Clinical trials: Weight Change Trajectory
Birth Weight, Weight Gain Trajectory
Effects of Monitoring Blood Pressure During Pregnancy
In this study, at least 400 women with high-risk of pregnancy hypertension will use a wearable device to monitor the blood pressure during gestational age from 12 weeks to 28weeks.
- Trial name
- NCT06217913
- Testing
- wearable device to monitor the blood pressure
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Pediatric Obesity, Weight Gain Trajectory
Assessing Better Bottles for Babies
This study will use a 2 x 2 factorial design to test impact of two intervention strategies (bottle size and bottle opacity) on infant weight gain.
- Conditions
- Pediatric Obesity, Weight Gain Trajectory, Infant Obesity
- Trial name
- AB3 (NCT06357299)
- Testing
- Small Bottle Size, Standard Bottle Size, Clear Bottle
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Pediatric Obesity
Factors Associated With Changes in Weight-status in Danish School Children With Obesity
Childhood obesity is increasing worldwide and causes a major health concern. Only limited insight exists into the natural history of childhood obesity at children already classified as obese.
- Trial name
- NCT06077266
- Testing
- Change of weight class to normal weight
- Where
- Denmark
- Volunteers
- 467 people
- Sponsor
- University of Aarhus
Triglycerides, Weight Gain Trajectory
Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists
The goal of this clinical trial is to learn if drug RDX-002 works to treat high levels of fat (known as triglycerides, or TGs) in the blood in adults. It will also learn about the safety of drug RDX-002.
- Conditions
- Triglycerides, Weight Gain Trajectory, Cholesterol, Elevated
- Trial name
- NCT06640972
- Testing
- RDX-002
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Response Pharmaceuticals
Type 2 Diabetes Mellitus
Weight Trajectory in New Users of Sulfonylureas as Add on Therapy Next to Metformin.
Next to HbA1c, body weight is regarded as an important surrogate end-point in trials investigating glucose-lowering agents. An increase in weight could contribute to worsening insulin resistance.
- Trial name
- ZODIAC-39 (NCT02133118)
- Testing
- individual SUs, insulin, pioglitazone
- Where
- Netherlands
- Volunteers
- 16,293 people
- Sponsor
- Medical Research Foundation, The Netherlands
Diabetes Mellitus, Type 2, Obesity
Microclinic Social Network Behavioral Health Trial in Jordan
This 3-armed randomized controlled trial aims to evaluate the effectiveness of The Microclinic Behavioral Health Program in improving obesity and diabetes risk factors through a behavioral intervention program structured to…
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Hyperglycemia
- Trial name
- NCT01818674
- Testing
- Microclinic Behavioral Health Full Program (education curriculum in classroom setting, plus full social interaction program), Microclinic Behavioral Health Basic Program (education-only in classroom setting; no structured social interactions)
- Where
- 3 sites in Jordan
- Volunteers
- 914 people
- Sponsor
- Microclinic International
Pancreatic Ductal Adenocarcinoma (PDAC), Hand Grip Strength
Using Strength Tests to Better Understand How Pancreatic Cancer Affects Muscle Mass and Quality of Life
The goal of this clinical trial is to measure hand grip strength in adults with pancreatic ductal adenocarcinoma (PDAC). The main questions it aims to answer are: Is it feasible to measure hand grip strength as part of a clinic…
- Trial name
- PanFit (NCT07255001)
- Testing
- Hand grip strength assessments using a dynamometer
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Responsive Feeding, Infants
Learning Early Infant Feeding Cues
The goal of this clinical trial is to learn more about responsive infant feeding (recognizing baby's signs of hunger and fullness) in mothers and infant enrolled in government-funded maternal-child home visiting programs.
- Conditions
- Responsive Feeding, Infants, Weight Gain Trajectory
- Trial name
- LEIFc (NCT06127914)
- Testing
- Learning Early Infant Feeding Cues
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Florida State University
Body-Weight Trajectory
Impact of Health Lifestyle on Body Weight
Pharmacotherapy becomes an important and effective approach to improve body weight. However, it still remains unclear how to manage potential fluctuation after its cessation.
- Trial name
- NCT05608226
- Testing
- Lifestyle Education Program
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Shanghai Zhongshan Hospital
Weight Trajectory
Gamma-linolenic Acid Supplementation Study
Weight regain following weight loss is common. In rodent models of obesity and pilot studies in humans, increasing membrane arachidonic acid content improves fuel partitioning and prevents weight regain.
