Clinical trials: Weakness
Pain, Shoulder, Postoperative Pain
The Effects of Qigong Exercise Training After Thoracotomy
Postoperative pulmonary complications after thoracotomy cause morbidity and mortality. Although the causes of postoperative pulmonary complication are multifactorial, respiratory muscle dysfunction is a contributing factor to the…
- Conditions
- Pain, Shoulder, Postoperative Pain, Joint Adhesion, Muscle Weakness
- Trial name
- NCT05470192
- Testing
- Qigong exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Akdeniz University
Glioma
Dexamfetamine Sulphate in Patients With Glioma Suffering From Severe Asthenia
The main purpose of this study is to estimate the efficiency at 3 months of dexamfetamine sulphate on the MFI 20 scale in severe fatigue of patients with stabilized gliomas.
- Trial name
- DXA (NCT02363075)
- Testing
- Dexamfetamine sulphate
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post-extubation Failure, Persistent Weaning Failure
Effects of Mechanical Insufflation-Exsufflation in Preventing Respiratory Failure After Extubation
Weaning protocols that include the use of noninvasive ventilation (NIV), decreases the incidence of re-intubation and ICU length of stay. However, the role of NIV in post-extubation failure is still not clear.
- Conditions
- Post-extubation Failure, Persistent Weaning Failure, Secretion Encumbrance, Weak Cough
- Trial name
- MIEICU (NCT01424202)
- Testing
- Mechanical Insufflation Exsufflation
- Where
- Portugal
- Volunteers
- 92 people
- Sponsor
- Hospital Sao Joao
Healthy Aging, Nutritional Status
OPTIPROT, Targeted Precision Nutrition for Protein Needs in Ageing
This multicenter, cross-sectional observational study aims to use precision nutrition tools to identify metabolic clusters in adults aged 50-75 years, enabling tailored nutritional and protein recommendations based on specific…
- Conditions
- Healthy Aging, Nutritional Status, Dietary Protein, Muscle Weakness
- Trial name
- OPTIPROT (NCT07436936)
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Stroke Rehabilitation
Muscle Strength Loss In Stroke Individuals - Control Study
ABSTRACT The muscle strength (MS) is necessary to overcome the resistance encountered during the activity. The present study aims to determine MS loss in stroke individuals (SI).
- Trial name
- NCT04395209
- Testing
- assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Muscle Weakness, Problems Moving Their Arms and Legs
Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults
People with cerebral palsy (CP), muscular dystrophy (MD), spina bifida, or spinal cord injury often have muscle weakness, and problems moving their arms and legs.
- Trial name
- NCT06998134
- Testing
- Extension assist knee ankle foot orthosis (EA-KAFO)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cerebral Palsy (CP), Diaplegia
Effect of Treatment on Cerebral Palsy Patient With Crouch Gait Associated With Anterior Pelvic Tilt and Soleus Muscle Weakness"Marouf Syndrome", and Muscle Assesment by Using EMG
Children with cerebral palsy (CP) often develop gait abnormalities, with crouch gait being a common and challenging issue that affects their posture and daily function.
- Conditions
- Cerebral Palsy (CP), Diaplegia, Muscle Weakness | Patient, Anterior Pelvic Tilt
- Trial name
- NCT07147933
- Testing
- phusical therapy program, physical therapy program
- Where
- Jordan
- Volunteers
- 40 people
- Sponsor
- Philadelphia University, Jordan
Dynamic Knee Valgus
The Effects of Open Chain Versus Closed Chain Strengthening on Dynamic Valgus During a Step Down Test
The goal of this clinical trial is to compare the effects of different exercises programs in individuals with abnormal knee motion.
- Trial name
- NCT06348836
- Testing
- Exercise
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Alvernia University
Amyotrophic Lateral Sclerosis, Respiratory Muscle Weakness
ALS and Airway Clearance (ALSAC) Therapy
Patients will receive one of three respiratory therapy interventions for airway clearance assistance: 1) High frequency chest wall oscillation (HFCWO) and mechanical insufflation/exsufflation (MIE), 2) HFCWO or 3) MIE.
- Trial name
- ALSAC (NCT04947436)
- Testing
- High Frequency Chest Wall Oscillation, Mechanical insufflation/exsufflation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Sarcopenia, ICU Acquired Weakness
ICU Associated Weakness and Bedside Ultrasound Assessment
ICU-associated weakness is a common experience for people following a critical illness. It is associated with important patient and system-relevant outcomes.
- Trial name
- NCT04095533
- Testing
- Tibialis anterior muscle cross-sectional area assessment by ultrasound, Muscle strength assessment
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Calgary
Myopathy, Muscular Weakness
Efficacy and Tolerance of Early Launching of Nocturnal Non Invasive
This is a multicenter randomized controlled open labeled study testing efficacy and tolerance of early launching of night non invasive ventilation in patients with myotonic dystrophy type 1(DM1).
