Clinical trials: Weather
Cardiovascular System, Health
Acute Effects of Meteorological Factors and Air Pollution on Cardiovascular Health
The goal of this observational study is to analyze the acute effects of meteorological factors and air pollution on cardiovascular system. The main question it aims to answer is: 1.
- Trial name
- NCT06663267
- Testing
- NOT
- Where
- China
- Volunteers
- 350,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Hangzhou Normal University
Hot Weather; Adverse Effect, Healthy
Characterization of Myocardial Blood Flow During Heat Exposure
The purpose of this study is to determine the increase in myocardial blood flow during heat exposure and how this response is affected by age and coronary artery disease.
- Conditions
- Hot Weather; Adverse Effect, Healthy, Coronary Artery Disease, Aging
- Trial name
- PET-Heat (NCT04549974)
- Testing
- Heat exposure
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Heat Stress, Temperature Change, Body
Identifying the Limits of Survivability in Heat-exposed Older Females
Climate change increases extreme heat events, elevating global heat-illness risk. Females have reduced heat loss capacity (~5%) compared to males, driven by differences in skin blood flow and sweating responses.
- Conditions
- Heat Stress, Temperature Change, Body, Aging, Thermoregulation
- Trial name
- NCT07032493
- Testing
- Humidity-Ramp Protocol, Above-inflection fixed-condition exposure (5%), Below-inflection fixed-condition exposure (5%)
- Where
- 2 sites in Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Hot Weather; Adverse Effect, Immobilization, Tonic
Heat Therapy to Prevent Deconditioning During Immobilization
Animal models suggest that heat stress increases protein content and facilitates the recovery of atrophied muscle after an immobilization period, or following a chemically induced muscle injury in rats.
- Trial name
- NCT05021523
- Testing
- Hot ambient conditions exposures, Immobilization
- Where
- Qatar
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aspetar
Cold Exposure
Energy Dense Fueling for Cold-Weather Operations
High daily energy expenditures without compensatory increases in energy intakes results in severe energy deficits during cold-weather military operations.
- Trial name
- NCT07489690
- Testing
- High Fat, High Carbohydrate
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Hyperthermia, Weather; Heat
Mitigating Heat-induced Physiological Strain and Discomfort in Older Adults Via Lower Limb Immersion and Neck Cooling
The incidence and severity of hot weather and extreme heat events (heat waves) is increasing. As such, there is an urgent need to develop heat-alleviation strategies that can provide targeted protection for older adults who are…
- Conditions
- Hyperthermia, Weather; Heat, Heat Stress, Heat Syncope
- Trial name
- NCT05601713
- Testing
- No cooling (control), Lower limb immersion, Lower limb immersion + neck cooling
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Hyperthermia, Heat; Weather
Protective Cooling Measures to Safeguard Elderly People From Dangerous Summer Heat
With the increasing incidence and severity of extreme heat events accompanying climate change, there is an urgent need for sustainable cooling strategies to protect heat-vulnerable older adults, who are at increased risk of…
- Conditions
- Hyperthermia, Heat; Weather, Aging, Type2 Diabetes
- Trial name
- NCT05274009
- Testing
- No cooling (control), Recommended cooling, Hybrid cooling
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Heat Stress, Temperature Change, Body
The Impact of Wearing the Hijab on Whole-body Heat Loss During Exercise-heat Stress
The hijab (headscarf and cloak) is a Muslim dress, which covers the head, neck and chest, and conceals the female hair, leaving the face uncovered.
- Trial name
- NCT07174180
- Testing
- Exercise-heat stress with no hijab, Exercise-heat stress with a hijab
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Heat Acclimation and Thermotolerance, Heat Effect
Exercise in Extreme Hot Weather Conditions
Background: Core body temperature increases in hot climates due to exercise workload, disrupting heat gain and loss of balance. The human thermoregulatory system regulates core body temperature through factors such as metabolic…
- Trial name
- EXHOTCON (NCT07307391)
- Testing
- hot wet high (HWH), hot dry high (HDH), Experimental: hot dry low (HWL)
- Where
- Spain
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Chronic Disease, Mental Health
Alaska Alliance for Community Engagement Phase II: Partnership for Action Toward Health
The AK ACE-PATH Phase II study aims to pilot and implement a novel intervention, Tools for Arctic Health Promotion (TAHP), to address Alaska Native (AN) community priorities related to local health and community-level resilience.
