Clinical trials: Weakness, Muscle
Hip Joint, Muscle Weakness
The Effect High Velocity Low Amplitude Hip Mobilization on Strength in Subjects With Lower Extremity Pathology
Introduction: Lower extremity weakness associated with musculoskeletal pathology can cause activity limitations. Physical therapy intervention in the form of exercise is commonly directed at improving muscular performance…
- Trial name
- NCT03115879
- Testing
- Hip mobilization, Hip manipulation simulation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Muscle Weakness | Patient, Quality of Life
Impact of Underwater Exercise Versus Regular Aerobic Exercise on Quality of Life and Power of Muscle
To investigate the Impact of underwater exercise versus regular aerobic exercise on quality of life and power of muscle
- Trial name
- NCT07132736
- Testing
- Hubbard tank, Mat on the ground
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October 6 University
Sarcopenic Obesity, Muscle Weakness
Mechanisms of Age-Related Muscle Loss
Two independent, but interrelated conditions that have a growing impact on healthy life expectancy and health care costs in developed nations are the age related loss of muscle mass (sarcopenia) and obesity.
- Conditions
- Sarcopenic Obesity, Muscle Weakness, Protein Metabolism Disorder, Physical Activity
- Trial name
- NCT03113279
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Rocuronium, Muscle Weakness
General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery
Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents.
- Conditions
- Rocuronium, Muscle Weakness, General Anaesthesia
- Trial name
- NCT04760912
- Testing
- Rocuronium, General anesthesia for surgery
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Muscle Weakness, Muscle Loss
A Study on the Effects on Glucose Regulation, Inflammation and Serum Lipids After Fish Protein Supplementation in Elderly (GRIPE)
The elderly population have and increased risk of loss of both muscle mass and function and is therefore recommended a higher protein intake than the healthy adult population.
- Conditions
- Muscle Weakness, Muscle Loss, Blood Sugar; High, Inflammation
- Trial name
- GRIPE (NCT03529344)
- Testing
- Blue whiting protein hydrolysate
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Sarcopenia, Muscle Weakness
Functional Changes and Power Training in Older Women.
Extending quality of life and attenuating functional decline is paramount in older adults. This study investigates the effects of low-intensity power-training in older women and its effects on functional outcomes.
- Trial name
- F-POW (NCT02530723)
- Testing
- power training
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Muscle Weakness
Effect of Forward Head and Rounded Shoulder Posture on Hand Grip Strength in Asymptomatic Young Adults
see if there is significant difference between subjects with forward head rounded shoulder posture and subjects with normal posture in hand grip strength in asymptomatic young adults see if there is significant difference between…
- Trial name
- FHRSP-RS-FHP (NCT03586440)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Cairo University
Muscle Weakness
Mitochondria and Muscle Health in Elderly
The aim of this study is to characterize the relation between skeletal muscle mitochondrial metabolism and muscle health in elderly, physically compromised humans.
- Trial name
- ELMIH (NCT03666013)
- Where
- Netherlands
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Healthy Participants
Pain Inhibition With Neuromuscular Electrical Stimulation
The purpose of this study is to demonstrate the pain relieving effect of neuromuscular electrical stimulation that is applied for the purpose of increasing muscle force output.
- Trial name
- NCT05280522
- Testing
- Volitional Contractions (VOL), Neuromuscular Electrical Stimulation (NMES), Noxious Electrical Stimulation (NXES)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New England
Frailty, Muscle Weakness
Effectiveness of Protein Supplementation on Frailty Improvement, Muscle Strength and Physical Performance Among Pre-Frail Elderly People
The goal of this randomized clinical trial is to study the effectiveness of protein supplements in frailty improvement, muscle strength, physical performance, energy intake and body composition of pre-frail elderly people.
