Clinical trials: Weaning Failure
Respiration Disorder, Respiratory Failure
Impact of the Inspiratory Cortical Control on the Outcome of the Ventilatory Weaning Test in Patients Intubated in Resuscitation
In case of respiratory distress, patients are intubated to be connected to an artificial respirator to ensure gas exchanges. Before any ventilatory weaning, a breathing test in spontaneous ventilation under artificial nose is…
- Conditions
- Respiration Disorder, Respiratory Failure, Weaning Failure, Respiratory Compensation
- Trial name
- NCT03372252
- Testing
- Electroencephalography
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Poitiers University Hospital
Acute Respiratory Failure
Third International Study on Mechanical Ventilation
The objective of this study is to obtain a better understanding of the spectrum of use of mechanical ventilation in intensive care units: 1.
- Trial name
- ISMV (NCT01093482)
- Where
- 477 sites in United States, Argentina and 36 more
- Volunteers
- 8,151 people
- Sponsor
- Hospital Universitario Getafe
Heart Failure
CentriMag Ventricular Assist System in Treating Failure-to-Wean From Cardiopulmonary Bypass
The purpose of the study is to evaluate the safety and effectiveness of the CentriMag ventricular assist system to help patients who have experienced heart failure during surgery and cannot be removed from cardiac bypass.
- Trial name
- NCT00819793
- Testing
- CentriMag Ventricular Assist System
- Where
- 14 sites in United States
- Volunteers
- 32 people
- Sponsor
- Abbott Medical Devices
Neuromodulation, Phrenic Nerve Stimulation
Randomized Study of the pdSTIM™ System in Failure to Wean Mechanically Ventilated Patients
This prospective, multi-center, randomized, controlled clinical trial is being conducted to evaluate the safety and efficacy of the pdSTIM System to facilitate weaning from mechanical ventilation through phrenic nerve…
- Conditions
- Neuromodulation, Phrenic Nerve Stimulation, Ventilator Induced Diaphragm Dysfunction, Mechanical Ventilation Weaning
- Trial name
- ReInvigorate (NCT05998018)
- Testing
- pdSTIM System Therapy, Conventional Medical Management
- Where
- 16 sites in United States
- Volunteers
- 32 people
- Sponsor
- Stimdia Medical Inc.
Weaning Failure
Rest After Spontaneous Breathing Trial for Prevention of Post-extubation Failure
To evaluate if a rest period before extubation after a successful SBT trial could reduce the extubation failure rate.
- Trial name
- NCT01915563
- Testing
- REST
- Where
- Spain
- Volunteers
- 470 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Weaning Failure, Complication of Respirator [Ventilator]
Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation
Prolongation of mechanical ventilation poses serious personal and financial threats to healthcare consumers. The investigators objectives are create and implement an multidisciplinary evidenced-based ventilator-weaning protocol…
- Trial name
- NCT01482429
- Testing
- Multidisciplinary weaning-ventilator protocol
- Where
- Brazil
- Volunteers
- 235 people
- Sponsor
- Federal University of Uberlandia
Prematurity, Apnea
Caffeine to Reduce Mechanical Ventilation in Preterm Infants
Most premature infants require mechanical ventilation for prolonged periods of time and a significant proportion of them develop Bronchopulmonary Dysplasia (BPD).
- Conditions
- Prematurity, Apnea, Respiratory Failure
- Trial name
- NCT01751724
- Testing
- Caffeine citrate, Normal saline
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Miami
Acute Respiratory Failure
Pilot Study on Pairing Sedation Strategies and Weaning
A three-arm, randomized, pilot study, to assess the feasibility for the analgesia-first sedation (AFS) study arm/intervention (Fentanyl push first).
- Trial name
- NCT02219659
- Testing
- Sedation Protocol with Daily Interruption, Sedation Protocol Without Daily Interruption, Fentanyl Push First
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- MemorialCare Health System
Respiratory Failure
Extubation Readiness and Neuroventilatory Efficiency After Acute Respiratory Failure
The aim of this study was to compare the indices of rapid shallow breathing, neuromechanical efficiency (NME), and neuroventilatory efficiency (NVE) between patients being successfully extubated and those who failed weaning.
- Trial name
- NCT01065428
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Southeast University, China
Respiratory Failure
Comparison Between Two Methods of Spontaneous Breathing Trial (SBT)
To compare a new mode of mechanical ventilation, Automatic Tube Compensation (ATC) with a traditional one, Continuous Positive Airway Pressure(CPAP), on its effectiveness for detecting patients no longer needing mechanical…
- Trial name
- NCT00400881
- Testing
- automatic tube compensation
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Weaning Failure, Mechanical Ventilation Complication
Comparison of Two Extubation Techniques in Critically Ill Adult Patients
Orotracheal extubation consists in the removal of the endotracheal tube (ETT) when it is no longer required. This procedure may carry a considerable risk of complications and extubation failure.
- Trial name
- ExtubAR (NCT03918811)
- Testing
- Positive Pressure Extubation Technique, Traditional Extubation Technique
- Where
- Argentina
- Volunteers
- 725 people
- Sponsor
- Hospital Donación Francisco Santojanni