- Conditions
- Chronic Disease, Mental Health, Caridovascular Disease, Stress
- Trial name
- AK ACE-PATH (NCT07801989)
- Testing
- Tools for Arctic Health Promotion
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Alaska Fairbanks
Hot Weather; Adverse Effect, Kidney Dysfunction
Renal Considerations in the Heat Stress Recommendations (Aim2)
An epidemic of chronic kidney disease is occurring in laborers who undertake physical work outdoors in hot conditions. The reason for this is largely unknown, but may be related to kidney dysfunction caused by increases in body…
- Conditions
- Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia
- Trial name
- NCT05458843
- Testing
- Fluid replacement, No fluid replacement
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Indiana University
Weather Risk Perception
Perceptions of Weather Risks and Climate Beliefs Among the Hong Kong General Public
Background: Local abnormal heat events may be used as proxies for communicating the health impacts of climate change when people physically feel the effects to reduce the psychological distance of climate change and improve…
- Trial name
- NCT04919148
- Testing
- Heat risk and pro-environment behavior message
- Where
- Hong Kong
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Climate Change, Heat; Weather
Heat Adaptation Through Community-based Approaches and Research at SEACO: Structural and Behavioural Interventions (Heat Care)
The goal of this clinical trial is to learn if structural and behavioral interventions can mitigate the health effects of extreme heat in rural Malaysian communities.
- Conditions
- Climate Change, Heat; Weather, Heat Effect, Heat; Excess
- Trial name
- Heat Care (NCT06744309)
- Testing
- Heat Literacy Intervention, Structural (Cool Roof) Intervention
- Where
- Malaysia
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Monash University Malaysia
Hyperthermia, Weather; Heat
Efficacy of Electric Fans for Mitigating Thermal Strain in Older Adults During Heat Waves
With the increasing regularity and intensity of hot weather and heat waves, there is an urgent need to develop heat-alleviation strategies able to provide targeted protection for heat-vulnerable older adults.
- Conditions
- Hyperthermia, Weather; Heat, Heat Stress, Aging
- Trial name
- NCT05695079
- Testing
- No cooling (control), Electric fan (low airflow), Electric fan (high airflow)
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Quality of Life
Hot or Cold Beverages in Warm Weather
Some studies have suggested that hot beverages are better for cooling down when body temperature rises. No study has investigated the effect of hot beverages in hot weather on personal well-being compared to cold beverages.
- Trial name
- NCT05900960
- Testing
- Tea
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Heat Stress, Heat Exposure
Validity of Humidity Ramp Protocols for Identifying Limits of Survivability in Heat-exposed Persons
The global populace is at growing risk of heat-related illness due to climate change and accompanying increases in the intensity and regularity of extremely hot temperatures.
- Conditions
- Heat Stress, Heat Exposure, Temperature Change, Body, Temperature; Extreme, Exposure
- Trial name
- NCT05963529
- Testing
- Humidity-ramp protocol, Above-inflection fixed-condition exposure, Below-inflection fixed-condition exposure
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Hot Weather; Adverse Effect, Kidney Dysfunction
Renal Considerations in the Heat Stress Recommendations
An epidemic of chronic kidney disease is occurring in laborers who undertake physical work outdoors in hot conditions. The reason for this is unknown, but may be related to kidney dysfunction caused by increases in body…
- Conditions
- Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia
- Trial name
- Aim1 (NCT04767347)
- Testing
- 23.0°C WBGT - Fixed Work Rate, 25.5°C WBGT - Fixed Work Rate, 27.5°C WBGT - Fixed Work Rate
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Indiana University
Asthma
Testing the Effects of Temperature & Humidity on Children With and Without Asthma in an Environmental Climatic Chamber
The goal of this clinical study is to learn how different temperature and humidity conditions affect breathing, lung function, exercise capacity, symptoms, and other physical responses in children and youth aged 11 to 18 years…
- Trial name
- NCT07864506
- Testing
- Controlled Temperature and Humidity Exposure
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ontario Institute of Technology