Clinical trials: Weakness
Weakness, Muscle
Effects of INDUS810 on Body Composition, Muscular Performance, and Training Adaptations
The purpose of this 12-week, interventional study is to determine the effects of oral supplementation with Indus810 (dietary supplement with active ingredient Fenugreek) on body composition, muscular performance, and training…
- Trial name
- NCT03850106
- Testing
- Indus810
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Myasthenia Gravis
Exploring Outcomes and Characteristics of Myasthenia Gravis 2
The goal of this prospective observational study is to create a network repository of clinical data and biological samples to help researchers learn more about myasthenia gravis.
- Trial name
- EXPLORE-MG2 (NCT06002945)
- Testing
- Blood sample
- Where
- 10 sites in United States
- Volunteers
- 311 people
- Sponsor
- Yale University
Patellofemoral Pain Syndrome
Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain
Background: Researchers are interested in how the muscles affect the movement of the knee cap. These muscles may be related to different kinds of knee pain that are not caused by an injury or a disease.
- Trial name
- NCT01862731
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Adult Patients, Intensive Care Unit
Functional Recovery Over the First Year After ICU Discharge
Intensive Care Unit Acquired Delirium (ICU-AD) and Intensive Care Unit Acquired Weakness (ICU-AW) are common in critically ill, mechanically ventilated adult patients.
- Trial name
- NCT04206306
- Where
- Taiwan
- Volunteers
- 407 people
- Sponsor
- National Taiwan University Hospital
Breast Cancer
Neurophysiological Evaluation of Training Effect on Cancer-Related Weakness
Breast cancer patients often suffer from long-term physical symptoms of weakness. In this study, investigators propose to compare how two different low intensity physical exercise training programs can improve handgrip strength…
- Trial name
- NCT02844504
- Testing
- Low Intensity Exercise Training 1, Low Intensity Exercise Training 2
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Old Age; Debility
Effectiveness of 8 Week Multicomponent Exercise Program in Older Adults With Frailty and Cognitive Impairment
Multicomponent exercise program in a frail population. It is analyzed whether there is an improvement in different parameters of the daily life of the study subjects, analyzing the variables of: physical condition, fragility…
- Trial name
- GERYPHYSIO (NCT06440733)
- Testing
- Multicomponent exercise program focused in elderly.
- Where
- Spain
- Volunteers
- 17 people
- Sponsor
- University of Malaga
Old Age; Debility
Multicomponent Exercises in Functional Performance and Cognitive Ability of Hospitalized Elderly
Older patients spend most of their time in situations of muscle disuse during acute hospitalization. Physical inactivity is a key factor for the development of adverse events caused by hospitalization, known as iatrogenic…
- Trial name
- NCT05317338
- Testing
- Group-based exercise training during hospitalization
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Atrophy of Rectus Femoris Muscle (Physical Finding)
Relationship Between Protein Intake and ICU Skeletal Muscle Weakness
Muscle wasting is a common finding in critically ill patients and is associated with adverse outcomes. A good strategy for avoiding or decreasing muscle loss is adding adequate quantities of protein to the nutritional therapy…
- Trial name
- NCT06012201
- Volunteers
- 60 people
- Sponsor
- Tufts Medical Center
Diabetic Foot Ulcer, Diabetic Wound
Peer Support for Patients With Diabetic Foot Ulcers
The objective of the study is to develop a peer support program that helps improve ulcer care in patients with a diabetic foot ulcer (DFU).Diabetes, peripheral arterial disease (PAD), foot ulceration, and subsequent amputation…
- Conditions
- Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot
- Trial name
- NCT06004219
- Testing
- Peer counseling group
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Myofascial Pain Syndrome, Muscle Weakness
Gluteus Medius Latent Trigger Point and Muscle Strength in Healthy Subjects
This study aimed to investigate the relationship between latent MTrPs and gluteus medius muscle strength in a group of healthy adults.
- Trial name
- NCT04640558
- Testing
- Muscle strength measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kars State Hospital
Pelvic Floor Muscle Weakness, Pelvic Floor Disorder
Does Hip Strength Impact Active Females Rate of Pelvic Floor Dysfunction? The Primary Goal of This Research is to Collect Data on Hip Strength for Active Females and Assess if There is a Relationship Between Hip Strength and Pelvic Floor Dysfunction (PFD).
The primary goal of this research is to collect data on hip strength for active females and assess if there is a relationship between hip strength and pelvic floor dysfunction (PFD).
