Clinical trials: Weakness
Hypothyroidism Primary
The Effect of Respiratory Muscle Training on Respiratory Parameters
The goal of this randomized controlled study is to find out whether an eight-week respiratory muscle training program can improve breathing, respiratory muscle strength and endurance, physical capacity, body composition, fatigue…
- Trial name
- NCT07865975
- Testing
- Progressive Muscle Training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Old Age; Debility
Combined Effects of NMES and LIRT on Muscle Strength, Girth, and Physical Endurance in the Geriatric Population
This study will employ a randomized controlled trial design with a pre-post design to investigate the combined effects of Neuromuscular Electrical Stimulation (NMES) and Low-Intensity Resistance Training (LIRT) on muscle…
- Trial name
- NCT07646405
- Testing
- Neuromuscular electrical stimulation, lOW intensity resistance training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Asthenia
Clinical Trial to Evaluate Short-term Efficacy of Palliative Methylphenidate in Asthenia in Advanced Cancer Patients
Fatigue is the most prevalent symptom in advanced cancer patients, interfering functional capacity, social relations, wellbeing, and quality of life.
- Trial name
- NCT01773837
- Testing
- methylphenidate
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Muscle Weakness
Safety Evaluation of Functional Electrical Stimulation (FES) Cycling in Intensive Care Unit Patients
Intensive care unit acquired muscle weakness (ICUAW), is a common disease which influence rehabilitation, extend mechanical ventilation and length of stay in intensive care unit, and affect quality of life at hospital discharge.
- Trial name
- FES Cycling (NCT03526211)
- Testing
- FES cycling
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Kidney Transplant; Complications, Postoperative Residual Curarization
Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade at the End of Kidney Transplantation Surgery
The purpose of this study is to compare two medications that reverse muscle paralysis at the end of kidney transplant surgery with the goal of reducing residual muscle weakness and insufficient respiratory function after surgery.
- Conditions
- Kidney Transplant; Complications, Postoperative Residual Curarization, Postoperative Residual Weakness
- Trial name
- NCT03923556
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Colorado, Denver
ICU Acquired Weakness
Diagnosing Intensive Care Unit (ICU) Acquired Weakness
The goal of this study is to develop a non-invasive test to diagnose intensive care unit (ICU) acquired weakness that can be administered to both responsive and non-responsive patients.
- Trial name
- NCT04166630
- Testing
- Clinical Electrical Stimulator
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Erectile Dysfunction, Premature (Early) Ejaculation
Effectiveness of Pelvic Floor Therapy for the Management of Erectile Dysfunction and Premature Ejaculation.
The objective of this clinical trial is to evaluate the effectiveness of pelvic floor therapy for the management of erectile dysfunction and premature ejaculation in patients with erectile dysfunction and premature ejaculation.
- Conditions
- Erectile Dysfunction, Premature (Early) Ejaculation, Premature Ejaculation, Pelvic Floor; Weak
- Trial name
- NCT06425211
- Testing
- Therapeutic exercises, Perineal electromyographic biofeedback, Electrical stimulation
- Where
- Colombia
- Volunteers
- 66 people
- Sponsor
- Boston Medical Group
Old Age; Debility
Motor Imagery Training in Community Dwelling Elderly
An aging society is known as having at least 7% of its population aged 65 and older, whereas 14% or more known to be an aged nation.
- Trial name
- NCT04919044
- Testing
- Motor Imagery Training
- Where
- Malaysia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Tunku Abdul Rahman
Muscle Atrophy, Cachexia
Vitamin K2 Supplements for Muscle Recovery
Ankle injury is one of the most common injuries which can have long term consequences. Ankle immobilization is often applied for up to six weeks to ensure healing of the soft tissue and fractured bones after such an injury.
- Trial name
- Recovery (NCT05161975)
- Testing
- Vitamin K2
- Where
- 2 sites in Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Anterior Cruciate Ligament Injury
Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction
The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT03209531
- Testing
- Operant Conditioning, Control, Single Pulse Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Michigan
Dementia, Weakness in the Exercise of the Family Caregiver Role of Older Adults With Dementia
Conectando Corazones Intervention in Family Caregivers of an Older Adult With Dementia
The objective of this randomized clinical trial, with pre-test and post-test measurements in an experimental group and a comparison group, was to evaluate the effect of the systematized nursing intervention "Conectando Corazones"…
- Trial name
- CONNECTING-FC (NCT07695194)
- Testing
- Conectando corazones, Conventional intervention
- Where
- Colombia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de la Sabana
Anorexia, Cachexia
Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05)
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Infliximab may improve cancer-related weight loss, lack of appetite, and fatigue.
