Recovery
The study investigates the effectiveness of physical strategies in addressing Delayed Onset Muscle Soreness (DOMS) in physically active individuals.
- Trial name
- NCT06804564
- Testing
- Cold Water Immersion (CWI), Hot Water Immersion (HWI), Simulated Laser Therapy
- Where
- Poland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Hyperkalemia
A Two-Part, Phase 3 Study Evaluating the Efficacy and Safety of WS016 for the Treatment of Hyperkalemia
This clinical trial consists of 2 parts, Part A and Part B. Part A consists of a 2-day randomized, double-blind, placebo-controlled corrective phase (CP) and a 28-day randomized, double-blind, placebo-controlled maintenance phase…
- Trial name
- NCT07251309
- Testing
- WS016
- Where
- 50 sites in China
- Volunteers
- 420 people
- Sponsor
- Waterstone Pharmaceutical (Wuhan) Co., LTD.
Hamstring Injuries, Hamstring Muscle Repair
Thermal Therapies in the Treatment of Muscle Injuries
Muscle strain injuries represent one of the most prevalent injuries in athletes. Despite this high injury prevalence, there is no evidence to support some of the currently used therapeutic strategies.
- Conditions
- Hamstring Injuries, Hamstring Muscle Repair, Hamstring Muscles, Hamstring Rupture
- Trial name
- NCT07045129
- Testing
- Cold water immersion, Hot water immersion, Physiotherapy only
- Where
- Qatar
- Volunteers
- 135 people
- Sponsor
- Aspetar
Prostate Cancer
Water Vapor Ablation for Grade Group 3 Prostate Cancer
The goal of this study is to evaluate the safety and effectiveness of the Vanquish Water Vapor Ablation System ("Vanquish") in participants with Grade Group 3 (GG3) intermediate-risk prostate cancer.
- Trial name
- VAPOR 3 (NCT07652164)
- Testing
- Water Vapor Ablation
- Volunteers
- 120 people
- Sponsor
- Francis Medical Inc.
Dehydration, Hypovolemia
Validation of a Wearable Bioimpedance Sensor for Hydration Monitoring
The purpose of the project is to validate the performance of a wearable bioimpedance sensor (Re:Balans®) for monitoring hydration status.
- Trial name
- VAMOS (NCT07655401)
- Testing
- Bioimpedance sensor
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Mode Sensors AS
Blood Pressure, Hydration
Potassium, Hydration, Cardiovascular, and Kidney Study (PHACKs)
Compared with White Adults, Non-Hispanic Black Adults are at an elevated risk of developing cardiovascular disease (CVD) and end stage chronic-kidney disease (CKD), two of the leading causes of death in the United States.
- Conditions
- Blood Pressure, Hydration, Vascular Disease Risk
- Trial name
- PHACKs (NCT06062017)
- Testing
- Water and Potassium supplementation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Auburn University
Manual Pressure, Repositioning
Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance
The goal of this trial is to evaluate whether water exchange colonoscopy and CO2-insufflation colonoscopy with an abdominal compression device (Maxbelt me3 type, Nippon Sigmax Co., Tokyo, Japan) can achieve a significantly lower…
- Conditions
- Manual Pressure, Repositioning, Colonoscopy, Colon Polyp
- Trial name
- NCT06496958
- Testing
- CO2 insufflation with an abdominal compression device, Water exchange colonoscopy
- Where
- 2 sites in Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan
Respiratory Aspiration, Hyperglycemia
Maltodextrin Versus Sugar Water Carbohydrate Loading and Gastric Volume in Geriatric Lower Limb Orthopedic Surgery
Before surgery, patients are asked to fast so the stomach is empty and stomach contents cannot enter the lungs during anesthesia. Long fasting is uncomfortable and can raise blood sugar and stress responses in older adults.
- Conditions
- Respiratory Aspiration, Hyperglycemia, Inflammation
- Trial name
- CHO-GERIGAS (NCT07872683)
- Testing
- Maltodextrin carbohydrate drink, Sugar water
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Udayana University
Diarrhea, Respiratory Tract Infections (RTI)
Impact Evaluation of Accelerating Climate-Resilient Water, Sanitation and Hygiene Services for Schools and Healthcare Facilities in Karamoja
Karamoja, in north-eastern Uganda, is among the most water-insecure regions in sub-Saharan Africa. Only 24 per cent of households can access the WHO-recommended 20 litres of water per person per day.
- Conditions
- Diarrhea, Respiratory Tract Infections (RTI), Menstrual Hygiene, Absenteeism
- Trial name
- NCT07823231
- Testing
- Climate-resilient school WASH infrastructure package, WASH and menstrual health capacity building and social and behaviour change package
- Where
- Uganda
- Volunteers
- 16,380 people, healthy volunteers welcome
- Sponsor
- Elijah Kipchumba
Weakness Acquired in the ICU, Muscle Wasting
Muscle and Subcutaneous Tissue Variation by Ultrasound and Impedance Linked to Fluid Balance in ICU Patients
This cross-sectional study aims to investigate the relationship between variations in muscle thickness and subcutaneous tissue, measured by ultrasound, and fluid compartments, evaluated using bioelectrical impedance analysis…
- Conditions
- Weakness Acquired in the ICU, Muscle Wasting, Edema, Fluid Overload
- Trial name
- NCT06697470
- Testing
- Ultrasound and Bioelectrical Impedance Analysis for Muscle Thickness and Fluid Balance Assessment Translation
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Dr F Duprez
Energy
Morning Water Study
This study aims to determine the efficacy of morning water consumption on reducing fatigue and boosting daily productivity. Participants will receive personalized feedback on how their morning hydration influences their energy…
- Trial name
- NCT07256587
- Testing
- Drink 24 ounces of water
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Pregnancy, Gastric Emptying
Gastric Emptying of Water and Sports Drink in Labor
To determine the half time of the emptying of the stomach of women in early labor with and without epidural pain relief when drinking either water or a carbohydrate-based sports drink.
- Trial name
- NCT04229043
- Testing
- Sports drink, Water
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Beth Israel Deaconess Medical Center