Clinical trials: Weight
Polymorphism, Restriction Fragment Length
Relationship Between the VEGF Gene Polymorphism and Cardiometabolic Risk Factors
The aim of the study is to determine the relationship between VEGF gene expression, VEGF gene polymorphism and serum leptin concentration in the Polish population in people with excessive body weight.
- Trial name
- 27/MN/2018 (NCT04077554)
- Testing
- gene expression
- Where
- Poland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Body Weight Changes, Athletic Performance
Whey Protein Supplementation in High School Athletes
The overall aim of this project is to compare protein supplementation on performance, recovery, and body composition changes in adolescent soccer players between the whey protein and the control group in response to the…
- Conditions
- Body Weight Changes, Athletic Performance, Recovery, Sleep
- Trial name
- NCT05589129
- Testing
- Whey Protein Supplement
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity, Weight Loss
Bariatric Embolization Trial for the Obese Nonsurgical
The purpose of this study is to assess the safety profile of bariatric embolizations and confirm published reports of sustained post-procedural weight loss, and pathologically assess post-procedural metabolic effects.
- Conditions
- Obesity, Weight Loss, Body Weight, Morbid Obesity
- Trial name
- BET-ON (NCT03601273)
- Testing
- Left gastric artery embolization
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Healthy, Obesity
A Study to Test How Well Different Doses of BI 3034701 Are Tolerated by Japanese Healthy People and Japanese People With Obesity or Overweight
Part 1: To investigate safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of BI 3034701 in Japanese male and female participants with body mass index (BMI) ≥27.0 kg/m² or more following subcutaneous…
- Trial name
- NCT07693231
- Testing
- BI 3034701
- Where
- 3 sites in Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Overweight and Obesity
High Intensity Interval Training and Skeletal Muscle Insulin Sensitivity
This human intervention study will test if 12 weeks of supervised HIIT-based intervention improves skeletal muscle NOGD capacity in obese subjects.
- Trial name
- NCT03405545
- Testing
- High-intenstiy interval training
- Where
- Netherlands
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Healthy, Overweight
Study to Evaluate the Effect of Gum Acacia (FibregumTM) on Post-prandial Glucose, Insulin Levels and Food Intake
Study to evaluate the effect of gum acacia (FibregumTM) on post-prandial glucose and insulin levels and food intake in normal-weight and overweight subjects during a 2-7 weeks intervention period.
- Trial name
- NCT04515277
- Testing
- 40 g Gum acacia (FibregumTM), 20 g Gum acacia (FibregumTM), 0 g Gum acacia (FibregumTM)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nexira
Pregnancy Related, Sleep Disordered Breathing
The Sleep in Pregnancy Study
Sleep disordered breathing (SDB) insidiously worsens metabolic function, heightens insulin resistance (IR), and in pregnancy is thought to precipitate gestational diabetes, preterm birth, growth restriction, gestational…
- Conditions
- Pregnancy Related, Sleep Disordered Breathing, Obesity
- Trial name
- SiP (NCT03248219)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Overweight
Challenge!, a Health Promotion/ Obesity Prevention Program for Teens
The purpose of Challenge! is to determine if adolescents enrolled in a health promotion/ obesity prevention program will have a healthier BMI-for-age z-score and body composition (body fat %), will consume a healthier diet, and…
- Trial name
- NCT00746083
- Testing
- Challenge!
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Increase in Urobilinogen in Urine Prior to Delivery, Weight Loss After 37 Weeks Gestation Prior to Delivery
Urobilinogen, Maternal Weight Loss and Impending Parturition at Term
The purpose of this study, then, is to search existing clinic and hospital records for answers to the following two questions: (1) Do pregnant women who are at least 37 weeks gestation and who have an increase in urubilinogen on…
- Trial name
- NCT00826605
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Diet Modification, Physical Activity
Denver Garden Environment and Microbiome Study Disease
An interdisciplinary team with extensive garden study experience conducted a pilot randomized controlled clinical trial to see whether gardening reduced risk factors for diseases like cancer and heart disease.
- Conditions
- Diet Modification, Physical Activity, Weight Gain, Chronic Disease
- Trial name
- DGEM (NCT03089151)
- Testing
- Community Garden Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Obesity, Insulin Sensitivity, Type 2 Diabetes Mellitus
Dietary Polyphenols and Lipid Oxidation
There are strong indications that (combinations of) polyphenols may be attractive candidates in the prevention of the metabolic syndrome and diabetes through modulation of pathways of fatty acid metabolism and mitochondrial…
- Trial name
- NCT01302639
- Testing
- Comparison of different combinations of polyphenols with respect to effects on fat oxidation
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity
Discordance of Obesity in Adolescent Sibilngs
This research studies the energy balance behaviors (usual eating, physical activity, sedentary) and non-shared experiences of siblings discordant for weight (one sibling is lean the other is overweight).
- Trial name
- NCT02376439
- Testing
- Kool-aid
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Cardiovascular Diseases, Lipid Disorder
SRMA of the Effect of Soy Milk vs Cow's Milk on Cardiometabolic Outcomes
Dairy consumption has shown associations with decreased incidence of cardiometabolic diseases. With the growing interest in plant-based eating, and the mounting evidence for the cardiovascular benefits of plant forward diets…
- Conditions
- Cardiovascular Diseases, Lipid Disorder, Metabolic Disease, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT05637866
- Testing
- Soy milk
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Weight Loss
Effects of a Weight Loss Intervention in College-age Women
Determine the effects of an 8-week weight loss intervention.
- Trial name
- NCT02966431
- Testing
- Counseling, No Counseling
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Obesity
Promoting Healthy Weight Across the Pregnancy and Postpartum Period
This project evaluates the effectiveness of an evidence-based intervention (HEALTH-P2) to prevent excessive weight gain from pregnancy through 12 months postpartum when disseminated and implemented in real-world settings, through…
- Trial name
- HEALTH-P2 (NCT04253977)
- Testing
- HEALTH-P2, Usual Care
- Where
- United States
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Preterm Infant Development, Preterm Infant Feeding Outcomes
Estimation of Nutritional Needs of Preterm Neonates Fed on Parenteral Nutrition and Effects on Body Weight Gain
This randomized controlled trial included 100 preterm and small for gestational age neonates. The study aimed to determine the optimal approach for estimating nutritional needs in parenteral nutrition (PN) with the assistance of…
- Trial name
- NCT07236957
- Testing
- Intervention Group, Control group
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Panos Papandreou
Obesity, Sweeteners
Mapping the 'Sweet Brain' in Healthy Participants
The human brain has a central role in regulating appetite and food intake. It integrates many metabolic, hedonic and trait-related signals that affect eating behaviour and determine when and how much we eat.
- Trial name
- NCT04162457
- Testing
- Stevia, Glucose, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Healthy
The Effects of Acute Weight Gain and Acute Calorie Deprivation on Marrow Adipose Tissue
Marrow adipocytes have been identified as a component of the bone marrow micro-environment. Evidence exists suggesting that marrow fat plays an important physiologic role in both bone mineral and energy metabolism in humans.
- Trial name
- NCT02482519
- Testing
- High calorie diet, Fasting
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Diabetes Mellitus, Type 2, Obesity
Investigation Of Weight Loss And Body Composition Changes After Dosing With Either Placebo Or One Of Two Active Drugs
The drugs GSK189075 and GW869682 result in increased caloric losses. This study is investigating how if taken over 8 weeks that affects weight loss, food intake and the composition of the body.
- Trial name
- NCT00494767
- Testing
- GW869682, GSK189075
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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