- Conditions
- Frailty, Muscle Weakness, Physical Dependence, Weight Loss
- Trial name
- NCT05648617
- Testing
- SUSTINEX Hydrolyzed Whey Protein
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
MULTIPL SCLEROSİS
Comparison of Frailty, Physical Fitness Parameters, and Irisin Levels Between Patients With Multiple Sclerosis and Healthy Volunteers
Multiple Sclerosis (MS) is a chronic immune-mediated and neurodegenerative disease of the central nervous system that often affects young adults and is more common in women.
- Trial name
- NCT07521982
- Where
- Turkey (Türkiye)
- Volunteers
- 782 people, healthy volunteers welcome
- Sponsor
- Baskent University
Oxidative Stress, Inflammation
Oxidative Stress and Nutritional Supplementation Intervention Study
A major means whereby oxidative stress promotes aging-related disease is by activating inflammatory pathways. Decreasing oxidative stress and inflammation should ameliorate many of the problems associated with aging, including…
- Conditions
- Oxidative Stress, Inflammation, Aging, Dementia
- Trial name
- Oxi-Stress (NCT01234506)
- Testing
- secoisolariciresinol diglucoside
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Low Back Pain, Degeneration of Lumbosacral Intervertebral Disc
The Underlying Mechanism of Spinal Manipulative Therapy and the Effect of Pain on Physical Outcome Measures
The purpose of this study is to compare changes in spinal stiffness and back muscle activity between spinal manipulative therapy (SMT) responders, non-responders and asymptomatic participants.
- Conditions
- Low Back Pain, Degeneration of Lumbosacral Intervertebral Disc, Muscle Weakness, Spine Stiffness
- Trial name
- NCT01761838
- Testing
- SMT for low back pain patients, Pain induction (optional), Low back pain participants without SMT
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Muscular Weakness
Enhancing Gluteus Maximus Recruitment
Can participants enhance gluteus maximus recruitment during a single-leg squat test following a neuromuscular training program?
- Trial name
- NCT02042937
- Testing
- Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Aging, Erythrocyte Glutathione Deficiency
Energetics and Function in Older Humans
The investigators have previously reported that older patients with HIV are deficient in glutathione (GSH) due to decreased availability of cysteine and glycine, and that oral supplementation with cysteine (as n-acetylcysteine)…
- Conditions
- Aging, Erythrocyte Glutathione Deficiency, Muscle Weakness
- Trial name
- NCT02348762
- Testing
- Cysteine (as n-acetylcysteine) and Glycine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Bone Density, Muscle Weakness
Whole Body Vibration in Middle Aged Men
This study aims of this clinical trial is to evaluate the effect of an 8-week Whole Body Vibration (WBV) intervention on Bone Mineral Density (BMD), hand grip strength, and vitamin D levels in middle-aged men.
- Trial name
- NCT06644469
- Testing
- Dynatronics VF5 Model vibration platform
- Where
- Saudi Arabia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Jouf University
Muscle Weakness, Osteoporosis, Postmenopausal
Assessing the Effect of Shatavari Supplementation on Bone and Skeletal Muscle Health in Healthy Postmenopausal Women
Shatavari is a plant that grows in Nepal, Sri Lanka, India and the Himalayas and its root has long been used in Ayurvedic medicine.
- Trial name
- NCT05025917
- Testing
- Shatavari, Magnesium stearate
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Low Back Pain, Muscle Weakness
NASM OPT for Pectoral Enhancement and Breast Firmness
This RCT investigates a 12-week NASM OPT program targeting pectoral muscle strength, breast aesthetics (firmness, lift, chest circumference), and low back pain in 120 non-athletic women.
- Conditions
- Low Back Pain, Muscle Weakness, Breast Sagging
- Trial name
- BreastFirmne (NCT06977919)
- Testing
- NASM OPT Program, General Exercise
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Muscle Weakness
Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness
The goal of this trial was to determine if a mid-thoracic high velocity low amplitude spinal manipulation improves force output in those with unilateral hip adductor weakness.
- Trial name
- NCT06534931
- Testing
- High velocity low amplitude thoracic spine manipulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New England