Clinical trials: Weaning-induced Pulmonary Edema
Weaning-induced Pulmonary Edema, Mechanical Ventilation Weaning
Detecting Early Weaning-induced Pulmonary Oedema Using Lung Impedance Negative Trend During SBT
Critically ill patients who require a breathing machine are routinely assessed with a spontaneous breathing trial (SBT) to determine if they can safely breathe on their own.
- Conditions
- Weaning-induced Pulmonary Edema, Mechanical Ventilation Weaning, Spontaneous Breathing Trial
- Trial name
- DEWPOINT (NCT07886671)
- Where
- Canada
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Weaning Failure, Weaning-induced Pulmonary Edema
Incidence and Risk Factors of Weaning-induced Cardiac Dysfunction: Results From a Multicenter, Observational Study
During weaning from mechanical ventilation, the shift from positive to negative pressure ventilation may be responsible for a cardiac dysfunction that can lead to the development of pulmonary oedema (weaning-induced pulmonary…
- Conditions
- Weaning Failure, Weaning-induced Pulmonary Edema, Spontaneous Breathing Trial
- Trial name
- WIPO (NCT05318261)
- Testing
- Spontaneous breathing trial
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Bicetre Hospital
Weaning-induced Pulmonary Edema
Hemodynamic Impact of the Spontaneous Ventilation Test in Patients at Risk of Weaning Pulmonary Oedema
Weaning-induced pulmonary edema (WIPE) from the ventilator is a frequent cause of extubation failure or delay, which prolongs the duration of invasive mechanical ventilation and the associated morbidity and mortality.
- Trial name
- WAPITI 2 (NCT07666880)
- Testing
- T-piece SBT, PS-ZEEP SBT
- Where
- 4 sites in France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Limoges
Detecting the Number of B-lines in Lung Ultrasound and Its Accuracy in Diagnosis of Weaning Induced Pulmonary Oedema
The Role of Lung Ultrasound in The Diagnosis of Weaning -Induced Pulmonary Edema
The aim of the work is to 1. Assess the incidence of weaning induced pulmonary adema(WIPO). 2. Assess the risk factors of WIPO. 3. Evaluate the role of lung ultrasound in detecting WIPO during spontenous breathing trial(SBT). 4.
- Trial name
- NCT04463303
- Testing
- lung ultrasound
- Volunteers
- 50 people
- Sponsor
- Assiut University
Weaning Failure, Pulmonary Edema - Acute
Quantification of Systemic Congestion by Ultrasound As a Predictor of Weaning Failure From Mechanical Ventilation
Mechanical ventilation is an essential, life-saving therapy in the ICU, allowing critically ill patients to rest and recover. Transitioning patients back to spontaneous breathing-known as weaning-is clinically challenging.
- Conditions
- Weaning Failure, Pulmonary Edema - Acute, Mechanical Ventilation, POCUS
- Trial name
- SCOUT (NCT07343882)
- Testing
- point of care ultrasound
- Volunteers
- 350 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Mechanical Ventilation Complication, Pulmonary Edema
Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)
The purpose of this study is to determine if the left and right ventricular systolic function is involved in the development of weaning failure related to weaning-induced pulmonary edema.
- Trial name
- SystoWean (NCT05226247)
- Testing
- Spontaneous breathing trial
- Where
- 3 sites in France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Weaning Invasive Mechanical Ventilation, Weaning-induced Pulmonary Edema
Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials
The goal of this clinical trial is to evaluate the evolution of a cardiac ultrasound index (E/E') during 3 spontaneous breathing trials in Intensive Care Unit (ICU) adults (over 18 years) patients at risk for weaning failure.
- Conditions
- Weaning Invasive Mechanical Ventilation, Weaning-induced Pulmonary Edema, Weaning Failure of Mechanical Ventilation, Spontaneous Breathing Test
- Trial name
- ATARI (NCT06923267)
- Testing
- No Pressure Support No Positive End Expiratory Pressure Spontaneous Breathing Trial, Pressure Support Spontaneous Breathing trial, Humidified High Flow Spontaneous Breathing Trial
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Régional d'Orléans