Clinical trials: Weight Changes, Body
Obesity, Morbid, Weight Regain After Bariatric Surgery
Weight Loss and Comorbidity Outcomes After Revisional Bariatric Surgery
Some people who have had weight-loss (bariatric) surgery do not lose enough weight, regain much of the weight they lost, see obesity-related diseases such as diabetes or high blood pressure return, or develop complications of the…
- Conditions
- Obesity, Morbid, Weight Regain After Bariatric Surgery, Insufficient Weight Loss After Bariatric Surgery, Complication of Bariatric Surgery
- Trial name
- NCT07880691
- Testing
- Revisional bariatric surgery
- Volunteers
- 96 people
- Sponsor
- Kasr El Aini Hospital
Joint Osteoarthritis, Atherosclerosis of the Distal Arteries, Without Gangrene
Evaluation of Impaired Mobility in Chronic Illness Constitution of a Cohort
Chronic illness is a public health issue and mobility loss is frequent in this population. Among its' multiple physical and psychological consequences, increased mortality and cardiovascular morbidity seem the main concern.
- Conditions
- Joint Osteoarthritis, Atherosclerosis of the Distal Arteries, Without Gangrene, Parkinson Disease, Chronic Obstructive Pulmonary Disease, Unspecified
- Trial name
- EVALMOB (NCT04375280)
- Testing
- Development of a screening algorithm designed to determine a "dysmobility" profile in patients with chronic illness.
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Insulin Sensitivity
Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
The goal of this intervention study is to learn about how weight loss impacts molecular signaling of intermuscular adipose tissue (IMAT) in individuals with obesity.
- Conditions
- Obesity, Insulin Sensitivity, Muscle Weakness, Adiposity
- Trial name
- NCT06129110
- Testing
- Diet Weight Loss
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Overweight, Obesity
Evaluation of the Remote Intervention for Diet and Exercise (RIDE)
A large proportion of the adult population in the United States qualifies for weight loss treatment based on the NIH treatment recommendations, but traditional clinic-based weight loss treatments have a number of limitations.
- Trial name
- RIDE (NCT00883350)
- Testing
- RIDE e-health application
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Cannabis Use, Cachexia; Cancer
Safety and Efficacy of Inhaled Synthetic THC/CBD for Improving Physical Functioning and for Modulating Cachexia Progression in Patients With Advanced Cancer and Associated Cachexia
A large number of patients with advanced cancer also suffer from cachexia. Cachexia is a syndrome characterized by loss of skeletal muscle mass (with/or without loss of fat mass) that cannot be reversed by nutritional support and…
- Conditions
- Cannabis Use, Cachexia; Cancer, Advanced Cancer
- Trial name
- SERENITY (NCT04001010)
- Testing
- PPP011
- Where
- Canada
- Volunteers
- 334 people
- Sponsor
- Tetra Bio-Pharma
Obesity, Heart Diseases
The Effect of Xenical on Weight and Risk Factors
The purpose of this study is to determine the effect of using the weight loss medication Xenical (generic name - orlistat) on weight loss and change in heart disease risk factors in patients of the Healthy Heart Program Lipid…
- Trial name
- NCT00152360
- Testing
- Orlistat
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obesity & Overweight
Changes in Intestinal Permeability and Systemic Inflammation Following Fast Food Overfeeding.
The purpose of this study is to investigate whether lifestyle factors can alter gut barrier integrity and whether disruptions of the gut barrier can trigger systemic and tissue-specific inflammation.
- Trial name
- ChIPS (NCT07893743)
- Testing
- Fast-food overfeeding
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Obesity, Nutrition Poor
Healthy Frio: A Rural Community Partnership to Advance Latino Obesity Research
Much has been learned about the efficacy and effectiveness of comprehensive healthy lifestyle interventions to reduce obesity. Few studies have been translated into rural settings or among Latinos.
- Conditions
- Obesity, Nutrition Poor, Physical Activity, Weight Loss
- Trial name
- NCT03186885
- Testing
- Healthy Frio In-Person Family-focused Intervention, Healthy Frio Remote Technology Family-focused Intervention, Control
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Texas at Austin
Obesity
Game of Stones: A Research Study That Texts Men to Help Them Lose Weight
In 2014, 24% of UK men were obese. However men rarely participate in weight loss programmes. This study looks at whether two interventions which show promise can help obese men lose weight and keep it off.
