Clinical trials: Weight Changes, Body
Obesity, Bariatric Surgery
Protein Need and Interest of " Quick Proteins " to the Obese Subject Operated by Bariatric Surgery (BIBOP)
The main objective of the study is to evaluate the protein requirement associated with postoperative weight loss caused by by-pass (shunt which leads to a certain degree of malabsorption) or sleeve gastrectomy (more technically…
- Trial name
- BIBOP (NCT01249326)
- Testing
- bariatric surgery
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Clermont-Ferrand
Weight Loss
The Effect of Weight Loss on Ovarian Reserve
Obesity affects on fertility. Obese women have lower pregnancy rate after infertility treatments.They need more doses of hormone during ovarian stimulation, more days for stimulation.
- Trial name
- NCT01844128
- Testing
- weight loss
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Weight Gain
Caregiver Led Strategies to Malnutrition and Care-giving Among Children With Cerebral Palsy
The goal of this factorial trial is to test and compare the effectiveness of two caregiver led strategies, i.e., the positive deviance nutrition(PD) strategy and the parent facilitator training (PFT) strategies, to malnutrition…
- Trial name
- NCT05592834
- Testing
- positive deviance hearth strategy, Parent facilitator trainings, Control
- Where
- Uganda
- Volunteers
- 124 people
- Sponsor
- Makerere University
Obesity, Metabolic Syndrome
Impact of Metabolic Flexibility on Changes in Metabolic Health
Metabolic flexibility is the capacity to adapt fuel oxidation to fuel availability so that ATP synthesis can match its cellular demands.
- Trial name
- METPROS (NCT06340321)
- Testing
- Metabolic flexibility in the fasted state, Metabolic flexibility in euglycemic-hyperinsulinemic clamp, Metabolic flexibility in the metabolic chamber
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users
This study aims to assess the impact of GLP-1 receptor agonists, semaglutide and tirzepatide, on food cravings and diet quality in individuals with overweight or obesity.
- Trial name
- NCT06467604
- Testing
- Surveys, Indirect Calorimetry, Body composition
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity, Knee Osteoarthritis
BLOOM Forward: Investigating Weight Loss Impact on TJAC Patients
The goal of this clinical trial is to prospectively assess the efficacy of the BLOOM program, a comprehensive weight loss dietary and lifestyle program, in a population of patients living with obesity and awaiting hip or knee…
- Conditions
- Obesity, Knee Osteoarthritis, Hip Osteoarthritis, Arthroplasty Complications
- Trial name
- NCT06103552
- Testing
- Building Lifestyle Options for Orthopedic Mobility (BLOOM)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Obesity, Obesity, Morbid
Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss
The Investigators propose suture plication placement at the distal gastric body drives a significant portion of weight loss in endoscopic sleeve and sutures only need to be placed in the distal gastric body.
- Conditions
- Obesity, Obesity, Morbid, Metabolic Disease, Weight, Body
- Trial name
- NCT06299644
- Testing
- Endoscopic Sleeve Gastroplasty - Belt and Suspenders, Endoscopic Sleeve Gastroplasty - Belt
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Metabolic Syndrome
Canadian Health Advanced By Nutrition and Graded Exercise
The overall objective of the CHANGE initiative is to change the delivery of care in primary care clinics to treat disease by reducing reliance on drugs and hospitals through the promotion of scientifically validated nutritional…
- Trial name
- CHANGE (NCT01616563)
- Testing
- Dietary Intervention, Exercise Prescription and Fitness Program
- Where
- 3 sites in Canada
- Volunteers
- 305 people
- Sponsor
- Daren K. Heyland
Obesity, Overweight
Transoral Gastric Volume Reduction as an Intervention for Weight Management
This study assesses weight loss from the Endoscopic Vertical Gastroplasty or Fogel Gastroplasty (FG). The purpose of the study is to: Document that weight loss occurs (12 months) Determine if it alters general wellbeing…
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT02578836
- Testing
- Fogel Gastroplasty
- Where
- United States
- Sponsor
- University of Miami
Severe Acute Malnutrition
Ready to Use Therapeutic Food (RUTF) in Severe Malnourished Children
1. RUTF would be more effective (quicker catch-up growth by promoting more tissue accrue resulting decrease stay in rehabilitation ward) in treating children with SAM during the rehabilitation phase than khichuri /halwa; 2.
