Clinical trials: Weakness
Pain, Soreness
Benefit of CoQ-10 in Patients on Statins
This study will investigate whether a supplement called co-enzyme Q10 can help ease or eliminate some of the side effects that result from taking statin medications.
- Conditions
- Pain, Soreness, Weakness, Fatigue
- Trial name
- CoQ-10 (NCT00997269)
- Testing
- Co-enzyme Q-10
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Stony Brook University
Diaphragm, Diaphragm Disease
Diaphragmatic Ultrasound and Weaning After Lung Transplant.
The prevalence and adverse effect of diaphragm dysfunction (DD) after bilateral-lung transplant (LT) are still unclear, despite a well-known negative impact on weaning and outcome in other cohorts of critically ill and surgical…
- Conditions
- Diaphragm, Diaphragm Disease, Diaphragm Issues, Weakness, Muscle
- Trial name
- NCT05670327
- Testing
- Diaphragmatic ultrasound assessment
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- University of Padova
Old Age; Debility
Fall Prevention Pathways
Falls are a leading cause of injury and loss of independence in older adults, with evidence supporting exercise-based interventions and remote monitoring as effective strategies for reducing fall risk.
- Trial name
- NCT07824141
- Testing
- The Fall Prevention Pathway (FPP)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emory University
Pompe Disease
Frequency of Pompe's Disease and Neuromuscular Etiologies in Patients With Restrictive Respiratory Failure Associated With Signs of Muscle Weakness
A breach of respiratory function may be one of the elements more or less early or predominant clinical picture of neuromuscular diseases.
- Trial name
- POPS3 (NCT02746718)
- Testing
- Blood sample
- Where
- 21 sites in France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
ICU-acquired Weakness
Safety and Efficacy of an Early Rehabilitation Program in Surgical Intensive Care Unit
The purpose of this study is to determine whether an early rehabilitation program in surgical intensive care unit is safe and effective in preventing critical care illness and intensive care unit acquired weakness.
- Trial name
- ERP (NCT03055949)
- Testing
- Early rehabilitation program
- Volunteers
- 131 people
- Sponsor
- Asan Medical Center
Arm Weakness as a Consequence of Stroke
Effects of Post-Stroke Upper Extremity Assistance
The purpose of this study is to quantify the improvement of post- stroke individuals' ability to move their arms during and after robot assisted therapy.
- Trial name
- NCT05036642
- Testing
- Compliant Passive Arm Support
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
ICU Acquired Weakness, Rehabilitation
Effects of Respiratory Rehabilitation on ICU Patients
Effects of respiratory rehabilitation on patients after extubation
- Trial name
- NCT04368286
- Testing
- pulmonary rehabilitation
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Heart Failure, Old Age; Debility
The Effects of an Exercise Programme for Older Patients With Heart Failure
Patients with heart failure have decreased exercise tolerance, balance problems, and fall risks. The purpose of this research was to investigate the effect of an exercise program based on the Empowerment Model for participants…
- Trial name
- NCT04022369
- Testing
- Exercise Group
- Volunteers
- 21 people
- Sponsor
- Emine Karaman
Myasthenia Gravis
Prevalence and Impact of Fatigue in Myasthenic Patients Followed At Clermont-Ferrand University Hospital - "My" Asthenia
After identifying myasthenic patients meeting the inclusion criteria, telephone contact with patients to suggest that they participate in the study by responding to various questionnaires composed of validated scales used in…
- Trial name
- NCT06877403
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anxiety Disorders, Depressive Disorder
Transdiagnostic Treatment Personalization
The primary purpose of this study is to explore whether the efficiency of treatment for anxiety and depressive disorders can be increased using two discrete strategies: personalized skill ordering and 2) treatment discontinuation…
- Conditions
- Anxiety Disorders, Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04584879
- Testing
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Cerebral Palsy, Weakness
Use of Surface Electromyography Biofeedback to Improve Reaching in Children With Cerebral Palsy
A newly-developed device for biofeedback of surface EMG will be used to either increase or decrease activity in the muscles of children with poor reaching due to cerebral palsy.
