Clinical trials: Weakness
ICU Acquired Weakness (ICUAW)
Feasibility and Safety of Digital Rehab Platform for Bedridden Patients
Study Title Rehabilitation Program for Bedridden Patients Using Digital Devices Study Purpose This study aims to evaluate the effectiveness of a rehabilitation program using digital devices and apps for bedridden patients in a…
- Trial name
- NCT06849765
- Testing
- Rehabilitation
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Asan Medical Center
Muscle Weakness, Syndrome; Institutionalization
Effects and Costs of Respiratory Muscle Training in Institutionalized Elderly People
The global loss of muscle mass and strength associated with aging is a cause of functional impairment and disability, particularly in the older elderly (>80 years).
- Conditions
- Muscle Weakness, Syndrome; Institutionalization, Respiratory Morbidity, Cardiovascular Morbidity
- Trial name
- NCT01759992
- Testing
- Threshold® Inspiratory Muscle Trainer (treatment).
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- University of Valencia
Neurophysiology, Physiology
Functional Implication of Corpus Callosum in Voluntary Strength in COPD Patients
Patients with COPD have lower capability of activating their muscles. At the cortical level, force production is not only controlled by contralateral primary motor cortex but also by ipsilateral motor cortex.
- Trial name
- NCT03807258
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- 2 sites in France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Weaning Failure
Inspiratory Muscle Training in Difficult to Wean Patients
Prolonged mechanical ventilation secondary to weaning failure demands a significant amount of intensive care unit (ICU) resources, thus increasing the economic burden of public healthcare costs.
- Trial name
- NCT03240263
- Testing
- Inspiratory Muscle Training, Endurance training
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Coxarthrosis, Muscle Weakness
Does Capsulectomy, Performed in Total Hip Arthroplasty With a Direct Anterior Approach Cause Knee Extension Strength Loss?
Total hip arthroplasty (THA) has been successful in relieving pain and restoring function in patients with advanced arthritis of the hip joint.
- Trial name
- NCT04500093
- Testing
- Capsulotomy with Repair, Capsuloectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Critical Illness, Intensive Care Unit Acquired Weakness
Virtual Reality Rehabilitation on the Intensive Care Unit for Critically Ill Patients
Feasibility study of the use of an interactive Virtual Reality device in rehabilitation of critically ill patients on the Intensive Care Unit.
- Trial name
- VRR-ICU (NCT05591248)
- Testing
- VRR
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Spastic Cerebral Palsy, Physical Therapy Modalities
Effectiveness of Whole-Body Vibration
Cerebral Palsy is the most common cause of severe physical disability in childhood and may present difficulties and limitations that will have an impact on their independence and integration in all social areas.
- Conditions
- Spastic Cerebral Palsy, Physical Therapy Modalities, Vibration; Exposure, Lower Extremity Weakness, Spastic
- Trial name
- WBVibration (NCT06330311)
- Testing
- Physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Physiology
Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation
Patients with COPD have lower cortical activation and higher cortical inhibitory levels. The purpose of this study is to test the reversibility the lower cortical activation by counterbalancing the increased cortical inhibitory…
- Trial name
- NCT03368703
- Testing
- Anodal transcranial direct-current-stimulation
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Virtual Reality, Intensive Care Unit Acquired Weakness
The Effects of Virtual Reality in Intensive Care Patients
Weakness of respiratory muscles delays weaning from the ventilator, prolongs hospital stay and increases treatment costs. Conventional treatments for respiratory muscles reverse these negative effects.
- Trial name
- NCT06442254
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istinye University
Rehabilitation
Early Rehabilitation in Critical Illness Survivors
Background: Few studies showed that early rehabilitation on the Intensive Care Unit (ICU) results in a better functional outcome at hospital discharge and reduced hospital stay.
- Trial name
- ER (NCT02754505)
- Testing
- Early rehabilitation, Usual care
- Where
- Austria
- Volunteers
- 53 people
- Sponsor
- Danube Hospital
Stress Urinary Incontinence, Pelvic Floor Muscle Weakness
Effectiveness of Pelvic Floor Muscle and Abdominal Training in Women With Stress Urinary Incontinence
The aim of this study was to investigate the effectiveness of pelvic floor muscle and abdominal training in reproductive-age patients with stress urinary incontinence.
- Trial name
- NCT03401983
- Testing
- Pelvic Floor Muscle Training and Abdominal Training, Pelvic Floor Muscle Training
- Volunteers
- 64 people
- Sponsor
- Trakya University
ICU-weakness
VERARE_2 Efficacy of the Observation of Virtual Motor Actions for the Improvement of Gait in Patients With ICU-weakness
After hospitalization in Intensive Care (Intensive Care Unit or Continuing Care Unit), approximately 50% of patients usually present with intensive ICU-weakness, i.e.