- Trial name
- RUTF (NCT01331044)
- Testing
- Plumpy Nut, Khichuri and Halwa
- Where
- Bangladesh
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Obesity
FB4 (Framingham, Boston, Bloomington, Birmingham, and Baylor)
This study will evaluate the effects of dietary carbohydrate and sugar consumption, independent of energy content, on body fatness and metabolism in a rigorous feeding study.
- Trial name
- NCT03394664
- Testing
- Feeding Study
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cachexia
Study of Comparative Bioavailability and Pharmacokinetics of ACM-001.1) and Pindolol in Healthy Volunteers (HV)
The aim of this early phase two-part study was to compare the bioavailability (BA) pharmacokinetics (PK) and pharmacodynamics (PD) of racemic pindolol with the benzoate salt of the S-enantiomer of pindolol (ACM-001.1) and provide…
- Trial name
- NCT06028321
- Testing
- Part 1 Group 1 Regime A (ACM-001.1), Part 1 Group 2 Regimen C (Pindolol), Part 2 Group D (Pindolol)
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Actimed Therapeutics Ltd
Obesity, Diabetes
Effect of Pomegranate Extract Intake on Body Composition and Blood Pressure.
Pomegranate has gained widespread popularity since the health effects of the whole fruit, as well as its juices and extracts, have been studied in relation to a variety of chronic conditions such as hypertension, diabetes…
- Conditions
- Obesity, Diabetes, Cardiovascular Disease
- Trial name
- NCT02017132
- Testing
- Pomegranate extract
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Obesity
Effect of Diltiazem Administration on CP-945,598 Pharmacokinetics
A recently completed clinical drug interaction study of CP-945,598 with ketoconazole, a potent CYP3A inhibitor, showed that coadministration of CP-945,598 with ketoconazole results in an approximately 5-fold increase in…
- Trial name
- NCT00645463
- Testing
- CP-945,598
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cachexia
Single and Multiple Ascending Dose Study of NGM120 in Healthy Adult Subjects
The purpose is to evaluate the safety, tolerability, and PK of NGM120 in healthy adult subjects
- Trial name
- NCT03392116
- Testing
- NGM120
- Where
- Australia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- NGM Biopharmaceuticals, Inc
Cancer
The FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms"
The aim of the study is to identify how often gastrointestinal problems interfere with quality of life as a result of treatment for cancer with chemotherapy.
- Trial name
- FOCCUS (NCT02121626)
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Obesity
Effect of Low-calorie Diet and Orange Juice on Body Weight and Metabolic Parameters of Obese Subjects
This study aimed to verify if combination of a low calorie diet and orange juice consumption results in weight loss and ameliorates metabolic obesity-related biomarkers.
- Trial name
- LCD-OJ-OBESE (NCT02914249)
- Testing
- Orange juice (500 mL/d)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Trans Epidermal Water Loss
Effect of Twice Daily Application of Coconut Oil in Reducing Water Loss From Skin of Premature Babies in First Week of Life
The skin of newborn infants is immature and ineffective as a barrier. Preterm skin exhibits even more vulnerability to the environment due to poor self regulatory heat mechanisms, paucity of fatty tissue and its thinness.
- Trial name
- TEWL (NCT01758068)
- Testing
- Coconut Oil Application
- Volunteers
- 74 people
- Sponsor
- Lady Hardinge Medical College
Autism Spectrum Disorder, Obesity
Open Trial Obesity CHANGE Program ASD
The purpose of this study is to determine if a program can help children with autism who are overweight. Specifically, this study will look to see if changes in a child's eating habits and exercise can help with weight loss.
- Trial name
- NCT03047018
- Testing
- The Changing Health in Autism through Nutrition, Getting fit and Expanding variety (CHANGE) Program
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Obesity, HIV-1-infection
Semaglutide's Efficacy in Achieving Weight Loss for Those With HIV
The prevalence of obesity is rising worldwide, both in low- and high-income countries, including people with HIV (PWH). Semaglutide's efficacy in achieving weight loss in obese PWH is still unexplored.
- Trial name
- SWIFT (NCT04174755)
- Testing
- Semaglutide Injectable Product, Standard of care
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- University College Dublin
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