- Conditions
- Pelvic Floor Muscle Weakness, Pelvic Floor Disorder, Pelvic Pain, Hip Strength
- Trial name
- NCT07119476
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- George Fox University
Hyperkyphosis, Postural Kyphosis
Video-Based Game Therapy in Thoracic Hyperkyphosis
The scapula provides the base of the kinetic chain, which is stabilized by the surrounding muscles. Considering that activating the scapular musculature to stabilize the spine would restore the relationship between body segments…
- Conditions
- Hyperkyphosis, Postural Kyphosis, Exergaming, Muscle Weakness
- Trial name
- NCT05912478
- Testing
- Videogame-Based Therapy, Waiting list
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University - Cerrahpasa
Ventilator Weaning
Instrumental Respiratory Physiotherapy in Difficult-to-wean ICU Patients
Difficult ventilatory weaning is associated with a 20% mortality rate. 40% of these patients will develop intensive care unit (ICU)-acquired neuromyopathy, associated with reduced cough strength and a 4-fold increase in the risk…
- Trial name
- PHYSIO WEAN (NCT06499389)
- Testing
- Systematic and early intensive instrumental respiratory physiotherapy for patients undergoing difficult ventilatory weaning, Protocolized standard-of-care respiratory physiotherapy
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Frailty Syndrome, Respiratory Muscle Weakness
Longitudinal Ultrasound Assessment of Diaphragmatic and Respiratory Muscle Function Following Respiratory Muscle Training in Frail Older Adults
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on diaphragmatic and respiratory muscle function in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Respiratory Muscle Weakness, Age-Related Frailty, Geriatric Health
- Trial name
- IMT-1 (NCT07258615)
- Testing
- Inspiratory Muscle Training
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Francisco de Vitoria
Muscle Strength, Muscle Weakness
Reliability and Validation of New Manual Dynamometer to Measure Lower Limb Strength
INTRODUCTION: There are several ways to assess muscle strength: not only subjective ways, but also high standard equipment, such as isokinetic dynamometers. These, however, are expensive, and require extensive training.
- Trial name
- NCT05573139
- Testing
- Assessment of muscle strength by manual dynamometry
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Increased Lordosis/Scoliosis, Hyporeflexia
Biomarker for Duchenne Muscular Dystrophy
International, multicenter, observational, longitudinal study to identify biomarker/s for Duchenne Muscular Dystropy (DMD) and to explore the clinical robustness, specificity, and long-term variability of these biomarker/s.
- Conditions
- Increased Lordosis/Scoliosis, Hyporeflexia, Duchenne Muscular Dystrophy, Red-Green Color Blindness
- Trial name
- BioDuchenne (NCT02994030)
- Where
- 12 sites in Albania, Egypt and 6 more
- Volunteers
- 103 people
- Sponsor
- CENTOGENE GmbH Rostock
Weakness of the Lower Limbs
VERARE : Effectiveness of Virtual Motor Actions for Improving Walking in Patients With Post-resuscitation Muscle Weakness
After a hospitalization in Intensive Care Unit (ICU), approximately 50% of patients usually have a ICU-Weakness, i.e. nerves and muscles injury secondary to immobilization and to treatments which had to be used.
- Trial name
- VERARE (NCT04441164)
- Testing
- Observation of Virtual Actions, Relaxation, Acceptability questionnaire
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Diastasis Recti and Weakness of the Linea Alba
Impact of Exercise on Diastasis Rectus Abdominus
The aim with this research project is to evaluate the success of diastasis recti closure after a 4-week group exercise class that includes: strengthening of each abdominal muscle group, hip strengthening and stabilization, and…
- Trial name
- NCT04049487
- Testing
- Exercise
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Vocal Weakness(Post-BOTOX Injection)
Firdapse for Post-BOTOX Vocal Weakness
Botox injections into the thyroarytenoid muscle are a predictable and effective treatment for SD, but typically result in transient symptoms of voice weakness and breathiness during the first 2-3 weeks after injection.
- Trial name
- NCT05123053
- Testing
- Amifampridine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Augusta University
Muscle Weakness
CAPABLE for Frail Dually Eligible Older Adults
The Johns Hopkins School of Nursing offers this research study which aims to learn more about whether services that help with medications, muscle strengthening, pain management and changes to houses can help improve older adults'…
- Trial name
- CAPABLE500 (NCT01743495)
- Testing
- 10 home-based functional services sessions over 4 months.
- Where
- United States
- Volunteers
- 281 people
- Sponsor
- Johns Hopkins University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.