- Conditions
- Anorexia, Cachexia, Fatigue, Lung Cancer
- Trial name
- NCT00040885
- Testing
- infliximab, docetaxel
- Where
- 188 sites in United States
- Volunteers
- 67 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Stability, Old Age; Debility
The Feasibility of a Dynamic Exercise Intervention. Psychosocial Effects and Process Evaluation of the Experimental Design.
Current balance and stability interventions have been shown to improve balance through targeting balance impairments and retraining effects.
- Conditions
- Stability, Old Age; Debility, Balance; Distorted
- Trial name
- NCT04932408
- Testing
- Evaluation of the feasibility, psychosocial effects, influence and perception of exercise selection an experimental design of exercises performed at the hip and chest region.
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Derby
Respiratory Muscle Weakness
Inspiratory Training in Children After Fontan
This study will assess physical and respiratory capacity, diaphragmatic mobility and quality of life. Healthy children and children who have undergone Fontan surgery will participate.
- Trial name
- NCT06580808
- Testing
- Fontan Training Group
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Pelvic Floor Muscle Weakness, Dysmenorrhea
Core Muscle Strength in Women with Primary Dysmenorrhoea
The aim of this study is to compare core muscle strength, core muscle activations, and pelvic tilt angles in women with and without Primary Dysmenorrhea (PD).
- Conditions
- Pelvic Floor Muscle Weakness, Dysmenorrhea, Posture
- Trial name
- NCT06854900
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Derya Azim
Cardiac Diseases, Muscular Weakness
Biomarker for Pompe Disease (BioPompe)
Development of a new MS-based biomarker for the early and sensitive diagnosis of Pompe disease from blood (plasma)
- Conditions
- Cardiac Diseases, Muscular Weakness, Hepato-splenomegaly, Lung Disease
- Trial name
- BioPompe (NCT01457443)
- Where
- 4 sites in Germany, India and 1 more
- Sponsor
- CENTOGENE GmbH Rostock
Anterior Cruciate Ligament Reconstruction, Regional Anesthesia, Saphenous Nerve Block
Comparing Subsartorial Saphenous Nerve Blocks With and Without Dexamethasone for Anterior Cruciate Ligament Reconstruction
For patients undergoing Anterior Cruciate Ligament reconstruction surgery, the postoperative period can be a painful experience without adequate pain management.
- Trial name
- NCT01586806
- Testing
- Bupivacaine Only, Bupivacaine with 1 mg of Dexamethasone, Bupivacaine with 4 mg of Dexamethasone
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Hospital for Special Surgery, New York
Cerebrovascular Stroke, Muscle Weakness
Cold Therapy and Cross-Education of Muscle Strength
The aim of this study is to investigate whether a cold application to the contralateral (affected side) extremity in addition to unilateral neuromuscular electrical stimulation (NMES) application has a facilitating effect on…
- Trial name
- NCT04886843
- Testing
- Cold pack, NMES
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Hip Fractures, Peripheral Nerve Block
Pericapsular Nerve Block and Iliopsoas Fascial Plane Block in Hip Surgery
This prospective randomized interventional study aims to compare the effects of two peripheral nerve blocks, the periencapsular nerve block (PENG) and iliopsoas block (IPB), on analgesia and motor function after hip surgery.
- Trial name
- NCT06267716
- Testing
- PENG block, IPB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Muscle Weakness
Delivra Topical Creatine Combined With Oral Creatine for Improving Muscular Power
Creatine is a nutritional supplement that is often ingested to improve exercise performance. The advent of a new product that is applied to the skin overlying muscle offers potential benefit, if the creatine can be targeted to…
- Trial name
- NCT03006861
- Testing
- 3.5 mL/d topical creatine, 21 g/d Oral creatine
- Where
- 3 sites in Canada
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
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