Clinical trials: Weakness
Burns - Multiple, Critical Illness
Reduction of Muscle Catabolism Through Brain Activation in Burn Patients
Patients with extensive burn injuries frequently develop severe skeletal muscle wasting and weakness as part of critical illness-related myopathy and neuropathy.
- Conditions
- Burns - Multiple, Critical Illness, Muscle Weakness
- Trial name
- REMBRANT (NCT07435402)
- Testing
- Burn-Bundle Extended Rehabilitation Program, Isoflurane Inhalational Sedation, Functional Proprioceptive Stimulation
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- Charles University, Czech Republic
Muscle Weakness, Syndrome; Institutionalization
Respiratory Muscle Training in Institutionalized Elderly Population
The global loss of muscle mass and strength associated with aging is a cause of functional impairment and disability, particularly in the frail elderly.
- Conditions
- Muscle Weakness, Syndrome; Institutionalization, Other Diagnoses, Comorbidities, and Complications
- Trial name
- NCT01624272
- Testing
- Threshold® Inspiratory Muscle Trainer (Respironics® Health Scan Inc. Cedar Grove, NJ, USA)., Yoga Pranayama breathing exercises
- Where
- 3 sites in Spain
- Volunteers
- 71 people
- Sponsor
- University of Valencia
Healthy Participants
Pain Inhibition With Neuromuscular Electrical Stimulation
The purpose of this study is to demonstrate the pain relieving effect of neuromuscular electrical stimulation that is applied for the purpose of increasing muscle force output.
- Trial name
- NCT05280522
- Testing
- Volitional Contractions (VOL), Neuromuscular Electrical Stimulation (NMES), Noxious Electrical Stimulation (NXES)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New England
Sensorineural Hearing Loss, Vestibular Hypofunction
Optimizing Cochlear Implant Laterality in Patients With Unilateral Vestibular Weakness
In patients with symmetric hearing loss who meet traditional cochlear implant candidacy criteria yet demonstrate pre-operative unilateral vestibular weakness, the choice of which ear to implant may impact their post-operative…
- Trial name
- NCT07452653
- Testing
- Ipsilateral cochlear implantation in patients with unilateral vestibular hypofunction, Contralateral cochlear implantation in patients with unilateral vestibular hypofunction
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Muscle Weakness
Effects Resistance Training on Motor Control and Cognition
It is well documented that both balance and resistance training have the potential to mitigate intrinsic fall risk factors in older adults.
- Trial name
- KFPS_2 (NCT03017365)
- Testing
- Stable Resistance Training, Unstable Resistance Training, Adductor/Abductor Resistance Training
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Kassel
Weakness
Early Cycloergometric Physiotherapy in Critically Ill Patients With Invasive Mechanical Ventilation
Study designed to evaluate the functional and motor effects in critically ill subjects at ICU and hospital discharge with the incorporation of a mobilization program of cycloergometric physiotherapy sessions compared with…
- Trial name
- NCT02478411
- Testing
- Cycle ergometer physiotherapy, Conventional physiotherapy
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Hospital Son Llatzer
Burns, Muscle Weakness
Reallocating Rehabilitation Time to Wii Fit or Pilates After Lower-Limb Burn Injury
This randomized controlled trial will evaluate whether reallocating part of a fixed-duration supervised rehabilitation session to Wii Fit or Pilates will improve functional outcomes in adults with healed lower-extremity burns.
- Conditions
- Burns, Muscle Weakness, Exercises, Functional Performance
- Trial name
- NCT06081504
- Testing
- Wii fit exercises program, Pilates exercises program, Standard physical therapy program
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Pelvic Floor Muscle Weakness, Postpartum
The Pelvic Floor Muscle Function in Chinese Primipara, a One-year Cohort Study
It is a prospective cohort study.The primiparas in six geographic regions of China are recruited to observe the natural recovery of pelvic floor muscle.
- Conditions
- Pelvic Floor Muscle Weakness, Postpartum, Primiparity
- Trial name
- NCT03506204
- Where
- China
- Volunteers
- 3,120 people
- Sponsor
- Peking Union Medical College Hospital
Weakness, Balance
A Randomised Controlled Trial of Family Mediated Exercises (FAME) Following Stroke
The aim of the study is to evaluate the functional recovery in two groups of primary stroke patients presenting with moderate/severe disability over a six month period through the implementation of a randomised controlled trial.
- Trial name
- FAME (NCT00666744)
- Testing
- Family Mediated Exercise Therapy
- Where
- 2 sites in Ireland
- Volunteers
- 40 people
- Sponsor
- University of Dublin, Trinity College
Upper Extremity Problem, Muscle Weakness
Effects of Biofeedback-Guided Training on Muscle Strength and Postural Alignment in Upper Cross Syndrome.
