Clinical trials: Weakness, Muscle
Oxidative Stress, Inflammation
Once-Daily Oral Dose of BeneFlax to Healthy Older Adults
The investigators are investigating whether the flax lignan, secoisolariciresinol diglucoside, decreases oxidative stress and inflammation.
- Conditions
- Oxidative Stress, Inflammation, Aging, Pain
- Trial name
- MOD (NCT01846117)
- Testing
- secoisolariciresinol diglucoside, vitamin D
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Muscle Weakness, Muscle Loss
Physical Activity as Intervention Against Age-related Loss of Muscle Mass and Function
A minimum of 450 healthy individuals (62-70 years old) will be recruited. Each individual will be randomized into one of three groups stratified according to gender (M/F), BMI (≤28/>28), and 30 sec chair stand (≤11/>11).
- Conditions
- Muscle Weakness, Muscle Loss, Sarcopenia, Physical Activity
- Trial name
- LISA (NCT02123641)
- Testing
- Heavy resistance training, Moderate intensity training, Control
- Where
- Denmark
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Pelvic Floor Muscle Weakness, Dysmenorrhea
Core Muscle Strength in Women with Primary Dysmenorrhoea
The aim of this study is to compare core muscle strength, core muscle activations, and pelvic tilt angles in women with and without Primary Dysmenorrhea (PD).
- Conditions
- Pelvic Floor Muscle Weakness, Dysmenorrhea, Posture
- Trial name
- NCT06854900
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Derya Azim
IBM, Inclusion Body Myositis
Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body Myositis
This study will evaluate whether neuromuscular ultrasound and MRI can be used as imaging markers of bulbar involvement and swallowing dysfunction in individuals with inclusion body myositis (IBM).
- Conditions
- IBM, Inclusion Body Myositis, Myopathy, Myositis
- Trial name
- NCT07823101
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Carnitine; Muscle, Functional Status
Impact on Functional Status in Older Adults Treated With L-Carnitine
This study evaluates the impact of the treatment with L-Carnitine on the function of adults over 65 years, in conjunction with regular exercise.
- Conditions
- Carnitine; Muscle, Functional Status, Old Age; Debility
- Trial name
- NCT03180424
- Testing
- L Carnitine, Supervised exercise, Exercise at home
- Where
- Uruguay
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de Clínicas Dr. Manuel Quintela
Muscle Weakness, Vitamin D Deficiency
Vitamin D and Physical Performance Before and After Intervention and Birth Outcome in Pregnant Somali and Swedish Women
Somali migrant women, often in veiled clothing, living in a town in mid Sweden on the 60:th parallel were observed to be weak and to have a waddling gate.
- Trial name
- NCT02922803
- Testing
- 1 combination tablet of Vitamin D3/calcium per day, 2 combination tablets of Vitamin D3/calcium per day
- Where
- Sweden
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Strain of Fascia of Intrinsic Muscle of Foot (Disorder), Elastography
Integrated Exercise Therapy Interventions on the Performance and Injury Prevention in Competitive Sports
Football is an increasingly popular exercise and common practice among adolescent and elite athletes. However, these athletes tend to have injuries involving the lower extremity and foot.
- Conditions
- Strain of Fascia of Intrinsic Muscle of Foot (Disorder), Elastography, Muscle Weakness
- Trial name
- NCT04384003
- Testing
- Shear Wave Ultrasound Elastography, The 3-D Motion Analysis, Electromyographic
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Stroke Rehabilitation
Muscle Strength Loss In Stroke Individuals - Control Study
ABSTRACT The muscle strength (MS) is necessary to overcome the resistance encountered during the activity. The present study aims to determine MS loss in stroke individuals (SI).
- Trial name
- NCT04395209
- Testing
- assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Hypermobility, Joint, Muscle Weakness
"Core" Muscle Endurance, Upper Extremity Muscle Strength, Grip Strength, and Hand-eye Coordination in Generalized Joint Hypermobility
Every individual with joint hypermobility may not apply to a health institution because they do not have a complaint that will affect their daily life.
- Conditions
- Hypermobility, Joint, Muscle Weakness, Coordination Lack
- Trial name
- NCT05896722
- Testing
- Core muscle endurance, Upper extremity muscle strength, Grip strength
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Metastatic Cancer, Cachexia; Cancer
Cancer-Associated Muscle Atrophy and Weakness: An Investigation of Etiology
This study is designed to gain a better understanding of the mechanisms leading to muscle wasting and metabolic abnormalities in skeletal muscle of cancer patients.
