Clinical trials: Water-Electrolyte Imbalance
Hypocalcemia After Total Thyroidectomy
The Study of a Safe and Cost-effective Method to Identify Patients at Low Risk of Significant Hypocalcemia After Total Thyroidectomy.
Hypocalcemia is the complication, after total thyroidectomy, that usually determines the length of hospital stay.Serum calcium levels is a quick and cost-effective practice to recognise hypocalcemia in the postoperative follow…
- Trial name
- NCT01027091
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- G. Hatzikosta General Hospital
Hypocalcemia, Parathyroid
Comparing PTeye-assisted Versus Conventional Total Thyroidectomy
This is a prospective, single-blinded, randomized controlled trial to evaluate whether PTeye™ can reduce post-operative hypoparathyroidism (PH).
- Conditions
- Hypocalcemia, Parathyroid, Hypoparathyroidism Post-surgical, Total Thyroidectomy
- Trial name
- NCT07416149
- Testing
- PTeye™ parathyroid detection system
- Where
- Hong Kong
- Volunteers
- 210 people
- Sponsor
- The University of Hong Kong
Vitamin D Deficiency, Hypocalcemia
Effect of Vitamin D Supplement on Disease Activity in SLE
To study the effect of vitamin D supplementation on disease activity of SLE ( SLEDAI-2K ) and IL-6 level
- Conditions
- Vitamin D Deficiency, Hypocalcemia, Hyperparathyroidism, Systemic Lupus Erythematosus (Disorder)
- Trial name
- NCT05260255
- Testing
- vitamin D2 ( calciferol )
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Hypocalcemia, Hypercalcemia
Parathyroid Hormone (PTH) Homeostasis in Bartter Syndrome
Parathyroid hormone (PTH) gland calcium sensing receptor (CASR) regulates PTH secretion. CASR is also expressed in nephron thick ascending limb (TAL).
- Trial name
- NCT01021280
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Hypotension
Efficacy Study of a Facemask Device to Treat Hypotension
The purpose of this study is to determine if the impedance threshold device (ITD) attached to a facemask can increase blood pressure in patients who present to the emergency department with hypotension secondary to hypovolemia.
- Trial name
- NCT00256724
- Testing
- Impedance Threshold Device
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Advanced Circulatory Systems
Dehydration
Kinetic Method to Detect Dehydration
1. The distribution and elimination of infusion fluids can be studied by volume kinetics, a mathematical method based on serial analysis of the blood hemoglobin concentration. 2.
- Trial name
- NCT01062776
- Testing
- Dehydration
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sodertalje Hospital
Primary Adrenal Insufficiency, Intermittent Fasting
Risks of Intermittent Fasting in Patients With Primary Adrenal Insufficiency
In primary adrenal insufficiency, there is an increased risk of hypoglycaemia and dehydration. These risks have been little studied particularly during intermittent fasting.
- Trial name
- NCT06299020
- Testing
- intermittent fasting
- Where
- Tunisia
- Volunteers
- 30 people
- Sponsor
- Hopital La Rabta
Hyperkalemia
The Safety and Tolerability of WS016 in Healthy Chinese Volunteers
This clinic trial evaluates the safety and tolerability of single- and multiple- ascending doses of WS016 in healthy adult participants. There will be about 64 participants,48 active and 16 placebo.
- Trial name
- NCT06281470
- Testing
- WS016 Single Dose(6g), WS016 Single Dose(12g), WS016 Single Dose(24g)
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Waterstone Pharmaceutical (Wuhan) Co., LTD.
Primary Aldosteronism Due to Conn Adenoma, Radiofrequency Ablation Treatment
Radiofrequency Ablation Versus Adrenalectomy for Adenoma in Patients With Primary Aldosteronism and Hypertension
Primary aldosteronism (PA) is characterized by hypertension, frequent hypokalaemia, and an inappropriately high aldosterone-to-renin ratio (ARR).
- Conditions
- Primary Aldosteronism Due to Conn Adenoma, Radiofrequency Ablation Treatment, Adrenalectomy
- Trial name
- ADERADHTA2 (NCT07470580)
- Testing
- RFA -radiofrequency ablation, Adrenalectomy
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Toulouse
Hypomagnesemia, Hypocalcemia
Hypomagnesemia and Hypocalcemia Association Following Thyroidectomy
Magnesium plays a role in the active transport of calcium (Ca+2) and potassium ions across cell membranes. Most of it is intracellular or in the bone , however less than 1% of magnesium is in the blood serum.
- Conditions
- Hypomagnesemia, Hypocalcemia, Hypomagnesemia With Secondary Hypocalcemia
- Trial name
- NCT04351451
- Testing
- thyroidectomy
- Where
- Saudi Arabia
- Volunteers
- 74 people
- Sponsor
- King Saud University
Hypertension, Sodium Excess
Effects of Salt on Serum Osmolarity and Hemodynamics Parameters
Diets containing excessive salt (>12 g/day) have negative effects on kidney and cardiovascular system. Considering this known fact, the investigators aimed to study if the amount of the water taken with excessive salt had any…
- Conditions
- Hypertension, Sodium Excess, Oxidative Stress, Inflammation
- Trial name
- NCT03314727
- Testing
- High salt (NaCl) intake
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Koç University
Hyponatremias, Water Intoxication
"SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia
This study's purpose is to determine whether tolvaptan can safely and effectively return the body's balance of sodium and water toward normal, and to characterize and quantify the potential clinical benefits of this treatment.
- Conditions
- Hyponatremias, Water Intoxication, Inappropriate ADH Syndrome, Water-Electrolyte Imbalances
- Trial name
- NCT00072683
- Testing
- tolvaptan
- Where
- 23 sites in United States
- Volunteers
- 205 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Nocturia
Validation of Capillary Serum Sodium Levels
Prospective interventional study to determine sodium levels in capillary blood via finger prick. The goal is to determine if this technique is suitable and equal to a standard venous blood collection for the analysis of blood…
- Trial name
- NCT05414279
- Testing
- Sodium determination
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Hyperkalemia
SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients
This study aims to compare the effects of Sodium Zirconium Cyclosilicate versus Sodium Polystyrene Sulfonate for treatment of hyperkalemia in patients undergoing regular hemodialysis.
- Trial name
- NCT06029179
- Testing
- sodium zirconium cyclosilicate (SZC), sodium polystyrene sulfonate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University