This randomized controlled trial investigates the effects of biofeedback-guided training versus conventional therapy on muscle strength and postural alignment in patients with Upper Cross Syndrome.
- Conditions
- Upper Extremity Problem, Muscle Weakness, Postural Kyphosis
- Trial name
- NCT07026084
- Testing
- Bio feedback training, conventional exercise program
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Stroke
Telerehabilitation for Post-Stroke Hand Function
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a home-based, technology-enabled hand telerehabilitation program for adults with chronic stroke.
- Trial name
- NCT07792655
- Testing
- Technology-Supported Hand Training, Pamphlet-Supported Hand Activity
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Muscle Weakness
Lumbar Paraspinal Muscle Fatty Infilteration
Introducing a unique clinical case of limb-girdle muscular dystrophy associated with LBP that was initially misdiagnosed as non-specific LBP
- Trial name
- NCT06884371
- Testing
- physical therapy
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Noha Khaled Shoukry
Speech and Language Disorder, Cerebral Palsy
Effect of mCIMT Casting on Speech-language Outcomes in Children With Hemiparesis
Modified constraint-induced movement therapy (mCIMT) has been successfully used with children who have hemiplegia (weakness or paralysis on one side of the body.) mCIMT uses a removable cast during treatment and home exercise…
- Conditions
- Speech and Language Disorder, Cerebral Palsy, Hemiplegia, Hemiparesis
- Trial name
- NCT04259814
- Testing
- Speech-language therapy (SLT), Modified constraint-induced movement therapy (mCIMT)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Shirley Ryan AbilityLab
Muscle Weakness, Muscle Loss
A Study on the Effects on Glucose Regulation, Inflammation and Serum Lipids After Fish Protein Supplementation in Elderly (GRIPE)
The elderly population have and increased risk of loss of both muscle mass and function and is therefore recommended a higher protein intake than the healthy adult population.
- Conditions
- Muscle Weakness, Muscle Loss, Blood Sugar; High, Inflammation
- Trial name
- GRIPE (NCT03529344)
- Testing
- Blue whiting protein hydrolysate
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Hemochromatoses, Genetic
Transferrin Saturation and Asthenia in Hemochromatosis
Observational study.
- Trial name
- HEMOSAT (NCT03356548)
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Rennes University Hospital
Amyotrophia, Weakness, Muscle
Diagnosis of Muscular Weakness Syndrome After a Stay in Intensive Care : Measurement by Ultrasound
The objective is to diagnose earlier and more precisely the occurrence of a weakness neuromuscular syndrome at the end of intensive care, or within 28 days if the stay is longer than 28 days.
- Trial name
- FIBER (NCT03735693)
- Testing
- Ulstrasound
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Association Pro-arte
Chronic Disease, Old Age; Debility
CONNECARE-Assuta-Case Study 1
The European Union's Horizon 2020 project issued a Call for Action [1] in December 2013 to design, develop, disseminate and evaluate new IT technologies for use in integrative treatment processes, with emphasis on complex adult…
- Trial name
- NCT03327233
- Testing
- Connecare self managment system
- Volunteers
- 220 people
- Sponsor
- Assuta Medical Center
Muscle Weakness, Critical Illness
Translation and Validation of the Intensive Care Unit Mobility Scale (IMS)
Intensive care unit acquired weakness (ICUAW) is a common issue in critically ill patients. Early mobilization can reduce the occurrence of ICUAW. This requires a standardized procedure based on validated scales.
- Conditions
- Muscle Weakness, Critical Illness, Mechanical Ventilation Complication, Early Mobilization
- Trial name
- TAVIMS (NCT05591950)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Critical Illness, Dysphagia
Detection of Neuromuscular Complications in Critically Ill Patients
Dysphagia and the intensive care unit-acquired weakness (ICU-AW) are common and outcome-relevant neuromuscular complications in critically ill patients, especially after prolonged mechanical ventilation, sepsis and multi-organ…
- Conditions
- Critical Illness, Dysphagia, Intensive Care Unit Acquired Weakness, Neuromuscular Diseases
- Trial name
- NMCiCIP (NCT04541602)
- Where
- Germany
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Rostock
Pelvic Floor Muscle Weakness, Stroke
Multimodal Pelvic Floor Rehabilitation in Chronic Stroke Survivors: Long-Term Efficacy, Optimal Protocols, and Adjunctive Therapies for Comprehensive Pelvic Floor Dysfunction.
Evaluate long-term efficacy of multimodal PFMT in chronic stroke survivors with PFD.
- Trial name
- RCT (NCT07420569)
- Testing
- Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks. • Group A (Standard PFMT): 3 supervised/week (weeks 1-8), 1/week (9-16) + home. • Group B (Intensified PFMT): 5/week, Core PFMT: 8-12 contractions (6-10s hold), 3 sets/day, progressed over 16 weeks.
- Where
- Uganda
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iqra National University
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