- Trial name
- VERARE_2 (NCT04713345)
- Testing
- Virtual Reality Observations, Relaxation
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Rennes University Hospital
Critical Illness, Old Age; Debility
The Very Old Intensive Care Patient: A Multinational Prospective Observation Study
The primary aim is to document the incidence and short-term outcome of the elderly ICU patient (≥ 80 years) using a multicentre, multi national approach The secondary aim is to investigate the properties of a simple frailty index…
- Conditions
- Critical Illness, Old Age; Debility, Survival
- Trial name
- VIP1 (NCT03134807)
- Testing
- Observation prospective
- Where
- Norway
- Volunteers
- 5,132 people
- Sponsor
- University of Bergen
ICU Acquired Weakness
Early Rehabilitation Using Functional Electrical Stimulation Assisted Supine Cycling in the Intensive Care Unit
Critically ill patients in the intensive care unit are known to lose muscle mass and function at a rapid rate. Currently, there is a global recognition and shift in the ICU culture to reduce sedation and encourage exercise and…
- Trial name
- NCT03554811
- Testing
- Functional electrical stimulation assisted supine cycling (FESC), Conventional early exercise and mobility interventions
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Community Health System
Pelvic Floor Disorder, Pelvic Floor Muscle Weakness
Development & Validation of Pregnancy Specific Pelvic Floor Rehab Protocol
Pelvic Floor Weakness is very common Facing by women during Pregnancy. PFM weakness is recognized as one of the problems encountered in patients with urinary and fecal incontinence which have very negative impact on Quality of…
- Conditions
- Pelvic Floor Disorder, Pelvic Floor Muscle Weakness, Pelvic Floor Muscle Training, Pregnancy
- Trial name
- NCT06875778
- Testing
- Pelvic Floor Exercises
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Riphah International University
Hypertension,, Obstructive Sleep Apnea
Effects of Continuous Positive Airway Pressure and Valsartan Treatments on Arterial Blood Pressure in OSAS Patients
The main objective of the study is to compare the decrease of mean arterial blood pressure over 24 hours in patients having obstructive sleep apnea syndrome and weak or moderate hypertension, treated by Valsartan 160mg per day…
- Trial name
- VALSAS (NCT00409487)
- Testing
- Continuous positive airway pressure (CPAP), Valsartant treatment
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Low Back Pain, Degeneration of Lumbosacral Intervertebral Disc
The Underlying Mechanism of Spinal Manipulative Therapy and the Effect of Pain on Physical Outcome Measures
The purpose of this study is to compare changes in spinal stiffness and back muscle activity between spinal manipulative therapy (SMT) responders, non-responders and asymptomatic participants.
- Conditions
- Low Back Pain, Degeneration of Lumbosacral Intervertebral Disc, Muscle Weakness, Spine Stiffness
- Trial name
- NCT01761838
- Testing
- SMT for low back pain patients, Pain induction (optional), Low back pain participants without SMT
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Hip Osteoarthritis, Osteoarthritis, Hip
Gluteal Sling Release on Gluteal Dysfunction After in Primary Total Hip Arthroplasty
This study investigates the effects of gluteal sling release during total hip arthroplasty (THA) on gluteal muscle function and hip joint performance.
- Conditions
- Hip Osteoarthritis, Osteoarthritis, Hip, Gluteus Maximus Muscle Atrophy, Muscle Weakness Condition
- Trial name
- NCT06850155
- Testing
- Sling release, Sling release and repair
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Ankara City Hospital Bilkent
Intensive Care Unit Acquired Weakness (ICUAW)
eStimCycle: Early Rehabilitation in Critical Care
Project Summary: Patients who have a length of stay four or more days in ICU and requiring mechanical ventilation assistance to breathe for more than 48 hours will be invited to participate.
- Trial name
- eStimCycle (NCT02214823)
- Testing
- FES-Cycling, Standard Care
- Where
- 4 sites in United States, Australia
- Volunteers
- 162 people
- Sponsor
- Associate Professor Sue Berney PhD, BPT
Lung Cancer
Epidemiologic Multicenter Prospective Study in Advanced NSCLC (Non Small Cell Lung Cancer) Patients With PDL1 (Protein Death Ligand 1) Expression.
Epidemiologic multicenter prospective study in advanced NSCLC patients with PDL1 expression : evaluation of clinical and pathological characteristics of PDL1 high expression patients compared to patients with a weak or no…
- Trial name
- EXPLORE-PDL1 (NCT02785562)
- Testing
- Assessment of PDL1 expression
- Where
- 13 sites in France
- Volunteers
- 170 people
- Sponsor
- Groupe Francais De Pneumo-Cancerologie
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