- Conditions
- Myopathy, Muscular Weakness, Respiratory Insufficiency
- Trial name
- DYVINE (NCT01225614)
- Testing
- Bilevel pressure ventilator
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anterior Cruciate Ligament Injuries, Knee Injuries
Effects of Early Rehabilitation Using Blood Flow Restriction and/or Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial
Many patients experience quadriceps inhibition after anterior cruciate ligament (ACL) reconstruction, delaying strength recovery, hindering return to sport, and potentially increasing the risk of re-injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Muscle Weakness
- Trial name
- NCT07145606
- Testing
- Standard Rehabilitation, Blood Flow Restriction (BFR) Training, sEMG Biofeedback
- Where
- 4 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- Haute Ecole ARC Sante
ICU Acquired Weakness
Impact of Early Mobilization on Mechanical Ventilation Duration in Intubated Critically Ill Patients
The purpose of the present study is to compare usual care in terms of mobilization performed to intubated ICU patients to a standardized program designed to deliver early mobilization at least 5 days a week.
- Trial name
- EarlyMob (NCT02520193)
- Testing
- Protocolized early mobilization in ICU
- Where
- 23 sites in Belgium, France and 1 more
- Volunteers
- 772 people
- Sponsor
- University Hospital, Angers
Muscle Weakness, Postural Balance
Effects of a Multidisciplinary Intervention on Muscle Strength, Posture, and Balance in Older Adults After an Earthquake
This randomized controlled trial evaluated the effects of a 12-week multidisciplinary intervention on muscle strength, postural alignment, and balance in older adults living in temporary container settlements following the…
- Conditions
- Muscle Weakness, Postural Balance, Physical Functional Performance, Frail Elderly
- Trial name
- NCT07910981
- Testing
- Multimodal Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Stroke, Cerebrovascular Accident
Rehabilitation Robotics, Cognitive Skills Training and Function
This study evaluates the effects of robot-assisted therapy for adults more than 6 months after stroke on upper limb functioning.
- Trial name
- NCT03599544
- Testing
- Robot-Assisted Therapy (RT), Robot + Active Learning Program(RT-ALPS)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Spaulding Rehabilitation Hospital
Accidental Falls, Muscle Weakness
The Effects of a Walking Program on Balance, Falls and Well Being in Individuals Residing in Long-term Care
The purpose of this study is to assess the effectiveness of a regular walking program (which inevitably involves human interaction) compared to a usual care condition and to a human interaction condition (without the extra…
- Conditions
- Accidental Falls, Muscle Weakness, Gait, Unsteady, Depression
- Trial name
- NCT01277809
- Testing
- Interpersonal Interaction, Walking Program
- Where
- Canada
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Esophageal Cancer, Nutrition Aspect of Cancer
Assessing Timing of Enteral Feeding Support in Esophageal Cancer Patients on Muscle functTion and Survival
The surgical stress of an esophagectomy causes a detrimental impact on the physiological response of the body. In this perspective, one could question whether the current feeding regimens of starting early nutritional support at…
- Conditions
- Esophageal Cancer, Nutrition Aspect of Cancer, Postoperative Complications, Muscle Weakness
- Trial name
- EFECTS (NCT03676478)
- Testing
- delayed start enteral support @ POD5
- Where
- Belgium
- Volunteers
- 239 people
- Sponsor
- University Hospital, Gasthuisberg
Whiplash Injury of Cervical Spine, Muscle Weakness
Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders
The aim of this prospective observational study is to investigate whether the presence or absence of directional preference impacts movement coordination impairments as measured in patients with Whiplash Associated Disorders…
- Trial name
- NCT06143228
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- D'Youville College
Sarcopenia, Gait Disorders in Old Age
An OBServational Clinical Trial (SARA-OBS) in Sarcopenia and Sarcopenic Obesity in Patients Aged 65 Years and Over
The SARA-OBS is a single arm phase 2 clinical trial, with no investigational product and no therapeutic intervention that will be conducted in three European countries, (Belgium, France and Italy), and in the US.
- Conditions
- Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
- Trial name
- SARA-OBS (NCT03021798)
- Testing
- No Drug and no aspecific intervention
- Where
- 7 sites in United States, Belgium and 2 more
- Volunteers
- 218 people
- Sponsor
- Biophytis
Fecal Incontinence
Evaluation of Outcomes of Restoring Pelvic Floor Support With TOPAS in Women With Moderate Fecal Incontinence Symptoms
The study purpose is to gain experience with the TOPAS system, a minimally- invasively delivered self-fixating mesh for the treatment of pelvic floor weakness in women with symptoms of moderate fecal incontinence
- Trial name
- TOPAS (NCT00565136)
- Testing
- TOPAS
- Where
- 5 sites in United States
- Volunteers
- 29 people
- Sponsor
- ASTORA Women's Health
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