- Trial name
- NCT03012139
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Intensive Care Unit-acquired Weakness, Artifical Intelligence
AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness
The aim of this observational case-control study is to investigate, whether artificial intelligence can detect ultrasound-derived imaging characteristics typical for intensive care unit-acquired weakness.
- Conditions
- Intensive Care Unit-acquired Weakness, Artifical Intelligence, Ultrasound
- Trial name
- ACTIVATE (NCT06765551)
- Testing
- Neuromuscular Ultrasound
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Anterior Cruciate Ligament Injury, Muscle Weakness
WEakness and Atrophy: isoKinetic With Surface Electromyography Assessment in ACL Surgery
An assessment of the effect of surgical anterior cruciate ligament (ACL) on thigh muscles is critical to the improvement of knee rehabilitation and preservation.
- Trial name
- WEAKNESS (NCT03200678)
- Testing
- isokinetic assessment
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Musculoskeletal Status, Muscle Weakness
Use of Jumping Mechanography as a Method to Assess Musculoskeletal Status in Older Adults
Decline in muscle function may increase risk of hip fracture and decrease quality of life. Different tests are currently used to measure muscle function but they do not work for all individuals.
- Trial name
- NCT00596089
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Muscle Weakness
Magnetic Muscle Stimulation of Abdominal Muscle
Evaluate the safety and efficacy of magnetic muscle stimulation (MMS) of abdominal muscle.
- Trial name
- MMS (NCT04199312)
- Testing
- Magnetic Muscle Stimulation (MMS) device
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Diabetic Peripheral Neuropathy, Diabetes
Diabetes, Falls, and Fractures
Comparing severity of diabetic peripheral neuropathy (small and large fibers including autonomic neuroapthy) to postural control and vestibular measurements
- Conditions
- Diabetic Peripheral Neuropathy, Diabetes, Balance; Distorted, Vestibular Neuropathy
- Trial name
- DIAFALL (NCT05389566)
- Testing
- Quantative Sensory Testing, NCStat-DPN-Check, Composite Autonomic Symptom Score 31
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Sarcopenia, Old Age; Debility
Study of the Validity and Reliability of Two Digital Dynamometers in Older People
It is a cross-sectional, randomized, and single-center study with a duration of 6 months. The study will follow the STROBE guidelines for cross-sectional studies and CONSORT 2024.
- Conditions
- Sarcopenia, Old Age; Debility, Frailty
- Trial name
- SOVARDDIOP (NCT06623019)
- Testing
- Validation and reliability
- Where
- Spain
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Electroacupuncture, Urinary Incontinence
Electroacupuncture Treatment for Urinary Incontinence (UI) in Women
The investigators have developed an investigation comparing electroacupuncture with pelvic floor exercises in female urinary incontinence (UI).
- Conditions
- Electroacupuncture, Urinary Incontinence, Women, Pelvic Floor Muscle Weakness
- Trial name
- ELECAPUN (NCT04842695)
- Testing
- electroacupuncture group
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Neck; Anomaly, Muscle Weakness
Attentional Focus Influence During Cranio-Cervical Flexion Test
The purpose of this study is to termine if a different attentional focus would alter the motor control in cervical muscles during the cranio-cervical test.
- Conditions
- Neck; Anomaly, Muscle Weakness, Muscle Weakness Condition
- Trial name
- NCT03567122
- Testing
- Internal Focus of Attention, External Focus of Attention, Control
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Whiplash Injury of Cervical Spine, Muscle Weakness
Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders
The aim of this prospective observational study is to investigate whether the presence or absence of directional preference impacts movement coordination impairments as measured in patients with Whiplash Associated Disorders…
- Trial name
- NCT06143228
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- D'Youville College
Postpartum, Muscle Fatigue
Muscle Function After Childbirth
This study will evaluate lower extremity and trunk neuromuscular control in 78 nulligravid and postpartum women. Participants will attend two experimental sessions, approximately 1 week apart, to assess neuromuscular function.
- Conditions
- Postpartum, Muscle Fatigue, Force Steadiness, Nulligravid
- Trial name
- NCT05073224
- Testing
- Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task, Lower Extremity Strength Testing
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Carroll University