- Trial name
- GLASS (NCT04481724)
- Testing
- gamma-linolenic acid
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- Virta Health
Obesity, Adolescent Obesity
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond…
- Conditions
- Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory
- Trial name
- PRESSURE (NCT06575738)
- Testing
- Injectable semaglutide or injectable tirzepatide, Standard postoperative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Obesity
A Study to Investigate Why Overweight People Regain Weight After Losing Weight in a Behavioral Weight Loss Program
The goal of this clinical trial is to determine the physiological basis for the differences in weight regain among adults (25-59 years old) with obesity following participation in a behavioral weight loss program.
- Trial name
- POWERS (NCT05748158)
- Testing
- Weight loss
- Where
- 3 sites in United States
- Volunteers
- 205 people
- Sponsor
- University of Pittsburgh
GLP-1, Weight Loss Trajectory
Evaluation of a Nutritional Intervention With Dietary Supplements in People Who Have Recently Lost Weight: Effects on Body Composition, Emotional Health, and Gut Microbiota
This study aims to evaluate the effects of a 12-week nutritional intervention with dietary supplements on individuals who have experienced significant weight loss following the use of GLP-1 receptor agonists or similar…
- Conditions
- GLP-1, Weight Loss Trajectory, Emotional Disorder, Microbiota Balance
- Trial name
- NCT07269821
- Testing
- Metabolaid®-based nutraceutical formulation
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- University of Alicante
Weight Change, Body
Microbiome and Bariatric Surgery
This is a prospective, 24-month, longitudinal study of patients planning to undergo bariatric surgery (Roux-en-Y Gastric Bypass or Sleeve Gastrectomy) in which we aim to identify correlates and predictors of observed weight loss…
- Trial name
- Biobehavioral (NCT03065426)
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- North Dakota State University
Weight Gain Trajectory, Metabolic Syndrome
Study of a Prebiotic Supplement to Mitigate Excessive Weight Gain Among Physicians in Residency
A randomized placebo controlled trial to determine if increased dietary fiber will prevent weight gain, inhibit adiposity and reduce perceived stress levels in residents at the Waco Family Health Center as the result of changes…
- Trial name
- NCT04498455
- Testing
- Prebiotin
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Baylor University
Weight Gain Trajectory, BMI
Evaluating Care Integration Between Pediatric Primary Care Providers and WIC Nutritionists
This study looks at whether using secure digital systems to share information between pediatric health care providers (during regular well-child visits) and social care providers (during regular visits with WIC nutritionists) can…
- Conditions
- Weight Gain Trajectory, BMI, Responsive Parenting, Diet Quality
- Trial name
- WEE Baby (NCT07494097)
- Testing
- Data integration around responsive parenting, Standard Care (in control arm)
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Penn State University
Pregnancy Complications, Pregnancy Related
Sleep and Tracking Effects in Pregnancy Study
Purpose: The investigators hypothesize that a simple, personalized, smartphone-based activity intervention using a wrist-based activity tracker will help high risk pregnant women reduce their stress during pregnancy.
- Conditions
- Pregnancy Complications, Pregnancy Related, Weight Gain, Weight Change Trajectory
- Trial name
- STEP (NCT04173559)
- Testing
- Activity Intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Obesity; Drug
Latino Semaglutide Study
The purpose of this study to understand better how this anti-obesity medication works to assist individuals to lose weight and maintain weight loss.
- Conditions
- Obesity, Obesity; Drug, Overweight or Obesity, Weight Loss
- Trial name
- LSS (NCT05087342)
- Testing
- Semaglutide 2.4mg
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Loma Linda University
Locally Advanced Gastric Cancer, Trajectory
Trajectory of Body Composition Identifies LAGC with Cachexia Following NACT
This longitudinal, multicentre cohort study included LAGC patients treated with NACT between 01/2010-12/2021. BC measurements including skeletal muscle mass (SMM) and total adipose tissue area (TATA) were evaluated by computed…
- Trial name
- FJMUGS-2411 (NCT06716593)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Chang-Ming Huang, Prof.
Obesity, Weight Change Trajectory
Evaluation of the Safety and Efficacy of Revita® DMR on Body Weight Maintenance in Subjects With Obesity Who Have Achieved at Least 15% Weight Loss on Tirzepatide
Fractyl is evaluating Revita Duodenal Mucosal Resurfacing (DMR) in the REMAIN-1 pivotal study, which is designed to include two cohorts - an open label cohort referred to as REVEAL-1, and a randomized cohort, which includes both…
- Conditions
- Obesity, Weight Change Trajectory, Weight Change, Body
- Trial name
- REMAIN-1 (NCT06484114)
- Testing
- Revita Duodenal Mucosal Resurfacing (DMR)
- Where
- 32 sites in United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Fractyl Health Inc.