- Trial name
- NCT03040518
- Testing
- Narrative SMS, Endowment Incentive
- Where
- 2 sites in United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Overweight, Obese
Effects of Journaling on Weight Loss
This is a randomized controlled trial with enhanced usual care treatment control. The aim is to determine the effects of journaling and use of resource website on weight loss. There will be two groups of 55 participants each.
- Trial name
- NCT01660685
- Testing
- Tracking, Journaling, Website
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Milton S. Hershey Medical Center
Diabetes, Heart Diseases
Personalized Responses to Dietary Composition Trial 3
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT04735835
- Testing
- Dietary Intervention
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Obese, Weight Loss
Efficacy of Henagliflozin for Weight Loss in Obesity Without Diabetes
This trial is conducted in China. The purpose of the 24-week trial is to investigate the efficacy of henagliflozin to induce body weight loss and the purpose of the extension is to evaluate the hypoglycemic effect of…
- Conditions
- Obese, Weight Loss, Pre-diabetes
- Trial name
- NCT06216340
- Testing
- Henagliflozin
- Volunteers
- 300 people
- Sponsor
- The First People's Hospital of Changzhou
Weight Loss
Does Dapagliflozin Promote Favorable Health Benefits That Are Independent Of Weight Loss?
Th mechanism of action of dapagliflozin is via sodium-glucose co-transporter 2 (SGLT2) inhibition. Sodium-glucose co-transporter 2 inhibition is associated with moderate weight (fat) loss, in addition to other health benefits…
- Trial name
- NCT02520518
- Testing
- Dapagliflozin, Weight maintenance, Ad libitum dietary intake
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Christopher Bell
Overweight, Obesity
Effect of Daily Glucomannan in Overweight Patients
Glucomannan is a dietary supplement that has been marketed for weight loss. There is some research that supports this claim but more research is necessary.
- Trial name
- NCT01485718
- Testing
- Glucomannan
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ProMedica Health System
Morbid Obesity, Diabetes
Factors Influencing the Positive Outcome of Bariatric Surgery for Morbidly Obese Patients
The purpose of this study is to report data with patients after bariatric surgery.
- Conditions
- Morbid Obesity, Diabetes, Hypertension
- Trial name
- NCT01583790
- Where
- Israel
- Volunteers
- 2,000 people
- Sponsor
- Assuta Hospital Systems
Arthropathy, Incision, Surgical
Approach Modification for Total Knee Arthroplasty in Morbidly Obese Patients
The study provides a detailed description of a smaller incision with better visualization in total knee arthroplasty operations
- Conditions
- Arthropathy, Incision, Surgical, Obesity, Morbid
- Trial name
- NCT05840705
- Testing
- Small curved incision with apex lateral
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Weight Loss, Other Effects of High Altitude
Substrate Utilization, Exercise Performance, and Skeletal Muscle Response to Energy Deficit and Altitude Acclimatization
This research will evaluate nutrition requirements for missions at high altitude (i.e. >7800 feet above sea level) and the information obtained can be used to optimize nutrient content specifications for combat rations.
- Trial name
- NCT02731066
- Testing
- Standard pro, High pro, carbo bev
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Metabolic Syndrome, Insulin Resistance
Study of How Exercise or Weight Loss Effects Metabolic Syndrome
The Metabolic Syndrome (MS) is prevalent in the American population and is strongly associated with premature coronary disease. Lifestyle intervention, primarily exercise and dietary changes, are foundational treatment strategies…
- Conditions
- Metabolic Syndrome, Insulin Resistance, Obesity
- Trial name
- NCT00292994
- Testing
- Exercise, Weight Loss
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Yankton Clinical Research Alliance
Weight Gain, Pregnancy Related
Healthy for Two, Healthy for You
Investigators conducted a pilot feasibility and acceptability randomized controlled trial of a remotely delivered behavioral health coaching program in pregnancy and postpartum.
- Trial name
- H42/H4U (NCT03551054)
- Testing
- Healthy for Two, Healthy for You, Health Education
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Childhood Obesity
Adaptive Mechanisms Responsible for Weight Change in Youth With Obesity
In this study, doctors want to find out more about why people who lose weight often regain the weight that they have lost once they resume a regular diet and whether hormones might play a role in weight regain.
- Trial name
- ADMIRE (NCT05125822)
- Testing
- Meal replacement and lifestyle modification
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
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