- Conditions
- Cerebral Palsy, Weakness, Hypertonia
- Trial name
- NCT00473161
- Testing
- surface EMG biofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Muscle Weakness
Effect of Mode of Femoral Nerve Analgesia on Quadriceps Muscle Strength
Quadriceps muscle strength is an important determinant of quality of recovery in elderly patients after total knee arthroplasty.
- Trial name
- NCT02007850
- Testing
- ropivacaine
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Seoul National University Hospital
Cerebral Palsy
Study Assessing High-Frequency Chest Wall Oscillation (HFCWO) in Preventing Pulmonary Exacerbations
To asssess efficacy of airway clearance provided by Vest therapy (HFCWO) in the reduction of respiratory exacerbations requiring hospitalization or antibiotic utilization in patients with muscle weakness and restrictive lung…
- Trial name
- NCT00739310
- Testing
- Vest Treatment (high frequency chest wall oscillation)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Hill-Rom
Carnitine Deficiency
Identification of Carnitine-Responsive Cardiomyopathy
There are some adults with skeletal muscle weakness (called "myopathy") and heart muscle weakness (called "cardiomyopathy") who have low blood levels of a compound called carnitine as a cause of their problems.
- Trial name
- C001 (NCT01904396)
- Testing
- Carnitine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Stroke, Arm Weakness as a Consequence of Stroke
Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization
The goal of this research study is to optimize the parameter of Low-Intensity Focused Ultrasound Stimulation (LIFUS) that is most effective in changing cortical excitability and motor learning skills in patients who suffered a…
- Conditions
- Stroke, Arm Weakness as a Consequence of Stroke, Upper Extremity Hemiparesis, Upper Extremity Impairments
- Trial name
- LIFUS-OPTIMIZE (NCT07220005)
- Testing
- Low intensity focused ultrasound stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Oxidative Stress, Inflammation
Once-Daily Oral Dose of BeneFlax to Healthy Older Adults
The investigators are investigating whether the flax lignan, secoisolariciresinol diglucoside, decreases oxidative stress and inflammation.
- Conditions
- Oxidative Stress, Inflammation, Aging, Pain
- Trial name
- MOD (NCT01846117)
- Testing
- secoisolariciresinol diglucoside, vitamin D
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
ICU Acquired Weakness, Muscle Atrophy
Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO )
Intensive Care Unit Acquired Weakness (ICUAW) describes muscle weakness that occurs in around 40% of patients during an intensive care stay.
- Conditions
- ICU Acquired Weakness, Muscle Atrophy, Energy Malnutrition Protein, Quality of Life
- Trial name
- NCT05919940
- Testing
- Dietary Supplement: additional substitution of protein, Neuromuscular electrical stimulation, Early Mobilization
- Where
- 4 sites in Austria, Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Intensive Care (ICU) Myopathy, Intensive Care Unit Acquired Weakness
Effect of Neurophysiological Facilitation Techniques in Intensive Care Patients
The aim of this study was to investigate the effect of neurophysiological facilitation techniques on respiratory and functional levels in intensive care patients.
- Trial name
- NCT05282576
- Testing
- NPF Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Saglik Bilimleri Universitesi
Pelvic Floor Muscle Weakness
A Randomized Controlled Trial Comparing the Effect of Pelvic Floor Muscle Training
Aim: To determine the effects of pelvic floor muscle training (PFMT) in women with a single delivery route. Pregnancy and delivery route alter the pelvic floor muscle strength and are considered risk factors for urinary…
- Trial name
- PFMT (NCT01794910)
- Testing
- Pelvic floor muscle therapy
- Where
- Brazil
- Volunteers
- 297 people
- Sponsor
- University of Sao Paulo
Sarcopenia, Muscle Weakness
HORMA: Hormonal Regulators of Muscle and Metabolism in Aging
The purpose of this study is to determine the relationship of deficiencies in testosterone and growth hormone to loss of muscle mass (sarcopenia) and functional impairment during aging and whether there is an interaction of these…
- Conditions
- Sarcopenia, Muscle Weakness, Frailty
- Trial name
- NCT00183040
- Testing
- Topical testosterone, Recombinant human growth hormone
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- National Institute on Aging (NIA)
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